| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetohexamide perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Acetohexamide_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.125803 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0928721 |
| DST | dystonin | 0.0866603 |
| RPS12 | ribosomal protein S12 | 0.0854437 |
| HLA-B | major histocompatibility complex, class I, B | 0.0754726 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0699243 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0672116 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0660518 |
| RPL12 | ribosomal protein L12 | 0.0631541 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0576951 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0576593 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0561525 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0549045 |
| RPL26 | ribosomal protein L26 | 0.0537529 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0525835 |
| PDE10A | phosphodiesterase 10A | 0.0512817 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0507152 |
| RPL37A | ribosomal protein L37a | 0.0474612 |
| CAPRIN2 | caprin family member 2 | 0.0466267 |
| RPL36 | ribosomal protein L36 | 0.0436369 |
| RPS3 | ribosomal protein S3 | 0.0434112 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0423866 |
| SFTPA2 | surfactant protein A2 | 0.042046 |
| RPL28 | ribosomal protein L28 | 0.039902 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0398482 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.039186 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0386942 |
| RPL8 | ribosomal protein L8 | 0.0384514 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0380792 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0367009 |
| RPL36A | ribosomal protein L36a | 0.0364537 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0362378 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0347708 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0334066 |
| TPM3 | tropomyosin 3 | 0.0327423 |
| JUN | jun proto-oncogene | 0.0326439 |
| RUNX1 | runt-related transcription factor 1 | 0.0323705 |
| SLK | STE20-like kinase | 0.0320683 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0317717 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.031518 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0310706 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0296497 |
| RPL37 | ribosomal protein L37 | 0.0294856 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0291536 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0289917 |
| TMSB4X | thymosin beta 4, X-linked | 0.0288051 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0287923 |
| EFNA5 | ephrin-A5 | 0.0287428 |
| RPL3 | ribosomal protein L3 | 0.0284136 |
| RPS17 | ribosomal protein S17 | 0.0273266 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0265007 |
| OPTN | optineurin | 0.0264045 |
| RPS14 | ribosomal protein S14 | 0.0261482 |
| RPS27 | ribosomal protein S27 | 0.0255198 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0253067 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0252765 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0252022 |
| H1-0 | H1.0 linker histone | 0.0249697 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0249555 |
| RPL35 | ribosomal protein L35 | 0.0245962 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0245511 |
| MCL1 | myeloid cell leukemia 1 | 0.0242487 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0242052 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0237452 |
| AHNAK | AHNAK nucleoprotein | 0.0236829 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0233827 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0229821 |
| RPS15A | ribosomal protein S15a | 0.0227783 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0223038 |
| YEATS2 | YEATS domain containing 2 | 0.0222746 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0220987 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0219024 |
| PYGB | phosphorylase, glycogen; brain | 0.0218246 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0210976 |
| VCL | vinculin | 0.0209513 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0209225 |
| PHF3 | PHD finger protein 3 | 0.0209018 |
| SEC24A | SEC24 family member A | 0.0208422 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0206937 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0202754 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0197315 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0196468 |
| RPS25 | ribosomal protein S25 | 0.0196417 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0192453 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.019156 |
| RPS7 | ribosomal protein S7 | 0.0186787 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0184228 |
| CD44 | CD44 molecule (Indian blood group) | 0.0182331 |
| FNIP1 | folliculin interacting protein 1 | 0.0182189 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0182034 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0181799 |
| RPS27A | ribosomal protein S27a | 0.0180732 |
| ECE1 | endothelin converting enzyme 1 | 0.0179536 |
| PMP22 | peripheral myelin protein 22 | 0.0178 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0176879 |
| HLA-A | major histocompatibility complex, class I, A | 0.0176472 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0176097 |
| SERINC1 | serine incorporator 1 | 0.017549 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0174874 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0174323 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.191946 |
| PTMA | prothymosin, alpha | -0.14333 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.133987 |
| FTL | ferritin, light polypeptide | -0.0960046 |
| VIM | vimentin | -0.0791736 |
| ACTG1 | actin gamma 1 | -0.0674726 |
| TMSB10 | thymosin beta 10 | -0.0671954 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0651879 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0616707 |
| MT1E | metallothionein 1E | -0.0598724 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0537435 |
| S100A6 | S100 calcium binding protein A6 | -0.0493317 |
| POTEF | POTE ankyrin domain family, member F | -0.0492756 |
| RPLP1 | ribosomal protein, large, P1 | -0.0489586 |
| ANXA1 | annexin A1 | -0.0465527 |
| RPL35A | ribosomal protein L35a | -0.0465411 |
| SEPTIN7 | septin 7 | -0.0444405 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0437547 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0432461 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0426977 |
| S100A10 | S100 calcium binding protein A10 | -0.041128 |
| MT1X | metallothionein 1X | -0.0399428 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0373882 |
| RBM25 | RNA binding motif protein 25 | -0.0368298 |
| PKM | pyruvate kinase, muscle | -0.0364312 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0364055 |
| SRGN | serglycin | -0.0362994 |
| PRDX1 | peroxiredoxin 1 | -0.0355191 |
| LDHA | lactate dehydrogenase A | -0.0353846 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0351647 |
| EMP1 | epithelial membrane protein 1 | -0.0342517 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0340212 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0339067 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0335024 |
| RTN4 | reticulon 4 | -0.0325469 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0322246 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0308493 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0305384 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0302855 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0300471 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.029562 |
| FBXO11 | F-box protein 11 | -0.0293211 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0289647 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0286027 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0273542 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0273245 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0272271 |
| FMNL2 | formin-like 2 | -0.0270341 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.026823 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0263243 |
| RPL5 | ribosomal protein L5 | -0.0261059 |
| RRM2 | ribonucleotide reductase M2 | -0.025848 |
| ERBIN | erbb2 interacting protein | -0.0257632 |
| USP34 | ubiquitin specific peptidase 34 | -0.025623 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0250942 |
| RPS4X | ribosomal protein S4, X-linked | -0.0250641 |
| FOSL1 | FOS-like antigen 1 | -0.0249864 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0249491 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0249469 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0249295 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0246378 |
| WDR45B | WD repeat domain 45B | -0.0245357 |
| RPLP0 | ribosomal protein, large, P0 | -0.0240564 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0238496 |
| YBX1 | Y box binding protein 1 | -0.0236023 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0236011 |
| FUS | FUS RNA binding protein | -0.0235393 |
| CCDC88A | coiled-coil domain containing 88A | -0.0234048 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0231854 |
| RPL23 | ribosomal protein L23 | -0.0231317 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0230488 |
| DEK | DEK proto-oncogene | -0.0227775 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0226824 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0219635 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0219156 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0217736 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0214839 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0214022 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0213669 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0212617 |
| SPIDR | scaffolding protein involved in DNA repair | -0.021188 |
| GNAS | GNAS complex locus | -0.0211492 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0211148 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0210371 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0209833 |
| RAI1 | retinoic acid induced 1 | -0.0209297 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0207293 |
| PGK1 | phosphoglycerate kinase 1 | -0.0206326 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0205854 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0205356 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0202341 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0198455 |
| ANLN | anillin, actin binding protein | -0.019795 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0197911 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0197175 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0194178 |
| SEC61G | Sec61 gamma subunit | -0.0194103 |
| CDC27 | cell division cycle 27 | -0.0193925 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0193067 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0190766 |
