Acth-Secreting Pituitary Adenoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A functioning pituitary adenoma that characterized by excess cortisol a primary cause of Cushing's syndrome. (Human Disease Ontology, DOID_7004)
External Link https://www.disgenet.org/browser/0/1/0/C1306214
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Genes

63 genes associated with the disease Acth-Secreting Pituitary Adenoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AIP aryl hydrocarbon receptor interacting protein
BMP4 bone morphogenetic protein 4
BRAF B-Raf proto-oncogene, serine/threonine kinase
CCND1 cyclin D1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK3 cyclin-dependent kinase 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CIRBP cold inducible RNA binding protein
CRH corticotropin releasing hormone
CRHBP corticotropin releasing hormone binding protein
CRHR1 corticotropin releasing hormone receptor 1
DCTN6 dynactin 6
DRD2 dopamine receptor D2
EGFR epidermal growth factor receptor
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GH1 growth hormone 1
GHRH growth hormone releasing hormone
GNAS GNAS complex locus
GPR101 G protein-coupled receptor 101
HDAC2 histone deacetylase 2
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IFI27 interferon, alpha-inducible protein 27
IFNG interferon, gamma
IGFBP3 insulin-like growth factor binding protein 3
IL6 interleukin 6
KLK10 kallikrein-related peptidase 10
LIFR leukemia inhibitory factor receptor alpha
MAPK3 mitogen-activated protein kinase 3
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MEN1 multiple endocrine neoplasia I
MGC57346-CRHR1 MGC57346-CRHR1 readthrough
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae)
PCSK1 proprotein convertase subtilisin/kexin type 1
PCSK2 proprotein convertase subtilisin/kexin type 2
POMC proopiomelanocortin
POU4F1 POU class 4 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PROP1 PROP paired-like homeobox 1
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
SFRP2 secreted frizzled-related protein 2
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
SST somatostatin
SSTR2 somatostatin receptor 2
SSTR3 somatostatin receptor 3
SSTR5 somatostatin receptor 5
TBX19 T-box 19
TICAM2 toll-like receptor adaptor molecule 2
TIMP3 TIMP metallopeptidase inhibitor 3
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TP53 tumor protein p53
TXNIP thioredoxin interacting protein
USP48 ubiquitin specific peptidase 48
USP8 ubiquitin specific peptidase 8