| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Acetohexamide perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Acetohexamide_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.263854 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0964923 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0738782 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0701817 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.067484 |
| FMNL2 | formin-like 2 | 0.0615301 |
| DST | dystonin | 0.0613676 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0552919 |
| PRKCA | protein kinase C, alpha | 0.0552495 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0544048 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0514385 |
| ATXN1 | ataxin 1 | 0.0510943 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.050944 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0496471 |
| HMGA2 | high mobility group AT-hook 2 | 0.0473797 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0461311 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0456309 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0455563 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0442643 |
| SQSTM1 | sequestosome 1 | 0.0439003 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0437665 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0437663 |
| INTS6 | integrator complex subunit 6 | 0.0434905 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0395361 |
| RUNX1 | runt-related transcription factor 1 | 0.0392309 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.038392 |
| ANXA2 | annexin A2 | 0.0378924 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.037882 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0373642 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0357151 |
| VIM | vimentin | 0.0355632 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0354597 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0354512 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0348075 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0342414 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0332747 |
| ANXA1 | annexin A1 | 0.03266 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0325579 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0320741 |
| DENND4A | DENN/MADD domain containing 4A | 0.0320292 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0319058 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0311071 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0310007 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0302253 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0298905 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0287455 |
| ANO6 | anoctamin 6 | 0.0285546 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0282105 |
| POTEF | POTE ankyrin domain family, member F | 0.027826 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0278213 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0276766 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0276416 |
| KIF5B | kinesin family member 5B | 0.0275344 |
| PKM | pyruvate kinase, muscle | 0.026714 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0266559 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.026522 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0264813 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0261637 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0258438 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0258309 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0253297 |
| SVIL | supervillin | 0.0252704 |
| SPAG9 | sperm associated antigen 9 | 0.0252667 |
| SATB2 | SATB homeobox 2 | 0.0251433 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0250652 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0247927 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0245717 |
| UTRN | utrophin | 0.0245266 |
| GOLGB1 | golgin B1 | 0.0243916 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0242579 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0240659 |
| DTNA | dystrobrevin, alpha | 0.0238335 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0236943 |
| GOLGA4 | golgin A4 | 0.0234585 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.023384 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0230822 |
| YBX3 | Y box binding protein 3 | 0.0228873 |
| COL5A1 | collagen, type V, alpha 1 | 0.0226804 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0225626 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0224399 |
| CD44 | CD44 molecule (Indian blood group) | 0.022438 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0222649 |
| JMJD1C | jumonji domain containing 1C | 0.0221832 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0221386 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0220886 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0218791 |
| OXSR1 | oxidative stress responsive 1 | 0.0217484 |
| CLIC4 | chloride intracellular channel 4 | 0.0216576 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0215897 |
| UBC | ubiquitin C | 0.0212693 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0212308 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0212006 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0211994 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0211733 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0210707 |
| RIGI | RNA sensor RIG-I | 0.0208257 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0208006 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0205935 |
| EGFR | epidermal growth factor receptor | 0.0205162 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0204612 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TAS2R14 | taste receptor, type 2, member 14 | -0.0229789 |
| GPC6 | glypican 6 | -0.0229765 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0223601 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0222272 |
| ACER3 | alkaline ceramidase 3 | -0.0209648 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0206754 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0199329 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0186483 |
| TCERG1 | transcription elongation regulator 1 | -0.0179898 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0174977 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0172259 |
| KIAA1328 | KIAA1328 | -0.0171027 |
| TGFBR1 | transforming growth factor, beta receptor 1 | -0.0155006 |
| GOLT1B | golgi transport 1B | -0.0154828 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0153664 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.015026 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0148504 |
| KIF4A | kinesin family member 4A | -0.0148254 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0146027 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0145537 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0144128 |
| YEATS2 | YEATS domain containing 2 | -0.0143824 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | -0.0143422 |
| LDHA | lactate dehydrogenase A | -0.0142546 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0141725 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0140665 |
| TP53 | tumor protein p53 | -0.0138599 |
| ZNF267 | zinc finger protein 267 | -0.0135516 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0135168 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0132855 |
| RAD21 | RAD21 homolog (S. pombe) | -0.013276 |
| TXN2 | thioredoxin 2 | -0.0132751 |
| ATXN3 | ataxin 3 | -0.013254 |
| THOC2 | THO complex 2 | -0.0131452 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) | -0.0131007 |
| DIS3L2 | DIS3 like 3'-5' exoribonuclease 2 | -0.0130399 |
| FBXO34 | F-box protein 34 | -0.0130212 |
| NOP58 | NOP58 ribonucleoprotein | -0.0129205 |
| TLE5 | TLE family member 5, transcriptional modulator | -0.0127333 |
| FUBP3 | far upstream element (FUSE) binding protein 3 | -0.0126836 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0126234 |
| RPS27A | ribosomal protein S27a | -0.0126016 |
| NUP98 | nucleoporin 98kDa | -0.0125944 |
| ANO10 | anoctamin 10 | -0.0125732 |
| ARMC1 | armadillo repeat containing 1 | -0.0125461 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0124995 |
| SRPK1 | SRSF protein kinase 1 | -0.0124696 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0123931 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0123891 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0123579 |
| TUBB6 | tubulin, beta 6 class V | -0.0123393 |
| KPNA6 | karyopherin alpha 6 (importin alpha 7) | -0.0123173 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0122862 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.0122836 |
| FASTKD2 | FAST kinase domains 2 | -0.0122733 |
| HDLBP | high density lipoprotein binding protein | -0.012171 |
| SLC25A2 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 | -0.0120923 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0120756 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0120036 |
| CREBBP | CREB binding protein | -0.0119803 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.0119656 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0119442 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0118229 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0118189 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0117975 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0117582 |
| ILK | integrin-linked kinase | -0.0117569 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0116544 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0115729 |
| FANCI | Fanconi anemia, complementation group I | -0.0115651 |
| SP3 | Sp3 transcription factor | -0.0115616 |
| TPM4 | tropomyosin 4 | -0.0115122 |
| RPL35A | ribosomal protein L35a | -0.0114839 |
| CENPK | centromere protein K | -0.011472 |
| TNPO1 | transportin 1 | -0.0114321 |
| FANCL | Fanconi anemia, complementation group L | -0.011415 |
| PDCD10 | programmed cell death 10 | -0.0113842 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | -0.0113703 |
| ZNF717 | zinc finger protein 717 | -0.0113291 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0113033 |
| FPGS | folylpolyglutamate synthase | -0.0112673 |
| KIF13A | kinesin family member 13A | -0.0112657 |
| RNF169 | ring finger protein 169 | -0.0112344 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0111678 |
| COG5 | component of oligomeric golgi complex 5 | -0.0111311 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | -0.0110946 |
| PPA2 | pyrophosphatase (inorganic) 2 | -0.0110853 |
| ICA1 | islet cell autoantigen 1, 69kDa | -0.0110663 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.0110655 |
| NEK7 | NIMA-related kinase 7 | -0.0109945 |
| TMEM87A | transmembrane protein 87A | -0.0109705 |
| FANCC | Fanconi anemia, complementation group C | -0.0108742 |
| KIF3A | kinesin family member 3A | -0.0108496 |
| COX20 | COX20 cytochrome c oxidase assembly factor | -0.0107564 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | -0.0107413 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0105939 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0105937 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0105138 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0104255 |
| NUP54 | nucleoporin 54kDa | -0.0104115 |