Acute Myeloid Leukemia_LAML_TCGA-AB-2900-03A-01T-0735-13 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Acute Myeloid Leukemia_LAML (The Cancer Genome Atlas)
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284 genes with high or low expression in Acute Myeloid Leukemia_LAML_TCGA-AB-2900-03A-01T-0735-13 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AANAT aralkylamine N-acetyltransferase
ABHD6 abhydrolase domain containing 6
ABLIM3 actin binding LIM protein family, member 3
ACOT1 acyl-CoA thioesterase 1
ACSM4 acyl-CoA synthetase medium-chain family member 4
ADAM17 ADAM metallopeptidase domain 17
ADAMDEC1 ADAM-like, decysin 1
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADGRE5 adhesion G protein-coupled receptor E5
ADGRG4 adhesion G protein-coupled receptor G4
ADGRV1 adhesion G protein-coupled receptor V1
ADORA3 adenosine A3 receptor
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALOX5 arachidonate 5-lipoxygenase
ANKRD34C ankyrin repeat domain 34C
ANO8 anoctamin 8
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOC4 apolipoprotein C-IV
ARGFXP2 arginine-fifty homeobox pseudogene 2
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19
ARL14 ADP-ribosylation factor-like 14
ARMC12 armadillo repeat containing 12
ARRDC3 arrestin domain containing 3
ARSF arylsulfatase F
ASB2 ankyrin repeat and SOCS box containing 2
ASCC1 activating signal cointegrator 1 complex subunit 1
ASL argininosuccinate lyase
ATP11AUN ATP11A upstream neighbor
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
BEAN1 brain expressed, associated with NEDD4, 1
BLM Bloom syndrome, RecQ helicase-like
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
C10ORF54 chromosome 10 open reading frame 54
C10ORF76 chromosome 10 open reading frame 76
C10ORF91 chromosome 10 open reading frame 91
C16ORF45 chromosome 16 open reading frame 45
C17ORF53 chromosome 17 open reading frame 53
C19ORF35 chromosome 19 open reading frame 35
C20ORF194 chromosome 20 open reading frame 194
C3ORF62 chromosome 3 open reading frame 62
C4ORF22 chromosome 4 open reading frame 22
C4ORF36 chromosome 4 open reading frame 36
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4
CAMTA2 calmodulin binding transcription activator 2
CCDC150 coiled-coil domain containing 150
CCDC88B coiled-coil domain containing 88B
CD163 CD163 molecule
CD163L1 CD163 molecule-like 1
CD53 CD53 molecule
CDK11B cyclin-dependent kinase 11B
CELF2 CUGBP, Elav-like family member 2
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CHKA choline kinase alpha
CLASP1 cytoplasmic linker associated protein 1
COL28A1 collagen, type XXVIII, alpha 1
CPNE8 copine VIII
CREG1 cellular repressor of E1A-stimulated genes 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRTAP cartilage associated protein
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CT45A1 cancer/testis antigen family 45, member A1
CT45A3 cancer/testis antigen family 45, member A3
CTSB cathepsin B
CTTNBP2NL CTTNBP2 N-terminal like
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DAAM2 dishevelled associated activator of morphogenesis 2
DFNA5 deafness, autosomal dominant 5
DKK2 dickkopf WNT signaling pathway inhibitor 2
DKK4 dickkopf WNT signaling pathway inhibitor 4
DNASE1L1 deoxyribonuclease I-like 1
DUSP12 dual specificity phosphatase 12
EBI3 Epstein-Barr virus induced 3
EPO erythropoietin
EPS8L3 EPS8-like 3
EVA1C eva-1 homolog C (C. elegans)
EXOC3 exocyst complex component 3
F12 coagulation factor XII (Hageman factor)
FAM179A family with sequence similarity 179, member A
FAM21A family with sequence similarity 21, member A
FAM21C family with sequence similarity 21, member C
FAM26D family with sequence similarity 26, member D
FAM53B family with sequence similarity 53, member B
FAM65B family with sequence similarity 65, member B
FASTKD5 FAST kinase domains 5
FCHO2 FCH domain only 2
FKBP5 FK506 binding protein 5
FMR1NB fragile X mental retardation 1 neighbor
FN1 fibronectin 1
FOXO3 forkhead box O3
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FUCA2 fucosidase, alpha-L- 2, plasma
G6PD glucose-6-phosphate dehydrogenase
GAL3ST2 galactose-3-O-sulfotransferase 2
GAS7 growth arrest-specific 7
GCLC glutamate-cysteine ligase, catalytic subunit
GGNBP2 gametogenetin binding protein 2
GGT1 gamma-glutamyltransferase 1
GGT3P gamma-glutamyltransferase 3 pseudogene
GGTLC1 gamma-glutamyltransferase light chain 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPR34 G protein-coupled receptor 34
GSN gelsolin
GSR glutathione reductase
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
H3F3C H3 histone, family 3C
HAPLN3 hyaluronan and proteoglycan link protein 3
HCLS1 hematopoietic cell-specific Lyn substrate 1
HECTD2 HECT domain containing E3 ubiquitin protein ligase 2
HIPK2 homeodomain interacting protein kinase 2
HIST1H2BO histone cluster 1, H2bo
HIST1H4G histone cluster 1, H4g
HIST1H4I histone cluster 1, H4i
HMGB2 high mobility group box 2
HMGN4 high mobility group nucleosomal binding domain 4
HSBP1L1 heat shock factor binding protein 1-like 1
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
IGSF10 immunoglobulin superfamily, member 10
IL18 interleukin 18
IL1R2 interleukin 1 receptor, type II
INS-IGF2 INS-IGF2 readthrough
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB5 integrin, beta 5
ITPKC inositol-trisphosphate 3-kinase C
JDP2 Jun dimerization protein 2
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KDF1 keratinocyte differentiation factor 1
KLF10 Kruppel-like factor 10
KLF13 Kruppel-like factor 13
KRTAP10-4 keratin associated protein 10-4
LDHB lactate dehydrogenase B
LDHD lactate dehydrogenase D
LDLRAD3 low density lipoprotein receptor class A domain containing 3
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LINC00174 long intergenic non-protein coding RNA 174
LMBR1 limb development membrane protein 1
LOC100130872 uncharacterized LOC100130872
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC284379 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 pseudogene
LOC285847 uncharacterized LOC285847
LOC650293 seven transmembrane helix receptor
LOR loricrin
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
LYZL6 lysozyme-like 6
MAOA monoamine oxidase A
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2
MAP2K1 mitogen-activated protein kinase kinase 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MBD6 methyl-CpG binding domain protein 6
MERTK MER proto-oncogene, tyrosine kinase
METTL7A methyltransferase like 7A
MFGE8 milk fat globule-EGF factor 8 protein
MFSD1 major facilitator superfamily domain containing 1
MGAM maltase-glucoamylase
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MKNK1 MAP kinase interacting serine/threonine kinase 1
MMP19 matrix metallopeptidase 19
MMP7 matrix metallopeptidase 7
MRVI1 murine retrovirus integration site 1 homolog
MYBPC1 myosin binding protein C, slow type
MYRIP myosin VIIA and Rab interacting protein
NCOR2 nuclear receptor corepressor 2
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NFIL3 nuclear factor, interleukin 3 regulated
NHSL1 NHS-like 1
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NPEPL1 aminopeptidase-like 1
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16
OLAH oleoyl-ACP hydrolase
OR2V2 olfactory receptor, family 2, subfamily V, member 2
ORMDL1 ORMDL sphingolipid biosynthesis regulator 1
PCTP phosphatidylcholine transfer protein
PDE1B phosphodiesterase 1B, calmodulin-dependent
PER1 period circadian clock 1
PHC2 polyhomeotic homolog 2 (Drosophila)
PICK1 protein interacting with PRKCA 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKP2 plakophilin 2
PLA2G15 phospholipase A2, group XV
PLEC plectin
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3
POTEE POTE ankyrin domain family, member E
PPM1M protein phosphatase, Mg2+/Mn2+ dependent, 1M
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRM2 protamine 2
PRR18 proline rich 18
PSD4 pleckstrin and Sec7 domain containing 4
PTK2B protein tyrosine kinase 2 beta
PTK6 protein tyrosine kinase 6
RAB17 RAB17, member RAS oncogene family
RBMS3 RNA binding motif, single stranded interacting protein 3
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RINL Ras and Rab interactor-like
RLN3 relaxin 3
RPN1 ribophorin I
S100A5 S100 calcium binding protein A5
SAP30 Sin3A-associated protein, 30kDa
SAT1 spermidine/spermine N1-acetyltransferase 1
SCIN scinderin
SCRG1 stimulator of chondrogenesis 1
SDC4 syndecan 4
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae)
SEPW1 selenoprotein W, 1
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)
SESN1 sestrin 1
SGMS2 sphingomyelin synthase 2
SH2D4A SH2 domain containing 4A
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SHROOM2 shroom family member 2
SIGLEC11 sialic acid binding Ig-like lectin 11
SIGLEC16 sialic acid binding Ig-like lectin 16 (gene/pseudogene)
SIRT5 sirtuin 5
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMAP2 small ArfGAP2
SMIM3 small integral membrane protein 3
SMPX small muscle protein, X-linked
SNAP29 synaptosomal-associated protein, 29kDa
SNORA72 small nucleolar RNA, H/ACA box 72
SORCS2 sortilin-related VPS10 domain containing receptor 2
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPRY4 sprouty homolog 4 (Drosophila)
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SQRDL sulfide quinone reductase-like (yeast)
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SUMF1 sulfatase modifying factor 1
SYS1 Sys1 golgi trafficking protein
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TBCC tubulin folding cofactor C
TBXAS1 thromboxane A synthase 1 (platelet)
TCN2 transcobalamin II
TIMP4 TIMP metallopeptidase inhibitor 4
TK2 thymidine kinase 2, mitochondrial
TMEM236 transmembrane protein 236
TMOD1 tropomodulin 1
TNFSF12-TNFSF13 TNFSF12-TNFSF13 readthrough
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TPD52L2 tumor protein D52-like 2
TPST1 tyrosylprotein sulfotransferase 1
TRIM50 tripartite motif containing 50
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TSC22D3 TSC22 domain family, member 3
TTC38 tetratricopeptide repeat domain 38
TWF2 twinfilin actin binding protein 2
TXNIP thioredoxin interacting protein
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UFD1L ubiquitin fusion degradation 1 like (yeast)
UPK3BL uroplakin 3B-like
UPP1 uridine phosphorylase 1
USP15 ubiquitin specific peptidase 15
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
VENTX VENT homeobox
VIM vimentin
VSIG4 V-set and immunoglobulin domain containing 4
VSTM2L V-set and transmembrane domain containing 2 like
WASF2 WAS protein family, member 2
WBP11P1 WW domain binding protein 11 pseudogene 1
WDR81 WD repeat domain 81
ZBTB16 zinc finger and BTB domain containing 16
ZBTB43 zinc finger and BTB domain containing 43
ZC3H7A zinc finger CCCH-type containing 7A
ZCCHC2 zinc finger, CCHC domain containing 2
ZNF317 zinc finger protein 317

low expression

Symbol Name
ASTE1 asteroid homolog 1 (Drosophila)
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
DHRS4-AS1 DHRS4 antisense RNA 1
ERGIC2 ERGIC and golgi 2
EXOSC3 exosome component 3
PPP1R10 protein phosphatase 1, regulatory subunit 10
RBM12 RNA binding motif protein 12
SMC1A structural maintenance of chromosomes 1A