| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetazolamide perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Acetazolamide_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.180829 |
| PTMA | prothymosin, alpha | 0.143202 |
| SPAG9 | sperm associated antigen 9 | 0.0926674 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0842288 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0829393 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0775593 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0772004 |
| THBS1 | thrombospondin 1 | 0.0753416 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0746511 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0722695 |
| ZNF292 | zinc finger protein 292 | 0.069262 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0683133 |
| MATR3 | matrin 3 | 0.066628 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0661524 |
| ANXA5 | annexin A5 | 0.064636 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.063415 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0627623 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0621089 |
| HDAC9 | histone deacetylase 9 | 0.0609107 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.059657 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0561768 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0558261 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0547832 |
| CDC73 | cell division cycle 73 | 0.0539268 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0524971 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0515841 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0513749 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0504129 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0490799 |
| STAG2 | stromal antigen 2 | 0.0490735 |
| PLPP1 | phospholipid phosphatase 1 | 0.0476748 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0473771 |
| MYO10 | myosin X | 0.0467728 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0460737 |
| SET | SET nuclear proto-oncogene | 0.0448908 |
| FAM168A | family with sequence similarity 168, member A | 0.0443226 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.043792 |
| ENAH | enabled homolog (Drosophila) | 0.0436383 |
| TMSB4X | thymosin beta 4, X-linked | 0.0434936 |
| OGA | O-GlcNAcase | 0.0430964 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0421621 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0416175 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0408527 |
| CANX | calnexin | 0.0407408 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.039604 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0394198 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0393091 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0391915 |
| USP53 | ubiquitin specific peptidase 53 | 0.0388305 |
| WDR43 | WD repeat domain 43 | 0.0385001 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0382401 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0377964 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0377487 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0371744 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0370523 |
| QKI | QKI, KH domain containing, RNA binding | 0.0370127 |
| TLK1 | tousled-like kinase 1 | 0.0365035 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0364764 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0362911 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0361416 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0359086 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0358551 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0358015 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0357797 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0356314 |
| APP | amyloid beta (A4) precursor protein | 0.0352527 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0350349 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0348899 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0345118 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0341622 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.03377 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0337307 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0337307 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0333845 |
| MB21D2 | Mab-21 domain containing 2 | 0.033281 |
| NUP58 | nucleoporin 58 | 0.0329541 |
| PDS5B | PDS5 cohesin associated factor B | 0.0326913 |
| TPR | translocated promoter region, nuclear basket protein | 0.0326334 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0323891 |
| XPO4 | exportin 4 | 0.0320298 |
| KIF5B | kinesin family member 5B | 0.0318659 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0312486 |
| HDAC2 | histone deacetylase 2 | 0.0311322 |
| MEMO1 | mediator of cell motility 1 | 0.0309463 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0308656 |
| CYRIB | CYFIP related Rac1 interactor B | 0.030843 |
| TMEM41B | transmembrane protein 41B | 0.0306964 |
| PCDH18 | protocadherin 18 | 0.0305557 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0305271 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0302125 |
| RBM33 | RNA binding motif protein 33 | 0.0301353 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0300218 |
| NOP58 | NOP58 ribonucleoprotein | 0.0299609 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0297976 |
| SSR1 | signal sequence receptor, alpha | 0.0294473 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0289854 |
| ANXA2 | annexin A2 | 0.0286688 |
| CCN2 | cellular communication network factor 2 | 0.0285678 |
| ANXA1 | annexin A1 | 0.0284335 |
| ZNF451 | zinc finger protein 451 | 0.0283511 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.127225 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.118182 |
| CADM2 | cell adhesion molecule 2 | -0.105277 |
| COL11A1 | collagen, type XI, alpha 1 | -0.086938 |
| VIM | vimentin | -0.0790531 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0771162 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0766784 |
| PEG10 | paternally expressed 10 | -0.0742803 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0705818 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.066158 |
| RPL35A | ribosomal protein L35a | -0.0629961 |
| PCDH9 | protocadherin 9 | -0.0559928 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0526913 |
| TENM3 | teneurin transmembrane protein 3 | -0.048983 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0486952 |
| RAD51B | RAD51 paralog B | -0.0480968 |
| PFN1 | profilin 1 | -0.0478854 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0468106 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0461212 |
| FOXP2 | forkhead box P2 | -0.0458559 |
| COL5A2 | collagen, type V, alpha 2 | -0.0455033 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0430888 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0425342 |
| ACTG1 | actin gamma 1 | -0.041741 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0415346 |
| TUBA1B | tubulin, alpha 1b | -0.0390408 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0382362 |
| RPS19 | ribosomal protein S19 | -0.0381957 |
| GPC3 | glypican 3 | -0.0379826 |
| TMSB10 | thymosin beta 10 | -0.0356023 |
| RPLP0 | ribosomal protein, large, P0 | -0.0352625 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.0349024 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0340957 |
| USP34 | ubiquitin specific peptidase 34 | -0.0337629 |
| SHROOM3 | shroom family member 3 | -0.0331431 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0331 |
| HMGB1 | high mobility group box 1 | -0.0330511 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0329328 |
| PCDH7 | protocadherin 7 | -0.0319808 |
| METAP2 | methionyl aminopeptidase 2 | -0.0314908 |
| MEIS2 | Meis homeobox 2 | -0.0313863 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0313301 |
| RPLP1 | ribosomal protein, large, P1 | -0.0312046 |
| RPS27A | ribosomal protein S27a | -0.0307365 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0299943 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0298939 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0297168 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0293029 |
| SKIL | SKI-like proto-oncogene | -0.0292256 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0291081 |
| POTEF | POTE ankyrin domain family, member F | -0.0283871 |
| ACTN4 | actinin, alpha 4 | -0.0282715 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0277003 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0274321 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0269293 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.026922 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0267877 |
| FBXO17 | F-box protein 17 | -0.0266517 |
| NTM | neurotrimin | -0.0264794 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0262602 |
| RASAL2 | RAS protein activator like 2 | -0.0262499 |
| TOX | thymocyte selection-associated high mobility group box | -0.0260513 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0257328 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0256011 |
| PRORP | protein only RNase P catalytic subunit | -0.0255942 |
| MAGT1 | magnesium transporter 1 | -0.0255814 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0252131 |
| R3HDM1 | R3H domain containing 1 | -0.0250528 |
| RPS24 | ribosomal protein S24 | -0.0247047 |
| RPL35 | ribosomal protein L35 | -0.0246169 |
| RPL32 | ribosomal protein L32 | -0.0245478 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0243365 |
| CENPF | centromere protein F, 350/400kDa | -0.0243043 |
| SGO2 | shugoshin 2 | -0.0242946 |
| JMJD1C | jumonji domain containing 1C | -0.0240771 |
| GOLIM4 | golgi integral membrane protein 4 | -0.0240736 |
| LYST | lysosomal trafficking regulator | -0.0239881 |
| CDH19 | cadherin 19, type 2 | -0.0236801 |
| NDRG1 | N-myc downstream regulated 1 | -0.0236115 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0235719 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0229916 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.022859 |
| HMGA1 | high mobility group AT-hook 1 | -0.0228539 |
| FRMD5 | FERM domain containing 5 | -0.0228002 |
| FTL | ferritin, light polypeptide | -0.0227446 |
| RPS6 | ribosomal protein S6 | -0.0224814 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0224504 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.022438 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.022172 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0221392 |
| ITM2B | integral membrane protein 2B | -0.0217941 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.021708 |
| PROS1 | protein S (alpha) | -0.0216928 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0216509 |
| ZNF385D | zinc finger protein 385D | -0.0213673 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0213505 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.0213422 |
| PGK1 | phosphoglycerate kinase 1 | -0.0208755 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0206609 |
| PRR16 | proline rich 16 | -0.0206096 |
