| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetazolamide perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Acetazolamide_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0861699 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0685426 |
| ZNF292 | zinc finger protein 292 | 0.0560783 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.052834 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0496805 |
| SPAG9 | sperm associated antigen 9 | 0.049374 |
| OGA | O-GlcNAcase | 0.0463183 |
| FAM13A | family with sequence similarity 13, member A | 0.042585 |
| MATR3 | matrin 3 | 0.041443 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0413101 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0409213 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0401946 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0389423 |
| TXNIP | thioredoxin interacting protein | 0.0388487 |
| RPS6 | ribosomal protein S6 | 0.0387044 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.038019 |
| PTMA | prothymosin, alpha | 0.0375289 |
| SLTM | SAFB-like, transcription modulator | 0.0373536 |
| CD44 | CD44 molecule (Indian blood group) | 0.0372185 |
| LMO7 | LIM domain 7 | 0.0368865 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0368648 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0353791 |
| ANXA2 | annexin A2 | 0.034056 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0336719 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0331244 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0330568 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0328714 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0325837 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0324766 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0322047 |
| ANLN | anillin, actin binding protein | 0.0315093 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0314299 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0310809 |
| SUCO | SUN domain containing ossification factor | 0.0310625 |
| RYBP | RING1 and YY1 binding protein | 0.030555 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0300273 |
| SP100 | SP100 nuclear antigen | 0.0298213 |
| ATP13A3 | ATPase type 13A3 | 0.0296814 |
| RBM39 | RNA binding motif protein 39 | 0.0295565 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0294481 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0292444 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0287749 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0287186 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0285635 |
| TPR | translocated promoter region, nuclear basket protein | 0.0285626 |
| FTL | ferritin, light polypeptide | 0.0284145 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0283111 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0282331 |
| GOLGA4 | golgin A4 | 0.0281313 |
| RPL23 | ribosomal protein L23 | 0.0280944 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0280942 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.027162 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.026571 |
| ABLIM1 | actin binding LIM protein 1 | 0.0261413 |
| ABI1 | abl-interactor 1 | 0.026039 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0259621 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.02592 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0254626 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0253401 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0253038 |
| RPS3 | ribosomal protein S3 | 0.0252859 |
| RPL35A | ribosomal protein L35a | 0.0252146 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0252083 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0251574 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0251475 |
| INSIG1 | insulin induced gene 1 | 0.0250914 |
| FMNL2 | formin-like 2 | 0.0247147 |
| RANBP2 | RAN binding protein 2 | 0.0246411 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0244817 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0244162 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0243993 |
| SEPTIN10 | septin 10 | 0.0243154 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0241914 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0240637 |
| FAM162A | family with sequence similarity 162, member A | 0.0240463 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0239498 |
| CCDC88A | coiled-coil domain containing 88A | 0.0238594 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.0238101 |
| NOP58 | NOP58 ribonucleoprotein | 0.0234117 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0233766 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0230646 |
| ACO2 | aconitase 2, mitochondrial | 0.0229005 |
| TJP1 | tight junction protein 1 | 0.0228562 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0228238 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0228116 |
| PRPF18 | pre-mRNA processing factor 18 | 0.0227338 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0227226 |
| RPL9 | ribosomal protein L9 | 0.0227108 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.022604 |
| RPL7 | ribosomal protein L7 | 0.0225922 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0225001 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0224683 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0222632 |
| WASF2 | WAS protein family, member 2 | 0.0220426 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0218171 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0217885 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0217552 |
| TUBB | tubulin, beta class I | 0.0217208 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.021718 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0217031 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.307594 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.241096 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.117437 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.112784 |
| CDH13 | cadherin 13 | -0.110789 |
| EGFR | epidermal growth factor receptor | -0.109519 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0956371 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0948628 |
| MAP1B | microtubule-associated protein 1B | -0.0806243 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0760639 |
| COL5A1 | collagen, type V, alpha 1 | -0.0741861 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0739861 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0734909 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0728618 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0668094 |
| COL1A2 | collagen, type I, alpha 2 | -0.0665948 |
| NDRG1 | N-myc downstream regulated 1 | -0.0654625 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0629128 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.061992 |
| B2M | beta-2-microglobulin | -0.0614217 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0611995 |
| LOXL2 | lysyl oxidase-like 2 | -0.0585322 |
| VEGFC | vascular endothelial growth factor C | -0.0569244 |
| CALD1 | caldesmon 1 | -0.0550725 |
| VEGFA | vascular endothelial growth factor A | -0.0547793 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0500598 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0474175 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0473411 |
| HLA-B | major histocompatibility complex, class I, B | -0.0460556 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0456575 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0456167 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0454561 |
| NRXN3 | neurexin 3 | -0.0436843 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0434895 |
| PRSS23 | protease, serine, 23 | -0.0430711 |
| LDHA | lactate dehydrogenase A | -0.0427128 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0426692 |
| HLA-C | major histocompatibility complex, class I, C | -0.0421497 |
| POTEF | POTE ankyrin domain family, member F | -0.0410713 |
| TNS3 | tensin 3 | -0.0407166 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0406597 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0406383 |
| EXOC4 | exocyst complex component 4 | -0.040622 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0401757 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0395611 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0389311 |
| CLINT1 | clathrin interactor 1 | -0.0389039 |
| CDK6 | cyclin-dependent kinase 6 | -0.0385751 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0383279 |
| CDK13 | cyclin-dependent kinase 13 | -0.0378001 |
| GLIS3 | GLIS family zinc finger 3 | -0.0375262 |
| PRKCA | protein kinase C, alpha | -0.0374285 |
| KAZN | kazrin, periplakin interacting protein | -0.0371406 |
| SEC24D | SEC24 family member D | -0.0370416 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0364814 |
| STC1 | stanniocalcin 1 | -0.03596 |
| NAV1 | neuron navigator 1 | -0.0356438 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0355386 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0352569 |
| FLNA | filamin A, alpha | -0.0351269 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0347803 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0345242 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0341078 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.03402 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0330508 |
| CALU | calumenin | -0.0328181 |
| C1D | C1D nuclear receptor corepressor | -0.0320631 |
| MT2A | metallothionein 2A | -0.0310927 |
| IL6ST | interleukin 6 signal transducer | -0.0306516 |
| INHBA | inhibin, beta A | -0.0303236 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0300316 |
| RASAL2 | RAS protein activator like 2 | -0.0300218 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0299359 |
| SMYD3 | SET and MYND domain containing 3 | -0.0297196 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0295828 |
| MAP4 | microtubule-associated protein 4 | -0.0288055 |
| TMF1 | TATA element modulatory factor 1 | -0.0286192 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0285938 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0284045 |
| KRIT1 | KRIT1, ankyrin repeat containing | -0.0276614 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0275767 |
| PGM3 | phosphoglucomutase 3 | -0.0268257 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0268244 |
| IL6 | interleukin 6 | -0.0265998 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0264487 |
| MYO10 | myosin X | -0.0263952 |
| HMGA2 | high mobility group AT-hook 2 | -0.0262456 |
| NABP1 | nucleic acid binding protein 1 | -0.0262231 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0262218 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0261298 |
| AHNAK | AHNAK nucleoprotein | -0.0260181 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0259281 |
| EFNA5 | ephrin-A5 | -0.0258671 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0256229 |
| LOX | lysyl oxidase | -0.0251845 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0250469 |
| MYOF | myoferlin | -0.0249009 |
| COL1A1 | collagen, type I, alpha 1 | -0.024666 |
| BSG | basigin (Ok blood group) | -0.0245219 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0244263 |
