| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetazolamide perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Acetazolamide_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.177398 |
| AREG | amphiregulin | 0.0872039 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0587375 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0468582 |
| ANXA1 | annexin A1 | 0.0455517 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0445683 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0427549 |
| CPOX | coproporphyrinogen oxidase | 0.0411211 |
| KIF5B | kinesin family member 5B | 0.040937 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0395289 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.039173 |
| MATR3 | matrin 3 | 0.0380558 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0364845 |
| ECT2 | epithelial cell transforming 2 | 0.0347998 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0330264 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0323141 |
| CCNL1 | cyclin L1 | 0.0321986 |
| KLHL24 | kelch-like family member 24 | 0.0305407 |
| TMEM41B | transmembrane protein 41B | 0.0305106 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0297855 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0292325 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0282264 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0278645 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0268576 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0267957 |
| COPA | coatomer protein complex, subunit alpha | 0.0263954 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0263095 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0248704 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0248284 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0244193 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0243602 |
| THOC1 | THO complex 1 | 0.0243501 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0243246 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0241595 |
| TBK1 | TANK-binding kinase 1 | 0.0237583 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0234519 |
| VMP1 | vacuole membrane protein 1 | 0.0232745 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0232335 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0225546 |
| OGA | O-GlcNAcase | 0.0224473 |
| THOC2 | THO complex 2 | 0.0223832 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0220698 |
| ENO1 | enolase 1, (alpha) | 0.021858 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.021771 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0217252 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0216044 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0214817 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0212378 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0210349 |
| NEK7 | NIMA-related kinase 7 | 0.0205739 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0205302 |
| TNPO1 | transportin 1 | 0.0203377 |
| FAM162A | family with sequence similarity 162, member A | 0.0202643 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0202039 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0201644 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0200839 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0200413 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0200285 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0198838 |
| WDR45B | WD repeat domain 45B | 0.0196908 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0194993 |
| GASK1B | golgi associated kinase 1B | 0.019413 |
| TSNAX | translin-associated factor X | 0.0194051 |
| EPHA6 | EPH receptor A6 | 0.0192914 |
| USP53 | ubiquitin specific peptidase 53 | 0.0190981 |
| CASC3 | cancer susceptibility candidate 3 | 0.0190952 |
| ARRDC3 | arrestin domain containing 3 | 0.0188469 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.018596 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0185441 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0184199 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0184103 |
| PLK2 | polo-like kinase 2 | 0.0184039 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0183002 |
| SSRP1 | structure specific recognition protein 1 | 0.0180608 |
| VIM | vimentin | 0.0178524 |
| PNN | pinin, desmosome associated protein | 0.017727 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0176459 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0175481 |
| PTMA | prothymosin, alpha | 0.0174436 |
| PCBP2 | poly(rC) binding protein 2 | 0.0173618 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.01719 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0171879 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0170932 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0169519 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0169208 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0168325 |
| OXR1 | oxidation resistance 1 | 0.016818 |
| SUCO | SUN domain containing ossification factor | 0.0166538 |
| FAM13B | family with sequence similarity 13, member B | 0.0166477 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0166467 |
| SET | SET nuclear proto-oncogene | 0.016618 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0165324 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0163858 |
| TMED4 | transmembrane emp24 protein transport domain containing 4 | 0.0163675 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0162711 |
| NUP58 | nucleoporin 58 | 0.0162204 |
| PTCD3 | pentatricopeptide repeat domain 3 | 0.0161802 |
| CRY1 | cryptochrome circadian clock 1 | 0.0159772 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0159364 |
| LEMD3 | LEM domain containing 3 | 0.0158722 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | -0.329418 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.316269 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.176239 |
| PCDH7 | protocadherin 7 | -0.1371 |
| TMSB10 | thymosin beta 10 | -0.127815 |
| HMGA2 | high mobility group AT-hook 2 | -0.121593 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.100662 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0905499 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0844692 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0730775 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.069866 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0648462 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0638342 |
| NHSL1 | NHS-like 1 | -0.0615937 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0611132 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0611071 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0590087 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.05771 |
| EHBP1 | EH domain binding protein 1 | -0.057507 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0549991 |
| ZNF804A | zinc finger protein 804A | -0.054564 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.05277 |
| RASAL2 | RAS protein activator like 2 | -0.0522685 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0520459 |
| PDGFC | platelet derived growth factor C | -0.0501219 |
| ACTG1 | actin gamma 1 | -0.0495598 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0486665 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.048039 |
| TENM3 | teneurin transmembrane protein 3 | -0.0467665 |
| DST | dystonin | -0.0446801 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0429713 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0427331 |
| CMIP | c-Maf inducing protein | -0.0426969 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0423844 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0421868 |
| YAP1 | Yes-associated protein 1 | -0.0419572 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0418402 |
| PCDH9 | protocadherin 9 | -0.0417287 |
| NABP1 | nucleic acid binding protein 1 | -0.0409948 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0402734 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0399115 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0393254 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0392301 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0385009 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0380569 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0378373 |
| EGR1 | early growth response 1 | -0.037726 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.037324 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0359469 |
| NEBL | nebulette | -0.0359327 |
| HMGA1 | high mobility group AT-hook 1 | -0.0358674 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0354986 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0354095 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0353925 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0351027 |
| EXOC4 | exocyst complex component 4 | -0.034916 |
| INTS6 | integrator complex subunit 6 | -0.0348356 |
| RPLP1 | ribosomal protein, large, P1 | -0.0347139 |
| MMP12 | matrix metallopeptidase 12 | -0.0346187 |
| CEP112 | centrosomal protein 112kDa | -0.0342066 |
| AHNAK | AHNAK nucleoprotein | -0.0336414 |
| NEGR1 | neuronal growth regulator 1 | -0.033516 |
| CUX1 | cut-like homeobox 1 | -0.0333594 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.033164 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0329008 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0328066 |
| EXOC6B | exocyst complex component 6B | -0.0319646 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0319226 |
| RPL35A | ribosomal protein L35a | -0.0317244 |
| RPL19 | ribosomal protein L19 | -0.031696 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0316252 |
| THSD7A | thrombospondin, type I, domain containing 7A | -0.031417 |
| CCND1 | cyclin D1 | -0.0314104 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0310496 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0305874 |
| RPS19 | ribosomal protein S19 | -0.0303955 |
| NRXN3 | neurexin 3 | -0.0295076 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0283574 |
| EDARADD | EDAR-associated death domain | -0.0283045 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0282612 |
| JMJD1C | jumonji domain containing 1C | -0.0279302 |
| ZNF638 | zinc finger protein 638 | -0.0279102 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0277666 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0276586 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0275553 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0275359 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0275028 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0274106 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0272989 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0271922 |
| PRKCE | protein kinase C, epsilon | -0.0269743 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0266016 |
| RPL36 | ribosomal protein L36 | -0.0265115 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.026436 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0264286 |
| RPS29 | ribosomal protein S29 | -0.0255456 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0254727 |
| FTL | ferritin, light polypeptide | -0.0254096 |
| PHF14 | PHD finger protein 14 | -0.0253273 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0250938 |
