| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetohexamide perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Acetohexamide_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.112645 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.108742 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0661981 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0653648 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0541571 |
| POTEF | POTE ankyrin domain family, member F | 0.0515762 |
| VEGFA | vascular endothelial growth factor A | 0.0471922 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0465771 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0434927 |
| MYO1E | myosin IE | 0.0434155 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0396172 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0335853 |
| SNX9 | sorting nexin 9 | 0.0329981 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0325841 |
| ASPH | aspartate beta-hydroxylase | 0.0312107 |
| EGFR | epidermal growth factor receptor | 0.0303373 |
| ABHD2 | abhydrolase domain containing 2 | 0.027779 |
| RPL3 | ribosomal protein L3 | 0.0275356 |
| TXNIP | thioredoxin interacting protein | 0.0272595 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0234031 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0231603 |
| FBXO11 | F-box protein 11 | 0.0229068 |
| TPM3 | tropomyosin 3 | 0.0225969 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0224838 |
| DIAPH1 | diaphanous-related formin 1 | 0.0222329 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0221024 |
| RCOR1 | REST corepressor 1 | 0.0218731 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0215431 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0207953 |
| SIK3 | SIK family kinase 3 | 0.0200142 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0194291 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0194089 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0189637 |
| DSPP | dentin sialophosphoprotein | 0.0186235 |
| SVIL | supervillin | 0.018487 |
| HDGF | hepatoma-derived growth factor | 0.0179234 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0176401 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0174539 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0173178 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0171937 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0171749 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0171105 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0169511 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0164845 |
| HSPA8 | heat shock 70kDa protein 8 | 0.016452 |
| MT2A | metallothionein 2A | 0.0164075 |
| AGRN | agrin | 0.0163366 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0160091 |
| CALB1 | calbindin 1, 28kDa | 0.0159808 |
| CLOCK | clock circadian regulator | 0.0159489 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0157806 |
| TUBA1B | tubulin, alpha 1b | 0.015749 |
| HYOU1 | hypoxia up-regulated 1 | 0.0156783 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0154385 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0153052 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0151335 |
| REEP3 | receptor accessory protein 3 | 0.0147838 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.0146122 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0145651 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0145427 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0144863 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0142081 |
| SETD5 | SET domain containing 5 | 0.0141498 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0141438 |
| RHOA | ras homolog family member A | 0.0140203 |
| SNX3 | sorting nexin 3 | 0.0140088 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0139769 |
| TSC22D2 | TSC22 domain family, member 2 | 0.013745 |
| YBX1 | Y box binding protein 1 | 0.0136284 |
| VCAN | versican | 0.0136152 |
| MUC17 | mucin 17, cell surface associated | 0.013604 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0134527 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0130805 |
| BRD2 | bromodomain containing 2 | 0.0130332 |
| TPM4 | tropomyosin 4 | 0.0129722 |
| ATF7 | activating transcription factor 7 | 0.012965 |
| USP53 | ubiquitin specific peptidase 53 | 0.0129456 |
| TFF1 | trefoil factor 1 | 0.0129001 |
| CLDN4 | claudin 4 | 0.0128592 |
| HSPE1 | heat shock 10kDa protein 1 | 0.012804 |
| PCBP2 | poly(rC) binding protein 2 | 0.0127349 |
| PLS1 | plastin 1 | 0.0127254 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0127178 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0127169 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | 0.0124688 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0124023 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.012251 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0121984 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0121495 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0121147 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0120527 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.012044 |
| DNM2 | dynamin 2 | 0.0120076 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0119828 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0119827 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.011824 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 0.0116415 |
| RNF217 | ring finger protein 217 | 0.0116122 |
| CENPF | centromere protein F, 350/400kDa | 0.0115791 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0115088 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.217464 |
| PTMA | prothymosin, alpha | -0.173935 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.109143 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0950777 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0919134 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0887151 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0885124 |
| TMSB10 | thymosin beta 10 | -0.0819694 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0786263 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0696133 |
| RPS24 | ribosomal protein S24 | -0.0665209 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0659816 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0641853 |
| AHNAK | AHNAK nucleoprotein | -0.0640876 |
| PIGR | polymeric immunoglobulin receptor | -0.0628887 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0628265 |
| RPL34 | ribosomal protein L34 | -0.059777 |
| RBM39 | RNA binding motif protein 39 | -0.0585576 |
| EPCAM | epithelial cell adhesion molecule | -0.0580636 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0574952 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.057429 |
| RPL26 | ribosomal protein L26 | -0.0566263 |
| OGA | O-GlcNAcase | -0.0560047 |
| GPHN | gephyrin | -0.0554826 |
| ACTN4 | actinin, alpha 4 | -0.0547722 |
| LDHA | lactate dehydrogenase A | -0.0542138 |
| EREG | epiregulin | -0.0538183 |
| RRBP1 | ribosome binding protein 1 | -0.0527826 |
| RNF43 | ring finger protein 43 | -0.0516316 |
| CADPS | Ca++-dependent secretion activator | -0.0512096 |
| NFIA | nuclear factor I/A | -0.0503598 |
| ONECUT3 | one cut homeobox 3 | -0.0477404 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0474087 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0471057 |
| RPL12 | ribosomal protein L12 | -0.0469281 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0467104 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0453939 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0452564 |
| RPS19 | ribosomal protein S19 | -0.0450567 |
| RPS3 | ribosomal protein S3 | -0.0443677 |
| PCDHB16 | protocadherin beta 16 | -0.0437886 |
| H1-0 | H1.0 linker histone | -0.0429485 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0428251 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0427968 |
| NPSR1 | neuropeptide S receptor 1 | -0.0420907 |
| SERINC5 | serine incorporator 5 | -0.0416968 |
| RPS8 | ribosomal protein S8 | -0.0416813 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0411433 |
| RPS21 | ribosomal protein S21 | -0.0408054 |
| RPLP1 | ribosomal protein, large, P1 | -0.0404694 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.040196 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0401667 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0399611 |
| PRELID2 | PRELI domain containing 2 | -0.0398338 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0397724 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0397218 |
| RPL11 | ribosomal protein L11 | -0.0390433 |
| GDF15 | growth differentiation factor 15 | -0.038709 |
| RPLP0 | ribosomal protein, large, P0 | -0.0386283 |
| GOLGA4 | golgin A4 | -0.0386278 |
| RPL9 | ribosomal protein L9 | -0.0386275 |
| TRIM2 | tripartite motif containing 2 | -0.0385124 |
| ANXA2 | annexin A2 | -0.038251 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0380604 |
| S100P | S100 calcium binding protein P | -0.0378233 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0375662 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0375432 |
| KRT18 | keratin 18, type I | -0.036441 |
| RPLP2 | ribosomal protein, large, P2 | -0.0362907 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0361149 |
| CANX | calnexin | -0.0360095 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0358856 |
| HDLBP | high density lipoprotein binding protein | -0.0355111 |
| TNS4 | tensin 4 | -0.035507 |
| RAD21 | RAD21 homolog (S. pombe) | -0.034847 |
| WDR45B | WD repeat domain 45B | -0.0347153 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0346756 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0344589 |
| NEBL | nebulette | -0.0335293 |
| EWSR1 | EWS RNA-binding protein 1 | -0.0331317 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0329529 |
| RPL5 | ribosomal protein L5 | -0.0327662 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0327039 |
| ARF1 | ADP-ribosylation factor 1 | -0.0325412 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0324957 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0322964 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0321515 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0320695 |
| TFRC | transferrin receptor | -0.0317651 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0316336 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.031557 |
| RPS6 | ribosomal protein S6 | -0.0314632 |
| RPS12 | ribosomal protein S12 | -0.0310328 |
| RPL30 | ribosomal protein L30 | -0.0307166 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0305187 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0305162 |
| PGK1 | phosphoglycerate kinase 1 | -0.0303303 |
| SHROOM3 | shroom family member 3 | -0.0302904 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0301439 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0300577 |
