| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetohexamide perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Acetohexamide_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TSC22D2 | TSC22 domain family, member 2 | 0.111076 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0700032 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0477284 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0427044 |
| CDC73 | cell division cycle 73 | 0.0402375 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0402249 |
| PRTG | protogenin | 0.0399 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0384176 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0381654 |
| FBXO11 | F-box protein 11 | 0.0375546 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0351785 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0349217 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0340575 |
| RBM33 | RNA binding motif protein 33 | 0.033196 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0321521 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0320835 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0320021 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0304632 |
| POTEF | POTE ankyrin domain family, member F | 0.030088 |
| PCBP2 | poly(rC) binding protein 2 | 0.0297528 |
| SETD5 | SET domain containing 5 | 0.0294209 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.028869 |
| NTM | neurotrimin | 0.0288203 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0287692 |
| PFN1 | profilin 1 | 0.0283786 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0279165 |
| WDR43 | WD repeat domain 43 | 0.0278227 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0274296 |
| NCKAP1 | NCK-associated protein 1 | 0.0270831 |
| SLK | STE20-like kinase | 0.0267171 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0266304 |
| RNF145 | ring finger protein 145 | 0.026494 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0264548 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0263531 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | 0.0262289 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.0259033 |
| RPL3 | ribosomal protein L3 | 0.0255433 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0254846 |
| CCNL1 | cyclin L1 | 0.0254583 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.025417 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.0254137 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0254117 |
| PDS5B | PDS5 cohesin associated factor B | 0.0253324 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0243139 |
| NUP58 | nucleoporin 58 | 0.0242601 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0240909 |
| DST | dystonin | 0.0240303 |
| KIF1B | kinesin family member 1B | 0.0239616 |
| ANK2 | ankyrin 2, neuronal | 0.023827 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0236702 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0234029 |
| ANKRD33B | ankyrin repeat domain 33B | 0.022892 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0228393 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0228047 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0227665 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0225384 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0224872 |
| RANBP9 | RAN binding protein 9 | 0.0222869 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 0.0220971 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0220203 |
| COLEC11 | collectin sub-family member 11 | 0.0218849 |
| TFG | TRK-fused gene | 0.0218238 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0217723 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0217512 |
| GPC4 | glypican 4 | 0.0216898 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.0214878 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0214815 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.021285 |
| ECT2 | epithelial cell transforming 2 | 0.02118 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0211521 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0209514 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0208118 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0205617 |
| YAP1 | Yes-associated protein 1 | 0.0204795 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0203838 |
| BRD4 | bromodomain containing 4 | 0.0200337 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0200268 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0199197 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0198761 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0197904 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0197458 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0196469 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0195082 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0194591 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.0194349 |
| RASAL2 | RAS protein activator like 2 | 0.0194074 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0193365 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0193181 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0192784 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0192365 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0190607 |
| CCN2 | cellular communication network factor 2 | 0.0190207 |
| FAM168A | family with sequence similarity 168, member A | 0.0189996 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0188309 |
| CRY1 | cryptochrome circadian clock 1 | 0.0188297 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0187391 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0187383 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0186271 |
| PLPP1 | phospholipid phosphatase 1 | 0.0186116 |
| HMGA2 | high mobility group AT-hook 2 | 0.0185992 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.187021 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.122221 |
| COL3A1 | collagen, type III, alpha 1 | -0.102423 |
| TMSB10 | thymosin beta 10 | -0.0904124 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0894792 |
| ACTG1 | actin gamma 1 | -0.0818629 |
| PCDH9 | protocadherin 9 | -0.0760864 |
| RPS16 | ribosomal protein S16 | -0.0708697 |
| GPC3 | glypican 3 | -0.0651838 |
| THBS1 | thrombospondin 1 | -0.0626472 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0598572 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0583713 |
| RPLP1 | ribosomal protein, large, P1 | -0.0577781 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0569787 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0569342 |
| TMSB4X | thymosin beta 4, X-linked | -0.0557722 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0557266 |
| CADM2 | cell adhesion molecule 2 | -0.0552707 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0533393 |
| RPS8 | ribosomal protein S8 | -0.0529438 |
| COL1A2 | collagen, type I, alpha 2 | -0.0522014 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0520304 |
| PTMA | prothymosin, alpha | -0.0512224 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0502552 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0492921 |
| AHNAK | AHNAK nucleoprotein | -0.0491153 |
| ENO1 | enolase 1, (alpha) | -0.0489848 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0486473 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0478801 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0477484 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0473943 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0470343 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0469484 |
| GNAS | GNAS complex locus | -0.0436819 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0433438 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.041293 |
| RPL19 | ribosomal protein L19 | -0.0407443 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0402233 |
| RPL23 | ribosomal protein L23 | -0.0385773 |
| RPS27A | ribosomal protein S27a | -0.0381092 |
| HMCN1 | hemicentin 1 | -0.0378287 |
| RPL35A | ribosomal protein L35a | -0.0375504 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0368648 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0367182 |
| RPL34 | ribosomal protein L34 | -0.036214 |
| NPAS3 | neuronal PAS domain protein 3 | -0.035542 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0349373 |
| RPS13 | ribosomal protein S13 | -0.0348069 |
| EMP1 | epithelial membrane protein 1 | -0.0347573 |
| ACTN4 | actinin, alpha 4 | -0.0346374 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0345737 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0338708 |
| RPS19 | ribosomal protein S19 | -0.0335448 |
| PRELID2 | PRELI domain containing 2 | -0.0335184 |
| PEG10 | paternally expressed 10 | -0.0333981 |
| RPS21 | ribosomal protein S21 | -0.0330803 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0322646 |
| HMGB1 | high mobility group box 1 | -0.0319134 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0315785 |
| RPL37 | ribosomal protein L37 | -0.0315383 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0312718 |
| RPL12 | ribosomal protein L12 | -0.0312232 |
| LIN28B | lin-28 homolog B (C. elegans) | -0.0310487 |
| MKI67 | marker of proliferation Ki-67 | -0.0305309 |
| RPL7 | ribosomal protein L7 | -0.0302678 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0291382 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0291237 |
| CAVIN1 | caveolae associated protein 1 | -0.0289978 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0286181 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0285235 |
| EAPP | E2F-associated phosphoprotein | -0.0284688 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0282588 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0281236 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0280064 |
| SEPTIN7 | septin 7 | -0.0275126 |
| DEK | DEK proto-oncogene | -0.0273496 |
| RPS6 | ribosomal protein S6 | -0.0268636 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0267509 |
| RPL26 | ribosomal protein L26 | -0.0267371 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0266145 |
| S100A10 | S100 calcium binding protein A10 | -0.0264826 |
| TPR | translocated promoter region, nuclear basket protein | -0.0263449 |
| RPS24 | ribosomal protein S24 | -0.0262674 |
| WDR70 | WD repeat domain 70 | -0.0260542 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0257936 |
| SRP72 | signal recognition particle 72kDa | -0.0253311 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.025318 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0253062 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0252706 |
| RPLP0 | ribosomal protein, large, P0 | -0.0251999 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0250678 |
| RPLP2 | ribosomal protein, large, P2 | -0.0246585 |
| PRDX1 | peroxiredoxin 1 | -0.0246172 |
| POU3F2 | POU class 3 homeobox 2 | -0.024471 |
| CBX3 | chromobox homolog 3 | -0.0243379 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0243214 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0242727 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0240733 |
| BBX | bobby sox homolog (Drosophila) | -0.0237443 |
| RPS4X | ribosomal protein S4, X-linked | -0.0236335 |
