| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetohexamide perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Acetohexamide_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.214725 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.117384 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.112466 |
| VEGFA | vascular endothelial growth factor A | 0.110972 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.110365 |
| FNDC3B | fibronectin type III domain containing 3B | 0.106003 |
| CD44 | CD44 molecule (Indian blood group) | 0.0815989 |
| HMGA2 | high mobility group AT-hook 2 | 0.0620079 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0541417 |
| NAV2 | neuron navigator 2 | 0.0538181 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0530193 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0517376 |
| MRTFA | myocardin related transcription factor A | 0.050834 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0500919 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0439621 |
| RIGI | RNA sensor RIG-I | 0.043046 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0427305 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0426557 |
| SPAG9 | sperm associated antigen 9 | 0.0424173 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0421847 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.041393 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0410188 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.040584 |
| VMP1 | vacuole membrane protein 1 | 0.0405217 |
| ATP13A3 | ATPase type 13A3 | 0.0402141 |
| MSN | moesin | 0.038817 |
| SMAD3 | SMAD family member 3 | 0.0385025 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0384908 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0372635 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0371026 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0365582 |
| ECE1 | endothelin converting enzyme 1 | 0.036337 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0363175 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0357481 |
| RPL3 | ribosomal protein L3 | 0.035687 |
| RASA2 | RAS p21 protein activator 2 | 0.0341701 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0336189 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0335051 |
| TAPBP | TAP binding protein (tapasin) | 0.0327289 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0318202 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0315524 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0312936 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0312862 |
| TFG | TRK-fused gene | 0.0304519 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.03011 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0300487 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0297791 |
| CLIC4 | chloride intracellular channel 4 | 0.0293403 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0292293 |
| VEGFC | vascular endothelial growth factor C | 0.0292021 |
| DSTN | destrin (actin depolymerizing factor) | 0.0289542 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0288114 |
| COL6A1 | collagen, type VI, alpha 1 | 0.028787 |
| FLNA | filamin A, alpha | 0.0280106 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.027705 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0275545 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0275089 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0274787 |
| PTK2 | protein tyrosine kinase 2 | 0.0272105 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.027102 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0260278 |
| PKM | pyruvate kinase, muscle | 0.0260192 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0257951 |
| COPA | coatomer protein complex, subunit alpha | 0.0256711 |
| JMJD1C | jumonji domain containing 1C | 0.0256662 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0255375 |
| RNF145 | ring finger protein 145 | 0.0251345 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0250376 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0249496 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0249282 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0246576 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0246281 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0245083 |
| CCNL1 | cyclin L1 | 0.0241547 |
| TNS1 | tensin 1 | 0.0241032 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0240588 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 0.0237979 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0234084 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0231244 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0224285 |
| PCBP2 | poly(rC) binding protein 2 | 0.0224149 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0222862 |
| POTEF | POTE ankyrin domain family, member F | 0.0222029 |
| YBX1 | Y box binding protein 1 | 0.0220891 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0218582 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0218189 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0218022 |
| PLEC | plectin | 0.0217806 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0215636 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0215097 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0214956 |
| HYOU1 | hypoxia up-regulated 1 | 0.0214056 |
| PTMA | prothymosin, alpha | 0.0212954 |
| QKI | QKI, KH domain containing, RNA binding | 0.0211158 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0209992 |
| CABIN1 | calcineurin binding protein 1 | 0.0208622 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0204983 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0204244 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0203893 |
| MED13L | mediator complex subunit 13-like | 0.0203463 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.242158 |
| COL1A2 | collagen, type I, alpha 2 | -0.159259 |
| CDH13 | cadherin 13 | -0.139669 |
| VIM | vimentin | -0.138128 |
| COL1A1 | collagen, type I, alpha 1 | -0.118857 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.114191 |
| IER3 | immediate early response 3 | -0.0968011 |
| NDRG1 | N-myc downstream regulated 1 | -0.09247 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0876168 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0826492 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0673416 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0649876 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0645163 |
| CAVIN1 | caveolae associated protein 1 | -0.0620302 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0609179 |
| TMSB10 | thymosin beta 10 | -0.0606687 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0594083 |
| COL5A1 | collagen, type V, alpha 1 | -0.0590188 |
| FBN1 | fibrillin 1 | -0.0589148 |
| ASPH | aspartate beta-hydroxylase | -0.058563 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0564771 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0540095 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0537 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0485797 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0448621 |
| DPYD | dihydropyrimidine dehydrogenase | -0.044658 |
| RRBP1 | ribosome binding protein 1 | -0.0445652 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0436302 |
| STC1 | stanniocalcin 1 | -0.0425914 |
| ACTG1 | actin gamma 1 | -0.0415306 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0396924 |
| TPM4 | tropomyosin 4 | -0.039434 |
| HLA-B | major histocompatibility complex, class I, B | -0.0382759 |
| ENO1 | enolase 1, (alpha) | -0.0382377 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0377297 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0373793 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0367784 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0347992 |
| CLMP | CXADR-like membrane protein | -0.0347636 |
| GNAS | GNAS complex locus | -0.0343313 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0342201 |
| INHBA | inhibin, beta A | -0.0339992 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0326775 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0326243 |
| VCAN | versican | -0.0325869 |
| BNC2 | basonuclin 2 | -0.032271 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0322632 |
| TMSB4X | thymosin beta 4, X-linked | -0.0317195 |
| LOXL2 | lysyl oxidase-like 2 | -0.031584 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0309052 |
| S100A6 | S100 calcium binding protein A6 | -0.0304515 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0302647 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0298075 |
| CALR | calreticulin | -0.0297017 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0296552 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0295842 |
| OXR1 | oxidation resistance 1 | -0.029576 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0292156 |
| COL3A1 | collagen, type III, alpha 1 | -0.0291415 |
| KLF6 | Kruppel-like factor 6 | -0.028658 |
| OSMR | oncostatin M receptor | -0.0283202 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0282987 |
| KPNB1 | karyopherin (importin) beta 1 | -0.028157 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0272525 |
| CANX | calnexin | -0.0266815 |
| LMO4 | LIM domain only 4 | -0.026478 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0264097 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0257904 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0257354 |
| MTDH | metadherin | -0.0257242 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0256074 |
| GLIS3 | GLIS family zinc finger 3 | -0.0248126 |
| PGK1 | phosphoglycerate kinase 1 | -0.0247272 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0247238 |
| RPL26 | ribosomal protein L26 | -0.0246389 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0245557 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0244627 |
| PRRX1 | paired related homeobox 1 | -0.0244443 |
| SQSTM1 | sequestosome 1 | -0.0244241 |
| LDHA | lactate dehydrogenase A | -0.0244175 |
| SEC61G | Sec61 gamma subunit | -0.0242655 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0241757 |
| RPS24 | ribosomal protein S24 | -0.0238902 |
| S100A10 | S100 calcium binding protein A10 | -0.0234272 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0233238 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0227174 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0223348 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0221239 |
| EBF1 | early B-cell factor 1 | -0.0220356 |
| RPS3 | ribosomal protein S3 | -0.0219273 |
| TMEM165 | transmembrane protein 165 | -0.0212753 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0211611 |
| SYNJ2 | synaptojanin 2 | -0.0210361 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0208056 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0205572 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0205051 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0204332 |
| AHNAK | AHNAK nucleoprotein | -0.0202744 |
| AFF4 | AF4/FMR2 family, member 4 | -0.020273 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0202214 |
