| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abiraterone acetate_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA8 | heat shock 70kDa protein 8 | 0.0641388 |
| TOP1 | topoisomerase (DNA) I | 0.0463935 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0343583 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0339563 |
| MYO5B | myosin VB | 0.0319461 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0294907 |
| GDF15 | growth differentiation factor 15 | 0.0274626 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0271012 |
| EREG | epiregulin | 0.0263783 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0259528 |
| AREG | amphiregulin | 0.0252487 |
| RPL3 | ribosomal protein L3 | 0.0247166 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0244144 |
| RPL13A | ribosomal protein L13a | 0.0223788 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0213338 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0210707 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0208792 |
| OGA | O-GlcNAcase | 0.0205413 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0205297 |
| RBM26 | RNA binding motif protein 26 | 0.020503 |
| LAMB3 | laminin, beta 3 | 0.0189837 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0184754 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0183174 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0182968 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0182829 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0179325 |
| RNF43 | ring finger protein 43 | 0.0176137 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0175471 |
| PLEC | plectin | 0.0173342 |
| LMO7 | LIM domain 7 | 0.0171059 |
| ATL2 | atlastin GTPase 2 | 0.0168392 |
| ATP11B | ATPase, class VI, type 11B | 0.0162396 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | 0.0161364 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0159244 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0155659 |
| GRHL3 | grainyhead-like 3 (Drosophila) | 0.0155554 |
| HLA-C | major histocompatibility complex, class I, C | 0.0155256 |
| ANXA1 | annexin A1 | 0.015474 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0153324 |
| CTBP2 | C-terminal binding protein 2 | 0.0151318 |
| RAB10 | RAB10, member RAS oncogene family | 0.0150925 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0150819 |
| WDR45B | WD repeat domain 45B | 0.0150673 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0150061 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0149817 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0147932 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0147552 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0145586 |
| RNF145 | ring finger protein 145 | 0.0141928 |
| MPZL3 | myelin protein zero-like 3 | 0.0138079 |
| CLTC | clathrin, heavy chain (Hc) | 0.0136437 |
| GOLGA4 | golgin A4 | 0.0134734 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0134279 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0133293 |
| RPL29 | ribosomal protein L29 | 0.0132805 |
| MSI2 | musashi RNA-binding protein 2 | 0.0131752 |
| ARRDC3 | arrestin domain containing 3 | 0.0131631 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.013149 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0130776 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0130513 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0127012 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | 0.0125705 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0125525 |
| RUNX2 | runt-related transcription factor 2 | 0.0122732 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.0121379 |
| RANBP9 | RAN binding protein 9 | 0.0118254 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.0116624 |
| FOXO1 | forkhead box O1 | 0.0115411 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0115225 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.011449 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0113583 |
| INSIG2 | insulin induced gene 2 | 0.0113206 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0112598 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.0111775 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0108497 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.010754 |
| NFXL1 | nuclear transcription factor, X-box binding-like 1 | 0.0106459 |
| SERINC5 | serine incorporator 5 | 0.0105872 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0105825 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0105744 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0104257 |
| ADSS2 | adenylosuccinate synthase 2 | 0.0104165 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0104068 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0104035 |
| RPL14 | ribosomal protein L14 | 0.0103433 |
| RPL34 | ribosomal protein L34 | 0.0103178 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0102525 |
| NUP160 | nucleoporin 160kDa | 0.0101611 |
| EVA1C | eva-1 homolog C (C. elegans) | 0.0100618 |
| USP3 | ubiquitin specific peptidase 3 | 0.0100434 |
| GTF2I | general transcription factor IIi | 0.0099869 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0099786 |
| RACK1 | receptor for activated C kinase 1 | 0.00995772 |
| RREB1 | ras responsive element binding protein 1 | 0.00994728 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.00993347 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | 0.0098513 |
| PRPF39 | pre-mRNA processing factor 39 | 0.00984126 |
| RPS7 | ribosomal protein S7 | 0.00983299 |
| SRP54 | signal recognition particle 54kDa | 0.00970496 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.009693 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.144815 |
| HMGA2 | high mobility group AT-hook 2 | -0.122333 |
| PTMA | prothymosin, alpha | -0.118473 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0977821 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0766561 |
| ACTG1 | actin gamma 1 | -0.0755418 |
| RAD51B | RAD51 paralog B | -0.0754431 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0713809 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0710316 |
| FHIT | fragile histidine triad | -0.0691856 |
| EGR1 | early growth response 1 | -0.06728 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0652544 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0649551 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0621172 |
| RPS6 | ribosomal protein S6 | -0.0584915 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0551296 |
| EZR | ezrin | -0.0546416 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0545788 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0507586 |
| LAMA4 | laminin, alpha 4 | -0.0507304 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0503299 |
| IER3 | immediate early response 3 | -0.0488423 |
| ATXN1 | ataxin 1 | -0.0465085 |
| CD9 | CD9 molecule | -0.0464824 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0462382 |
| EXOC4 | exocyst complex component 4 | -0.0429148 |
| SMYD3 | SET and MYND domain containing 3 | -0.0428224 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | -0.0411892 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0398762 |
| GPHN | gephyrin | -0.0397791 |
| FERMT1 | fermitin family member 1 | -0.0395711 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0394653 |
| CUX1 | cut-like homeobox 1 | -0.0391011 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0378935 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0371706 |
| CDK13 | cyclin-dependent kinase 13 | -0.0369149 |
| VMP1 | vacuole membrane protein 1 | -0.0358071 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0357287 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0357118 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0347689 |
| FOSL1 | FOS-like antigen 1 | -0.0347052 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0345681 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0345041 |
| USP34 | ubiquitin specific peptidase 34 | -0.0336699 |
| S100A10 | S100 calcium binding protein A10 | -0.0330406 |
| VCL | vinculin | -0.0328589 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0322822 |
| S100A6 | S100 calcium binding protein A6 | -0.0322182 |
| TENM3 | teneurin transmembrane protein 3 | -0.0314763 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0310117 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0306629 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0302879 |
| RCOR1 | REST corepressor 1 | -0.0294072 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0293372 |
| BPTF | bromodomain PHD finger transcription factor | -0.0291742 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0291464 |
| TPM4 | tropomyosin 4 | -0.0287108 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0281178 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0279027 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0278455 |
| CANX | calnexin | -0.0277285 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0276578 |
| RPLP1 | ribosomal protein, large, P1 | -0.027651 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0271165 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0267722 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0267097 |
| EMP1 | epithelial membrane protein 1 | -0.0265727 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0265254 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0263427 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0260704 |
| RPS8 | ribosomal protein S8 | -0.0260683 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0259938 |
| ACTN4 | actinin, alpha 4 | -0.0259632 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0259268 |
| RPS24 | ribosomal protein S24 | -0.0256927 |
| EHBP1 | EH domain binding protein 1 | -0.0255662 |
| CD44 | CD44 molecule (Indian blood group) | -0.0254696 |
| AHNAK | AHNAK nucleoprotein | -0.024825 |
| MTAP | methylthioadenosine phosphorylase | -0.024718 |
| DIAPH2 | diaphanous-related formin 2 | -0.0245458 |
| RPS29 | ribosomal protein S29 | -0.0243976 |
| RPS25 | ribosomal protein S25 | -0.0243337 |
| RPL8 | ribosomal protein L8 | -0.0241255 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0239613 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0238517 |
| RPS23 | ribosomal protein S23 | -0.0234191 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0233248 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0232323 |
| RPS15 | ribosomal protein S15 | -0.0230947 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0230856 |
| RPS11 | ribosomal protein S11 | -0.023027 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0229761 |
| FOXP1 | forkhead box P1 | -0.0229094 |
| TMSB10 | thymosin beta 10 | -0.0228959 |
| FUS | FUS RNA binding protein | -0.0228659 |
| GPC5 | glypican 5 | -0.0225955 |
| NFIB | nuclear factor I/B | -0.022582 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0223442 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0222278 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0220684 |
