Acute Myeloid Leukemia_LAML_TCGA-AB-2858-03A-01T-0736-13 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Acute Myeloid Leukemia_LAML (The Cancer Genome Atlas)
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376 genes with high or low expression in Acute Myeloid Leukemia_LAML_TCGA-AB-2858-03A-01T-0736-13 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTL10 actin-like 10
ACVR1B activin A receptor, type IB
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ADRA2B adrenoceptor alpha 2B
ADRA2C adrenoceptor alpha 2C
ADRM1 adhesion regulating molecule 1
AIRE autoimmune regulator
AKAP2 A kinase (PRKA) anchor protein 2
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ANKRD19P ankyrin repeat domain 19, pseudogene
ANKUB1 ankyrin repeat and ubiquitin domain containing 1
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP3M2 adaptor-related protein complex 3, mu 2 subunit
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
AQP6 aquaporin 6, kidney specific
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL11 ADP-ribosylation factor-like 11
ARPP21 cAMP-regulated phosphoprotein, 21kDa
ATG9B autophagy related 9B
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
BAG5 BCL2-associated athanogene 5
BAIAP3 BAI1-associated protein 3
BCL6B B-cell CLL/lymphoma 6, member B
BCL9 B-cell CLL/lymphoma 9
BSDC1 BSD domain containing 1
BTBD19 BTB (POZ) domain containing 19
BTN1A1 butyrophilin, subfamily 1, member A1
C10ORF35 chromosome 10 open reading frame 35
C12ORF42 chromosome 12 open reading frame 42
C1ORF110 chromosome 1 open reading frame 110
C1ORF186 chromosome 1 open reading frame 186
C1ORF94 chromosome 1 open reading frame 94
C2ORF54 chromosome 2 open reading frame 54
C2ORF66 chromosome 2 open reading frame 66
C6ORF58 chromosome 6 open reading frame 58
C7ORF49 chromosome 7 open reading frame 49
C7ORF61 chromosome 7 open reading frame 61
CA6 carbonic anhydrase VI
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CATSPER4 cation channel, sperm associated 4
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC154 coiled-coil domain containing 154
CD19 CD19 molecule
CD38 CD38 molecule
CD53 CD53 molecule
CD58 CD58 molecule
CD96 CD96 molecule
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CDK15 cyclin-dependent kinase 15
CDR2 cerebellar degeneration-related protein 2, 62kDa
CEACAM18 carcinoembryonic antigen-related cell adhesion molecule 18
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CEP41 centrosomal protein 41kDa
CEP85 centrosomal protein 85kDa
CERS3 ceramide synthase 3
CHCHD6 coiled-coil-helix-coiled-coil-helix domain containing 6
CLEC2L C-type lectin domain family 2, member L
CNOT8 CCR4-NOT transcription complex, subunit 8
CNST consortin, connexin sorting protein
COX8C cytochrome c oxidase subunit VIIIC
CPNE7 copine VII
CRBN cereblon
CREB3L4 cAMP responsive element binding protein 3-like 4
CRYAA crystallin, alpha A
CRYZ crystallin, zeta (quinone reductase)
CSRNP2 cysteine-serine-rich nuclear protein 2
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
CXORF56 chromosome X open reading frame 56
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1
DAGLB diacylglycerol lipase, beta
DEPTOR DEP domain containing MTOR-interacting protein
DKFZP434H168 uncharacterized LOC26077
DNAH8 dynein, axonemal, heavy chain 8
DNAJC14 DnaJ (Hsp40) homolog, subfamily C, member 14
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DOK3 docking protein 3
DPCR1 diffuse panbronchiolitis critical region 1
DPEP1 dipeptidase 1 (renal)
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EEF1A1P9 eukaryotic translation elongation factor 1 alpha 1 pseudogene 9
ELMO1 engulfment and cell motility 1
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7
EPCAM epithelial cell adhesion molecule
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
ERVFRD-1 endogenous retrovirus group FRD, member 1
ESAM endothelial cell adhesion molecule
ETHE1 ethylmalonic encephalopathy 1
EVPL envoplakin
F11R F11 receptor
FAM153A family with sequence similarity 153, member A
FAM180B family with sequence similarity 180, member B
FAM181A-AS1 FAM181A antisense RNA 1
FAM212A family with sequence similarity 212, member A
FAM216B family with sequence similarity 216, member B
FAM41C family with sequence similarity 41, member C
FAM69B family with sequence similarity 69, member B
FAS Fas cell surface death receptor
FBXL13 F-box and leucine-rich repeat protein 13
FBXW9 F-box and WD repeat domain containing 9
FOXL1 forkhead box L1
FUNDC1 FUN14 domain containing 1
FUOM fucose mutarotase
FXYD3 FXYD domain containing ion transport regulator 3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GBA3 glucosidase, beta, acid 3 (gene/pseudogene)
GDA guanine deaminase
GLB1L3 galactosidase, beta 1-like 3
GLRA3 glycine receptor, alpha 3
GLYATL1 glycine-N-acyltransferase-like 1
GNPDA1 glucosamine-6-phosphate deaminase 1
GOLGA2P5 golgin A2 pseudogene 5
GPA33 glycoprotein A33 (transmembrane)
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial
GPHA2 glycoprotein hormone alpha 2
GPM6B glycoprotein M6B
GPR142 G protein-coupled receptor 142
GPR152 G protein-coupled receptor 152
GPR32 G protein-coupled receptor 32
GPR45 G protein-coupled receptor 45
GPRC6A G protein-coupled receptor, class C, group 6, member A
GRAP GRB2-related adaptor protein
GRAPL GRB2-related adaptor protein-like
GREM1 gremlin 1, DAN family BMP antagonist
GRM3 glutamate receptor, metabotropic 3
GRPEL1 GrpE-like 1, mitochondrial (E. coli)
GSDMD gasdermin D
GSTM1 glutathione S-transferase mu 1
GUCA1C guanylate cyclase activator 1C
HAL histidine ammonia-lyase
HIST2H3D histone cluster 2, H3d
HMGN4 high mobility group nucleosomal binding domain 4
HPGDS hematopoietic prostaglandin D synthase
HSDL1 hydroxysteroid dehydrogenase like 1
HYAL2 hyaluronoglucosaminidase 2
HYAL3 hyaluronoglucosaminidase 3
IKZF2 IKAROS family zinc finger 2 (Helios)
IL5RA interleukin 5 receptor, alpha
INO80C INO80 complex subunit C
IPO11 importin 11
IRX6 iroquois homeobox 6
ITGB4 integrin, beta 4
ITPKA inositol-trisphosphate 3-kinase A
JAK3 Janus kinase 3
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDM4B lysine (K)-specific demethylase 4B
KIAA1324L KIAA1324-like
KIFAP3 kinesin-associated protein 3
KLF17 Kruppel-like factor 17
KLHDC7A kelch domain containing 7A
KLHL17 kelch-like family member 17
KLRG2 killer cell lectin-like receptor subfamily G, member 2
KRBA1 KRAB-A domain containing 1
KREMEN2 kringle containing transmembrane protein 2
KRT1 keratin 1, type II
KRTAP5-10 keratin associated protein 5-10
KRTAP5-11 keratin associated protein 5-11
LCMT1 leucine carboxyl methyltransferase 1
LEPROTL1 leptin receptor overlapping transcript-like 1
LIMS1 LIM and senescent cell antigen-like domains 1
LINC00189 long intergenic non-protein coding RNA 189
LINC00235 long intergenic non-protein coding RNA 235
LINC00238 long intergenic non-protein coding RNA 238
LOC100131496 uncharacterized LOC100131496
LOC100268168 uncharacterized LOC100268168
LOC100270746 uncharacterized LOC100270746
LOC441455 makorin ring finger protein 1 pseudogene
LOC654342 lymphocyte-specific protein 1 pseudogene
LOC728554 THO complex 3 pseudogene
LOC93622 Morf4 family associated protein 1-like 1 pseudogene
LOR loricrin
LPAR5 lysophosphatidic acid receptor 5
LPCAT2 lysophosphatidylcholine acyltransferase 2
LRRC29 leucine rich repeat containing 29
LRRC70 leucine rich repeat containing 70
LSMEM2 leucine-rich single-pass membrane protein 2
M1AP meiosis 1 associated protein
MAGEA2 melanoma antigen family A2
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP3K19 mitogen-activated protein kinase kinase kinase 19
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MED28 mediator complex subunit 28
MEOX1 mesenchyme homeobox 1
MFAP4 microfibrillar-associated protein 4
MFRP membrane frizzled-related protein
MGMT O-6-methylguanine-DNA methyltransferase
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MLXIP MLX interacting protein
MOG myelin oligodendrocyte glycoprotein
MRPL15 mitochondrial ribosomal protein L15
NARFL nuclear prelamin A recognition factor-like
NEFL neurofilament, light polypeptide
NHLRC4 NHL repeat containing 4
NLRP2 NLR family, pyrin domain containing 2
NLRP6 NLR family, pyrin domain containing 6
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NOX3 NADPH oxidase 3
NPHP4 nephronophthisis 4
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRCAM neuronal cell adhesion molecule
NT5C2 5'-nucleotidase, cytosolic II
NTN1 netrin 1
NTPCR nucleoside-triphosphatase, cancer-related
ODF1 outer dense fiber of sperm tails 1
OR10G3 olfactory receptor, family 10, subfamily G, member 3
OR11A1 olfactory receptor, family 11, subfamily A, member 1
OR13A1 olfactory receptor, family 13, subfamily A, member 1
OR1A2 olfactory receptor, family 1, subfamily A, member 2
OR2H1 olfactory receptor, family 2, subfamily H, member 1
OR3A1 olfactory receptor, family 3, subfamily A, member 1
OR3A2 olfactory receptor, family 3, subfamily A, member 2
OR3A4P olfactory receptor, family 3, subfamily A, member 4 pseudogene
OTX2 orthodenticle homeobox 2
PADI3 peptidyl arginine deiminase, type III
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PALM paralemmin
PCDHGA11 protocadherin gamma subfamily A, 11
PCDHGA5 protocadherin gamma subfamily A, 5
PCDHGA6 protocadherin gamma subfamily A, 6
PCDHGB2 protocadherin gamma subfamily B, 2
PCDHGB6 protocadherin gamma subfamily B, 6
PCDHGB7 protocadherin gamma subfamily B, 7
PCTP phosphatidylcholine transfer protein
PDCD7 programmed cell death 7
PDF peptide deformylase (mitochondrial)
PDGFRL platelet-derived growth factor receptor-like
PGAM5 phosphoglycerate mutase family member 5
PGLYRP4 peptidoglycan recognition protein 4
PGS1 phosphatidylglycerophosphate synthase 1
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCG1 phospholipase C, gamma 1
PLXNB3 plexin B3
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POM121L10P POM121 transmembrane nucleoporin-like 10, pseudogene
PON2 paraoxonase 2
POU4F1 POU class 4 homeobox 1
PPAP2A phosphatidic acid phosphatase type 2A
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRAP1 proline-rich acidic protein 1
PRCD progressive rod-cone degeneration
PRR35 proline rich 35
PRSS33 protease, serine, 33
PSG4 pregnancy specific beta-1-glycoprotein 4
PSG9 pregnancy specific beta-1-glycoprotein 9
PTGDR2 prostaglandin D2 receptor 2
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PTTG1IP pituitary tumor-transforming 1 interacting protein
PTX4 pentraxin 4, long
QARS glutaminyl-tRNA synthetase
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RASAL1 RAS protein activator like 1 (GAP1 like)
RCAN1 regulator of calcineurin 1
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RD3 retinal degeneration 3
RGS10 regulator of G-protein signaling 10
RIOK2 RIO kinase 2
RNF216P1 ring finger protein 216 pseudogene 1
RNF219 ring finger protein 219
RNF222 ring finger protein 222
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL31 ribosomal protein L31
RPS4X ribosomal protein S4, X-linked
RPS7 ribosomal protein S7
RRN3P3 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 3
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas)
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SAMD3 sterile alpha motif domain containing 3
SAP30L SAP30-like
SCCPDH saccharopine dehydrogenase (putative)
SDCCAG8 serologically defined colon cancer antigen 8
SEPT6 septin 6
SFXN4 sideroflexin 4
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIPA1L2 signal-induced proliferation-associated 1 like 2
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC2A7 solute carrier family 2 (facilitated glucose transporter), member 7
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC45A3 solute carrier family 45, member 3
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SLCO5A1 solute carrier organic anion transporter family, member 5A1
SNAP23 synaptosomal-associated protein, 23kDa
SORD sorbitol dehydrogenase
SPATA32 spermatogenesis associated 32
SPINK4 serine peptidase inhibitor, Kazal type 4
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STK38 serine/threonine kinase 38
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUMF1 sulfatase modifying factor 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SV2B synaptic vesicle glycoprotein 2B
SYNDIG1L synapse differentiation inducing 1-like
SYNGR1 synaptogyrin 1
TARBP2 TAR (HIV-1) RNA binding protein 2
TBC1D31 TBC1 domain family, member 31
TBX22 T-box 22
TCAP titin-cap
TCF3 transcription factor 3
TEF thyrotrophic embryonic factor
TEKT5 tektin 5
TELO2 telomere maintenance 2
THEM4 thioesterase superfamily member 4
TM7SF3 transmembrane 7 superfamily member 3
TMEM140 transmembrane protein 140
TMEM206 transmembrane protein 206
TMEM243 transmembrane protein 243, mitochondrial
TMEM43 transmembrane protein 43
TMEM44 transmembrane protein 44
TMEM88B transmembrane protein 88B
TMIE transmembrane inner ear
TP53TG3B TP53 target 3B
TPK1 thiamin pyrophosphokinase 1
TPO thyroid peroxidase
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRAF3IP2 TRAF3 interacting protein 2
TRAT1 T cell receptor associated transmembrane adaptor 1
TRIM48 tripartite motif containing 48
TRIM6 tripartite motif containing 6
TRIM64 tripartite motif containing 64
TRIO trio Rho guanine nucleotide exchange factor
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1
TSG1 tumor suppressor TSG1
TSGA13 testis specific, 13
TSKS testis-specific serine kinase substrate
TSPAN13 tetraspanin 13
TSPAN7 tetraspanin 7
TSSK1B testis-specific serine kinase 1B
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
TTLL9 tubulin tyrosine ligase-like family member 9
TUBB6 tubulin, beta 6 class V
TWSG1 twisted gastrulation BMP signaling modulator 1
UBFD1 ubiquitin family domain containing 1
UGP2 UDP-glucose pyrophosphorylase 2
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
UNC119B unc-119 homolog B (C. elegans)
UNC5D unc-5 homolog D (C. elegans)
UOX urate oxidase, pseudogene
UROC1 urocanate hydratase 1
USP10 ubiquitin specific peptidase 10
USP26 ubiquitin specific peptidase 26
VAMP5 vesicle-associated membrane protein 5
VLDLR very low density lipoprotein receptor
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae)
VWA9 von Willebrand factor A domain containing 9
XRN2 5'-3' exoribonuclease 2
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZACN zinc activated ligand-gated ion channel
ZBTB42 zinc finger and BTB domain containing 42
ZBTB9 zinc finger and BTB domain containing 9
ZFP57 ZFP57 zinc finger protein
ZHX2 zinc fingers and homeoboxes 2
ZNF440 zinc finger protein 440
ZNF576 zinc finger protein 576
ZNF70 zinc finger protein 70
ZNF804A zinc finger protein 804A

low expression

Symbol Name
OGG1 8-oxoguanine DNA glycosylase
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1