Acute Megakaryocytic Leukemias Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0023462
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Genes

153 genes associated with the disease Acute Megakaryocytic Leukemias in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTB actin, beta
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ANGPT1 angiopoietin 1
ANK1 ankyrin 1, erythrocytic
ANPEP alanyl (membrane) aminopeptidase
AP3B1 adaptor-related protein complex 3, beta 1 subunit
APCS amyloid P component, serum
APOC1 apolipoprotein C-I
APOC2 apolipoprotein C-II
ARC activity-regulated cytoskeleton-associated protein
ATM ATM serine/threonine kinase
AURKA aurora kinase A
BIRC5 baculoviral IAP repeat containing 5
BPTF bromodomain PHD finger transcription factor
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBS cystathionine-beta-synthase
CCDC28A coiled-coil domain containing 28A
CCN2 cellular communication network factor 2
CCR7 chemokine (C-C motif) receptor 7
CD36 CD36 molecule (thrombospondin receptor)
CD38 CD38 molecule
CD8A CD8a molecule
CDA cytidine deaminase
CLPTM1L CLPTM1-like
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
CRP C-reactive protein, pentraxin-related
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CXCL9 chemokine (C-X-C motif) ligand 9
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DLC1 DLC1 Rho GTPase activating protein
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EPO erythropoietin
EPOR erythropoietin receptor
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
ETV6 ets variant 6
EVPL envoplakin
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
FANCB Fanconi anemia, complementation group B
FGFR1 fibroblast growth factor receptor 1
FLT3 fms-related tyrosine kinase 3
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FXR2 fragile X mental retardation, autosomal homolog 2
G6PD glucose-6-phosphate dehydrogenase
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GATA1 GATA binding protein 1 (globin transcription factor 1)
GFI1B growth factor independent 1B transcription repressor
GLI1 GLI family zinc finger 1
GLIS1 GLIS family zinc finger 1
GLIS2 GLIS family zinc finger 2
GLIS3 GLIS family zinc finger 3
GNLY granulysin
GP1BA glycoprotein Ib (platelet), alpha polypeptide
HBG1 hemoglobin, gamma A
HBG2 hemoglobin, gamma G
HOXC5 homeobox C5
IL11 interleukin 11
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL3 interleukin 3
IL6 interleukin 6
IL6R interleukin 6 receptor
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KDM5A lysine (K)-specific demethylase 5A
KMT2A lysine (K)-specific methyltransferase 2A
LOC102724560 cystathionine beta-synthase
LOX lysyl oxidase
MAL mal, T-cell differentiation protein
MECOM MDS1 and EVI1 complex locus
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MNX1 motor neuron and pancreas homeobox 1
MPL MPL proto-oncogene, thrombopoietin receptor
MPO myeloperoxidase
MRTFA myocardin related transcription factor A
MRTFB myocardin related transcription factor B
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYH11 myosin, heavy chain 11, smooth muscle
MYOCD myocardin
NCAM1 neural cell adhesion molecule 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUP98 nucleoporin 98kDa
PAX8 paired box 8
PDGFB platelet-derived growth factor beta polypeptide
PF4 platelet factor 4
PFN1 profilin 1
PFN2 profilin 2
PICALM phosphatidylinositol binding clathrin assembly protein
PML promyelocytic leukemia
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRAME preferentially expressed antigen in melanoma
PRB1 proline-rich protein BstNI subfamily 1
PTEN phosphatase and tensin homolog
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAP1A RAP1A, member of RAS oncogene family
RBM15 RNA binding motif protein 15
RBM6 RNA binding motif protein 6
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RNASE3 ribonuclease, RNase A family, 3
RPS19 ribosomal protein S19
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SCIN scinderin
SH2D1A SH2 domain containing 1A
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SNAP91 synaptosomal-associated protein, 91kDa
SPEN spen family transcriptional repressor
SPHK1 sphingosine kinase 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SUMO3 small ubiquitin-like modifier 3
TEK TEK tyrosine kinase, endothelial
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
THPO thrombopoietin
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TMEM241 transmembrane protein 241
TNC tenascin C
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNS1 tensin 1
TP53 tumor protein p53
TRIB1 tribbles pseudokinase 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIPR1 vasoactive intestinal peptide receptor 1
VWF von Willebrand factor
ZNF587B zinc finger protein 587B