| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetazolamide perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Acetazolamide_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNIP | thioredoxin interacting protein | 0.097418 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0957904 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0825967 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0804771 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0765345 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0744819 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0705743 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0661008 |
| PLSCR2 | phospholipid scramblase 2 | 0.0630999 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0628409 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0611931 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0606412 |
| PRKCA | protein kinase C, alpha | 0.0590095 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0577268 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0554528 |
| PGK1 | phosphoglycerate kinase 1 | 0.0554137 |
| INTS6 | integrator complex subunit 6 | 0.0508123 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0486988 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0483145 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0464616 |
| RNF149 | ring finger protein 149 | 0.0461439 |
| ASPH | aspartate beta-hydroxylase | 0.0447281 |
| LIMA1 | LIM domain and actin binding 1 | 0.0446648 |
| FAT1 | FAT atypical cadherin 1 | 0.044255 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0429479 |
| ENO1 | enolase 1, (alpha) | 0.0427311 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.042326 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0413872 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0412745 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0412368 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0405247 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0398189 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0396803 |
| USP34 | ubiquitin specific peptidase 34 | 0.0389419 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0387312 |
| DENND4C | DENN/MADD domain containing 4C | 0.0383141 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0378293 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0377935 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.037774 |
| APOL1 | apolipoprotein L, 1 | 0.0368076 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0364664 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0364042 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0357609 |
| PHF3 | PHD finger protein 3 | 0.035325 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0352006 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0339986 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0334528 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0333291 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.032612 |
| AREG | amphiregulin | 0.0322961 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0321214 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0319624 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0306953 |
| EFNB2 | ephrin-B2 | 0.0304781 |
| EPCAM | epithelial cell adhesion molecule | 0.0304295 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0302591 |
| OGA | O-GlcNAcase | 0.0298272 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0298026 |
| IFNGR1 | interferon gamma receptor 1 | 0.0297251 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0296807 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0290567 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0285562 |
| DENND1A | DENN/MADD domain containing 1A | 0.0284278 |
| PTGR1 | prostaglandin reductase 1 | 0.0278942 |
| PTK2 | protein tyrosine kinase 2 | 0.0278381 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0274642 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0271098 |
| PDS5B | PDS5 cohesin associated factor B | 0.0268082 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0267238 |
| PAPOLA | poly(A) polymerase alpha | 0.02641 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0262055 |
| TBPL1 | TBP-like 1 | 0.026204 |
| PRELID2 | PRELI domain containing 2 | 0.0260844 |
| PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta | 0.0260792 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.0260722 |
| CDC42SE2 | CDC42 small effector 2 | 0.0260128 |
| STK39 | serine threonine kinase 39 | 0.0259335 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0257793 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.025705 |
| MEIS2 | Meis homeobox 2 | 0.0256109 |
| EREG | epiregulin | 0.0249527 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0248956 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0248147 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0247222 |
| KIF16B | kinesin family member 16B | 0.0243772 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0241802 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0240923 |
| MATR3 | matrin 3 | 0.0239583 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0239317 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0239266 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0239003 |
| MLPH | melanophilin | 0.0238867 |
| EHF | ets homologous factor | 0.0238646 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0238301 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.023776 |
| BBX | bobby sox homolog (Drosophila) | 0.0236882 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0233704 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0231862 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.022923 |
| USP53 | ubiquitin specific peptidase 53 | 0.0228481 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.192109 |
| EGR1 | early growth response 1 | -0.116306 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0986518 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0959444 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0899643 |
| SPATA13 | spermatogenesis associated 13 | -0.0699377 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0652078 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0623954 |
| B2M | beta-2-microglobulin | -0.0623433 |
| EZR | ezrin | -0.0567689 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0558419 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0556449 |
| MX1 | MX dynamin-like GTPase 1 | -0.0533201 |
| PLSCR1 | phospholipid scramblase 1 | -0.0519801 |
| MX2 | MX dynamin-like GTPase 2 | -0.0497562 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0476905 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.046537 |
| RUNX1 | runt-related transcription factor 1 | -0.0445581 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0443055 |
| EPHB2 | EPH receptor B2 | -0.0436259 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0418342 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0417133 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0416931 |
| IRF1 | interferon regulatory factor 1 | -0.0412397 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0406911 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0405706 |
| FNIP2 | folliculin interacting protein 2 | -0.040548 |
| NDRG1 | N-myc downstream regulated 1 | -0.0394569 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0384428 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0381845 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0380918 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0377546 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0376667 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0368993 |
| FOXP1 | forkhead box P1 | -0.0366165 |
| NF1 | neurofibromin 1 | -0.0362284 |
| HM13 | histocompatibility (minor) 13 | -0.0352861 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | -0.0349901 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0345478 |
| COG6 | component of oligomeric golgi complex 6 | -0.0344419 |
| ANXA1 | annexin A1 | -0.0333718 |
| KIAA1217 | KIAA1217 | -0.0330826 |
| GOLGB1 | golgin B1 | -0.0326789 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | -0.0321516 |
| RIGI | RNA sensor RIG-I | -0.0318959 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0316134 |
| PMP22 | peripheral myelin protein 22 | -0.0314755 |
| YBX3 | Y box binding protein 3 | -0.0310639 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0305018 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0302172 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0301723 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0298478 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0296982 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0295495 |
| TC2N | tandem C2 domains, nuclear | -0.0290787 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0290147 |
| ITGA6 | integrin, alpha 6 | -0.0288707 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0288408 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0287246 |
| ZNF207 | zinc finger protein 207 | -0.0282831 |
| RBM47 | RNA binding motif protein 47 | -0.0278136 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0274964 |
| RRBP1 | ribosome binding protein 1 | -0.0274352 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0272364 |
| CCNL1 | cyclin L1 | -0.027155 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0271109 |
| BPTF | bromodomain PHD finger transcription factor | -0.0269793 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0269672 |
| CENPF | centromere protein F, 350/400kDa | -0.0268756 |
| TPR | translocated promoter region, nuclear basket protein | -0.0267716 |
| GOSR2 | golgi SNAP receptor complex member 2 | -0.0267384 |
| DIAPH3 | diaphanous-related formin 3 | -0.0267379 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0266303 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0264601 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0263548 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0261283 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.02595 |
| ATP11A | ATPase, class VI, type 11A | -0.025797 |
| SYT1 | synaptotagmin I | -0.0256916 |
| CALU | calumenin | -0.0256114 |
| TRIM2 | tripartite motif containing 2 | -0.0252772 |
| JUN | jun proto-oncogene | -0.0251704 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0250443 |
| SERINC5 | serine incorporator 5 | -0.0246719 |
| BRCA2 | breast cancer 2, early onset | -0.0239664 |
| CALR | calreticulin | -0.0238457 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0234385 |
| MKI67 | marker of proliferation Ki-67 | -0.0233688 |
| HLA-C | major histocompatibility complex, class I, C | -0.0233206 |
| ATM | ATM serine/threonine kinase | -0.0232993 |
| HLA-A | major histocompatibility complex, class I, A | -0.0232801 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.023142 |
| TNS4 | tensin 4 | -0.0231346 |
| AGR2 | anterior gradient 2 | -0.0229901 |
| FUBP3 | far upstream element (FUSE) binding protein 3 | -0.0228887 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0227924 |
| ERBIN | erbb2 interacting protein | -0.0226598 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0224514 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0223967 |
| RAB10 | RAB10, member RAS oncogene family | -0.0223569 |
