| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetazolamide perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Acetazolamide_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.120809 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0942781 |
| SPAG9 | sperm associated antigen 9 | 0.0685809 |
| PTMA | prothymosin, alpha | 0.0685639 |
| CAPRIN2 | caprin family member 2 | 0.0678554 |
| OGA | O-GlcNAcase | 0.0677602 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0655475 |
| TMSB4X | thymosin beta 4, X-linked | 0.0637913 |
| VCL | vinculin | 0.0602286 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0524778 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0483762 |
| TMEM41B | transmembrane protein 41B | 0.0468806 |
| EREG | epiregulin | 0.0447346 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0434642 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0420527 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0409355 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0404863 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0397834 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0389218 |
| KLF6 | Kruppel-like factor 6 | 0.0380385 |
| MKI67 | marker of proliferation Ki-67 | 0.0373869 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0372157 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0368201 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0359815 |
| EZR | ezrin | 0.0353782 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0351286 |
| RTN4 | reticulon 4 | 0.0341771 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0334488 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0327206 |
| ANLN | anillin, actin binding protein | 0.0323743 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0318361 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0316391 |
| MATR3 | matrin 3 | 0.0299286 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0295819 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0294337 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0288988 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.027371 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.027284 |
| TXNIP | thioredoxin interacting protein | 0.0271279 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0270078 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0268289 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0263843 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0261221 |
| RRM2 | ribonucleotide reductase M2 | 0.0255766 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0252792 |
| XPO1 | exportin 1 | 0.0251834 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0251355 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0248087 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0240333 |
| WDR45B | WD repeat domain 45B | 0.0239624 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0237944 |
| MT1X | metallothionein 1X | 0.0235258 |
| NUP58 | nucleoporin 58 | 0.0233564 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0231431 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0231175 |
| USP12 | ubiquitin specific peptidase 12 | 0.0231033 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0229199 |
| SNX14 | sorting nexin 14 | 0.0228491 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0228241 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0228214 |
| ECT2 | epithelial cell transforming 2 | 0.0225162 |
| SDC4 | syndecan 4 | 0.0222959 |
| TPM3 | tropomyosin 3 | 0.0222726 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0219289 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0217338 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0217269 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.021544 |
| IPO7 | importin 7 | 0.0214856 |
| CD44 | CD44 molecule (Indian blood group) | 0.0210482 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0207207 |
| MT2A | metallothionein 2A | 0.0205969 |
| HMGB2 | high mobility group box 2 | 0.0205697 |
| PGK1 | phosphoglycerate kinase 1 | 0.0205687 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0205064 |
| AHNAK | AHNAK nucleoprotein | 0.0204345 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0203867 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0202459 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0201128 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0201105 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0197969 |
| KIF1B | kinesin family member 1B | 0.0196371 |
| ETNK1 | ethanolamine kinase 1 | 0.0195177 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0195177 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0194816 |
| UBC | ubiquitin C | 0.0194731 |
| RBM39 | RNA binding motif protein 39 | 0.0194363 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0192006 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0190822 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0190146 |
| UPP1 | uridine phosphorylase 1 | 0.0189065 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0188638 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0188066 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0187587 |
| RTTN | rotatin | 0.018624 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0186184 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0185815 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0184933 |
| CDC73 | cell division cycle 73 | 0.0182851 |
| MEMO1 | mediator of cell motility 1 | 0.0182274 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0181306 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0915758 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0735031 |
| TMSB10 | thymosin beta 10 | -0.0719867 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0715868 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0663607 |
| HMGA1 | high mobility group AT-hook 1 | -0.0660708 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0656327 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0649211 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0612861 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0585218 |
| CFAP299 | cilia and flagella associated protein 299 | -0.053633 |
| VIM | vimentin | -0.0530783 |
| EHBP1 | EH domain binding protein 1 | -0.0502623 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.049558 |
| TXNRD1 | thioredoxin reductase 1 | -0.0468852 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0422502 |
| EXOC4 | exocyst complex component 4 | -0.0420426 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0411297 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0394163 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0391704 |
| POTEF | POTE ankyrin domain family, member F | -0.0372956 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0368239 |
| EGR1 | early growth response 1 | -0.0344969 |
| CADM2 | cell adhesion molecule 2 | -0.0341862 |
| RPL35A | ribosomal protein L35a | -0.0339426 |
| FTL | ferritin, light polypeptide | -0.0332774 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0325672 |
| TP63 | tumor protein p63 | -0.0321085 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0314465 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0307247 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0287585 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0278725 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0274564 |
| EPHA4 | EPH receptor A4 | -0.0270175 |
| MYADM | myeloid-associated differentiation marker | -0.0255373 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0252902 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0246188 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0244137 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0240471 |
| RPL23 | ribosomal protein L23 | -0.0230829 |
| MYOF | myoferlin | -0.0227795 |
| ACTG1 | actin gamma 1 | -0.022753 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0225339 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0223679 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0219567 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0215883 |
| TMEM123 | transmembrane protein 123 | -0.0209454 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0202822 |
| TSC22D1 | TSC22 domain family, member 1 | -0.020272 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0201517 |
| YBX1 | Y box binding protein 1 | -0.0198516 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0196874 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0192534 |
| EFNA5 | ephrin-A5 | -0.0190208 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0190149 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0189797 |
| RAD51B | RAD51 paralog B | -0.0188764 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0188587 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.01872 |
| TNS3 | tensin 3 | -0.0187099 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0186815 |
| RPS8 | ribosomal protein S8 | -0.0186735 |
| WDR27 | WD repeat domain 27 | -0.0186477 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0183856 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0183453 |
| ATN1 | atrophin 1 | -0.0182112 |
| PFN1 | profilin 1 | -0.0181933 |
| PCBP2 | poly(rC) binding protein 2 | -0.0179812 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0178537 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0174851 |
| NDRG1 | N-myc downstream regulated 1 | -0.0174498 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0173162 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.01731 |
| HDAC9 | histone deacetylase 9 | -0.0172463 |
| DNER | delta/notch-like EGF repeat containing | -0.0169576 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0168768 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0167669 |
| PDE10A | phosphodiesterase 10A | -0.0166689 |
| COL5A2 | collagen, type V, alpha 2 | -0.0165553 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0164915 |
| HM13 | histocompatibility (minor) 13 | -0.0164659 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0164348 |
| RGS5 | regulator of G-protein signaling 5 | -0.016427 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.016348 |
| TAPBP | TAP binding protein (tapasin) | -0.0163066 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.016056 |
| TPI1 | triosephosphate isomerase 1 | -0.0157606 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.015707 |
| RPL28 | ribosomal protein L28 | -0.0155464 |
| SMIM44 | small integral membrane protein 44 | -0.0155264 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0155179 |
| SETX | senataxin | -0.0154948 |
| NUCB2 | nucleobindin 2 | -0.0154513 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0154276 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0153804 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0151788 |
| CALR | calreticulin | -0.0150981 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0150746 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0148995 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0148814 |
