| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetohexamide perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Acetohexamide_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.264044 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0923299 |
| TXNRD1 | thioredoxin reductase 1 | 0.0765865 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0754741 |
| AHNAK | AHNAK nucleoprotein | 0.0592938 |
| H1-0 | H1.0 linker histone | 0.0449409 |
| GRAMD1B | GRAM domain containing 1B | 0.040795 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0393271 |
| CAVIN1 | caveolae associated protein 1 | 0.0335011 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.032086 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0320787 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0319371 |
| MAP4 | microtubule-associated protein 4 | 0.0314055 |
| TPM3 | tropomyosin 3 | 0.0287634 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0284052 |
| RPL3 | ribosomal protein L3 | 0.0276394 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0269005 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0267962 |
| GOLGB1 | golgin B1 | 0.0252176 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0248675 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0245308 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0242247 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0241321 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.023337 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0228068 |
| ADAR | adenosine deaminase, RNA-specific | 0.0225267 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0222785 |
| CANX | calnexin | 0.022098 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0219486 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0219078 |
| RPL4 | ribosomal protein L4 | 0.0217397 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0214053 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0210005 |
| DST | dystonin | 0.02083 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0206968 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0199971 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.019849 |
| MMP12 | matrix metallopeptidase 12 | 0.0196246 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0193502 |
| AK4 | adenylate kinase 4 | 0.0193229 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0192645 |
| PLEC | plectin | 0.0190426 |
| CLTC | clathrin, heavy chain (Hc) | 0.0189659 |
| DSPP | dentin sialophosphoprotein | 0.0189549 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0187113 |
| KLF6 | Kruppel-like factor 6 | 0.0186757 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0185866 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0184625 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0183338 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0182658 |
| TLN1 | talin 1 | 0.0180637 |
| RPS7 | ribosomal protein S7 | 0.0179434 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0178923 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0178371 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0178055 |
| SFTPA2 | surfactant protein A2 | 0.0176517 |
| SMAD3 | SMAD family member 3 | 0.0175909 |
| PHF3 | PHD finger protein 3 | 0.0175893 |
| CTTN | cortactin | 0.0174142 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0173341 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0172397 |
| SERINC1 | serine incorporator 1 | 0.0171956 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0171892 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0169477 |
| ZNF217 | zinc finger protein 217 | 0.0166984 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0163499 |
| APP | amyloid beta (A4) precursor protein | 0.0163453 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0162095 |
| RAB10 | RAB10, member RAS oncogene family | 0.0161847 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0161331 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0159709 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0158965 |
| OGA | O-GlcNAcase | 0.0158173 |
| ANO6 | anoctamin 6 | 0.0157597 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0156838 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0156668 |
| RPL6 | ribosomal protein L6 | 0.0154824 |
| HDLBP | high density lipoprotein binding protein | 0.015474 |
| MKI67 | marker of proliferation Ki-67 | 0.0153526 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0153281 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | 0.0152932 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0150053 |
| JUN | jun proto-oncogene | 0.0147662 |
| JAK1 | Janus kinase 1 | 0.0146253 |
| RPL14 | ribosomal protein L14 | 0.0145979 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0144974 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0144163 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0142779 |
| KCTD20 | potassium channel tetramerization domain containing 20 | 0.0141139 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0140402 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0139906 |
| ANXA1 | annexin A1 | 0.0138568 |
| ICAM1 | intercellular adhesion molecule 1 | 0.013782 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0137505 |
| EREG | epiregulin | 0.0136318 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0135224 |
| RBM39 | RNA binding motif protein 39 | 0.0134263 |
| ATM | ATM serine/threonine kinase | 0.0133085 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0132602 |
| DENND5B | DENN/MADD domain containing 5B | 0.0132221 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.244736 |
| TMSB10 | thymosin beta 10 | -0.150121 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.100713 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0913295 |
| POTEF | POTE ankyrin domain family, member F | -0.0701841 |
| EGR1 | early growth response 1 | -0.0645915 |
| RPLP1 | ribosomal protein, large, P1 | -0.0638296 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0630808 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0608026 |
| PTMA | prothymosin, alpha | -0.0592347 |
| TPI1 | triosephosphate isomerase 1 | -0.0592112 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0553418 |
| RPL35A | ribosomal protein L35a | -0.0549525 |
| VIM | vimentin | -0.0519086 |
| PCBP2 | poly(rC) binding protein 2 | -0.0509152 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0478358 |
| RPS8 | ribosomal protein S8 | -0.0471469 |
| RPL37 | ribosomal protein L37 | -0.0451359 |
| RPS19 | ribosomal protein S19 | -0.0443075 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0431248 |
| RPL37A | ribosomal protein L37a | -0.0428221 |
| RPS21 | ribosomal protein S21 | -0.0416046 |
| RPL23 | ribosomal protein L23 | -0.0408676 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0399523 |
| ACTG1 | actin gamma 1 | -0.0396195 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0388936 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0376966 |
| PDE10A | phosphodiesterase 10A | -0.0374889 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0373379 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0366338 |
| RPLP0 | ribosomal protein, large, P0 | -0.0361317 |
| FBXO11 | F-box protein 11 | -0.0353974 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0349542 |
| RPS15 | ribosomal protein S15 | -0.0347937 |
| RPS10 | ribosomal protein S10 | -0.0344172 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0344026 |
| SEPTIN7 | septin 7 | -0.0341426 |
| LDHB | lactate dehydrogenase B | -0.0337261 |
| PTK2 | protein tyrosine kinase 2 | -0.0334332 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0333191 |
| HLA-B | major histocompatibility complex, class I, B | -0.0330888 |
| RPL31 | ribosomal protein L31 | -0.0328237 |
| RPS4X | ribosomal protein S4, X-linked | -0.0328236 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0327872 |
| RPS27 | ribosomal protein S27 | -0.0319823 |
| TUBA1B | tubulin, alpha 1b | -0.0314111 |
| PFN1 | profilin 1 | -0.0313749 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0311894 |
| RPL5 | ribosomal protein L5 | -0.0308759 |
| RPS29 | ribosomal protein S29 | -0.0307598 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0306355 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0300494 |
| RPS6 | ribosomal protein S6 | -0.0294581 |
| MCL1 | myeloid cell leukemia 1 | -0.0293293 |
| RPL9 | ribosomal protein L9 | -0.0292872 |
| RSF1 | remodeling and spacing factor 1 | -0.029018 |
| RPS17 | ribosomal protein S17 | -0.0286639 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0284778 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0284482 |
| PKM | pyruvate kinase, muscle | -0.0283867 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0282935 |
| MORF4L2 | mortality factor 4 like 2 | -0.0282388 |
| RPL12 | ribosomal protein L12 | -0.0275857 |
| RAD51B | RAD51 paralog B | -0.026617 |
| MT2A | metallothionein 2A | -0.0259466 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0253191 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0252238 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0248736 |
| RPL7A | ribosomal protein L7a | -0.0248222 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0244478 |
| CBX3 | chromobox homolog 3 | -0.0244073 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0242728 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0242437 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0242089 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0239998 |
| PTMS | parathymosin | -0.0239689 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0239235 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0236809 |
| RPL27 | ribosomal protein L27 | -0.0236301 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0236158 |
| HOMER1 | homer scaffolding protein 1 | -0.0234882 |
| RBM25 | RNA binding motif protein 25 | -0.0232423 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0231687 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0231521 |
| YBX1 | Y box binding protein 1 | -0.0230529 |
| WWOX | WW domain containing oxidoreductase | -0.0229086 |
| RPL34 | ribosomal protein L34 | -0.0225826 |
| FTL | ferritin, light polypeptide | -0.0225798 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0225123 |
| ATXN1 | ataxin 1 | -0.0224798 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0224571 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.0224381 |
| SEC61G | Sec61 gamma subunit | -0.0223993 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0223881 |
| WDR43 | WD repeat domain 43 | -0.0221143 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0220999 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0220477 |
| S100A6 | S100 calcium binding protein A6 | -0.0220199 |
| USP36 | ubiquitin specific peptidase 36 | -0.021947 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0218947 |
