Aceruloplasminemia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description An iron metabolism disease that has_material_basis_in a mutation in the ceruloplasmin gene characterized by progressive neurodegeneration of the retina and basal ganglia and diabetes mellitus. (Human Disease Ontology, DOID_0050711)
Similar Terms
Downloads & Tools

Genes

129 genes co-occuring with the disease Aceruloplasminemia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CP ceruloplasmin (ferroxidase) 3.008
PANK2 pantothenate kinase 2 2.961
TFR2 transferrin receptor 2 2.743
HFE hemochromatosis 2.74
HAMP hepcidin antimicrobial peptide 2.709
HJV hemojuvelin BMP co-receptor 2.679
FTL ferritin, light polypeptide 2.669
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 2.655
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 2.651
COASY CoA synthase 2.599
ATP7B ATPase, Cu++ transporting, beta polypeptide 2.58
C19ORF12 chromosome 19 open reading frame 12 2.58
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 2.556
FA2H fatty acid 2-hydroxylase 2.49
DCAF17 DDB1 and CUL4 associated factor 17 2.477
CYBRD1 cytochrome b reductase 1 2.42
WDR45 WD repeat domain 45 2.336
TFRC transferrin receptor 2.315
ATP13A2 ATPase type 13A2 2.309
IREB2 iron-responsive element binding protein 2 2.286
FXN frataxin 2.25
PANK1 pantothenate kinase 1 2.214
ACO1 aconitase 1, soluble 2.195
ATOX1 antioxidant 1 copper chaperone 2.124
SLC39A14 solute carrier family 39 (zinc transporter), member 14 2.106
STEAP3 STEAP family member 3, metalloreductase 2.097
FTH1 ferritin, heavy polypeptide 1 1.934
ATP7A ATPase, Cu++ transporting, alpha polypeptide 1.877
BMP6 bone morphogenetic protein 6 1.874
TMPRSS6 transmembrane protease, serine 6 1.858
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 1.852
STEAP1 six transmembrane epithelial antigen of the prostate 1 1.801
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.797
GTPBP2 GTP binding protein 2 1.796
REPS1 RALBP1 associated Eps domain containing 1 1.783
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 1.782
COX17 COX17 cytochrome c oxidase copper chaperone 1.757
HEPH hephaestin 1.726
CCS copper chaperone for superoxide dismutase 1.718
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 1.717
SLC46A1 solute carrier family 46 (folate transporter), member 1 1.706
STEAP2 STEAP family member 2, metalloreductase 1.7
FTMT ferritin mitochondrial 1.671
APP amyloid beta (A4) precursor protein 1.635
HPX hemopexin 1.626
SLC39A8 solute carrier family 39 (zinc transporter), member 8 1.624
LIX1 Lix1 homolog (chicken) 1.615
MT1E metallothionein 1E 1.612
DNAH8 dynein, axonemal, heavy chain 8 1.605
COMMD1 copper metabolism (Murr1) domain containing 1 1.588
PCBP1 poly(rC) binding protein 1 1.579
CCDC115 coiled-coil domain containing 115 1.551
CPOX coproporphyrinogen oxidase 1.538
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 1.531
PANK3 pantothenate kinase 3 1.504
ACO2 aconitase 2, mitochondrial 1.498
PAM peptidylglycine alpha-amidating monooxygenase 1.484
ALAS2 5'-aminolevulinate synthase 2 1.481
FBXL5 F-box and leucine-rich repeat protein 5 1.48
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 1.464
RPE65 retinal pigment epithelium-specific protein 65kDa 1.451
HMOX1 heme oxygenase 1 1.401
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 1.395
A2M alpha-2-macroglobulin 1.385
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 1.38
SLC31A1 solute carrier family 31 (copper transporter), member 1 1.379
NCOA4 nuclear receptor coactivator 4 1.377
SCARA5 scavenger receptor class A, member 5 1.376
MB myoglobin 1.365
FECH ferrochelatase 1.31
AP4M1 adaptor-related protein complex 4, mu 1 subunit 1.308
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1.301
DIPK1A divergent protein kinase domain 1A 1.296
HP haptoglobin 1.289
LYRM4 LYR motif containing 4 1.287
LTF lactotransferrin 1.283
ALB albumin 1.281
GPX4 glutathione peroxidase 4 1.276
SOD1 superoxide dismutase 1, soluble 1.262
ISCU iron-sulfur cluster assembly enzyme 1.258
GPX6 glutathione peroxidase 6 1.25
PRDX3 peroxiredoxin 3 1.246
JPH3 junctophilin 3 1.242
ERFE erythroferrone 1.239
CGNL1 cingulin-like 1 1.229
TH tyrosine hydroxylase 1.223
PNKD paroxysmal nonkinesigenic dyskinesia 1.223
RGMB repulsive guidance molecule family member b 1.221
COX11 COX11 cytochrome c oxidase copper chaperone 1.214
SLC31A2 solute carrier family 31 (copper transporter), member 2 1.21
GPX5 glutathione peroxidase 5 1.208
TMEM199 transmembrane protein 199 1.2
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 1.191
TYR tyrosinase 1.191
GPX8 glutathione peroxidase 8 (putative) 1.186
GPX3 glutathione peroxidase 3 1.186
GPX7 glutathione peroxidase 7 1.183
PARK7 parkinson protein 7 1.182
PANK4 pantothenate kinase 4 1.181
GPX2 glutathione peroxidase 2 1.174
NPC1 Niemann-Pick disease, type C1 1.16
SCO1 SCO1 cytochrome c oxidase assembly protein 1.158
EPO erythropoietin 1.156
ALG6 ALG6, alpha-1,3-glucosyltransferase 1.149
EPAS1 endothelial PAS domain protein 1 1.131
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 1.125
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.115
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 1.113
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.108
HTT huntingtin 1.106
GLRX5 glutaredoxin 5 1.102
AAMP angio-associated, migratory cell protein 1.093
INSL4 insulin-like 4 (placenta) 1.092
NPC2 Niemann-Pick disease, type C2 1.087
FRRS1L ferric-chelate reductase 1-like 1.081
IL6 interleukin 6 1.071
PRNP prion protein 1.07
DPYSL5 dihydropyrimidinase-like 5 1.069
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 1.058
PINK1 PTEN induced putative kinase 1 1.045
LOX lysyl oxidase 1.043
APOE apolipoprotein E 1.034
FDX2 ferredoxin 2 1.031
CRAT carnitine O-acetyltransferase 1.027
SFXN1 sideroflexin 1 1.024
NAGA N-acetylgalactosaminidase, alpha- 1.014
ATN1 atrophin 1 1.005
PCBP2 poly(rC) binding protein 2 1.004
KCP kielin/chordin-like protein 1.0