| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetazolamide perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Acetazolamide_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.155696 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.144482 |
| CCNL1 | cyclin L1 | 0.125394 |
| USP34 | ubiquitin specific peptidase 34 | 0.117046 |
| FNDC3B | fibronectin type III domain containing 3B | 0.11386 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.109623 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.106457 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.106234 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.104774 |
| SPAG9 | sperm associated antigen 9 | 0.100054 |
| SBF2 | SET binding factor 2 | 0.0992607 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0946978 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0923551 |
| SQSTM1 | sequestosome 1 | 0.0877727 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0862138 |
| MEF2A | myocyte enhancer factor 2A | 0.0858999 |
| EGR1 | early growth response 1 | 0.0848836 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.083561 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0802807 |
| PCBP2 | poly(rC) binding protein 2 | 0.076512 |
| FAM13A | family with sequence similarity 13, member A | 0.068871 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0685489 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0670397 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.06455 |
| COG5 | component of oligomeric golgi complex 5 | 0.0627194 |
| MT2A | metallothionein 2A | 0.0621842 |
| ZNF638 | zinc finger protein 638 | 0.0610525 |
| GLG1 | golgi glycoprotein 1 | 0.0592494 |
| RBM39 | RNA binding motif protein 39 | 0.0574243 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.055881 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0542723 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0528549 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0526455 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0517118 |
| FNIP1 | folliculin interacting protein 1 | 0.0510638 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0504486 |
| CARD16 | caspase recruitment domain family, member 16 | 0.04947 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0494215 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0481576 |
| ACTN4 | actinin, alpha 4 | 0.0473714 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0472469 |
| PDE8A | phosphodiesterase 8A | 0.0465113 |
| RPL37A | ribosomal protein L37a | 0.0440866 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0429255 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.042688 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0423145 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0416162 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.039839 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0393508 |
| PTK2 | protein tyrosine kinase 2 | 0.0379783 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0375019 |
| JMJD1C | jumonji domain containing 1C | 0.036946 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0365084 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0361572 |
| RPS12 | ribosomal protein S12 | 0.0354783 |
| GPC6 | glypican 6 | 0.0343919 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.033734 |
| RPS3 | ribosomal protein S3 | 0.0334867 |
| TPR | translocated promoter region, nuclear basket protein | 0.0331834 |
| EGFR | epidermal growth factor receptor | 0.0322155 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0319858 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0316847 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0307289 |
| DENND1A | DENN/MADD domain containing 1A | 0.0295173 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0294068 |
| AK1 | adenylate kinase 1 | 0.0266551 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.025484 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0247425 |
| HMGA1 | high mobility group AT-hook 1 | 0.0239839 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0228574 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0219829 |
| DSCAM | Down syndrome cell adhesion molecule | 0.021657 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0212104 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0205615 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0189169 |
| ASPH | aspartate beta-hydroxylase | 0.018864 |
| ATP13A3 | ATPase type 13A3 | 0.0177257 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.017578 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0156808 |
| CNKSR3 | CNKSR family member 3 | 0.0154757 |
| B2M | beta-2-microglobulin | 0.0152814 |
| NBAS | neuroblastoma amplified sequence | 0.0139399 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.01371 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0133981 |
| RPLP1 | ribosomal protein, large, P1 | 0.0131432 |
| NF1 | neurofibromin 1 | 0.0129261 |
| LMO7 | LIM domain 7 | 0.0128343 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0128026 |
| FLNB | filamin B, beta | 0.0124499 |
| RPS6 | ribosomal protein S6 | 0.0122483 |
| RPL35A | ribosomal protein L35a | 0.0119994 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0118215 |
| LDHA | lactate dehydrogenase A | 0.011252 |
| DST | dystonin | 0.0105522 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0103294 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.00832571 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.00825185 |
| ACTG1 | actin gamma 1 | 0.0076149 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.00742951 |
| RNF213 | ring finger protein 213 | 0.00725139 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.183889 |
| FN1 | fibronectin 1 | -0.165149 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.148221 |
| PEG10 | paternally expressed 10 | -0.120555 |
| FTL | ferritin, light polypeptide | -0.119503 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.108506 |
| CADM2 | cell adhesion molecule 2 | -0.0998661 |
| GOLGB1 | golgin B1 | -0.099671 |
| ZNF608 | zinc finger protein 608 | -0.0964381 |
| VIM | vimentin | -0.0954383 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0869204 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0860374 |
| TXNRD1 | thioredoxin reductase 1 | -0.0817246 |
| PDE10A | phosphodiesterase 10A | -0.0780542 |
| HMGA2 | high mobility group AT-hook 2 | -0.0726087 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0722682 |
| CCNI | cyclin I | -0.0693539 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.069001 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0688122 |
| ARRDC3 | arrestin domain containing 3 | -0.0684308 |
| CANX | calnexin | -0.0679456 |
| PTMA | prothymosin, alpha | -0.0658599 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.065332 |
| NAV2 | neuron navigator 2 | -0.0638099 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0615521 |
| S100A10 | S100 calcium binding protein A10 | -0.0609745 |
| RORA | RAR-related orphan receptor A | -0.0607531 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0592332 |
| NDRG1 | N-myc downstream regulated 1 | -0.0591511 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0574494 |
| MED13 | mediator complex subunit 13 | -0.0568931 |
| IGF2 | insulin-like growth factor 2 | -0.0563794 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0558555 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0546717 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0544464 |
| TMSB10 | thymosin beta 10 | -0.0537981 |
| ANXA2 | annexin A2 | -0.051676 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.048528 |
| RPL37 | ribosomal protein L37 | -0.0482208 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0459245 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0451874 |
| TPM4 | tropomyosin 4 | -0.0418748 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0414408 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0413785 |
| ATP11A | ATPase, class VI, type 11A | -0.0408757 |
| VCL | vinculin | -0.0404793 |
| GOLGA4 | golgin A4 | -0.0404715 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0402711 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0400057 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.039812 |
| RPL19 | ribosomal protein L19 | -0.0384842 |
| STC1 | stanniocalcin 1 | -0.0381012 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0360812 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0353769 |
| INTS6 | integrator complex subunit 6 | -0.0351267 |
| HDLBP | high density lipoprotein binding protein | -0.0341006 |
| EFNA5 | ephrin-A5 | -0.0340118 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0339464 |
| PRKCA | protein kinase C, alpha | -0.0334552 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0318497 |
| SETD5 | SET domain containing 5 | -0.0309405 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0307808 |
| RAB2A | RAB2A, member RAS oncogene family | -0.029677 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0294917 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0289984 |
| RPL30 | ribosomal protein L30 | -0.027998 |
| MYO1E | myosin IE | -0.0276349 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0266031 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0262248 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0245244 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0236582 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0236138 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0236009 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0234807 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0228667 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0216799 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0213872 |
| ATXN1 | ataxin 1 | -0.0206098 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.020563 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0202558 |
| CD44 | CD44 molecule (Indian blood group) | -0.0199151 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0196191 |
| ENO1 | enolase 1, (alpha) | -0.0193489 |
| RPL11 | ribosomal protein L11 | -0.0187068 |
| ATF6 | activating transcription factor 6 | -0.0180129 |
| RPS8 | ribosomal protein S8 | -0.0177876 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0174523 |
| ANKRD12 | ankyrin repeat domain 12 | -0.017436 |
| RPLP0 | ribosomal protein, large, P0 | -0.0156461 |
| OGA | O-GlcNAcase | -0.0156297 |
| BBX | bobby sox homolog (Drosophila) | -0.0153671 |
| PGK1 | phosphoglycerate kinase 1 | -0.015349 |
| CDCP1 | CUB domain containing protein 1 | -0.0143113 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0126147 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0123719 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0114265 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0111123 |
| RPL23 | ribosomal protein L23 | -0.0110128 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0108802 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0107145 |
