| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetazolamide perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Acetazolamide_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0844362 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0786611 |
| OGA | O-GlcNAcase | 0.0757989 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0747374 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0737266 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0629909 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0568599 |
| GOLGA4 | golgin A4 | 0.0565538 |
| SUCO | SUN domain containing ossification factor | 0.0523724 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0521569 |
| TPR | translocated promoter region, nuclear basket protein | 0.0518216 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0512774 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0464541 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.046294 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0453284 |
| RNF145 | ring finger protein 145 | 0.0425835 |
| VMP1 | vacuole membrane protein 1 | 0.0417352 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0405045 |
| COPA | coatomer protein complex, subunit alpha | 0.0394622 |
| COG5 | component of oligomeric golgi complex 5 | 0.0394164 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0393751 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0392025 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0390889 |
| WDR26 | WD repeat domain 26 | 0.038242 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.037868 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0378032 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0373894 |
| RANBP2 | RAN binding protein 2 | 0.0367162 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0365949 |
| RAB18 | RAB18, member RAS oncogene family | 0.035976 |
| CUL3 | cullin 3 | 0.0339985 |
| ETNK1 | ethanolamine kinase 1 | 0.0338725 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0335703 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0333578 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0325037 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0322154 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.03181 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0317515 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0301218 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0299538 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0299373 |
| NUP58 | nucleoporin 58 | 0.0296525 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.029386 |
| RPL26 | ribosomal protein L26 | 0.0291443 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0290696 |
| CDC73 | cell division cycle 73 | 0.029039 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0289044 |
| WDR45B | WD repeat domain 45B | 0.0288671 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0285133 |
| AFDN | afadin, adherens junction formation factor | 0.0284423 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0281658 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0280936 |
| INSIG2 | insulin induced gene 2 | 0.02784 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0271313 |
| SEPTIN7 | septin 7 | 0.0270768 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0269347 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0268637 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0266115 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0265845 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0263922 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0263386 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0259263 |
| CEP350 | centrosomal protein 350kDa | 0.0257531 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0255693 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0253001 |
| CANX | calnexin | 0.0252472 |
| MATR3 | matrin 3 | 0.0251934 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0251643 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0250521 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0247994 |
| ARF4 | ADP-ribosylation factor 4 | 0.024489 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0242778 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0241959 |
| ATL2 | atlastin GTPase 2 | 0.0240656 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0239991 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0237718 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0236427 |
| NEK7 | NIMA-related kinase 7 | 0.0236085 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0235969 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0235611 |
| USP3 | ubiquitin specific peptidase 3 | 0.0235096 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0234832 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0232712 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0232673 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0232521 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.023199 |
| CLINT1 | clathrin interactor 1 | 0.0231923 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0231882 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0231346 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0231271 |
| RAD21 | RAD21 homolog (S. pombe) | 0.023027 |
| CAB39 | calcium binding protein 39 | 0.022974 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.022842 |
| SLAIN2 | SLAIN motif family, member 2 | 0.0228382 |
| SECISBP2L | SECIS binding protein 2-like | 0.0228212 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.022805 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0225288 |
| CDC27 | cell division cycle 27 | 0.0224073 |
| FBXW11 | F-box and WD repeat domain containing 11 | 0.0222563 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0222538 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.236072 |
| FN1 | fibronectin 1 | -0.226889 |
| HMGA2 | high mobility group AT-hook 2 | -0.18764 |
| NDRG1 | N-myc downstream regulated 1 | -0.160311 |
| ASPH | aspartate beta-hydroxylase | -0.117477 |
| ITGA1 | integrin, alpha 1 | -0.112107 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.107324 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.100584 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.10048 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0872674 |
| SYT1 | synaptotagmin I | -0.085258 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0797051 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0787866 |
| LMNA | lamin A/C | -0.0773805 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0728575 |
| STC2 | stanniocalcin 2 | -0.0680188 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0668382 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0646503 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0632014 |
| SQSTM1 | sequestosome 1 | -0.0623632 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.057688 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0562665 |
| HLA-B | major histocompatibility complex, class I, B | -0.0555049 |
| MAP1B | microtubule-associated protein 1B | -0.054779 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0545739 |
| GLIS3 | GLIS family zinc finger 3 | -0.0520792 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0519888 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0517901 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0509242 |
| TMSB10 | thymosin beta 10 | -0.0489734 |
| RAI14 | retinoic acid induced 14 | -0.0486356 |
| ACTG1 | actin gamma 1 | -0.0482232 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0482048 |
| FTL | ferritin, light polypeptide | -0.0467106 |
| POTEF | POTE ankyrin domain family, member F | -0.0448088 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0444509 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0444337 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0435035 |
| RPL35A | ribosomal protein L35a | -0.0427183 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0409152 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0404549 |
| HMGA1 | high mobility group AT-hook 1 | -0.0403359 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0401312 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0392348 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0389504 |
| LOXL2 | lysyl oxidase-like 2 | -0.0388704 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0388134 |
| S100A6 | S100 calcium binding protein A6 | -0.0387045 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0386579 |
| NAV2 | neuron navigator 2 | -0.0385909 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0385735 |
| EFNA5 | ephrin-A5 | -0.0384432 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0384165 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0383746 |
| PKM | pyruvate kinase, muscle | -0.0379653 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.03785 |
| EGR1 | early growth response 1 | -0.0369518 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0368947 |
| RNF213 | ring finger protein 213 | -0.0367302 |
| S100A10 | S100 calcium binding protein A10 | -0.036682 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0346454 |
| GPC6 | glypican 6 | -0.0346298 |
| EMP1 | epithelial membrane protein 1 | -0.0341213 |
| IFI44L | interferon-induced protein 44-like | -0.0336189 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0333753 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0320957 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0314307 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0312946 |
| SVIL | supervillin | -0.0309184 |
| PTK2 | protein tyrosine kinase 2 | -0.030765 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0305049 |
| MCL1 | myeloid cell leukemia 1 | -0.0304664 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.030465 |
| ATXN1 | ataxin 1 | -0.0304445 |
| EXOC4 | exocyst complex component 4 | -0.0304324 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0302868 |
| DUSP6 | dual specificity phosphatase 6 | -0.0299771 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0299575 |
| TGFA | transforming growth factor, alpha | -0.0295562 |
| PLIN2 | perilipin 2 | -0.0295142 |
| IER3 | immediate early response 3 | -0.0295048 |
| EZR | ezrin | -0.0291751 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0291164 |
| RPL38 | ribosomal protein L38 | -0.0290036 |
| VEGFA | vascular endothelial growth factor A | -0.0289927 |
| RAD51B | RAD51 paralog B | -0.0287548 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0286462 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0285485 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.028449 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0283173 |
| ETV1 | ets variant 1 | -0.0280527 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0278716 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0276114 |
| TENM4 | teneurin transmembrane protein 4 | -0.0274719 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0274016 |
| TMEM156 | transmembrane protein 156 | -0.0272131 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0267289 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | -0.026642 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0265826 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0264928 |
