| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetohexamide perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Acetohexamide_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.107285 |
| MKI67 | marker of proliferation Ki-67 | 0.0879622 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0791053 |
| FN1 | fibronectin 1 | 0.0715094 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0659751 |
| NAV2 | neuron navigator 2 | 0.0597347 |
| CENPF | centromere protein F, 350/400kDa | 0.0563098 |
| SMAD3 | SMAD family member 3 | 0.0483233 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0482679 |
| DIAPH3 | diaphanous-related formin 3 | 0.0459351 |
| BICC1 | BicC family RNA binding protein 1 | 0.0453356 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0445022 |
| ANLN | anillin, actin binding protein | 0.0429384 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0422892 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0406823 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0394536 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.039346 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0380689 |
| KIF4A | kinesin family member 4A | 0.0379162 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0367759 |
| DST | dystonin | 0.036492 |
| CKAP5 | cytoskeleton associated protein 5 | 0.035633 |
| TPX2 | TPX2, microtubule-associated | 0.0352243 |
| OGA | O-GlcNAcase | 0.0350149 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0348625 |
| SPAG9 | sperm associated antigen 9 | 0.0348457 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0344 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0343046 |
| TGM2 | transglutaminase 2 | 0.0329889 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0323953 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.031852 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.030219 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0296964 |
| SFTPA2 | surfactant protein A2 | 0.0290253 |
| FNIP1 | folliculin interacting protein 1 | 0.0289146 |
| HDAC9 | histone deacetylase 9 | 0.0288752 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0284713 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0283814 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0278716 |
| APP | amyloid beta (A4) precursor protein | 0.0276973 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0276169 |
| AHNAK | AHNAK nucleoprotein | 0.0272238 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0270489 |
| TMEM123 | transmembrane protein 123 | 0.0261462 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0260202 |
| CLTC | clathrin, heavy chain (Hc) | 0.0258799 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0253967 |
| FLNA | filamin A, alpha | 0.0248616 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.024611 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0244658 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0243418 |
| EZR | ezrin | 0.0238334 |
| MATR3 | matrin 3 | 0.0234301 |
| TXNRD1 | thioredoxin reductase 1 | 0.0233547 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0226694 |
| TUBB | tubulin, beta class I | 0.022541 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0222669 |
| SDC4 | syndecan 4 | 0.0219703 |
| TXNIP | thioredoxin interacting protein | 0.0218184 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0216741 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0215572 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0214813 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0210074 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.020503 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0204669 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0204494 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0202278 |
| KIF18A | kinesin family member 18A | 0.020105 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0194027 |
| KLF6 | Kruppel-like factor 6 | 0.0190641 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.019063 |
| CUL4B | cullin 4B | 0.0189761 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0189525 |
| CENPE | centromere protein E, 312kDa | 0.0189182 |
| RNF213 | ring finger protein 213 | 0.0188078 |
| TGFB2 | transforming growth factor, beta 2 | 0.0187999 |
| BPTF | bromodomain PHD finger transcription factor | 0.018678 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0186285 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0185561 |
| PRR11 | proline rich 11 | 0.0184306 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0183077 |
| HDAC8 | histone deacetylase 8 | 0.0181745 |
| LMO7 | LIM domain 7 | 0.0181601 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0181584 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0180627 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0179907 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0179581 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0178462 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0175858 |
| VMP1 | vacuole membrane protein 1 | 0.0175229 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0175208 |
| NONO | non-POU domain containing, octamer-binding | 0.017404 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0173936 |
| KYNU | kynureninase | 0.0173506 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.017219 |
| RPL3 | ribosomal protein L3 | 0.0171521 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0170935 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.017066 |
| RBM39 | RNA binding motif protein 39 | 0.0170659 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0169632 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.191943 |
| VIM | vimentin | -0.174619 |
| PDE10A | phosphodiesterase 10A | -0.135618 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.130014 |
| HLA-B | major histocompatibility complex, class I, B | -0.113754 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.101783 |
| FTL | ferritin, light polypeptide | -0.0941336 |
| TMSB10 | thymosin beta 10 | -0.0907534 |
| IER3 | immediate early response 3 | -0.0839035 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0778576 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0759396 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0740989 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0694111 |
| CD44 | CD44 molecule (Indian blood group) | -0.0690738 |
| CDH13 | cadherin 13 | -0.0601165 |
| CADM1 | cell adhesion molecule 1 | -0.0600335 |
| FRMD4A | FERM domain containing 4A | -0.0579706 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0561003 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.053297 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0509315 |
| CTSD | cathepsin D | -0.050606 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0498812 |
| B2M | beta-2-microglobulin | -0.0490011 |
| GPC6 | glypican 6 | -0.047541 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0466736 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0458136 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0454722 |
| VEGFA | vascular endothelial growth factor A | -0.0453324 |
| ADM | adrenomedullin | -0.0451207 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.041926 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.04177 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0415618 |
| HLA-A | major histocompatibility complex, class I, A | -0.0408515 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0403612 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0391018 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0386139 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0371591 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0367091 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0360796 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0356844 |
| CLMP | CXADR-like membrane protein | -0.0354967 |
| NDRG1 | N-myc downstream regulated 1 | -0.0354433 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0352971 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0349955 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0343713 |
| TPM4 | tropomyosin 4 | -0.0337542 |
| RPL23 | ribosomal protein L23 | -0.0328938 |
| RPLP1 | ribosomal protein, large, P1 | -0.0324052 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0320222 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0319616 |
| BNC2 | basonuclin 2 | -0.0317232 |
| C3 | complement component 3 | -0.0316279 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0313133 |
| RPL37A | ribosomal protein L37a | -0.0308741 |
| ENO1 | enolase 1, (alpha) | -0.0304663 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0301203 |
| NAV1 | neuron navigator 1 | -0.030045 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0299291 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0299174 |
| FBXO11 | F-box protein 11 | -0.0298121 |
| TMEM132D | transmembrane protein 132D | -0.0297798 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0297673 |
| S100A9 | S100 calcium binding protein A9 | -0.0295794 |
| RPL35A | ribosomal protein L35a | -0.0290481 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0289123 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0288569 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0283377 |
| CALR | calreticulin | -0.0280759 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0278149 |
| SEPTIN9 | septin 9 | -0.0277916 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0274944 |
| RTN4 | reticulon 4 | -0.0272822 |
| TENM2 | teneurin transmembrane protein 2 | -0.0270391 |
| GLIS3 | GLIS family zinc finger 3 | -0.0268505 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0268115 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0265071 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0260467 |
| PRR16 | proline rich 16 | -0.0260339 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0259378 |
| RPL9 | ribosomal protein L9 | -0.0258304 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0257624 |
| COL1A2 | collagen, type I, alpha 2 | -0.0255762 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0253238 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0249201 |
| LDHA | lactate dehydrogenase A | -0.0247673 |
| S100A6 | S100 calcium binding protein A6 | -0.0247542 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0246757 |
| RPS12 | ribosomal protein S12 | -0.0246539 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0246265 |
| KRT19 | keratin 19, type I | -0.0243037 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0243003 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0238225 |
| FMNL2 | formin-like 2 | -0.0235357 |
| AFF3 | AF4/FMR2 family, member 3 | -0.023081 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0228321 |
| EGR1 | early growth response 1 | -0.022616 |
| VCL | vinculin | -0.0224729 |
| MMP12 | matrix metallopeptidase 12 | -0.0223718 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.022282 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0220766 |
