Acute Gvh Disease Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0856825
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Genes

253 genes associated with the disease Acute Gvh Disease in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACACA acetyl-CoA carboxylase alpha
AHR aryl hydrocarbon receptor
ALB albumin
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
APC adenomatous polyposis coli
AREG amphiregulin
ARHGAP45 Rho GTPase activating protein 45
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ASCC1 activating signal cointegrator 1 complex subunit 1
ATM ATM serine/threonine kinase
ATN1 atrophin 1
AURKA aurora kinase A
B3GAT1 beta-1,3-glucuronyltransferase 1
BCHE butyrylcholinesterase
BCL6 B-cell CLL/lymphoma 6
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMS1 BMS1 ribosome biogenesis factor
BPI bactericidal/permeability-increasing protein
C1ORF228 chromosome 1 open reading frame 228
C3 complement component 3
C3AR1 complement component 3a receptor 1
C5AR1 complement component 5a receptor 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL5 chemokine (C-C motif) ligand 5
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR7 chemokine (C-C motif) receptor 7
CD14 CD14 molecule
CD19 CD19 molecule
CD274 CD274 molecule
CD276 CD276 molecule
CD28 CD28 molecule
CD34 CD34 molecule
CD38 CD38 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD52 CD52 molecule
CD83 CD83 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLEC7A C-type lectin domain family 7, member A
COMMD3-BMI1 COMMD3-BMI1 readthrough
CRAMP1L Crm, cramped-like (Drosophila)
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR3 chemokine (C-X-C motif) receptor 3
CYLD cylindromatosis (turban tumor syndrome)
DAAM2 dishevelled associated activator of morphogenesis 2
DEFA5 defensin, alpha 5, Paneth cell-specific
DHFR dihydrofolate reductase
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DOCK11 dedicator of cytokinesis 11
EBNA1BP2 EBNA1 binding protein 2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
FANCB Fanconi anemia, complementation group B
FANCD2 Fanconi anemia, complementation group D2
FBXO3 F-box protein 3
FCRL3 Fc receptor-like 3
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
FOXP3 forkhead box P3
FST follistatin
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FUT2 fucosyltransferase 2 (secretor status included)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAS6 growth arrest-specific 6
GEM GTP binding protein overexpressed in skeletal muscle
GJB2 gap junction protein, beta 2, 26kDa
GLCCI1 glucocorticoid induced 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HCST hematopoietic cell signal transducer
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-E major histocompatibility complex, class I, E
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HPSE heparanase
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1B heat shock 70kDa protein 1B
HSPA1L heat shock 70kDa protein 1-like
HSPA4 heat shock 70kDa protein 4
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNG interferon, gamma
IL10 interleukin 10
IL10RB interleukin 10 receptor, beta
IL17A interleukin 17A
IL17RA interleukin 17 receptor A
IL17RC interleukin 17 receptor C
IL18 interleukin 18
IL18RAP interleukin 18 receptor accessory protein
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL22 interleukin 22
IL23R interleukin 23 receptor
IL27RA interleukin 27 receptor, alpha
IL2RA interleukin 2 receptor, alpha
IL32 interleukin 32
IL33 interleukin 33
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IL7 interleukin 7
IL7R interleukin 7 receptor
IL9 interleukin 9
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INSR insulin receptor
ISG20 interferon stimulated exonuclease gene 20kDa
ITFG1 integrin alpha FG-GAP repeat containing 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB7 integrin, beta 7
JAK2 Janus kinase 2
KAT5 K(lysine) acetyltransferase 5
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KLRC4-KLRK1 KLRC4-KLRK1 readthrough
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2A lysine (K)-specific methyltransferase 2A
KRT15 keratin 15, type I
LAMC2 laminin, gamma 2
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LTA lymphotoxin alpha
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MBTPS1 membrane-bound transcription factor peptidase, site 1
METTL8 methyltransferase like 8
MICA MHC class I polypeptide-related sequence A
MPO myeloperoxidase
MSC musculin
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYD88 myeloid differentiation primary response 88
NCAM1 neural cell adhesion molecule 1
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLGN4Y neuroligin 4, Y-linked
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRM nurim (nuclear envelope membrane protein)
OAT ornithine aminotransferase
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PC pyruvate carboxylase
PECAM1 platelet/endothelial cell adhesion molecule 1
PI3 peptidase inhibitor 3, skin-derived
PLG plasminogen
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PSG1 pregnancy specific beta-1-glycoprotein 1
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PTAFR platelet-activating factor receptor
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTX3 pentraxin 3, long
PUM3 pumilio RNA binding family member 3
QPCT glutaminyl-peptide cyclotransferase
RABEPK Rab9 effector protein with kelch motifs
RBM45 RNA binding motif protein 45
REG3A regenerating islet-derived 3 alpha
RPSA ribosomal protein SA
S1PR1 sphingosine-1-phosphate receptor 1
SCT secretin
SELL selectin L
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SIRT1 sirtuin 1
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SMAD3 SMAD family member 3
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK11 serine/threonine kinase 11
SUFU suppressor of fused homolog (Drosophila)
TAPBP TAP binding protein (tapasin)
TBCE tubulin folding cofactor E
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
TIGIT T cell immunoreceptor with Ig and ITIM domains
TIPRL TOR signaling pathway regulator
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR6 toll-like receptor 6
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNMD tenomodulin
TP53 tumor protein p53
TP63 tumor protein p63
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TSHZ1 teashirt zinc finger homeobox 1
TYMS thymidylate synthetase
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
UTS2R urotensin 2 receptor
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIM vimentin
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)
VSIR V-set immunoregulatory receptor
VTCN1 V-set domain containing T cell activation inhibitor 1
VWF von Willebrand factor