Acute Myeloid Leukemia_LAML_TCGA-AB-2843-03A-01T-0736-13 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Acute Myeloid Leukemia_LAML (The Cancer Genome Atlas)
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385 genes with high or low expression in Acute Myeloid Leukemia_LAML_TCGA-AB-2843-03A-01T-0736-13 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACHE acetylcholinesterase (Yt blood group)
ACY3 aminoacylase 3
ADAM29 ADAM metallopeptidase domain 29
ADAR adenosine deaminase, RNA-specific
ADD1 adducin 1 (alpha)
AGFG2 ArfGAP with FG repeats 2
ALAD aminolevulinate dehydratase
ALOX15 arachidonate 15-lipoxygenase
AMIGO2 adhesion molecule with Ig-like domain 2
AP3D1 adaptor-related protein complex 3, delta 1 subunit
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ASB2 ankyrin repeat and SOCS box containing 2
ASCL1 achaete-scute family bHLH transcription factor 1
ATP10A ATPase, class V, type 10A
AUNIP aurora kinase A and ninein interacting protein
AVPR2 arginine vasopressin receptor 2
B9D1 B9 protein domain 1
BCHE butyrylcholinesterase
BHLHA15 basic helix-loop-helix family, member a15
BIRC5 baculoviral IAP repeat containing 5
BLVRB biliverdin reductase B
BMF Bcl2 modifying factor
BRS3 bombesin-like receptor 3
C12ORF74 chromosome 12 open reading frame 74
C19ORF57 chromosome 19 open reading frame 57
C1ORF127 chromosome 1 open reading frame 127
C20ORF195 chromosome 20 open reading frame 195
C2ORF73 chromosome 2 open reading frame 73
C5ORF60 chromosome 5 open reading frame 60
C7ORF65 chromosome 7 open reading frame 65
C8ORF74 chromosome 8 open reading frame 74
C9ORF172 chromosome 9 open reading frame 172
CABLES2 Cdk5 and Abl enzyme substrate 2
CALHM1 calcium homeostasis modulator 1
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAPN5 calpain 5
CARD11 caspase recruitment domain family, member 11
CCL13 chemokine (C-C motif) ligand 13
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCR3 chemokine (C-C motif) receptor 3
CCR8 chemokine (C-C motif) receptor 8
CD1C CD1c molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDC20 cell division cycle 20
CDT1 chromatin licensing and DNA replication factor 1
CELF3 CUGBP, Elav-like family member 3
CHAD chondroadherin
CHRD chordin
CLCN5 chloride channel, voltage-sensitive 5
CLIC3 chloride intracellular channel 3
CLIC6 chloride intracellular channel 6
CLLU1 chronic lymphocytic leukemia up-regulated 1
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
CMTR1 cap methyltransferase 1
CNTN5 contactin 5
COG4 component of oligomeric golgi complex 4
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CPA2 carboxypeptidase A2 (pancreatic)
CPED1 cadherin-like and PC-esterase domain containing 1
CPNE5 copine V
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CREB3L1 cAMP responsive element binding protein 3-like 1
CREBBP CREB binding protein
CRIP3 cysteine-rich protein 3
CSF1R colony stimulating factor 1 receptor
CSMD3 CUB and Sushi multiple domains 3
CTSE cathepsin E
CXCR3 chemokine (C-X-C motif) receptor 3
CYMP chymosin pseudogene
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCAF11 DDB1 and CUL4 associated factor 11
DDN dendrin
DDR1 discoidin domain receptor tyrosine kinase 1
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DEGS2 delta(4)-desaturase, sphingolipid 2
DGKK diacylglycerol kinase, kappa
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DMBX1 diencephalon/mesencephalon homeobox 1
DMPK dystrophia myotonica-protein kinase
DMWD dystrophia myotonica, WD repeat containing
DOCK6 dedicator of cytokinesis 6
DOCK9 dedicator of cytokinesis 9
DPP4 dipeptidyl-peptidase 4
DTX3L deltex 3 like, E3 ubiquitin ligase
E2F2 E2F transcription factor 2
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ENHO energy homeostasis associated
EPN2 epsin 2
EPSTI1 epithelial stromal interaction 1 (breast)
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERMN ermin, ERM-like protein
ERN2 endoplasmic reticulum to nucleus signaling 2
EXO1 exonuclease 1
FA2H fatty acid 2-hydroxylase
FAM178B family with sequence similarity 178, member B
FAM181A family with sequence similarity 181, member A
FAM181A-AS1 FAM181A antisense RNA 1
FAM224B family with sequence similarity 224, member B (non-protein coding)
FAM69A family with sequence similarity 69, member A
FAM83F family with sequence similarity 83, member F
FAM92A1 family with sequence similarity 92, member A1
FANCE Fanconi anemia, complementation group E
FCMR Fc fragment of IgM receptor
FGF19 fibroblast growth factor 19
FKBPL FK506 binding protein like
FLT4 fms-related tyrosine kinase 4
FMO6P flavin containing monooxygenase 6 pseudogene
FMOD fibromodulin
FOXA2 forkhead box A2
FOXE3 forkhead box E3
FRMD1 FERM domain containing 1
GAS6 growth arrest-specific 6
GATA4 GATA binding protein 4
GCSAM germinal center-associated, signaling and motility
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GLYATL1 glycine-N-acyltransferase-like 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial
GPR146 G protein-coupled receptor 146
GPR19 G protein-coupled receptor 19
GPR3 G protein-coupled receptor 3
GPR62 G protein-coupled receptor 62
GRIK3 glutamate receptor, ionotropic, kainate 3
GRK5 G protein-coupled receptor kinase 5
GRM7 glutamate receptor, metabotropic 7
HABP2 hyaluronan binding protein 2
HBA2 hemoglobin, alpha 2
HBG1 hemoglobin, gamma A
HBG2 hemoglobin, gamma G
HBZ hemoglobin, zeta
HCFC1 host cell factor C1
HDAC7 histone deacetylase 7
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HGC6.3 uncharacterized LOC100128124
HHLA2 HERV-H LTR-associating 2
HILS1 histone linker H1 domain, spermatid-specific 1, pseudogene
HIPK4 homeodomain interacting protein kinase 4
HMGA1 high mobility group AT-hook 1
HNF1A HNF1 homeobox A
HRASLS2 HRAS-like suppressor 2
HRH1 histamine receptor H1
ICT1 immature colon carcinoma transcript 1
IFI35 interferon-induced protein 35
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
IFNA4 interferon, alpha 4
IL13 interleukin 13
IL2RA interleukin 2 receptor, alpha
IRF7 interferon regulatory factor 7
ISG15 ISG15 ubiquitin-like modifier
ISG20 interferon stimulated exonuclease gene 20kDa
ITGB7 integrin, beta 7
KBTBD12 kelch repeat and BTB (POZ) domain containing 12
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNK18 potassium channel, two pore domain subfamily K, member 18
KIAA0040 KIAA0040
KIAA1614 KIAA1614
KIF26B kinesin family member 26B
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KISS1 KiSS-1 metastasis-suppressor
KLHDC8A kelch domain containing 8A
KLHL14 kelch-like family member 14
KRT13 keratin 13, type I
KRT81 keratin 81, type II
KRTAP7-1 keratin associated protein 7-1 (gene/pseudogene)
LHB luteinizing hormone beta polypeptide
LINC00261 long intergenic non-protein coding RNA 261
LINC00475 long intergenic non-protein coding RNA 475
LOC100133669 uncharacterized LOC100133669
LOC283731 uncharacterized LOC283731
LOC284632 uncharacterized LOC284632
LOC644936 actin, beta pseudogene
LRRK1 leucine-rich repeat kinase 1
LY9 lymphocyte antigen 9
MAGEB2 melanoma antigen family B2
MAGED4B melanoma antigen family D4B
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MBOAT4 membrane bound O-acyltransferase domain containing 4
MCCD1 mitochondrial coiled-coil domain 1
MCM2 minichromosome maintenance complex component 2
MCM5 minichromosome maintenance complex component 5
MED24 mediator complex subunit 24
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MOV10 Mov10 RISC complex RNA helicase
MROH9 maestro heat-like repeat family member 9
MRPL14 mitochondrial ribosomal protein L14
MST1R macrophage stimulating 1 receptor
MTA3 metastasis associated 1 family, member 3
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
MYH13 myosin, heavy chain 13, skeletal muscle
N4BP1 NEDD4 binding protein 1
NCOR2 nuclear receptor corepressor 2
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
NEUROD4 neuronal differentiation 4
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NOS3 nitric oxide synthase 3 (endothelial cell)
NOXO1 NADPH oxidase organizer 1
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NUP93 nucleoporin 93kDa
NXN nucleoredoxin
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OASL 2'-5'-oligoadenylate synthetase-like
OPRM1 opioid receptor, mu 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR1E1 olfactory receptor, family 1, subfamily E, member 1
OR2T2 olfactory receptor, family 2, subfamily T, member 2
OR2T3 olfactory receptor, family 2, subfamily T, member 3
OR3A3 olfactory receptor, family 3, subfamily A, member 3
OR52E2 olfactory receptor, family 52, subfamily E, member 2
ORC1 origin recognition complex, subunit 1
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAGE2 P antigen family, member 2 (prostate associated)
PAGE2B P antigen family, member 2B
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARP10 poly (ADP-ribose) polymerase family, member 10
PARP12 poly (ADP-ribose) polymerase family, member 12
PARP9 poly (ADP-ribose) polymerase family, member 9
PCDH1 protocadherin 1
PCDHB5 protocadherin beta 5
PCED1B PC-esterase domain containing 1B
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PHOSPHO1 phosphatase, orphan 1
PIGR polymeric immunoglobulin receptor
PIWIL3 piwi-like RNA-mediated gene silencing 3
PKDCC protein kinase domain containing, cytoplasmic
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLA2G5 phospholipase A2, group V
PLAC1 placenta-specific 1
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
PLK1 polo-like kinase 1
PLXNA1 plexin A1
POU2AF1 POU class 2 associating factor 1
PRAME preferentially expressed antigen in melanoma
PRF1 perforin 1 (pore forming protein)
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKCA protein kinase C, alpha
PRR15L proline rich 15-like
PTK2 protein tyrosine kinase 2
PXDNL peroxidasin-like
PYHIN1 pyrin and HIN domain family, member 1
RASEF RAS and EF-hand domain containing
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
RBM38 RNA binding motif protein 38
REG4 regenerating islet-derived family, member 4
RGS7 regulator of G-protein signaling 7
RHOBTB2 Rho-related BTB domain containing 2
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RNF213 ring finger protein 213
RNF222 ring finger protein 222
RNFT2 ring finger protein, transmembrane 2
RORC RAR-related orphan receptor C
RP1L1 retinitis pigmentosa 1-like 1
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RSAD2 radical S-adenosyl methionine domain containing 2
RSPH9 radial spoke head 9 homolog (Chlamydomonas)
RUNDC3A RUN domain containing 3A
RXFP1 relaxin/insulin-like family peptide receptor 1
SAMD9L sterile alpha motif domain containing 9-like
SAP130 Sin3A-associated protein, 130kDa
SCAMP5 secretory carrier membrane protein 5
SCARNA27 small Cajal body-specific RNA 27
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERPINA9 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
SGK223 homolog of rat pragma of Rnd2
SHB Src homology 2 domain containing adaptor protein B
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIX5 SIX homeobox 5
SLAMF6 SLAM family member 6
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC22A9 solute carrier family 22 (organic anion transporter), member 9
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1
SLC25A34 solute carrier family 25, member 34
SLC30A10 solute carrier family 30, member 10
SLC35G1 solute carrier family 35, member G1
SLC38A5 solute carrier family 38, member 5
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMIM21 small integral membrane protein 21
SNCB synuclein, beta
SNORA11E small nucleolar RNA, H/ACA box 11E
SNORA28 small nucleolar RNA, H/ACA box 28
SNORA54 small nucleolar RNA, H/ACA box 54
SNORA80E small nucleolar RNA, H/ACA box 80E
SNX25 sorting nexin 25
SNX8 sorting nexin 8
SOCS2 suppressor of cytokine signaling 2
SOST sclerostin
SOX30 SRY (sex determining region Y)-box 30
SP110 SP110 nuclear body protein
SP6 Sp6 transcription factor
SPACA3 sperm acrosome associated 3
SPC24 SPC24, NDC80 kinetochore complex component
SPRR2D small proline-rich protein 2D
SPRR2F small proline-rich protein 2F
SPTB spectrin, beta, erythrocytic
STAP1 signal transducing adaptor family member 1
STRADB STE20-related kinase adaptor beta
SYNPO synaptopodin
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCERG1L transcription elongation regulator 1-like
TCOF1 Treacher Collins-Franceschetti syndrome 1
TECTA tectorin alpha
TERT telomerase reverse transcriptase
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFF3 trefoil factor 3 (intestinal)
THPO thrombopoietin
TIMP4 TIMP metallopeptidase inhibitor 4
TMEM200A transmembrane protein 200A
TMEM244 transmembrane protein 244
TMOD1 tropomodulin 1
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TOPAZ1 testis and ovary specific PAZ domain containing 1
TOX3 TOX high mobility group box family member 3
TRAP1 TNF receptor-associated protein 1
TRIM61 tripartite motif containing 61
TSPAN17 tetraspanin 17
TSPAN5 tetraspanin 5
TYR tyrosinase
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UPK3B uroplakin 3B
USP18 ubiquitin specific peptidase 18
USP2 ubiquitin specific peptidase 2
USP53 ubiquitin specific peptidase 53
VARS2 valyl-tRNA synthetase 2, mitochondrial
WDFY4 WDFY family member 4
WNT2 wingless-type MMTV integration site family member 2
XAF1 XIAP associated factor 1
ZBP1 Z-DNA binding protein 1
ZBTB32 zinc finger and BTB domain containing 32
ZNF280A zinc finger protein 280A
ZNF532 zinc finger protein 532

low expression

Symbol Name
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
BLCAP bladder cancer associated protein
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32
EIF4A2 eukaryotic translation initiation factor 4A2
EXD2 exonuclease 3'-5' domain containing 2
L3MBTL1 l(3)mbt-like 1 (Drosophila)
PHF20 PHD finger protein 20
PROSER1 proline and serine rich 1
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic)
RNF114 ring finger protein 114
RPRD1B regulation of nuclear pre-mRNA domain containing 1B
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas)
RTCA RNA 3'-terminal phosphate cyclase
RTFDC1 replication termination factor 2 domain containing 1
SERINC3 serine incorporator 3
SMAD5 SMAD family member 5
SRSF6 serine/arginine-rich splicing factor 6
SYS1 Sys1 golgi trafficking protein
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
XRN2 5'-3' exoribonuclease 2
ZNF35 zinc finger protein 35
ZNF516 zinc finger protein 516
ZSWIM1 zinc finger, SWIM-type containing 1