| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/71158 |
| Similar Terms | |
| Downloads & Tools |
197 proteins with high or low expression in Acamprosate relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TTLL4 | tubulin tyrosine ligase-like family member 4 | 1.35 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 0.72 |
| TTC7A | tetratricopeptide repeat domain 7A | 0.69 |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 | 0.67 |
| CRYBG2 | crystallin beta-gamma domain containing 2 | 0.64 |
| ARHGAP19 | Rho GTPase activating protein 19 | 0.6 |
| USP31 | ubiquitin specific peptidase 31 | 0.55 |
| AEBP2 | AE binding protein 2 | 0.55 |
| PLK1 | polo-like kinase 1 | 0.51 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.51 |
| RNF187 | ring finger protein 187 | 0.5 |
| KSR2 | kinase suppressor of ras 2 | 0.49 |
| ALG5 | ALG5, dolichyl-phosphate beta-glucosyltransferase | 0.48 |
| KIAA1107 | KIAA1107 | 0.47 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.47 |
| PTTG1 | pituitary tumor-transforming 1 | 0.45 |
| FDX1 | ferredoxin 1 | 0.44 |
| CNPY2 | canopy FGF signaling regulator 2 | 0.43 |
| CCNB1 | cyclin B1 | 0.43 |
| KNSTRN | kinetochore-localized astrin/SPAG5 binding protein | 0.43 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.43 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 0.43 |
| HOXA10 | homeobox A10 | 0.43 |
| CKM | creatine kinase, muscle | 0.42 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.42 |
| TBCA | tubulin folding cofactor A | 0.42 |
| NPHP3 | nephronophthisis 3 (adolescent) | 0.41 |
| ENO1 | enolase 1, (alpha) | 0.41 |
| YBX1 | Y box binding protein 1 | 0.4 |
| SACK1D | scaffolding CK1 anchoring protein D | 0.4 |
| MPHOSPH9 | M-phase phosphoprotein 9 | 0.4 |
| RGN | regucalcin | 0.39 |
| ATP5F1D | ATP synthase F1 subunit delta | 0.39 |
| MTFR2 | mitochondrial fission regulator 2 | 0.39 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.38 |
| CDC20 | cell division cycle 20 | 0.38 |
| TMEM147 | transmembrane protein 147 | 0.37 |
| SNRNP35 | small nuclear ribonucleoprotein 35kDa (U11/U12) | 0.37 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 0.37 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | 0.37 |
| NDUFS6 | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) | 0.36 |
| GTSE1 | G-2 and S-phase expressed 1 | 0.36 |
| ACD | adrenocortical dysplasia homolog (mouse) | 0.36 |
| ZNF142 | zinc finger protein 142 | 0.36 |
| CCNB2 | cyclin B2 | 0.35 |
| SET | SET nuclear proto-oncogene | 0.35 |
| ZXDC | ZXD family zinc finger C | 0.35 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.34 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.34 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.34 |
| DIXDC1 | DIX domain containing 1 | 0.34 |
| CTBS | chitobiase, di-N-acetyl- | 0.33 |
| SOD1 | superoxide dismutase 1, soluble | 0.33 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.33 |
| CCNA1 | cyclin A1 | 0.33 |
| MT2A | metallothionein 2A | 0.33 |
| KIF20A | kinesin family member 20A | 0.33 |
| SLC25A39 | solute carrier family 25, member 39 | 0.33 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.33 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | 0.32 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.32 |
| GTSF1 | gametocyte specific factor 1 | 0.32 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.32 |
| RBIS | ribosomal biogenesis factor | 0.32 |
| TPX2 | TPX2, microtubule-associated | 0.32 |
| FAM8A1 | family with sequence similarity 8, member A1 | 0.31 |
| INCENP | inner centromere protein antigens 135/155kDa | 0.31 |
| CDCA8 | cell division cycle associated 8 | 0.31 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.31 |
| POC1B | POC1 centriolar protein B | 0.31 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | 0.31 |
| PDP2 | pyruvate dehyrogenase phosphatase catalytic subunit 2 | 0.3 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | 0.3 |
| ZNRD1 | zinc ribbon domain containing 1 | 0.3 |
| CCNA2 | cyclin A2 | 0.3 |
| LZTS1 | leucine zipper, putative tumor suppressor 1 | 0.3 |
| CENPJ | centromere protein J | 0.3 |
| ZNF335 | zinc finger protein 335 | 0.3 |
| KIF22 | kinesin family member 22 | 0.3 |
| MKI67 | marker of proliferation Ki-67 | 0.3 |
| ZNF2 | zinc finger protein 2 | 0.3 |
| MTBP | MDM2 binding protein | 0.29 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.29 |
| ZNF543 | zinc finger protein 543 | 0.29 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 0.29 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.29 |
| DOP1A | DOP1 leucine zipper like protein A | 0.28 |
| SUMO3 | small ubiquitin-like modifier 3 | 0.28 |
| KMT5A | lysine methyltransferase 5A | 0.28 |
| PHF19 | PHD finger protein 19 | 0.28 |
| FAM86B2 | family with sequence similarity 86, member B2 | 0.28 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.28 |
| CDCA2 | cell division cycle associated 2 | 0.28 |
| SMTN | smoothelin | 0.28 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.28 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | 0.28 |
| ETV3 | ets variant 3 | 0.28 |
| ANLN | anillin, actin binding protein | 0.28 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.28 |
| APEX2 | APEX nuclease (apurinic/apyrimidinic endonuclease) 2 | 0.27 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -1.4 |
| PIP | prolactin-induced protein | -1.25 |
| PRODH | proline dehydrogenase (oxidase) 1 | -1.1 |
| E2F7 | E2F transcription factor 7 | -0.96 |
| FAM161A | family with sequence similarity 161, member A | -0.93 |
| ARSD | arylsulfatase D | -0.76 |
| TMEM14C | transmembrane protein 14C | -0.66 |
| ANKS6 | ankyrin repeat and sterile alpha motif domain containing 6 | -0.62 |
| APOB | apolipoprotein B | -0.52 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | -0.51 |
| NADSYN1 | NAD synthetase 1 | -0.51 |
| TMC4 | transmembrane channel-like 4 | -0.51 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.5 |
| FAM241B | family with sequence similarity 241 member B | -0.5 |
| DNAH9 | dynein, axonemal, heavy chain 9 | -0.49 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.48 |
| TUBAL3 | tubulin, alpha-like 3 | -0.48 |
| H1-0 | H1.0 linker histone | -0.48 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | -0.48 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.46 |
| CD63 | CD63 molecule | -0.46 |
| STARD3NL | STARD3 N-terminal like | -0.46 |
| HMOX1 | heme oxygenase 1 | -0.45 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.45 |
| ADCY5 | adenylate cyclase 5 | -0.45 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 | -0.44 |
| MBP | myelin basic protein | -0.43 |
| APOLTP | apolipoprotein lipid transfer particle homolog | -0.43 |
| SLC45A4 | solute carrier family 45, member 4 | -0.42 |
| NCOA4 | nuclear receptor coactivator 4 | -0.42 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.42 |
| SLC30A6 | solute carrier family 30 (zinc transporter), member 6 | -0.42 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.41 |
| HFE | hemochromatosis | -0.41 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 | -0.38 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | -0.37 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.37 |
| LIPH | lipase, member H | -0.36 |
| FAM124A | family with sequence similarity 124A | -0.36 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.36 |
| MCFD2 | multiple coagulation factor deficiency 2 | -0.36 |
| HMGN4 | high mobility group nucleosomal binding domain 4 | -0.36 |
| TMC6 | transmembrane channel-like 6 | -0.36 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.35 |
| ZNF444 | zinc finger protein 444 | -0.35 |
| TYMP | thymidine phosphorylase | -0.35 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -0.35 |
| CHRD | chordin | -0.35 |
| ZBTB41 | zinc finger and BTB domain containing 41 | -0.34 |
| MARCKSL1 | MARCKS-like 1 | -0.34 |
| TCP11L1 | t-complex 11, testis-specific-like 1 | -0.34 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.33 |
| CHMP4C | charged multivesicular body protein 4C | -0.33 |
| RAB19 | RAB19, member RAS oncogene family | -0.33 |
| ST7 | suppression of tumorigenicity 7 | -0.33 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.33 |
| ZNF189 | zinc finger protein 189 | -0.33 |
| CCN3 | cellular communication network factor 3 | -0.33 |
| FTL | ferritin, light polypeptide | -0.32 |
| TSN | translin | -0.32 |
| WHAMM | WAS protein homolog associated with actin, golgi membranes and microtubules | -0.32 |
| SKIL | SKI-like proto-oncogene | -0.32 |
| PRNP | prion protein | -0.32 |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) | -0.32 |
| LRP6 | low density lipoprotein receptor-related protein 6 | -0.32 |
| C15ORF61 | chromosome 15 open reading frame 61 | -0.32 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 | -0.31 |
| FAS | Fas cell surface death receptor | -0.31 |
| RGS20 | regulator of G-protein signaling 20 | -0.31 |
| ETAA1 | Ewing tumor-associated antigen 1 | -0.31 |
| GPN2 | GPN-loop GTPase 2 | -0.31 |
| PRKX | protein kinase, X-linked | -0.31 |
| CRTC3 | CREB regulated transcription coactivator 3 | -0.31 |
| CALHM2 | calcium homeostasis modulator 2 | -0.31 |
| LMBRD1 | LMBR1 domain containing 1 | -0.31 |
| TTC30B | tetratricopeptide repeat domain 30B | -0.31 |
| CSNK1A1L | casein kinase 1, alpha 1-like | -0.31 |
| TMEM135 | transmembrane protein 135 | -0.3 |
| MYO1G | myosin IG | -0.3 |
| KIAA0513 | KIAA0513 | -0.3 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | -0.3 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.3 |
| BBS7 | Bardet-Biedl syndrome 7 | -0.3 |
| ZNF286B | zinc finger protein 286B | -0.3 |
| WDR90 | WD repeat domain 90 | -0.3 |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta | -0.3 |
| MIB2 | mindbomb E3 ubiquitin protein ligase 2 | -0.29 |
| KIAA1217 | KIAA1217 | -0.29 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.29 |
| RAP2A | RAP2A, member of RAS oncogene family | -0.29 |
| S100A14 | S100 calcium binding protein A14 | -0.28 |
| LAMA3 | laminin, alpha 3 | -0.28 |
| ARL8A | ADP-ribosylation factor-like 8A | -0.28 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.28 |
| UBL3 | ubiquitin-like 3 | -0.28 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.28 |
| MID1IP1 | MID1 interacting protein 1 | -0.28 |
