| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetazolamide perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Acetazolamide_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.0804811 |
| EREG | epiregulin | 0.069683 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0668645 |
| TXNIP | thioredoxin interacting protein | 0.0644324 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0483732 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0467393 |
| LMO7 | LIM domain 7 | 0.0443087 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0431365 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0411049 |
| VEGFA | vascular endothelial growth factor A | 0.0397757 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0387015 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.036884 |
| RNF145 | ring finger protein 145 | 0.0362616 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0355538 |
| DSPP | dentin sialophosphoprotein | 0.034599 |
| PTMA | prothymosin, alpha | 0.0342195 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0338554 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.033361 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0314121 |
| EZR | ezrin | 0.0312157 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0303384 |
| BRD2 | bromodomain containing 2 | 0.0303337 |
| SLK | STE20-like kinase | 0.0296001 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0292074 |
| SNX9 | sorting nexin 9 | 0.0289496 |
| CCNL1 | cyclin L1 | 0.0280315 |
| OGA | O-GlcNAcase | 0.0276916 |
| SPAG9 | sperm associated antigen 9 | 0.0276235 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0270937 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0270695 |
| FNBP1L | formin binding protein 1-like | 0.0269949 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0268476 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0262515 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0259748 |
| NUP58 | nucleoporin 58 | 0.025702 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0256431 |
| RCOR1 | REST corepressor 1 | 0.0252436 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0249158 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0246869 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0246262 |
| DIAPH1 | diaphanous-related formin 1 | 0.0244376 |
| RPL3 | ribosomal protein L3 | 0.0243676 |
| LIPH | lipase, member H | 0.0243666 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0242464 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0236808 |
| COPA | coatomer protein complex, subunit alpha | 0.0234424 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0229698 |
| RPL7A | ribosomal protein L7a | 0.0228397 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0227845 |
| TMF1 | TATA element modulatory factor 1 | 0.022747 |
| YTHDC1 | YTH domain containing 1 | 0.0220614 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0219736 |
| FBXO11 | F-box protein 11 | 0.02168 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0215668 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.021054 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0209885 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0209532 |
| PCBP2 | poly(rC) binding protein 2 | 0.020626 |
| TFG | TRK-fused gene | 0.020583 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0203629 |
| WDR45B | WD repeat domain 45B | 0.0202782 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0202433 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0201781 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0201452 |
| SETD5 | SET domain containing 5 | 0.0200078 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0199925 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0196889 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0191651 |
| TPM4 | tropomyosin 4 | 0.0187647 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0187054 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0186582 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0186557 |
| LAMC2 | laminin, gamma 2 | 0.0186142 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0185503 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0184891 |
| CLIC4 | chloride intracellular channel 4 | 0.0182453 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0181635 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0180805 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0179269 |
| FAM13A | family with sequence similarity 13, member A | 0.0178806 |
| MATR3 | matrin 3 | 0.0178566 |
| SET | SET nuclear proto-oncogene | 0.0178487 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0178404 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0177868 |
| USP53 | ubiquitin specific peptidase 53 | 0.0176669 |
| RAB18 | RAB18, member RAS oncogene family | 0.0174858 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.017446 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0173395 |
| NCOR2 | nuclear receptor corepressor 2 | 0.017298 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0171003 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0169513 |
| VMP1 | vacuole membrane protein 1 | 0.0168097 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0166976 |
| SARNP | SAP domain containing ribonucleoprotein | 0.0166706 |
| KLF6 | Kruppel-like factor 6 | 0.0166 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0164731 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.0164458 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0163553 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0163317 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0162373 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.187873 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.177568 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.134378 |
| NPSR1 | neuropeptide S receptor 1 | -0.125914 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.120808 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.111211 |
| GPHN | gephyrin | -0.110681 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.109041 |
| RNF43 | ring finger protein 43 | -0.0995721 |
| TNS4 | tensin 4 | -0.0944728 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0873505 |
| CADPS | Ca++-dependent secretion activator | -0.0857269 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0803322 |
| NDRG1 | N-myc downstream regulated 1 | -0.0768839 |
| FHIT | fragile histidine triad | -0.0757855 |
| SMYD3 | SET and MYND domain containing 3 | -0.0757655 |
| TMSB10 | thymosin beta 10 | -0.0724678 |
| LOC112694756 | uncharaterized LOC112694756 | -0.071275 |
| ACTN4 | actinin, alpha 4 | -0.0649517 |
| H1-0 | H1.0 linker histone | -0.0644593 |
| NFIA | nuclear factor I/A | -0.0628899 |
| AHNAK | AHNAK nucleoprotein | -0.0607531 |
| NEBL | nebulette | -0.0593644 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0588783 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0587911 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0586985 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0582098 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0581429 |
| RPS24 | ribosomal protein S24 | -0.0575587 |
| KRT8 | keratin 8, type II | -0.0564977 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0560977 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.055705 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0548234 |
| FOXP1 | forkhead box P1 | -0.0546851 |
| RPLP1 | ribosomal protein, large, P1 | -0.0543864 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0538981 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0536945 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0531623 |
| ATXN1 | ataxin 1 | -0.0530741 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0523391 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0506727 |
| CD44 | CD44 molecule (Indian blood group) | -0.0493254 |
| TRIM2 | tripartite motif containing 2 | -0.048627 |
| RPL35A | ribosomal protein L35a | -0.0480776 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0474003 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0461914 |
| PIGR | polymeric immunoglobulin receptor | -0.0452208 |
| TBC1D5 | TBC1 domain family, member 5 | -0.044636 |
| ONECUT3 | one cut homeobox 3 | -0.0444993 |
| RAD51B | RAD51 paralog B | -0.0444828 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.044281 |
| PCDHB16 | protocadherin beta 16 | -0.0436447 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0436088 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0428698 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0421043 |
| NRXN3 | neurexin 3 | -0.0410701 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0406351 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0398707 |
| CANX | calnexin | -0.0394756 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0394407 |
| TFRC | transferrin receptor | -0.0387486 |
| HMGA1 | high mobility group AT-hook 1 | -0.0386767 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0386201 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0380312 |
| PRELID2 | PRELI domain containing 2 | -0.0377204 |
| ABLIM1 | actin binding LIM protein 1 | -0.0377 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.037203 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.03692 |
| MECOM | MDS1 and EVI1 complex locus | -0.0364382 |
| AGR2 | anterior gradient 2 | -0.0363825 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0356085 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0352879 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0351083 |
| PARD3B | par-3 family cell polarity regulator beta | -0.034984 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0349704 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0344026 |
| DIAPH2 | diaphanous-related formin 2 | -0.0343894 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0341073 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0340525 |
| HMGB1 | high mobility group box 1 | -0.0333757 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0332678 |
| EXOC4 | exocyst complex component 4 | -0.033173 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.033168 |
| CCND1 | cyclin D1 | -0.0331438 |
| MSI2 | musashi RNA-binding protein 2 | -0.0327028 |
| MYO1D | myosin ID | -0.0324611 |
| FOXP2 | forkhead box P2 | -0.0322837 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0321973 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0321641 |
| RPL34 | ribosomal protein L34 | -0.0319376 |
| KRT18 | keratin 18, type I | -0.0318622 |
| SBF2 | SET binding factor 2 | -0.0317871 |
| POF1B | premature ovarian failure, 1B | -0.0317704 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0316325 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0312648 |
| TCF12 | transcription factor 12 | -0.0311149 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0310251 |
| SERINC5 | serine incorporator 5 | -0.0309702 |
| TXNRD1 | thioredoxin reductase 1 | -0.0309414 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0309253 |
