| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetohexamide perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Acetohexamide_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.124315 |
| NLGN1 | neuroligin 1 | 0.111259 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0976027 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0891793 |
| HMGA2 | high mobility group AT-hook 2 | 0.0760662 |
| PCDH7 | protocadherin 7 | 0.0715081 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0659512 |
| MMP12 | matrix metallopeptidase 12 | 0.0646431 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.063987 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.056013 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0531766 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0519263 |
| ATP11A | ATPase, class VI, type 11A | 0.0491155 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0488362 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.047673 |
| AHNAK | AHNAK nucleoprotein | 0.0464869 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0463333 |
| TXNRD1 | thioredoxin reductase 1 | 0.0455963 |
| TENM3 | teneurin transmembrane protein 3 | 0.0430767 |
| DST | dystonin | 0.0416067 |
| MED13L | mediator complex subunit 13-like | 0.0410912 |
| YAP1 | Yes-associated protein 1 | 0.040993 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0407247 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.040344 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0397665 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0384385 |
| RPL19 | ribosomal protein L19 | 0.0378555 |
| ZNF638 | zinc finger protein 638 | 0.0369703 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0365887 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0365285 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0361492 |
| GPHN | gephyrin | 0.0352907 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0350289 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0348132 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0343103 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0341749 |
| CMIP | c-Maf inducing protein | 0.0334452 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.032804 |
| RPLP1 | ribosomal protein, large, P1 | 0.0323613 |
| ASPH | aspartate beta-hydroxylase | 0.0311593 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0309895 |
| INTS6 | integrator complex subunit 6 | 0.0308378 |
| RPL35A | ribosomal protein L35a | 0.0303236 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0302653 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0302627 |
| MPG | N-methylpurine-DNA glycosylase | 0.0298097 |
| EZR | ezrin | 0.0294602 |
| RPL23 | ribosomal protein L23 | 0.0284315 |
| EXOC6B | exocyst complex component 6B | 0.0280011 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0279433 |
| FTL | ferritin, light polypeptide | 0.0278312 |
| RPS23 | ribosomal protein S23 | 0.0275334 |
| NEBL | nebulette | 0.0272142 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0269408 |
| RPS29 | ribosomal protein S29 | 0.0268715 |
| TGM2 | transglutaminase 2 | 0.0266568 |
| PTK2 | protein tyrosine kinase 2 | 0.0260839 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0258927 |
| EFNA5 | ephrin-A5 | 0.0257885 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0257504 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0257212 |
| EGFR | epidermal growth factor receptor | 0.0256865 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.025574 |
| PARD3 | par-3 family cell polarity regulator | 0.0254277 |
| CCN2 | cellular communication network factor 2 | 0.0251496 |
| RPL3 | ribosomal protein L3 | 0.024886 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0247651 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0245713 |
| TMSB10 | thymosin beta 10 | 0.0243525 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0241648 |
| OXR1 | oxidation resistance 1 | 0.0240205 |
| FHIT | fragile histidine triad | 0.0237746 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0236664 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0235491 |
| RPL4 | ribosomal protein L4 | 0.0235128 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0233332 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0232548 |
| NEK7 | NIMA-related kinase 7 | 0.023189 |
| SETD5 | SET domain containing 5 | 0.0231865 |
| RPL13A | ribosomal protein L13a | 0.0231422 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0230204 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0229197 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.022887 |
| SYT1 | synaptotagmin I | 0.0226701 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0224213 |
| RPS6 | ribosomal protein S6 | 0.0222854 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.022009 |
| CEP112 | centrosomal protein 112kDa | 0.0219532 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0216633 |
| TBCA | tubulin folding cofactor A | 0.0216454 |
| NRXN3 | neurexin 3 | 0.0216357 |
| MAP4 | microtubule-associated protein 4 | 0.0214549 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0214151 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0213706 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 0.0213246 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0212181 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0211725 |
| KLC1 | kinesin light chain 1 | 0.021147 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0211029 |
| SMYD3 | SET and MYND domain containing 3 | 0.0210981 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.13363 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.133292 |
| TPI1 | triosephosphate isomerase 1 | -0.0619064 |
| TUBA1B | tubulin, alpha 1b | -0.0547786 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0470045 |
| ACTG1 | actin gamma 1 | -0.0395431 |
| LDHA | lactate dehydrogenase A | -0.037699 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0358824 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0335731 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0329252 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.029906 |
| HMGA1 | high mobility group AT-hook 1 | -0.0283442 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0263444 |
| KIF18B | kinesin family member 18B | -0.0262143 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0256296 |
| EGR1 | early growth response 1 | -0.025563 |
| LDHB | lactate dehydrogenase B | -0.0248091 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0247925 |
| RPLP0 | ribosomal protein, large, P0 | -0.0246717 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0245899 |
| POTEF | POTE ankyrin domain family, member F | -0.0241313 |
| TUBA1C | tubulin, alpha 1c | -0.0232656 |
| PFN1 | profilin 1 | -0.0228575 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0224197 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0221729 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0218944 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0206501 |
| CBX3 | chromobox homolog 3 | -0.0206488 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0196165 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0191927 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0191818 |
| H3-3B | H3.3 histone B | -0.0190113 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0188028 |
| CENPF | centromere protein F, 350/400kDa | -0.0187087 |
| PRDX1 | peroxiredoxin 1 | -0.0185547 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0182323 |
| HDGF | hepatoma-derived growth factor | -0.0182194 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0179369 |
| VIM | vimentin | -0.0177567 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0173139 |
| NAV3 | neuron navigator 3 | -0.0170026 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.016712 |
| MAP1B | microtubule-associated protein 1B | -0.0167093 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0166639 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0164297 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0159709 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.015931 |
| SET | SET nuclear proto-oncogene | -0.0155258 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0155239 |
| TMEM41B | transmembrane protein 41B | -0.0154502 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.015165 |
| RPS24 | ribosomal protein S24 | -0.0149112 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0146673 |
| TMEM123 | transmembrane protein 123 | -0.0142711 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0141743 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.014051 |
| MYADM | myeloid-associated differentiation marker | -0.0138163 |
| RPL26 | ribosomal protein L26 | -0.0137023 |
| TUBB | tubulin, beta class I | -0.0136869 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0135862 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | -0.0135388 |
| NDC80 | NDC80 kinetochore complex component | -0.0134248 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0132283 |
| RTN4 | reticulon 4 | -0.0132238 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0130079 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0129038 |
| TCERG1 | transcription elongation regulator 1 | -0.0128818 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.0125749 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -0.0125172 |
| TPM4 | tropomyosin 4 | -0.0124243 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0123531 |
| IER2 | immediate early response 2 | -0.0123444 |
| TBK1 | TANK-binding kinase 1 | -0.0122833 |
| TPX2 | TPX2, microtubule-associated | -0.0122376 |
| ACLY | ATP citrate lyase | -0.0122294 |
| XPOT | exportin, tRNA | -0.0121543 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0117836 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0116615 |
| RPS21 | ribosomal protein S21 | -0.0116552 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0116042 |
| ANXA1 | annexin A1 | -0.0115721 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0115716 |
| RRM2 | ribonucleotide reductase M2 | -0.011471 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0114157 |
| PTMS | parathymosin | -0.0113228 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0112926 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0111417 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | -0.0110241 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | -0.0110193 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0110003 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0107 |
| MTPN | myotrophin | -0.0105516 |
| USP1 | ubiquitin specific peptidase 1 | -0.010532 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0105019 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0104516 |
| RECQL | RecQ helicase-like | -0.0104102 |
| SLC36A4 | solute carrier family 36 (proton/amino acid symporter), member 4 | -0.0103997 |
| GCG | glucagon | -0.0103416 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.0102547 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | -0.0102239 |
