| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetohexamide perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Acetohexamide_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.199221 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0889048 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0693361 |
| MYADM | myeloid-associated differentiation marker | 0.0692446 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0679431 |
| NDRG1 | N-myc downstream regulated 1 | 0.0666884 |
| FLNB | filamin B, beta | 0.0647267 |
| DST | dystonin | 0.0638794 |
| CDH13 | cadherin 13 | 0.062894 |
| DCLK2 | doublecortin-like kinase 2 | 0.0618308 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0610891 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0595467 |
| HDAC9 | histone deacetylase 9 | 0.0579743 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0536462 |
| MT2A | metallothionein 2A | 0.053291 |
| EGFR | epidermal growth factor receptor | 0.0528547 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0524634 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0522324 |
| MAP1B | microtubule-associated protein 1B | 0.0516571 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.051084 |
| TPM3 | tropomyosin 3 | 0.0506546 |
| MSN | moesin | 0.0503803 |
| POTEF | POTE ankyrin domain family, member F | 0.050356 |
| ASPH | aspartate beta-hydroxylase | 0.0481941 |
| MYOF | myoferlin | 0.0464396 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0445876 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0439005 |
| CENPF | centromere protein F, 350/400kDa | 0.0438269 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0427567 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0410687 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0399048 |
| FOSL1 | FOS-like antigen 1 | 0.039281 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0389149 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0383662 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0381995 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0376145 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0375319 |
| RUNX1 | runt-related transcription factor 1 | 0.0365948 |
| RTN4 | reticulon 4 | 0.0364671 |
| FLNA | filamin A, alpha | 0.0361724 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0354065 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0350713 |
| CD44 | CD44 molecule (Indian blood group) | 0.0349994 |
| TAGLN2 | transgelin 2 | 0.0344639 |
| PFN1 | profilin 1 | 0.0341303 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0338366 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0336349 |
| ARFGEF3 | ARFGEF family member 3 | 0.033064 |
| SEPTIN9 | septin 9 | 0.032959 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0329393 |
| DEPP1 | DEPP autophagy regulator 1 | 0.0328522 |
| C1D | C1D nuclear receptor corepressor | 0.0321098 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0320793 |
| VEGFA | vascular endothelial growth factor A | 0.0320534 |
| PCBP2 | poly(rC) binding protein 2 | 0.0315168 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.031452 |
| MNT | MAX network transcriptional repressor | 0.0313608 |
| DSPP | dentin sialophosphoprotein | 0.0312619 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0307677 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0303039 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0291003 |
| RND3 | Rho family GTPase 3 | 0.0289771 |
| NOTCH2 | notch 2 | 0.0288484 |
| COPA | coatomer protein complex, subunit alpha | 0.0288463 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.028709 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0286973 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0277224 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0277092 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0275251 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.027469 |
| VMP1 | vacuole membrane protein 1 | 0.0273182 |
| FAM107B | family with sequence similarity 107, member B | 0.0272668 |
| TAOK1 | TAO kinase 1 | 0.0271888 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0271216 |
| AXL | AXL receptor tyrosine kinase | 0.0270727 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0270545 |
| PFKP | phosphofructokinase, platelet | 0.0267379 |
| SEPTIN7 | septin 7 | 0.0267375 |
| ERBIN | erbb2 interacting protein | 0.0265797 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0265292 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0264632 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0264455 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0263565 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0263428 |
| FN1 | fibronectin 1 | 0.0261814 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0259806 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0256569 |
| TLN1 | talin 1 | 0.0252423 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0251224 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0248291 |
| FNIP1 | folliculin interacting protein 1 | 0.024829 |
| MEF2D | myocyte enhancer factor 2D | 0.0247449 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0246831 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0246628 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0246404 |
| PTK2 | protein tyrosine kinase 2 | 0.0246279 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0245027 |
| ZNF292 | zinc finger protein 292 | 0.0244693 |
| CYTH3 | cytohesin 3 | 0.0243193 |
| ZNF148 | zinc finger protein 148 | 0.0242148 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.191994 |
| FBN1 | fibrillin 1 | -0.138324 |
| VIM | vimentin | -0.131798 |
| COL3A1 | collagen, type III, alpha 1 | -0.116318 |
| TMSB10 | thymosin beta 10 | -0.114369 |
| THBS2 | thrombospondin 2 | -0.104557 |
| COL1A2 | collagen, type I, alpha 2 | -0.101467 |
| PTMA | prothymosin, alpha | -0.0665292 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0622787 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0620081 |
| AHNAK | AHNAK nucleoprotein | -0.0570833 |
| HLA-B | major histocompatibility complex, class I, B | -0.0557946 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.053961 |
| TMSB4X | thymosin beta 4, X-linked | -0.0538308 |
| S100A10 | S100 calcium binding protein A10 | -0.052261 |
| CAVIN1 | caveolae associated protein 1 | -0.0521906 |
| PRSS23 | protease, serine, 23 | -0.0515727 |
| LOXL2 | lysyl oxidase-like 2 | -0.0505718 |
| SQSTM1 | sequestosome 1 | -0.0499666 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0469518 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0464019 |
| HLA-C | major histocompatibility complex, class I, C | -0.0447114 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0445398 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0433801 |
| CCND1 | cyclin D1 | -0.0428496 |
| GPC6 | glypican 6 | -0.0419972 |
| HLA-E | major histocompatibility complex, class I, E | -0.0413494 |
| RPS24 | ribosomal protein S24 | -0.0401576 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0395602 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0395025 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0390439 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0388009 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0380735 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0378077 |
| MX2 | MX dynamin-like GTPase 2 | -0.0362413 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.035446 |
| FRMD5 | FERM domain containing 5 | -0.0349083 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0346233 |
| AUTS2 | autism susceptibility candidate 2 | -0.0338181 |
| ACTG1 | actin gamma 1 | -0.0336255 |
| FRMD4A | FERM domain containing 4A | -0.0332809 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0328343 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0327359 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0326568 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0315475 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0309023 |
| MEIS2 | Meis homeobox 2 | -0.0303172 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0297721 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0296277 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0295293 |
| COL5A2 | collagen, type V, alpha 2 | -0.0293502 |
| RAB1A | RAB1A, member RAS oncogene family | -0.029281 |
| S100A6 | S100 calcium binding protein A6 | -0.029273 |
| CTSB | cathepsin B | -0.0291387 |
| ATP13A3 | ATPase type 13A3 | -0.0290303 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0285979 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0285596 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0285321 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0276088 |
| KIFAP3 | kinesin-associated protein 3 | -0.0265237 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0264763 |
| SUCNR1 | succinate receptor 1 | -0.026466 |
| LMNA | lamin A/C | -0.0262671 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0257507 |
| RPL35A | ribosomal protein L35a | -0.0257331 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0256362 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0254709 |
| S100A4 | S100 calcium binding protein A4 | -0.0254463 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0254436 |
| LDHA | lactate dehydrogenase A | -0.025266 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0250204 |
| WTAP | Wilms tumor 1 associated protein | -0.0248236 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0247592 |
| RIGI | RNA sensor RIG-I | -0.0243515 |
| GASK1B | golgi associated kinase 1B | -0.0240566 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0238821 |
| SPAG9 | sperm associated antigen 9 | -0.0237185 |
| GNAS | GNAS complex locus | -0.023391 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0231537 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0230128 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0227678 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0226946 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0225271 |
| ARF1 | ADP-ribosylation factor 1 | -0.022399 |
| CD63 | CD63 molecule | -0.0223728 |
| INSIG1 | insulin induced gene 1 | -0.0223586 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0222504 |
| H3-3B | H3.3 histone B | -0.0221947 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0221672 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0221404 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0221306 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0220625 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0219249 |
| LRRC49 | leucine rich repeat containing 49 | -0.0219081 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0218924 |
| KLF6 | Kruppel-like factor 6 | -0.0217224 |
| PRRX1 | paired related homeobox 1 | -0.0215714 |
| B2M | beta-2-microglobulin | -0.0214207 |
| TMOD1 | tropomodulin 1 | -0.0210921 |
| RRM2 | ribonucleotide reductase M2 | -0.0206177 |
