| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetazolamide perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Acetazolamide_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.120534 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.11427 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0789307 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0717613 |
| ATP13A3 | ATPase type 13A3 | 0.063311 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0615975 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0477508 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0453883 |
| COL1A2 | collagen, type I, alpha 2 | 0.0447308 |
| GOLGA4 | golgin A4 | 0.0382187 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.037538 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0358756 |
| POSTN | periostin, osteoblast specific factor | 0.0352283 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0334033 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0319464 |
| ADM | adrenomedullin | 0.0319041 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0283688 |
| VEGFA | vascular endothelial growth factor A | 0.0276115 |
| SPAG9 | sperm associated antigen 9 | 0.0275935 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0274755 |
| ARRDC3 | arrestin domain containing 3 | 0.0260244 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0259868 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0259793 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0246722 |
| DSTN | destrin (actin depolymerizing factor) | 0.0246501 |
| SUCO | SUN domain containing ossification factor | 0.0243173 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0242047 |
| MSN | moesin | 0.0241188 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0240563 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0226833 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0225177 |
| TMF1 | TATA element modulatory factor 1 | 0.0223593 |
| TFG | TRK-fused gene | 0.0220346 |
| MATR3 | matrin 3 | 0.0216776 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0216765 |
| RAB6A | RAB6A, member RAS oncogene family | 0.021485 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0211269 |
| SQLE | squalene epoxidase | 0.0210126 |
| SETD5 | SET domain containing 5 | 0.0209934 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0208481 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0205981 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.02051 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0204921 |
| MRTFA | myocardin related transcription factor A | 0.0203737 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0202015 |
| NOP58 | NOP58 ribonucleoprotein | 0.0201996 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0197165 |
| MTSS1 | metastasis suppressor 1 | 0.0196732 |
| XPO1 | exportin 1 | 0.0194241 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0193607 |
| DCAF13 | DDB1 and CUL4 associated factor 13 | 0.0193187 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0192958 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0191326 |
| RPL3 | ribosomal protein L3 | 0.0187651 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.018702 |
| PCBP2 | poly(rC) binding protein 2 | 0.0185815 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0184659 |
| HELZ | helicase with zinc finger | 0.0183779 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0183443 |
| RYBP | RING1 and YY1 binding protein | 0.0183248 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.018304 |
| COPA | coatomer protein complex, subunit alpha | 0.0178622 |
| USP3 | ubiquitin specific peptidase 3 | 0.0178466 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0174678 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0172672 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0172406 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0172015 |
| CD109 | CD109 molecule | 0.0171455 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0171066 |
| BRD2 | bromodomain containing 2 | 0.0169981 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0166213 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.016512 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0163274 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0163145 |
| RIOK3 | RIO kinase 3 | 0.0162903 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0162534 |
| SET | SET nuclear proto-oncogene | 0.0161715 |
| NUP58 | nucleoporin 58 | 0.0161403 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0161336 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0157954 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0156968 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0156787 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0154191 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0153945 |
| PDE10A | phosphodiesterase 10A | 0.0153392 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0151565 |
| NUP153 | nucleoporin 153kDa | 0.0150602 |
| MYO10 | myosin X | 0.0150029 |
| APP | amyloid beta (A4) precursor protein | 0.0148098 |
| PDS5B | PDS5 cohesin associated factor B | 0.0146889 |
| FBXO7 | F-box protein 7 | 0.0146519 |
| RNF145 | ring finger protein 145 | 0.0145068 |
| DIAPH1 | diaphanous-related formin 1 | 0.0145036 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0142808 |
| OGA | O-GlcNAcase | 0.0142768 |
| ANXA5 | annexin A5 | 0.0141993 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0141868 |
| FNBP1L | formin binding protein 1-like | 0.0141318 |
| SNX3 | sorting nexin 3 | 0.0141072 |
| AZIN1 | antizyme inhibitor 1 | 0.013999 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH13 | cadherin 13 | -0.107922 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.106813 |
| COL1A1 | collagen, type I, alpha 1 | -0.0969241 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0936888 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0900743 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0893107 |
| TMSB10 | thymosin beta 10 | -0.0772018 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0758246 |
| VIM | vimentin | -0.0717768 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.068801 |
| ASPH | aspartate beta-hydroxylase | -0.0679683 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0663623 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0646906 |
| RPL35A | ribosomal protein L35a | -0.0643194 |
| HMGA2 | high mobility group AT-hook 2 | -0.0552808 |
| IER3 | immediate early response 3 | -0.0540777 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0530539 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0529145 |
| GLIS3 | GLIS family zinc finger 3 | -0.0510712 |
| CNTN5 | contactin 5 | -0.0506906 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0506432 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0500284 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0484637 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0474681 |
| RPS8 | ribosomal protein S8 | -0.0458742 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0456041 |
| ATXN1 | ataxin 1 | -0.0447032 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.041721 |
| CD44 | CD44 molecule (Indian blood group) | -0.0402012 |
| AHNAK | AHNAK nucleoprotein | -0.0398961 |
| PRELID2 | PRELI domain containing 2 | -0.0395976 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0395877 |
| OSMR | oncostatin M receptor | -0.0385043 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0382646 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0369808 |
| ACTG1 | actin gamma 1 | -0.0365006 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.036476 |
| FTL | ferritin, light polypeptide | -0.0357821 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0346981 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0346115 |
| HLA-B | major histocompatibility complex, class I, B | -0.0345249 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0341089 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0340856 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0339661 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0328 |
| FBN1 | fibrillin 1 | -0.0326142 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.032366 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0321486 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0316126 |
| RPL19 | ribosomal protein L19 | -0.0312641 |
| SMYD3 | SET and MYND domain containing 3 | -0.0307312 |
| DST | dystonin | -0.0300841 |
| RPL8 | ribosomal protein L8 | -0.0299225 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0297634 |
| S100A9 | S100 calcium binding protein A9 | -0.0296588 |
| EXOC4 | exocyst complex component 4 | -0.0292273 |
| RPL34 | ribosomal protein L34 | -0.0291052 |
| GOLGB1 | golgin B1 | -0.0288166 |
| RPL12 | ribosomal protein L12 | -0.0282253 |
| CALD1 | caldesmon 1 | -0.0279309 |
| RPLP1 | ribosomal protein, large, P1 | -0.0278921 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0277697 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0275544 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0268799 |
| RPS19 | ribosomal protein S19 | -0.0260828 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0257095 |
| EGR1 | early growth response 1 | -0.0244945 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0244427 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0241914 |
| H1-0 | H1.0 linker histone | -0.0238359 |
| NRP1 | neuropilin 1 | -0.0237161 |
| S100A10 | S100 calcium binding protein A10 | -0.0233958 |
| ENO1 | enolase 1, (alpha) | -0.0232694 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0231344 |
| PALLD | palladin, cytoskeletal associated protein | -0.0230118 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0227908 |
| RRBP1 | ribosome binding protein 1 | -0.0227153 |
| RPL28 | ribosomal protein L28 | -0.0225248 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0224919 |
| NAV1 | neuron navigator 1 | -0.0224842 |
| CUX1 | cut-like homeobox 1 | -0.0222141 |
| EHBP1 | EH domain binding protein 1 | -0.0221349 |
| EBF1 | early B-cell factor 1 | -0.0219359 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.021922 |
| RPS24 | ribosomal protein S24 | -0.0218744 |
| RPL37A | ribosomal protein L37a | -0.0216505 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0216329 |
| RPS20 | ribosomal protein S20 | -0.0214926 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0212726 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0212594 |
| IL6ST | interleukin 6 signal transducer | -0.0209708 |
| TENM3 | teneurin transmembrane protein 3 | -0.0208386 |
| RPL30 | ribosomal protein L30 | -0.0207205 |
| FOXP1 | forkhead box P1 | -0.0205454 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0204583 |
| RPL23 | ribosomal protein L23 | -0.0201911 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0201123 |
| RPLP0 | ribosomal protein, large, P0 | -0.0199328 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0197125 |
| HDAC9 | histone deacetylase 9 | -0.019438 |
