| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetohexamide perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Acetohexamide_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.152499 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.141144 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.131538 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.112394 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.107745 |
| IL6 | interleukin 6 | 0.0923696 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0902497 |
| FTL | ferritin, light polypeptide | 0.0769367 |
| CD44 | CD44 molecule (Indian blood group) | 0.0765164 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0761552 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0737725 |
| POTEF | POTE ankyrin domain family, member F | 0.0670087 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0637206 |
| RND3 | Rho family GTPase 3 | 0.0629472 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0613924 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0595346 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0587349 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0575239 |
| HLA-A | major histocompatibility complex, class I, A | 0.0550847 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0547282 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0542122 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0521897 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0519907 |
| FAM13A | family with sequence similarity 13, member A | 0.0513923 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0505359 |
| ATP13A3 | ATPase type 13A3 | 0.0501623 |
| HIP1 | huntingtin interacting protein 1 | 0.0500452 |
| ENO1 | enolase 1, (alpha) | 0.0500143 |
| VIM | vimentin | 0.0487861 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.048357 |
| SEPTIN7 | septin 7 | 0.0461455 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0461071 |
| SMAD3 | SMAD family member 3 | 0.0444318 |
| RNF24 | ring finger protein 24 | 0.0434119 |
| ZNF395 | zinc finger protein 395 | 0.042842 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0424737 |
| NAV1 | neuron navigator 1 | 0.0419901 |
| COPA | coatomer protein complex, subunit alpha | 0.040937 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0407242 |
| ASPH | aspartate beta-hydroxylase | 0.0406918 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0404798 |
| JMJD1C | jumonji domain containing 1C | 0.0401897 |
| KYNU | kynureninase | 0.0401063 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0398517 |
| UBC | ubiquitin C | 0.0398183 |
| FNIP1 | folliculin interacting protein 1 | 0.0389664 |
| SEPTIN9 | septin 9 | 0.0388537 |
| B2M | beta-2-microglobulin | 0.038094 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0377036 |
| VEGFA | vascular endothelial growth factor A | 0.0373363 |
| RAB1A | RAB1A, member RAS oncogene family | 0.037142 |
| LOX | lysyl oxidase | 0.0363835 |
| CCNI | cyclin I | 0.0363828 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0363343 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.03589 |
| SPAG9 | sperm associated antigen 9 | 0.035852 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0358185 |
| CLTC | clathrin, heavy chain (Hc) | 0.0351441 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0348805 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0348373 |
| S100A10 | S100 calcium binding protein A10 | 0.0344232 |
| COG6 | component of oligomeric golgi complex 6 | 0.0340858 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0337312 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.033592 |
| CCDC88A | coiled-coil domain containing 88A | 0.0333153 |
| SEC24D | SEC24 family member D | 0.0330908 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0324652 |
| TLN1 | talin 1 | 0.032453 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0323811 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0316571 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0316499 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0316124 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0314594 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0314555 |
| FLNB | filamin B, beta | 0.0313123 |
| ANXA5 | annexin A5 | 0.0311808 |
| GOLGA4 | golgin A4 | 0.0311214 |
| VEGFC | vascular endothelial growth factor C | 0.030757 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.030735 |
| MAP1B | microtubule-associated protein 1B | 0.0306914 |
| ANXA2 | annexin A2 | 0.0305183 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0304722 |
| CDK6 | cyclin-dependent kinase 6 | 0.0301827 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0300369 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0300059 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0299668 |
| TPM3 | tropomyosin 3 | 0.0299588 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0297492 |
| WASF2 | WAS protein family, member 2 | 0.0293691 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0293437 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0292699 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.029221 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0291451 |
| YEATS2 | YEATS domain containing 2 | 0.0290429 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.028908 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0287803 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0287223 |
| SMYD3 | SET and MYND domain containing 3 | 0.0286745 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0284711 |
| USP34 | ubiquitin specific peptidase 34 | 0.0283218 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.232916 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0827075 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0759766 |
| PRSS23 | protease, serine, 23 | -0.0660169 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0625206 |
| MT1X | metallothionein 1X | -0.0608376 |
| COL1A2 | collagen, type I, alpha 2 | -0.0579509 |
| TMSB10 | thymosin beta 10 | -0.0562079 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0550827 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0531087 |
| ACTG1 | actin gamma 1 | -0.0519172 |
| VCL | vinculin | -0.0499982 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0477245 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0471702 |
| COL1A1 | collagen, type I, alpha 1 | -0.044591 |
| RRBP1 | ribosome binding protein 1 | -0.0425014 |
| CALD1 | caldesmon 1 | -0.0418793 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0396318 |
| DST | dystonin | -0.0395741 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0357708 |
| KAZN | kazrin, periplakin interacting protein | -0.0343431 |
| TNNC1 | troponin C type 1 (slow) | -0.0332865 |
| PGK1 | phosphoglycerate kinase 1 | -0.0327183 |
| THBS1 | thrombospondin 1 | -0.0325361 |
| AHNAK | AHNAK nucleoprotein | -0.0323316 |
| CALR | calreticulin | -0.0314066 |
| CDH13 | cadherin 13 | -0.0301616 |
| RBPMS | RNA binding protein with multiple splicing | -0.030002 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0299405 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0293776 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0293658 |
| FBN1 | fibrillin 1 | -0.0293632 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.02794 |
| TLE4 | transducin-like enhancer of split 4 | -0.0269854 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0252519 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0249139 |
| PCYT1A | phosphate cytidylyltransferase 1, choline, alpha | -0.024721 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0246823 |
| DENND5A | DENN/MADD domain containing 5A | -0.0245205 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0243751 |
| FAM20C | family with sequence similarity 20, member C | -0.0243391 |
| INHBA | inhibin, beta A | -0.0242407 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0240651 |
| RPS21 | ribosomal protein S21 | -0.0237522 |
| SPOCD1 | SPOC domain containing 1 | -0.0237228 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0235269 |
| COL6A2 | collagen, type VI, alpha 2 | -0.023463 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | -0.0234085 |
| NABP1 | nucleic acid binding protein 1 | -0.0230185 |
| CCM2 | cerebral cavernous malformation 2 | -0.0229096 |
| RAD51B | RAD51 paralog B | -0.0228581 |
| LMNA | lamin A/C | -0.0227517 |
| HLA-C | major histocompatibility complex, class I, C | -0.0222724 |
| MCL1 | myeloid cell leukemia 1 | -0.0218656 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | -0.0217986 |
| RSRP1 | arginine/serine-rich protein 1 | -0.0217639 |
| IPO9 | importin 9 | -0.021603 |
| RORA | RAR-related orphan receptor A | -0.0215972 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0212191 |
| CUL1 | cullin 1 | -0.0210631 |
| FN1 | fibronectin 1 | -0.0208768 |
| PLEC | plectin | -0.0206864 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0206659 |
| EFHD2 | EF-hand domain family, member D2 | -0.0206399 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0205396 |
| PLCB4 | phospholipase C, beta 4 | -0.0203997 |
| OAF | OAF homolog (Drosophila) | -0.0203964 |
| DIAPH2 | diaphanous-related formin 2 | -0.0203245 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0203058 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | -0.020191 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0201196 |
| NEK10 | NIMA-related kinase 10 | -0.0201149 |
| TOP1 | topoisomerase (DNA) I | -0.0200891 |
| PLXNA3 | plexin A3 | -0.0200639 |
| NAV3 | neuron navigator 3 | -0.0199257 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0199136 |
| DLG5 | discs, large homolog 5 (Drosophila) | -0.0196607 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.0195206 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0195025 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0194241 |
| PCNX2 | pecanex 2 | -0.0193955 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.01933 |
| COL5A1 | collagen, type V, alpha 1 | -0.0191972 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0191944 |
| JAZF1 | JAZF zinc finger 1 | -0.0191343 |
| KLF12 | Kruppel-like factor 12 | -0.0191239 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0191181 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0190809 |
| TUT4 | terminal uridylyl transferase 4 | -0.0190144 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.018923 |
| CD63 | CD63 molecule | -0.0189106 |
| HEATR5A | HEAT repeat containing 5A | -0.0189079 |
| TENM3 | teneurin transmembrane protein 3 | -0.0188727 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0188349 |
| ATM | ATM serine/threonine kinase | -0.0188156 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0187891 |
| EBF1 | early B-cell factor 1 | -0.0187891 |
| FUS | FUS RNA binding protein | -0.0186745 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0186219 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0185969 |
