| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetazolamide perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Acetazolamide_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.140615 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0948378 |
| OGA | O-GlcNAcase | 0.0900566 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0756584 |
| GOLGA4 | golgin A4 | 0.0750816 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0660225 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0626081 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0619019 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0593069 |
| ATP13A3 | ATPase type 13A3 | 0.0561564 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0545319 |
| SPAG9 | sperm associated antigen 9 | 0.0534921 |
| FNIP1 | folliculin interacting protein 1 | 0.0488626 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0473888 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0464125 |
| HELZ | helicase with zinc finger | 0.0460655 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0445652 |
| SERINC1 | serine incorporator 1 | 0.0443302 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0437942 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0432766 |
| MATR3 | matrin 3 | 0.0424509 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0403647 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0384195 |
| APP | amyloid beta (A4) precursor protein | 0.038093 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0379544 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0369028 |
| CADM1 | cell adhesion molecule 1 | 0.0355507 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0353474 |
| RLF | rearranged L-myc fusion | 0.0335629 |
| ADM | adrenomedullin | 0.0330235 |
| SDC4 | syndecan 4 | 0.0324206 |
| RBM39 | RNA binding motif protein 39 | 0.0323143 |
| ARRDC3 | arrestin domain containing 3 | 0.0322293 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0313318 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0312163 |
| FMNL2 | formin-like 2 | 0.0296821 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0295822 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0286906 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0283673 |
| TEX10 | testis expressed 10 | 0.0283043 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0279421 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0274074 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0273925 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.027258 |
| NAV2 | neuron navigator 2 | 0.0271008 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0270482 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0266394 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0266301 |
| AFDN | afadin, adherens junction formation factor | 0.0260718 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.025915 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0258523 |
| RPL14 | ribosomal protein L14 | 0.0254849 |
| MSN | moesin | 0.0253697 |
| RYBP | RING1 and YY1 binding protein | 0.0252351 |
| ABI1 | abl-interactor 1 | 0.0251174 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0250421 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0248976 |
| DUSP10 | dual specificity phosphatase 10 | 0.0248732 |
| RND3 | Rho family GTPase 3 | 0.0245598 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | 0.0243093 |
| PCBP2 | poly(rC) binding protein 2 | 0.0240778 |
| MYOF | myoferlin | 0.0238741 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0236101 |
| SET | SET nuclear proto-oncogene | 0.0234195 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0227017 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0226493 |
| CRY1 | cryptochrome circadian clock 1 | 0.0225344 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0224681 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0223253 |
| RPL3 | ribosomal protein L3 | 0.0222499 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0221642 |
| CCDC93 | coiled-coil domain containing 93 | 0.0220103 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.021965 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0218248 |
| PUM2 | pumilio RNA-binding family member 2 | 0.021732 |
| COPA | coatomer protein complex, subunit alpha | 0.0216573 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.021489 |
| USP37 | ubiquitin specific peptidase 37 | 0.021294 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0211406 |
| TPR | translocated promoter region, nuclear basket protein | 0.0211158 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0209658 |
| WAC | WW domain containing adaptor with coiled-coil | 0.02071 |
| ANLN | anillin, actin binding protein | 0.0206693 |
| PDE10A | phosphodiesterase 10A | 0.0205696 |
| SAFB2 | scaffold attachment factor B2 | 0.0201727 |
| RAB7A | RAB7A, member RAS oncogene family | 0.020159 |
| MIS18BP1 | MIS18 binding protein 1 | 0.020054 |
| DENND5A | DENN/MADD domain containing 5A | 0.0198152 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0196596 |
| NEK7 | NIMA-related kinase 7 | 0.0195793 |
| NGLY1 | N-glycanase 1 | 0.0195469 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0192098 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0190744 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0189659 |
| RBM33 | RNA binding motif protein 33 | 0.0189437 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0188114 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0187915 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0187389 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0187181 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0184444 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.158227 |
| VIM | vimentin | -0.152868 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.149806 |
| HLA-B | major histocompatibility complex, class I, B | -0.141926 |
| FRMD4A | FERM domain containing 4A | -0.139844 |
| GLIS3 | GLIS family zinc finger 3 | -0.13373 |
| FTL | ferritin, light polypeptide | -0.112153 |
| BICC1 | BicC family RNA binding protein 1 | -0.109902 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.106908 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.103809 |
| EXT1 | exostosin glycosyltransferase 1 | -0.102021 |
| TMSB10 | thymosin beta 10 | -0.0846013 |
| NDRG1 | N-myc downstream regulated 1 | -0.0814033 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0808268 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0792409 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0771675 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0757724 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0740669 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0641955 |
| EGR1 | early growth response 1 | -0.0612735 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0612001 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0572234 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0569411 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0565416 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.056146 |
| RPL35A | ribosomal protein L35a | -0.0558064 |
| CD44 | CD44 molecule (Indian blood group) | -0.0551719 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0548133 |
| HMGA2 | high mobility group AT-hook 2 | -0.0544047 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0542054 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0537826 |
| CTSD | cathepsin D | -0.0529299 |
| HLA-A | major histocompatibility complex, class I, A | -0.052582 |
| ATXN1 | ataxin 1 | -0.0521242 |
| NAV1 | neuron navigator 1 | -0.0507684 |
| ASPH | aspartate beta-hydroxylase | -0.0502993 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0479803 |
| RPS24 | ribosomal protein S24 | -0.0477174 |
| RNF213 | ring finger protein 213 | -0.047267 |
| EGFR | epidermal growth factor receptor | -0.0460639 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0458752 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0454624 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0444883 |
| COL1A1 | collagen, type I, alpha 1 | -0.0442154 |
| DST | dystonin | -0.0436539 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0430401 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0420787 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.041577 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0412829 |
| RAD51B | RAD51 paralog B | -0.0404905 |
| DIAPH2 | diaphanous-related formin 2 | -0.0400593 |
| TPM1 | tropomyosin 1 (alpha) | -0.0397342 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0385345 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0379338 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0375073 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0364479 |
| MX1 | MX dynamin-like GTPase 1 | -0.0363329 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0363005 |
| IER3 | immediate early response 3 | -0.0362242 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0361818 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0361538 |
| RPS23 | ribosomal protein S23 | -0.0360348 |
| HMGA1 | high mobility group AT-hook 1 | -0.0360191 |
| TAPBP | TAP binding protein (tapasin) | -0.035798 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0356013 |
| RAI14 | retinoic acid induced 14 | -0.0355173 |
| UTRN | utrophin | -0.0349344 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0344013 |
| FOXP1 | forkhead box P1 | -0.0342333 |
| RIGI | RNA sensor RIG-I | -0.0341982 |
| ACTG1 | actin gamma 1 | -0.0339533 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0337899 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0337615 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0337091 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0331847 |
| RPLP1 | ribosomal protein, large, P1 | -0.0331654 |
| CALR | calreticulin | -0.0326024 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0325088 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0315209 |
| RPL23 | ribosomal protein L23 | -0.0311669 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0311556 |
| TENM2 | teneurin transmembrane protein 2 | -0.0306227 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0306062 |
| TPM4 | tropomyosin 4 | -0.0305233 |
| MAP1B | microtubule-associated protein 1B | -0.030336 |
| BPTF | bromodomain PHD finger transcription factor | -0.0303282 |
| NRP1 | neuropilin 1 | -0.0302884 |
| MT2A | metallothionein 2A | -0.0300352 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0299015 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0298115 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0294086 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0288914 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0285193 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0284231 |
| RRBP1 | ribosome binding protein 1 | -0.0282805 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0282134 |
| SMYD3 | SET and MYND domain containing 3 | -0.0280649 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0280192 |
| SYNJ2 | synaptojanin 2 | -0.0279202 |
| RPS6 | ribosomal protein S6 | -0.0276959 |
