| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetohexamide perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Acetohexamide_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.152202 |
| LOX | lysyl oxidase | 0.0969565 |
| TGM2 | transglutaminase 2 | 0.0965248 |
| CD44 | CD44 molecule (Indian blood group) | 0.0927163 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.079149 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0763625 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0601354 |
| NAV2 | neuron navigator 2 | 0.0556806 |
| VMP1 | vacuole membrane protein 1 | 0.0518558 |
| STK38L | serine/threonine kinase 38 like | 0.0489185 |
| KSR1 | kinase suppressor of ras 1 | 0.0467812 |
| NTN4 | netrin 4 | 0.0466857 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0429201 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0427531 |
| EFNA5 | ephrin-A5 | 0.042487 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0421137 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.040792 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0406458 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0404681 |
| IL1R1 | interleukin 1 receptor, type I | 0.0403809 |
| PCBP2 | poly(rC) binding protein 2 | 0.038377 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0372068 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0369747 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0356047 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0346531 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0344542 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0330369 |
| AADAC | arylacetamide deacetylase | 0.0327371 |
| HMGA2 | high mobility group AT-hook 2 | 0.0327309 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0323184 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.031451 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0311794 |
| ECE1 | endothelin converting enzyme 1 | 0.0309468 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0304897 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0302225 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0300498 |
| SIK3 | SIK family kinase 3 | 0.0283507 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0282064 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0279992 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0278349 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0276955 |
| SEPTIN9 | septin 9 | 0.0273801 |
| TNNC1 | troponin C type 1 (slow) | 0.0272992 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0271732 |
| MYO10 | myosin X | 0.0268346 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0267541 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0250579 |
| COPA | coatomer protein complex, subunit alpha | 0.0249195 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0245892 |
| RPL3 | ribosomal protein L3 | 0.0242639 |
| MEIS1 | Meis homeobox 1 | 0.0237067 |
| TUT7 | terminal uridylyl transferase 7 | 0.0236906 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0236252 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0232652 |
| MCL1 | myeloid cell leukemia 1 | 0.0227842 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0224114 |
| HDAC9 | histone deacetylase 9 | 0.0221951 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0219478 |
| SMAD3 | SMAD family member 3 | 0.0219148 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0218716 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0218653 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.021431 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0212922 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0210025 |
| CAPRIN2 | caprin family member 2 | 0.0202813 |
| RNF144A | ring finger protein 144A | 0.0199436 |
| VEGFA | vascular endothelial growth factor A | 0.0199178 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0192896 |
| NOTCH2 | notch 2 | 0.0191821 |
| FAM219A | family with sequence similarity 219, member A | 0.0191629 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0188911 |
| ARHGAP17 | Rho GTPase activating protein 17 | 0.0188677 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0185982 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0185831 |
| LOXL2 | lysyl oxidase-like 2 | 0.018563 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0183272 |
| ATF7 | activating transcription factor 7 | 0.0180654 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0179355 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0172883 |
| FHL2 | four and a half LIM domains 2 | 0.017205 |
| USP47 | ubiquitin specific peptidase 47 | 0.0165844 |
| VCL | vinculin | 0.0165522 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0165327 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.016208 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0160636 |
| ANO6 | anoctamin 6 | 0.0159209 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0158608 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa | 0.0157994 |
| EGFR | epidermal growth factor receptor | 0.0157091 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.014941 |
| RHCG | Rh family, C glycoprotein | 0.0149339 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0148629 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.014774 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0144609 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0141393 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0139998 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0139731 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0138768 |
| TLN1 | talin 1 | 0.0138536 |
| CUL3 | cullin 3 | 0.0138269 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.204968 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.181685 |
| VIM | vimentin | -0.155678 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.127193 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.106627 |
| PTMA | prothymosin, alpha | -0.0956964 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0931867 |
| FTL | ferritin, light polypeptide | -0.0774503 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0744744 |
| RPLP1 | ribosomal protein, large, P1 | -0.074444 |
| STC1 | stanniocalcin 1 | -0.0714673 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0678042 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0669589 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0660637 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0645118 |
| S100A6 | S100 calcium binding protein A6 | -0.0588646 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0574712 |
| B2M | beta-2-microglobulin | -0.0543356 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0541587 |
| GPC6 | glypican 6 | -0.0537938 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0523003 |
| IER3 | immediate early response 3 | -0.051704 |
| RPS21 | ribosomal protein S21 | -0.0513726 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0511098 |
| RPS19 | ribosomal protein S19 | -0.0510834 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0510364 |
| RPL35A | ribosomal protein L35a | -0.0499564 |
| RPS24 | ribosomal protein S24 | -0.0494586 |
| TMSB4X | thymosin beta 4, X-linked | -0.0478823 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0465756 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0464593 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.045127 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0447073 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0440418 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0436796 |
| NRG1 | neuregulin 1 | -0.0433377 |
| RPS6 | ribosomal protein S6 | -0.0424829 |
| CDH13 | cadherin 13 | -0.0424786 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.042315 |
| RPL36 | ribosomal protein L36 | -0.0413399 |
| ENO1 | enolase 1, (alpha) | -0.0412804 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0411863 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0411121 |
| CANX | calnexin | -0.0410838 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0407153 |
| RBM39 | RNA binding motif protein 39 | -0.0406832 |
| RPS8 | ribosomal protein S8 | -0.0403972 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0388807 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0381629 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0379813 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0379426 |
| FAM13A | family with sequence similarity 13, member A | -0.037852 |
| PRELID2 | PRELI domain containing 2 | -0.0377875 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0375569 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0373928 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0365074 |
| GNAS | GNAS complex locus | -0.0361968 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0358339 |
| RPL34 | ribosomal protein L34 | -0.0357971 |
| RPL37A | ribosomal protein L37a | -0.0355406 |
| RPL31 | ribosomal protein L31 | -0.0352771 |
| SQSTM1 | sequestosome 1 | -0.035223 |
| RPL11 | ribosomal protein L11 | -0.0347441 |
| HLA-B | major histocompatibility complex, class I, B | -0.0344582 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0343943 |
| MECOM | MDS1 and EVI1 complex locus | -0.0337675 |
| RPL23 | ribosomal protein L23 | -0.0331449 |
| RPLP0 | ribosomal protein, large, P0 | -0.0330961 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.032866 |
| SYT1 | synaptotagmin I | -0.0328115 |
| TXNRD1 | thioredoxin reductase 1 | -0.0319676 |
| RPL38 | ribosomal protein L38 | -0.0319437 |
| PKM | pyruvate kinase, muscle | -0.031723 |
| RPL32 | ribosomal protein L32 | -0.0316888 |
| FMNL2 | formin-like 2 | -0.031464 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0314013 |
| RPLP2 | ribosomal protein, large, P2 | -0.0313918 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0312295 |
| LDHA | lactate dehydrogenase A | -0.0311285 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0310263 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0308181 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0307974 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0307575 |
| S100A10 | S100 calcium binding protein A10 | -0.0306298 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0306223 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0306052 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0304384 |
| ZNF292 | zinc finger protein 292 | -0.0303996 |
| RPS29 | ribosomal protein S29 | -0.029966 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0299086 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0297441 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0295941 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0293748 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0292365 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.029228 |
| PARD3 | par-3 family cell polarity regulator | -0.0288277 |
| RAI1 | retinoic acid induced 1 | -0.0286682 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0283204 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0279409 |
| TMEM165 | transmembrane protein 165 | -0.027804 |
