Acute Myeloid Leukaemia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0522631
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Genes

107 genes associated with the disease Acute Myeloid Leukaemia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AKT1 v-akt murine thymoma viral oncogene homolog 1
AMACR alpha-methylacyl-CoA racemase
ARR3 arrestin 3, retinal (X-arrestin)
ASRGL1 asparaginase like 1
BCL10 B-cell CLL/lymphoma 10
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
CARTPT CART prepropeptide
CASR calcium-sensing receptor
CBFB core-binding factor, beta subunit
CCL28 chemokine (C-C motif) ligand 28
CCR7 chemokine (C-C motif) receptor 7
CD19 CD19 molecule
CD33 CD33 molecule
CD34 CD34 molecule
CD47 CD47 molecule
CDK9 cyclin-dependent kinase 9
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHEK1 checkpoint kinase 1
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
CPA3 carboxypeptidase A3 (mast cell)
CPOX coproporphyrinogen oxidase
CREBBP CREB binding protein
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CXADR coxsackie virus and adenovirus receptor
CXCL9 chemokine (C-X-C motif) ligand 9
DCK deoxycytidine kinase
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EBP emopamil binding protein (sterol isomerase)
ELL elongation factor RNA polymerase II
ETV6 ets variant 6
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FANCB Fanconi anemia, complementation group B
FAS Fas cell surface death receptor
FGFR1 fibroblast growth factor receptor 1
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
GATA2 GATA binding protein 2
HLA-A major histocompatibility complex, class I, A
HMGA2 high mobility group AT-hook 2
HMGB1 high mobility group box 1
HOXB9 homeobox B9
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IDUA iduronidase, alpha-L-
IL2 interleukin 2
IL3RA interleukin 3 receptor, alpha (low affinity)
KAT6A K(lysine) acetyltransferase 6A
KLRC4-KLRK1 KLRC4-KLRK1 readthrough
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
MAP2K7 mitogen-activated protein kinase kinase 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECOM MDS1 and EVI1 complex locus
MLF1 myeloid leukemia factor 1
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MME membrane metallo-endopeptidase
MN1 meningioma (disrupted in balanced translocation) 1
MPO myeloperoxidase
MT1E metallothionein 1E
MTF2 metal response element binding transcription factor 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYH11 myosin, heavy chain 11, smooth muscle
NCR1 natural cytotoxicity triggering receptor 1
NCR2 natural cytotoxicity triggering receptor 2
NCR3 natural cytotoxicity triggering receptor 3
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR1I3 nuclear receptor subfamily 1, group I, member 3
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUP98 nucleoporin 98kDa
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PHF6 PHD finger protein 6
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCH protein kinase C, eta
PROM1 prominin 1
PTEN phosphatase and tensin homolog
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RB1 retinoblastoma 1
RET ret proto-oncogene
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
RUNX3 runt-related transcription factor 3
SIRPA signal-regulatory protein alpha
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SRSF2 serine/arginine-rich splicing factor 2
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBX22 T-box 22
TET2 tet methylcytosine dioxygenase 2
TP53 tumor protein p53
TRIM13 tripartite motif containing 13
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZMYND11 zinc finger, MYND-type containing 11