Acute Interstitial Pneumonia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A idiopathic interstitial pneumonia which develops suddenly and is severe. Initially, the lung shows edema, hyaline membranes, and interstitial acute inflammation. Later,it develops loose organizing fibrosis, mostly within alveolar septa and type II pneumocyte hyperplasia. Fever, cough, and difficulty breathing develop over 1 to 2 weeks, typically progressing to acute respiratory failure. (Human Disease Ontology, DOID_2800)
External Link https://www.disgenet.org/browser/0/1/0/C1279945
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Genes

79 genes associated with the disease Acute Interstitial Pneumonia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
AIP aryl hydrocarbon receptor interacting protein
AMY2A amylase, alpha 2A (pancreatic)
APOA2 apolipoprotein A-II
ARSA arylsulfatase A
B2M beta-2-microglobulin
CA2 carbonic anhydrase II
CALCB calcitonin-related polypeptide beta
CCR2 chemokine (C-C motif) receptor 2
CD274 CD274 molecule
CELA1 chymotrypsin-like elastase family, member 1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR5 chemokine (C-X-C motif) receptor 5
DEGS1 delta(4)-desaturase, sphingolipid 1
DOCK3 dedicator of cytokinesis 3
EGFR epidermal growth factor receptor
ENO1 enolase 1, (alpha)
FCRL3 Fc receptor-like 3
FECH ferrochelatase
FOXP3 forkhead box P3
HLA-A major histocompatibility complex, class I, A
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-E major histocompatibility complex, class I, E
HMBS hydroxymethylbilane synthase
HSPE1 heat shock 10kDa protein 1
IDO1 indoleamine 2,3-dioxygenase 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IL10 interleukin 10
IL13 interleukin 13
IL21 interleukin 21
IL22 interleukin 22
IL33 interleukin 33
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KNTC1 kinetochore associated 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT20 keratin 20, type I
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LOC102724971 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LOC105379528 Ig heavy chain V region 5A-like
LTA lymphotoxin alpha
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MED1 mediator complex subunit 1
MMRN1 multimerin 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MST1 macrophage stimulating 1
MT-ATP8 ATP synthase F0 subunit 8
MVD mevalonate (diphospho) decarboxylase
NGF nerve growth factor (beta polypeptide)
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
PDPN podoplanin
PEBP1 phosphatidylethanolamine binding protein 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLAT plasminogen activator, tissue
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPOX protoporphyrinogen oxidase
PRSS1 protease, serine, 1 (trypsin 1)
SCT secretin
SEC14L2 SEC14-like 2 (S. cerevisiae)
SKI SKI proto-oncogene
SMAD4 SMAD family member 4
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SST somatostatin
TFPI2 tissue factor pathway inhibitor 2
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
THY1 Thy-1 cell surface antigen
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TP53 tumor protein p53
UROD uroporphyrinogen decarboxylase