| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetazolamide perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Acetazolamide_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.108663 |
| GOLGA4 | golgin A4 | 0.0957867 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0874429 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0773691 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0736093 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0673431 |
| TMSB4X | thymosin beta 4, X-linked | 0.0637662 |
| ZNF292 | zinc finger protein 292 | 0.058272 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0566421 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0509706 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0481622 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0476414 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0473738 |
| RTN4 | reticulon 4 | 0.0473682 |
| RNF145 | ring finger protein 145 | 0.0449618 |
| RBM39 | RNA binding motif protein 39 | 0.0449118 |
| QKI | QKI, KH domain containing, RNA binding | 0.0446923 |
| NBAS | neuroblastoma amplified sequence | 0.0436883 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0425054 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.042364 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0423375 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0421648 |
| ANK2 | ankyrin 2, neuronal | 0.0419675 |
| CDC73 | cell division cycle 73 | 0.0415522 |
| FLNB | filamin B, beta | 0.0413903 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0405983 |
| NUP58 | nucleoporin 58 | 0.0401754 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0390953 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.039034 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0382407 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0375832 |
| TXNIP | thioredoxin interacting protein | 0.0375517 |
| CCNL1 | cyclin L1 | 0.0369212 |
| NCKAP1 | NCK-associated protein 1 | 0.0365169 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0363562 |
| TMEM41B | transmembrane protein 41B | 0.0363087 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0361334 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0358089 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0356998 |
| COG5 | component of oligomeric golgi complex 5 | 0.035448 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0350505 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0334751 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0318157 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0316959 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0316667 |
| VMP1 | vacuole membrane protein 1 | 0.0314403 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0311177 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0309644 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0306285 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0305354 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0305112 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0299826 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0295734 |
| ECT2 | epithelial cell transforming 2 | 0.0289213 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0288339 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0286256 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0284947 |
| SQSTM1 | sequestosome 1 | 0.0280327 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0278517 |
| JMJD1C | jumonji domain containing 1C | 0.0276486 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0275266 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0274655 |
| OGA | O-GlcNAcase | 0.027211 |
| EZR | ezrin | 0.0271618 |
| TFG | TRK-fused gene | 0.0271085 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.027038 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0270114 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0269778 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0266486 |
| SUCO | SUN domain containing ossification factor | 0.0262367 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0258963 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0257786 |
| TMF1 | TATA element modulatory factor 1 | 0.0257221 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0257028 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0256973 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.025637 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0254986 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0254713 |
| COG6 | component of oligomeric golgi complex 6 | 0.0254154 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0253804 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0253314 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0250605 |
| COPA | coatomer protein complex, subunit alpha | 0.0250456 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0250059 |
| ZNF608 | zinc finger protein 608 | 0.0249404 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0247744 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0247224 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0246297 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0244926 |
| MATR3 | matrin 3 | 0.0244746 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0240557 |
| S100A6 | S100 calcium binding protein A6 | 0.0239802 |
| DENND4A | DENN/MADD domain containing 4A | 0.0239626 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0237672 |
| SRP54 | signal recognition particle 54kDa | 0.0235881 |
| YAP1 | Yes-associated protein 1 | 0.0235283 |
| RAB6A | RAB6A, member RAS oncogene family | 0.023434 |
| TNPO1 | transportin 1 | 0.023296 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0232925 |
| XPO1 | exportin 1 | 0.0231834 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.130823 |
| BMP10 | bone morphogenetic protein 10 | -0.124542 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.11701 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.112751 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0935012 |
| FOXP1 | forkhead box P1 | -0.089779 |
| VCL | vinculin | -0.0871756 |
| PTMA | prothymosin, alpha | -0.083104 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0728313 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0724173 |
| RPL35A | ribosomal protein L35a | -0.0655771 |
| AHNAK | AHNAK nucleoprotein | -0.0565021 |
| GLI3 | GLI family zinc finger 3 | -0.0502546 |
| MKI67 | marker of proliferation Ki-67 | -0.0501397 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0470449 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0460406 |
| RPS8 | ribosomal protein S8 | -0.0460028 |
| DIAPH3 | diaphanous-related formin 3 | -0.0448872 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0444131 |
| NAV2 | neuron navigator 2 | -0.0435192 |
| CCND1 | cyclin D1 | -0.0430053 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0411492 |
| HSPB1 | heat shock 27kDa protein 1 | -0.040993 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0404278 |
| CENPF | centromere protein F, 350/400kDa | -0.0401173 |
| RPLP1 | ribosomal protein, large, P1 | -0.0394734 |
| NBEA | neurobeachin | -0.0391254 |
| RPL34 | ribosomal protein L34 | -0.0386817 |
| ACTG1 | actin gamma 1 | -0.0379982 |
| PKM | pyruvate kinase, muscle | -0.0369259 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0349083 |
| CUX1 | cut-like homeobox 1 | -0.0346825 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0346184 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0344605 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0333259 |
| GLI2 | GLI family zinc finger 2 | -0.0331193 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0324069 |
| RPS6 | ribosomal protein S6 | -0.0319363 |
| MYO5C | myosin VC | -0.03177 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0316375 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0315693 |
| S100A4 | S100 calcium binding protein A4 | -0.0314545 |
| PDE7B | phosphodiesterase 7B | -0.0306406 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0299672 |
| GSE1 | Gse1 coiled-coil protein | -0.0292189 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0285994 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0282456 |
| RPLP0 | ribosomal protein, large, P0 | -0.0282143 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.027821 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0276825 |
| EGFR | epidermal growth factor receptor | -0.027525 |
| HMGB1 | high mobility group box 1 | -0.0274761 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0272806 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0272298 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0266778 |
| DEK | DEK proto-oncogene | -0.0266725 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0264165 |
| FUS | FUS RNA binding protein | -0.0262704 |
| RPS24 | ribosomal protein S24 | -0.0256527 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0255655 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0252443 |
| TPX2 | TPX2, microtubule-associated | -0.0252163 |
| RPS21 | ribosomal protein S21 | -0.0252149 |
| RPL31 | ribosomal protein L31 | -0.0251984 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0248327 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0241349 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0240835 |
| RPS13 | ribosomal protein S13 | -0.024 |
| TUBA1B | tubulin, alpha 1b | -0.0237917 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.023411 |
| RPL36 | ribosomal protein L36 | -0.0232093 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0230416 |
| ZNF438 | zinc finger protein 438 | -0.0229792 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0229703 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0229389 |
| RPL9 | ribosomal protein L9 | -0.0228281 |
| RPS23 | ribosomal protein S23 | -0.0226374 |
| HJURP | Holliday junction recognition protein | -0.0225808 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0224555 |
| RRM2 | ribonucleotide reductase M2 | -0.0221529 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0221115 |
| EMP3 | epithelial membrane protein 3 | -0.0217539 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0217222 |
| S100A9 | S100 calcium binding protein A9 | -0.0211519 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0210441 |
| TUBB | tubulin, beta class I | -0.0208978 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0205776 |
| TPI1 | triosephosphate isomerase 1 | -0.0202322 |
| RPLP2 | ribosomal protein, large, P2 | -0.0201511 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0201272 |
| COMMD10 | COMM domain containing 10 | -0.0199671 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.019734 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0195178 |
| S100A10 | S100 calcium binding protein A10 | -0.0194634 |
| RPL8 | ribosomal protein L8 | -0.0192465 |
| ANLN | anillin, actin binding protein | -0.0191762 |
| NOP56 | NOP56 ribonucleoprotein | -0.0188925 |
| MYL12B | myosin, light chain 12B, regulatory | -0.018774 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0187572 |
| RPS11 | ribosomal protein S11 | -0.018746 |
