| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetohexamide perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Acetohexamide_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.135588 |
| FN1 | fibronectin 1 | 0.132935 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0961168 |
| POTEF | POTE ankyrin domain family, member F | 0.089892 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0872741 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0847022 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0809468 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0669064 |
| TPM3 | tropomyosin 3 | 0.0647665 |
| MSN | moesin | 0.0615363 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0590397 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0583238 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0574849 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0568785 |
| RPL8 | ribosomal protein L8 | 0.0561543 |
| FAM13A | family with sequence similarity 13, member A | 0.0548041 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.053774 |
| VEGFA | vascular endothelial growth factor A | 0.0537199 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0488968 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0470927 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.046506 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0449829 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0431728 |
| RPL3 | ribosomal protein L3 | 0.0425445 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0419568 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0411 |
| PCBP2 | poly(rC) binding protein 2 | 0.039051 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0388231 |
| RNF145 | ring finger protein 145 | 0.0375976 |
| FLNB | filamin B, beta | 0.0370168 |
| FTL | ferritin, light polypeptide | 0.0369235 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0368051 |
| RCOR1 | REST corepressor 1 | 0.0363065 |
| TMF1 | TATA element modulatory factor 1 | 0.0350893 |
| PLEC | plectin | 0.0348349 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0338326 |
| CCNL1 | cyclin L1 | 0.0328814 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0328232 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0324717 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0310864 |
| RPS3 | ribosomal protein S3 | 0.0310168 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0308999 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0297135 |
| SETD5 | SET domain containing 5 | 0.0294814 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0292081 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0288239 |
| GOLGA4 | golgin A4 | 0.0285644 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.028265 |
| EFNA5 | ephrin-A5 | 0.0274181 |
| SFTPA2 | surfactant protein A2 | 0.0272761 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0268296 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0267751 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0267454 |
| CTBP2 | C-terminal binding protein 2 | 0.0267312 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0267041 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0265471 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0264771 |
| CD109 | CD109 molecule | 0.0258562 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0258178 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0256971 |
| DSPP | dentin sialophosphoprotein | 0.0256258 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0256038 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0255414 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0254444 |
| ASPH | aspartate beta-hydroxylase | 0.0250793 |
| RPS12 | ribosomal protein S12 | 0.024901 |
| MCL1 | myeloid cell leukemia 1 | 0.0246456 |
| NAV2 | neuron navigator 2 | 0.0245842 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0245027 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0242064 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.023906 |
| RPS6 | ribosomal protein S6 | 0.0236581 |
| TMEM165 | transmembrane protein 165 | 0.0235048 |
| SPAG9 | sperm associated antigen 9 | 0.022938 |
| COPA | coatomer protein complex, subunit alpha | 0.0228138 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0228027 |
| YTHDC1 | YTH domain containing 1 | 0.0226108 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0220568 |
| MAP1B | microtubule-associated protein 1B | 0.0220555 |
| HDGF | hepatoma-derived growth factor | 0.0219622 |
| RBM25 | RNA binding motif protein 25 | 0.02187 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0217759 |
| EZR | ezrin | 0.0216477 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0216473 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0215258 |
| BRD2 | bromodomain containing 2 | 0.0214945 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0214505 |
| RBM39 | RNA binding motif protein 39 | 0.0212884 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0212225 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.021142 |
| WASF2 | WAS protein family, member 2 | 0.0209058 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0207711 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0207652 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0207394 |
| YAP1 | Yes-associated protein 1 | 0.0207055 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0207053 |
| FLNA | filamin A, alpha | 0.0203817 |
| PAPOLA | poly(A) polymerase alpha | 0.0201843 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.020183 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.020173 |
| Symbol | Name | Standardized Value |
|---|---|---|
| S100A6 | S100 calcium binding protein A6 | -0.0927772 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0927697 |
| RPL35A | ribosomal protein L35a | -0.071674 |
| TMSB10 | thymosin beta 10 | -0.0652235 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0631392 |
| LMO7 | LIM domain 7 | -0.0579882 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0555163 |
| ACTG1 | actin gamma 1 | -0.0542092 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0518566 |
| RPLP1 | ribosomal protein, large, P1 | -0.0510363 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0490739 |
| PTMA | prothymosin, alpha | -0.0480969 |
| CCND1 | cyclin D1 | -0.0446342 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0417443 |
| S100A10 | S100 calcium binding protein A10 | -0.0404276 |
| RPL34 | ribosomal protein L34 | -0.0396019 |
| SQSTM1 | sequestosome 1 | -0.0395863 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0391557 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0390123 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0357894 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0345875 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0340135 |
| RPL30 | ribosomal protein L30 | -0.0311969 |
| KRT7 | keratin 7, type II | -0.0298245 |
| TMSB4X | thymosin beta 4, X-linked | -0.0296082 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0293579 |
| RPS24 | ribosomal protein S24 | -0.02918 |
| LDHA | lactate dehydrogenase A | -0.0279495 |
| RPLP0 | ribosomal protein, large, P0 | -0.0276018 |
| FBXO32 | F-box protein 32 | -0.026817 |
| CSTB | cystatin B (stefin B) | -0.0264941 |
| PLAU | plasminogen activator, urokinase | -0.0263183 |
| SP100 | SP100 nuclear antigen | -0.0259425 |
| EPCAM | epithelial cell adhesion molecule | -0.0254887 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.024888 |
| CD2AP | CD2-associated protein | -0.02433 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.023601 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0234316 |
| RPL27A | ribosomal protein L27a | -0.0232518 |
| ARF1 | ADP-ribosylation factor 1 | -0.0226861 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0225949 |
| ANXA2 | annexin A2 | -0.0225575 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0225174 |
| MX2 | MX dynamin-like GTPase 2 | -0.0224886 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0217968 |
| H3-3B | H3.3 histone B | -0.0217318 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0206598 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0206409 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0203293 |
| HLA-B | major histocompatibility complex, class I, B | -0.0202682 |
| GNAS | GNAS complex locus | -0.019881 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0196281 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0190189 |
| RAD21 | RAD21 homolog (S. pombe) | -0.018893 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0188454 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0187485 |
| VCL | vinculin | -0.0183578 |
| PLSCR1 | phospholipid scramblase 1 | -0.0182991 |
| RPL23 | ribosomal protein L23 | -0.0181614 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.01765 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0175644 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0175632 |
| NPC2 | Niemann-Pick disease, type C2 | -0.0172273 |
| RPL37 | ribosomal protein L37 | -0.0171452 |
| TMEM263 | transmembrane protein 263 | -0.0170669 |
| RIGI | RNA sensor RIG-I | -0.0170401 |
| HMGB2 | high mobility group box 2 | -0.017039 |
| FBXO34 | F-box protein 34 | -0.0168616 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0168598 |
| RPL26 | ribosomal protein L26 | -0.0166881 |
| ETV6 | ets variant 6 | -0.0165587 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0165062 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0164095 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0163455 |
| KRT18 | keratin 18, type I | -0.0161816 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0158006 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0156492 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.01564 |
| CD63 | CD63 molecule | -0.015491 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.015164 |
| S100A4 | S100 calcium binding protein A4 | -0.0149798 |
| HMGB1 | high mobility group box 1 | -0.0149357 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0149226 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0147263 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides | -0.0146438 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0144833 |
| HLA-E | major histocompatibility complex, class I, E | -0.0143503 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0142387 |
| MUC20 | mucin 20, cell surface associated | -0.0141908 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0141757 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0141683 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0140393 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0137771 |
| TMEM123 | transmembrane protein 123 | -0.0136355 |
| RPL38 | ribosomal protein L38 | -0.0135407 |
| ZNF217 | zinc finger protein 217 | -0.0134638 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.013457 |
| RPS16 | ribosomal protein S16 | -0.0134494 |
| GRAMD2B | GRAM domain containing 2B | -0.0134485 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0133037 |
