| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetohexamide perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Acetohexamide_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0972524 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0861456 |
| EGFR | epidermal growth factor receptor | 0.0781263 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.077136 |
| LMO7 | LIM domain 7 | 0.0730121 |
| DST | dystonin | 0.0724655 |
| COL5A2 | collagen, type V, alpha 2 | 0.0719632 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0647145 |
| JMJD1C | jumonji domain containing 1C | 0.0616325 |
| PRELID2 | PRELI domain containing 2 | 0.0599509 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0572663 |
| BMERB1 | bMERB domain containing 1 | 0.0547787 |
| RIGI | RNA sensor RIG-I | 0.0542457 |
| YAP1 | Yes-associated protein 1 | 0.0540902 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0510096 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0509 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0506891 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0465167 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0456212 |
| RUNX1 | runt-related transcription factor 1 | 0.0454054 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0446075 |
| MMP12 | matrix metallopeptidase 12 | 0.0429082 |
| DENND1A | DENN/MADD domain containing 1A | 0.0417659 |
| USP34 | ubiquitin specific peptidase 34 | 0.0415619 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0412996 |
| FLNB | filamin B, beta | 0.0395723 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0394879 |
| ANO6 | anoctamin 6 | 0.0391316 |
| EHBP1 | EH domain binding protein 1 | 0.0383407 |
| DIAPH2 | diaphanous-related formin 2 | 0.0370911 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0365579 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0359239 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.03566 |
| FN1 | fibronectin 1 | 0.0355864 |
| ASPH | aspartate beta-hydroxylase | 0.0355278 |
| NABP1 | nucleic acid binding protein 1 | 0.035391 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0353679 |
| FRMD5 | FERM domain containing 5 | 0.0353506 |
| ZNF292 | zinc finger protein 292 | 0.0352394 |
| FOXP1 | forkhead box P1 | 0.0352093 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0348056 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0346645 |
| VCL | vinculin | 0.0342985 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0340505 |
| CDH13 | cadherin 13 | 0.0339524 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0333853 |
| HDAC9 | histone deacetylase 9 | 0.0332428 |
| CNKSR3 | CNKSR family member 3 | 0.0327728 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0326303 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0321136 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.031421 |
| AREG | amphiregulin | 0.0309948 |
| SBF2 | SET binding factor 2 | 0.0309924 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0307446 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0304939 |
| WWOX | WW domain containing oxidoreductase | 0.0303159 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0294498 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.029342 |
| FMNL2 | formin-like 2 | 0.0290189 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0289554 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0286882 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0280817 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0280176 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0279743 |
| PGK1 | phosphoglycerate kinase 1 | 0.0274755 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0272035 |
| NLGN1 | neuroligin 1 | 0.0271097 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0269974 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0264541 |
| VEGFA | vascular endothelial growth factor A | 0.0257562 |
| PHF21A | PHD finger protein 21A | 0.0256529 |
| MYO1E | myosin IE | 0.0256429 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0255836 |
| FAM107B | family with sequence similarity 107, member B | 0.0254813 |
| RPL12 | ribosomal protein L12 | 0.0252977 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0251152 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0250428 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0250008 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0248223 |
| IGF2 | insulin-like growth factor 2 | 0.024729 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0246266 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0243078 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0240739 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0240575 |
| CMIP | c-Maf inducing protein | 0.0240528 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0239784 |
| STK24 | serine/threonine kinase 24 | 0.0239419 |
| SQSTM1 | sequestosome 1 | 0.0239389 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0238924 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0228358 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0226387 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0216531 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0212915 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0211296 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0210642 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0208685 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0208077 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0207788 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0207763 |
| ANXA2 | annexin A2 | 0.0205336 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.121142 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.104629 |
| VIM | vimentin | -0.0968397 |
| FTL | ferritin, light polypeptide | -0.0773538 |
| TMSB10 | thymosin beta 10 | -0.0742943 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0709478 |
| CANX | calnexin | -0.0703338 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0696856 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0663562 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0636296 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0624867 |
| FAM13A | family with sequence similarity 13, member A | -0.0602711 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0593102 |
| B2M | beta-2-microglobulin | -0.0591572 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0582466 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0570327 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0528232 |
| RPL35A | ribosomal protein L35a | -0.049184 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0489272 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0488461 |
| MMP1 | matrix metallopeptidase 1 | -0.0487027 |
| CCNI | cyclin I | -0.0466784 |
| HELZ | helicase with zinc finger | -0.0463192 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0451015 |
| PTMA | prothymosin, alpha | -0.0427219 |
| COL1A1 | collagen, type I, alpha 1 | -0.0414641 |
| ATP13A3 | ATPase type 13A3 | -0.0411302 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0410792 |
| MED13 | mediator complex subunit 13 | -0.0408248 |
| RPL19 | ribosomal protein L19 | -0.0395609 |
| BPTF | bromodomain PHD finger transcription factor | -0.0394041 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0381159 |
| RTN4 | reticulon 4 | -0.0379127 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0376752 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0374782 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.036464 |
| RPL23 | ribosomal protein L23 | -0.0360545 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0360121 |
| SETD5 | SET domain containing 5 | -0.0354894 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0352581 |
| LAMB3 | laminin, beta 3 | -0.0346158 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0333554 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.032914 |
| PTK2 | protein tyrosine kinase 2 | -0.0328731 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0325477 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0325387 |
| ACTG1 | actin gamma 1 | -0.0324564 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.032404 |
| ZNF148 | zinc finger protein 148 | -0.0320142 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0314396 |
| ANKRD12 | ankyrin repeat domain 12 | -0.031394 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0306658 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0296502 |
| PDE8A | phosphodiesterase 8A | -0.0294197 |
| VGF | VGF nerve growth factor inducible | -0.0291371 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0291313 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0288598 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0286751 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0283464 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0282788 |
| MATR3 | matrin 3 | -0.0275118 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0271096 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0267317 |
| S100A10 | S100 calcium binding protein A10 | -0.0266334 |
| INHBA | inhibin, beta A | -0.026399 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0263912 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0263 |
| HMGA2 | high mobility group AT-hook 2 | -0.0262468 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0259437 |
| PDE10A | phosphodiesterase 10A | -0.0258853 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0249457 |
| H3-3B | H3.3 histone B | -0.0239221 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0234883 |
| SFTPA2 | surfactant protein A2 | -0.023271 |
| GOLGA4 | golgin A4 | -0.0232217 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0219075 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0218082 |
| STC1 | stanniocalcin 1 | -0.0215247 |
| HLA-B | major histocompatibility complex, class I, B | -0.0211609 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0202516 |
| SEPTIN2 | septin 2 | -0.0198746 |
| RBM39 | RNA binding motif protein 39 | -0.0196247 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0184589 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0179427 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0177618 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0175107 |
| RPS16 | ribosomal protein S16 | -0.0172712 |
| OGA | O-GlcNAcase | -0.0170676 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0170484 |
| RPL34 | ribosomal protein L34 | -0.0158248 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.015028 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0148908 |
| HDLBP | high density lipoprotein binding protein | -0.0146113 |
| RPS24 | ribosomal protein S24 | -0.0136535 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0131458 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0129505 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0127251 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0122033 |
| TPR | translocated promoter region, nuclear basket protein | -0.0115338 |
| TOP1 | topoisomerase (DNA) I | -0.0115336 |
