| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetazolamide perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Acetazolamide_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.0692728 |
| LAMC2 | laminin, gamma 2 | 0.0569125 |
| LAMA4 | laminin, alpha 4 | 0.0496088 |
| NGLY1 | N-glycanase 1 | 0.0453418 |
| LAMB3 | laminin, beta 3 | 0.0451289 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0430141 |
| SPAG9 | sperm associated antigen 9 | 0.0388424 |
| LMO7 | LIM domain 7 | 0.0383077 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0372524 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0363511 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0346768 |
| OGA | O-GlcNAcase | 0.0346304 |
| TOP1 | topoisomerase (DNA) I | 0.0338598 |
| TMEM165 | transmembrane protein 165 | 0.0314747 |
| MKI67 | marker of proliferation Ki-67 | 0.0306078 |
| H1-0 | H1.0 linker histone | 0.0298199 |
| TES | testin LIM domain protein | 0.02971 |
| GOLGA4 | golgin A4 | 0.0269541 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0262314 |
| OSMR | oncostatin M receptor | 0.0262308 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0261776 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0260799 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0256193 |
| SUCO | SUN domain containing ossification factor | 0.0251526 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0250476 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0243251 |
| TMF1 | TATA element modulatory factor 1 | 0.0242305 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0240673 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0233012 |
| ATP13A3 | ATPase type 13A3 | 0.0232482 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0225767 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0224363 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0217526 |
| TMEM87A | transmembrane protein 87A | 0.0216827 |
| SON | SON DNA binding protein | 0.0212409 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0207688 |
| ZNF292 | zinc finger protein 292 | 0.0205506 |
| MATR3 | matrin 3 | 0.0203547 |
| HELZ | helicase with zinc finger | 0.020235 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0202091 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0201828 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0197761 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0195589 |
| UBE4A | ubiquitination factor E4A | 0.0195425 |
| CUL3 | cullin 3 | 0.0194979 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0193278 |
| FNBP1L | formin binding protein 1-like | 0.0191539 |
| ANO6 | anoctamin 6 | 0.0187971 |
| NCKAP1 | NCK-associated protein 1 | 0.0186809 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0186357 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0186263 |
| YTHDC1 | YTH domain containing 1 | 0.0183891 |
| RBM25 | RNA binding motif protein 25 | 0.0182951 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0181874 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0180702 |
| ZFR | zinc finger RNA binding protein | 0.0174717 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0174582 |
| ARRDC3 | arrestin domain containing 3 | 0.0172786 |
| RUNX1 | runt-related transcription factor 1 | 0.0171878 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0169726 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0166376 |
| EP300 | E1A binding protein p300 | 0.016394 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.0163343 |
| MORF4L2 | mortality factor 4 like 2 | 0.0162585 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0162056 |
| UBE3A | ubiquitin protein ligase E3A | 0.0161883 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0161006 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0160504 |
| SEPTIN2 | septin 2 | 0.0160215 |
| RBM26 | RNA binding motif protein 26 | 0.0159661 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0158567 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0158214 |
| RASA2 | RAS p21 protein activator 2 | 0.0157932 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0156578 |
| SYAP1 | synapse associated protein 1 | 0.0155392 |
| SEPTIN10 | septin 10 | 0.0155005 |
| CDC73 | cell division cycle 73 | 0.0154986 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0154272 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0153738 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.015331 |
| SRP54 | signal recognition particle 54kDa | 0.0152898 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.015285 |
| METTL9 | methyltransferase like 9 | 0.0150592 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0150033 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) | 0.0150013 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.014962 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0149454 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0149171 |
| KMT5B | lysine methyltransferase 5B | 0.0146754 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0144813 |
| MT1X | metallothionein 1X | 0.0144753 |
| SLTM | SAFB-like, transcription modulator | 0.0144393 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0141904 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0140999 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0140204 |
| ATP11B | ATPase, class VI, type 11B | 0.0140061 |
| ANXA5 | annexin A5 | 0.0139146 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0138672 |
| RNF145 | ring finger protein 145 | 0.0138587 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0137353 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.266954 |
| EGFR | epidermal growth factor receptor | -0.259044 |
| TMSB10 | thymosin beta 10 | -0.162059 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.11454 |
| EFNA5 | ephrin-A5 | -0.105999 |
| PTMA | prothymosin, alpha | -0.102882 |
| PKM | pyruvate kinase, muscle | -0.0942827 |
| NDRG1 | N-myc downstream regulated 1 | -0.0920966 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0891993 |
| CST3 | cystatin C | -0.0832729 |
| ASPH | aspartate beta-hydroxylase | -0.0824962 |
| ACTG1 | actin gamma 1 | -0.0816659 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0800864 |
| INTS6 | integrator complex subunit 6 | -0.0780896 |
| MCL1 | myeloid cell leukemia 1 | -0.069028 |
| RPL35A | ribosomal protein L35a | -0.0689686 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0685011 |
| RNF213 | ring finger protein 213 | -0.0682587 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0657585 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0655204 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0642743 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0630847 |
| EGR1 | early growth response 1 | -0.0608601 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0599226 |
| S100A10 | S100 calcium binding protein A10 | -0.0565737 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0562223 |
| HLA-B | major histocompatibility complex, class I, B | -0.0559004 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0542297 |
| TXNRD1 | thioredoxin reductase 1 | -0.0517325 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0512247 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0511815 |
| RPS25 | ribosomal protein S25 | -0.0504326 |
| B2M | beta-2-microglobulin | -0.0503094 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0497556 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0490352 |
| CUX1 | cut-like homeobox 1 | -0.0489609 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0480391 |
| RPL31 | ribosomal protein L31 | -0.0464272 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0443932 |
| RPLP1 | ribosomal protein, large, P1 | -0.0443911 |
| TNS3 | tensin 3 | -0.0439116 |
| KRT7 | keratin 7, type II | -0.0438144 |
| RPS29 | ribosomal protein S29 | -0.0434192 |
| RPS24 | ribosomal protein S24 | -0.0425867 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0425733 |
| FUS | FUS RNA binding protein | -0.0419231 |
| SP100 | SP100 nuclear antigen | -0.0412212 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0411198 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0410105 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0407408 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0401539 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0400086 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0398011 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0389166 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0388185 |
| RPL37A | ribosomal protein L37a | -0.0381141 |
| FBXO11 | F-box protein 11 | -0.0380108 |
| PRKCA | protein kinase C, alpha | -0.0374234 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0373824 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0369498 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0366162 |
| FTL | ferritin, light polypeptide | -0.0365855 |
| AHNAK | AHNAK nucleoprotein | -0.0364226 |
| CCND1 | cyclin D1 | -0.0362689 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0357152 |
| FOXP1 | forkhead box P1 | -0.0357143 |
| MYO1E | myosin IE | -0.0353725 |
| RPS23 | ribosomal protein S23 | -0.0353592 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0344384 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0339299 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0338589 |
| PARD3 | par-3 family cell polarity regulator | -0.033853 |
| TRIM56 | tripartite motif containing 56 | -0.0337152 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0333601 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0332979 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0329437 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0329357 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0329191 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0325072 |
| RPS27A | ribosomal protein S27a | -0.0322836 |
| MX1 | MX dynamin-like GTPase 1 | -0.0317352 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0314967 |
| RPL34 | ribosomal protein L34 | -0.0314501 |
| S100A9 | S100 calcium binding protein A9 | -0.03083 |
| CTBP2 | C-terminal binding protein 2 | -0.0306524 |
| RAB10 | RAB10, member RAS oncogene family | -0.030582 |
| S100P | S100 calcium binding protein P | -0.0305698 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0303231 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0302435 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0302233 |
| SVIL | supervillin | -0.0300938 |
| RPL37 | ribosomal protein L37 | -0.0299122 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0296682 |
| IER3 | immediate early response 3 | -0.0296183 |
| AGR2 | anterior gradient 2 | -0.0295399 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.029311 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0292154 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0291511 |
| CMIP | c-Maf inducing protein | -0.0287376 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0283533 |
