| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetazolamide perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Acetazolamide_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.15573 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.15165 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0903492 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0669116 |
| OGA | O-GlcNAcase | 0.060605 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0580601 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0517632 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0502691 |
| SETD5 | SET domain containing 5 | 0.0484044 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0461789 |
| FAM107B | family with sequence similarity 107, member B | 0.0435823 |
| INSIG2 | insulin induced gene 2 | 0.042591 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.041552 |
| COPA | coatomer protein complex, subunit alpha | 0.0415268 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0401243 |
| OPTN | optineurin | 0.0392922 |
| GOLGA4 | golgin A4 | 0.0385772 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0339054 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0332823 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0327408 |
| CD109 | CD109 molecule | 0.0323673 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0323623 |
| MXI1 | MAX interactor 1, dimerization protein | 0.03231 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0313734 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0297321 |
| ATP13A3 | ATPase type 13A3 | 0.0295815 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0292859 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.0291406 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0287865 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0283232 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0283135 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | 0.0282506 |
| AFDN | afadin, adherens junction formation factor | 0.0282464 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0282359 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0280745 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0280109 |
| PTMA | prothymosin, alpha | 0.027742 |
| STC1 | stanniocalcin 1 | 0.0269727 |
| MMP12 | matrix metallopeptidase 12 | 0.0269144 |
| MSN | moesin | 0.0267469 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.026403 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0263937 |
| C1ORF21 | chromosome 1 open reading frame 21 | 0.026126 |
| HELZ | helicase with zinc finger | 0.0261126 |
| HIP1 | huntingtin interacting protein 1 | 0.0258429 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0255998 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0253055 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0248019 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0244379 |
| ZNF654 | zinc finger protein 654 | 0.0239438 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0239434 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0238294 |
| SNX9 | sorting nexin 9 | 0.0236627 |
| FNBP1L | formin binding protein 1-like | 0.022953 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0229525 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0227606 |
| SBF2 | SET binding factor 2 | 0.0227005 |
| MYOF | myoferlin | 0.022454 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | 0.0224514 |
| ADM | adrenomedullin | 0.0224128 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0222934 |
| RAB18 | RAB18, member RAS oncogene family | 0.0222078 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0221715 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0220874 |
| CSTB | cystatin B (stefin B) | 0.0220387 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0219261 |
| TFG | TRK-fused gene | 0.0219256 |
| DTNA | dystrobrevin, alpha | 0.0217561 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0217164 |
| RNF24 | ring finger protein 24 | 0.0217135 |
| QKI | QKI, KH domain containing, RNA binding | 0.0216336 |
| SUCO | SUN domain containing ossification factor | 0.0214938 |
| DIAPH1 | diaphanous-related formin 1 | 0.0212092 |
| UBC | ubiquitin C | 0.0211551 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0210828 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0209033 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0208615 |
| BCAP31 | B-cell receptor-associated protein 31 | 0.020714 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0206815 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0205713 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0205684 |
| C1D | C1D nuclear receptor corepressor | 0.0201772 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0201484 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0201071 |
| MEF2A | myocyte enhancer factor 2A | 0.0199856 |
| NGLY1 | N-glycanase 1 | 0.0198726 |
| CDK18 | cyclin-dependent kinase 18 | 0.0197533 |
| RAI1 | retinoic acid induced 1 | 0.0195609 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0194359 |
| ERBIN | erbb2 interacting protein | 0.0192987 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0192751 |
| ABI1 | abl-interactor 1 | 0.0192226 |
| ITSN2 | intersectin 2 | 0.0191459 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0191298 |
| RAB10 | RAB10, member RAS oncogene family | 0.0191174 |
| KIF13A | kinesin family member 13A | 0.018909 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0187545 |
| CTBP2 | C-terminal binding protein 2 | 0.0187225 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0187176 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0187169 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.223844 |
| NAV1 | neuron navigator 1 | -0.158651 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.146999 |
| TMSB10 | thymosin beta 10 | -0.138562 |
| AHNAK | AHNAK nucleoprotein | -0.0946238 |
| PODXL | podocalyxin-like | -0.0897609 |
| LOX | lysyl oxidase | -0.0897016 |
| MAP1B | microtubule-associated protein 1B | -0.0892728 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0886127 |
| MX2 | MX dynamin-like GTPase 2 | -0.0825603 |
| CD44 | CD44 molecule (Indian blood group) | -0.0752385 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0740364 |
| COL5A1 | collagen, type V, alpha 1 | -0.0739033 |
| S100A10 | S100 calcium binding protein A10 | -0.0712702 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0704896 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0694778 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0672864 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0649241 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0642574 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0634287 |
| MEIS2 | Meis homeobox 2 | -0.0627058 |
| RIGI | RNA sensor RIG-I | -0.0609985 |
| HLA-B | major histocompatibility complex, class I, B | -0.0606846 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0593022 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0537202 |
| SUCNR1 | succinate receptor 1 | -0.0526219 |
| GLIS3 | GLIS family zinc finger 3 | -0.0523003 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0521243 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0487421 |
| CDH13 | cadherin 13 | -0.0481105 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0479693 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0476059 |
| HLA-C | major histocompatibility complex, class I, C | -0.0475452 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0474705 |
| RNF213 | ring finger protein 213 | -0.0457792 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0453938 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0439683 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.041995 |
| COL1A2 | collagen, type I, alpha 2 | -0.0412764 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.039379 |
| THBS2 | thrombospondin 2 | -0.0385569 |
| LMNA | lamin A/C | -0.0385409 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0373437 |
| PRSS23 | protease, serine, 23 | -0.0368417 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0366435 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.03574 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0350244 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0350055 |
| CUX1 | cut-like homeobox 1 | -0.0348071 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0346997 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0342397 |
| NDRG1 | N-myc downstream regulated 1 | -0.0332607 |
| PXDN | peroxidasin | -0.0329654 |
| EFNA5 | ephrin-A5 | -0.0327826 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0326789 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0324964 |
| ACTG1 | actin gamma 1 | -0.0324886 |
| ANXA2 | annexin A2 | -0.032357 |
| TPM1 | tropomyosin 1 (alpha) | -0.0323443 |
| LOXL2 | lysyl oxidase-like 2 | -0.0322432 |
| CALR | calreticulin | -0.0315531 |
| FRMD4A | FERM domain containing 4A | -0.0314821 |
| COL3A1 | collagen, type III, alpha 1 | -0.0310832 |
| FUS | FUS RNA binding protein | -0.0310236 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0309192 |
| SMYD3 | SET and MYND domain containing 3 | -0.0305188 |
| TUBB | tubulin, beta class I | -0.0304596 |
| CCND1 | cyclin D1 | -0.0304421 |
| CDK6 | cyclin-dependent kinase 6 | -0.0300671 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0297057 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0295773 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0293659 |
| NPR2 | natriuretic peptide receptor 2 | -0.0292029 |
| RRBP1 | ribosome binding protein 1 | -0.0278085 |
| ACTN4 | actinin, alpha 4 | -0.0276323 |
| EHBP1 | EH domain binding protein 1 | -0.0276089 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0274655 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0272398 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0272235 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0268806 |
| PLXNA2 | plexin A2 | -0.0268757 |
| COL5A2 | collagen, type V, alpha 2 | -0.0268634 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0262647 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0262178 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0261131 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.025843 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0256703 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0256081 |
| ARF1 | ADP-ribosylation factor 1 | -0.0254319 |
| OSMR | oncostatin M receptor | -0.0252611 |
| SP100 | SP100 nuclear antigen | -0.0252517 |
| BSG | basigin (Ok blood group) | -0.0249115 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0248011 |
| GSE1 | Gse1 coiled-coil protein | -0.0247045 |
| CEP112 | centrosomal protein 112kDa | -0.024313 |
| S100A4 | S100 calcium binding protein A4 | -0.0242708 |
| RAD51B | RAD51 paralog B | -0.0241538 |
| RPS24 | ribosomal protein S24 | -0.0241379 |
| CAVIN1 | caveolae associated protein 1 | -0.024123 |
| FSTL1 | follistatin-like 1 | -0.0241149 |
