| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetazolamide perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Acetazolamide_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.149747 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.129625 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.122776 |
| FAM13A | family with sequence similarity 13, member A | 0.111811 |
| GOLGA4 | golgin A4 | 0.101866 |
| OGA | O-GlcNAcase | 0.0994119 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0907308 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0850377 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0819556 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0754287 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0720381 |
| RBM39 | RNA binding motif protein 39 | 0.067325 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0653258 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0622496 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0616837 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0609657 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0607197 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0570489 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0569552 |
| ATP13A3 | ATPase type 13A3 | 0.0556656 |
| JMJD1C | jumonji domain containing 1C | 0.0544833 |
| PRELID2 | PRELI domain containing 2 | 0.0542469 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0530241 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0520791 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0512729 |
| SMAD3 | SMAD family member 3 | 0.0506548 |
| USP3 | ubiquitin specific peptidase 3 | 0.0503751 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0502998 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0492451 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0489331 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0488231 |
| SIK3 | SIK family kinase 3 | 0.0484433 |
| RIOK3 | RIO kinase 3 | 0.0471035 |
| ZNF292 | zinc finger protein 292 | 0.045306 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0450897 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0448652 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0446524 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0440677 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0439239 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0434491 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0423847 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0422083 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0408579 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0407931 |
| HELZ | helicase with zinc finger | 0.0407143 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0406943 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0406889 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0402734 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.040072 |
| NGLY1 | N-glycanase 1 | 0.039546 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0394525 |
| COPA | coatomer protein complex, subunit alpha | 0.039267 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0389394 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0379584 |
| CD109 | CD109 molecule | 0.0378161 |
| SPAG9 | sperm associated antigen 9 | 0.037029 |
| COG5 | component of oligomeric golgi complex 5 | 0.0362757 |
| SETD5 | SET domain containing 5 | 0.0361651 |
| PARD3 | par-3 family cell polarity regulator | 0.0361237 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0353941 |
| APP | amyloid beta (A4) precursor protein | 0.0346928 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0345527 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0343322 |
| WDR45B | WD repeat domain 45B | 0.0339257 |
| ADD3 | adducin 3 (gamma) | 0.0338262 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0336755 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0335621 |
| RNF145 | ring finger protein 145 | 0.0331513 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0323691 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0322664 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0321726 |
| RUNX1 | runt-related transcription factor 1 | 0.0320338 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0319128 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0315299 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0313763 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0313314 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0312867 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0311792 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0311718 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0309859 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0307907 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0307565 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0307378 |
| CDC73 | cell division cycle 73 | 0.0307253 |
| PCBP2 | poly(rC) binding protein 2 | 0.0306059 |
| YEATS2 | YEATS domain containing 2 | 0.0305548 |
| FLNB | filamin B, beta | 0.0304681 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.03028 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0301411 |
| MYOF | myoferlin | 0.0299938 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0299069 |
| SBF2 | SET binding factor 2 | 0.029682 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0296557 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0295855 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0294901 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.029301 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0290307 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0289897 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0289232 |
| ARRDC3 | arrestin domain containing 3 | 0.028804 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0792463 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0792416 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0739169 |
| VIM | vimentin | -0.066406 |
| NRG1 | neuregulin 1 | -0.0602705 |
| EGR1 | early growth response 1 | -0.0577184 |
| HMGA2 | high mobility group AT-hook 2 | -0.0558796 |
| CDH13 | cadherin 13 | -0.0550436 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0527894 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0518429 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0504831 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0468082 |
| FTL | ferritin, light polypeptide | -0.0461177 |
| GLCCI1 | glucocorticoid induced 1 | -0.0459147 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0459008 |
| CD44 | CD44 molecule (Indian blood group) | -0.0434474 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0428593 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0427669 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.042736 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0419466 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0402854 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0376889 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.037645 |
| RAD51B | RAD51 paralog B | -0.0348227 |
| RPLP1 | ribosomal protein, large, P1 | -0.0348042 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0342359 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0336992 |
| GLIS3 | GLIS family zinc finger 3 | -0.0317026 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.03124 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0308825 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0305133 |
| TGFB1 | transforming growth factor, beta 1 | -0.0304536 |
| HMGA1 | high mobility group AT-hook 1 | -0.0302886 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0299619 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0290648 |
| RPL35A | ribosomal protein L35a | -0.0287948 |
| NTN4 | netrin 4 | -0.0286673 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0286133 |
| RPL36 | ribosomal protein L36 | -0.0283644 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0272786 |
| LOX | lysyl oxidase | -0.0270331 |
| EFNA5 | ephrin-A5 | -0.0265877 |
| EGFR | epidermal growth factor receptor | -0.0265565 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0264653 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0262977 |
| AADAC | arylacetamide deacetylase | -0.0258657 |
| EXOC4 | exocyst complex component 4 | -0.0258209 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0257026 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.025676 |
| CLMP | CXADR-like membrane protein | -0.0254103 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0253149 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0248285 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0243493 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0242906 |
| MYADM | myeloid-associated differentiation marker | -0.0238926 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0238311 |
| NDRG1 | N-myc downstream regulated 1 | -0.0234878 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0234332 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.023345 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0232359 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0231489 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0229918 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0229327 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0227422 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0223776 |
| RPS19 | ribosomal protein S19 | -0.0223759 |
| EHBP1 | EH domain binding protein 1 | -0.0221067 |
| FRMD4A | FERM domain containing 4A | -0.0215984 |
| IL1B | interleukin 1, beta | -0.0215034 |
| TNNC1 | troponin C type 1 (slow) | -0.021368 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.021087 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0210529 |
| RPL37A | ribosomal protein L37a | -0.0207235 |
| S100A10 | S100 calcium binding protein A10 | -0.0205392 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0204513 |
| MCL1 | myeloid cell leukemia 1 | -0.0204481 |
| ETV6 | ets variant 6 | -0.0204343 |
| S100A6 | S100 calcium binding protein A6 | -0.020353 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0202121 |
| WLS | wntless Wnt ligand secretion mediator | -0.0200447 |
| RPL34 | ribosomal protein L34 | -0.0199375 |
| B2M | beta-2-microglobulin | -0.0192316 |
| HLA-B | major histocompatibility complex, class I, B | -0.0187471 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0186794 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0186112 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0186073 |
| RNF213 | ring finger protein 213 | -0.0185959 |
| ATG7 | autophagy related 7 | -0.0185141 |
| MTSS1 | metastasis suppressor 1 | -0.0183844 |
| RPL31 | ribosomal protein L31 | -0.0181559 |
| RPS6 | ribosomal protein S6 | -0.0180689 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0179728 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0178208 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0177125 |
| MX2 | MX dynamin-like GTPase 2 | -0.0177031 |
| IER3 | immediate early response 3 | -0.017693 |
| ECE1 | endothelin converting enzyme 1 | -0.0175533 |
| RPS29 | ribosomal protein S29 | -0.0174062 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0173838 |
| FBN1 | fibrillin 1 | -0.0173482 |
