Acanthosis Nigricans Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_3138)
External Link https://www.disgenet.org/browser/0/1/0/C0000889
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Genes

64 genes associated with the disease Acanthosis Nigricans in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AIP aryl hydrocarbon receptor interacting protein
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALMS1 Alstrom syndrome protein 1
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CAV1 caveolin 1, caveolae protein, 22kDa
CAVIN1 caveolae associated protein 1
CIDEC cell death-inducing DFFA-like effector c
CLDN1 claudin 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRP C-reactive protein, pentraxin-related
CUL4B cullin 4B
CXCL8 chemokine (C-X-C motif) ligand 8
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
ELOVL1 ELOVL fatty acid elongase 1
ERF Ets2 repressor factor
ESR1 estrogen receptor 1
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FOS FBJ murine osteosarcoma viral oncogene homolog
GPR101 G protein-coupled receptor 101
GRAP2 GRB2-related adaptor protein 2
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HRAS Harvey rat sarcoma viral oncogene homolog
IGF1R insulin-like growth factor 1 receptor
IL6 interleukin 6
INS insulin
INSR insulin receptor
JUP junction plakoglobin
KDR kinase insert domain receptor
KRT18 keratin 18, type I
LEP leptin
LIPE lipase, hormone-sensitive
LMNA lamin A/C
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MC4R melanocortin 4 receptor
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae)
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
PCNA proliferating cell nuclear antigen
PCSK1 proprotein convertase subtilisin/kexin type 1
PEX1 peroxisomal biogenesis factor 1
PEX6 peroxisomal biogenesis factor 6
PLIN1 perilipin 1
PNPLA2 patatin-like phospholipase domain containing 2
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POMC proopiomelanocortin
PPARG peroxisome proliferator-activated receptor gamma
PRMT7 protein arginine methyltransferase 7
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SPINK5 serine peptidase inhibitor, Kazal type 5
TBC1D4 TBC1 domain family, member 4
TGFA transforming growth factor, alpha
TNF tumor necrosis factor
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZMPSTE24 zinc metallopeptidase STE24