Acute Myeloid Leukemia_LAML_TCGA-AB-2915-03A-01T-0740-13 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Acute Myeloid Leukemia_LAML (The Cancer Genome Atlas)
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277 genes with high or low expression in Acute Myeloid Leukemia_LAML_TCGA-AB-2915-03A-01T-0740-13 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABTB1 ankyrin repeat and BTB (POZ) domain containing 1
ADIPOR1 adiponectin receptor 1
ADM adrenomedullin
ADRB3 adrenoceptor beta 3
ALPK2 alpha-kinase 2
ALPL alkaline phosphatase, liver/bone/kidney
ARF1 ADP-ribosylation factor 1
ARHGAP9 Rho GTPase activating protein 9
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARRDC2 arrestin domain containing 2
ATG9A autophagy related 9A
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
B3GAT1 beta-1,3-glucuronyltransferase 1
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
BBC3 BCL2 binding component 3
BCL9 B-cell CLL/lymphoma 9
BEX2 brain expressed X-linked 2
BMP6 bone morphogenetic protein 6
BPIFC BPI fold containing family C
BTNL8 butyrophilin-like 8
C11ORF52 chromosome 11 open reading frame 52
C12ORF60 chromosome 12 open reading frame 60
C1ORF116 chromosome 1 open reading frame 116
C1ORF185 chromosome 1 open reading frame 185
C1ORF74 chromosome 1 open reading frame 74
C4ORF32 chromosome 4 open reading frame 32
C6ORF15 chromosome 6 open reading frame 15
C6ORF222 chromosome 6 open reading frame 222
CA4 carbonic anhydrase IV
CASS4 Cas scaffolding protein family member 4
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CD46 CD46 molecule, complement regulatory protein
CD8A CD8a molecule
CD8B CD8b molecule
CDCP1 CUB domain containing protein 1
CFI complement factor I
CH25H cholesterol 25-hydroxylase
CHIT1 chitinase 1 (chitotriosidase)
CISH cytokine inducible SH2-containing protein
CKB creatine kinase, brain
CLEC18A C-type lectin domain family 18, member A
CLIC2 chloride intracellular channel 2
CLRN1 clarin 1
CMTM2 CKLF-like MARVEL transmembrane domain containing 2
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8
CPEB4 cytoplasmic polyadenylation element binding protein 4
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CREB3L1 cAMP responsive element binding protein 3-like 1
CREB5 cAMP responsive element binding protein 5
CRISP2 cysteine-rich secretory protein 2
CTXN2 cortexin 2
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
CYYR1 cysteine/tyrosine-rich 1
DAPK2 death-associated protein kinase 2
DDO D-aspartate oxidase
DEFB125 defensin, beta 125
DGAT2 diacylglycerol O-acyltransferase 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DSPP dentin sialophosphoprotein
DUSP13 dual specificity phosphatase 13
DUSP3 dual specificity phosphatase 3
DYTN dystrotelin
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EOMES eomesodermin
EPHB2 EPH receptor B2
EPS8 epidermal growth factor receptor pathway substrate 8
EXT1 exostosin glycosyltransferase 1
FAM169A family with sequence similarity 169, member A
FAM214B family with sequence similarity 214, member B
FAM219B family with sequence similarity 219, member B
FAM222B family with sequence similarity 222, member B
FAM58BP cyclin-related protein FAM58B
FAR2 fatty acyl CoA reductase 2
FBXO30 F-box protein 30
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCRL6 Fc receptor-like 6
FFAR2 free fatty acid receptor 2
FFAR3 free fatty acid receptor 3
FGFR4 fibroblast growth factor receptor 4
FHDC1 FH2 domain containing 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GDF15 growth differentiation factor 15
GIPC2 GIPC PDZ domain containing family, member 2
GJC2 gap junction protein, gamma 2, 47kDa
GLB1L galactosidase, beta 1-like
GLI2 GLI family zinc finger 2
GLIPR1 GLI pathogenesis-related 1
GLUL glutamate-ammonia ligase
GNG8 guanine nucleotide binding protein (G protein), gamma 8
GPA33 glycoprotein A33 (transmembrane)
GRID1 glutamate receptor, ionotropic, delta 1
GSN gelsolin
GUCY1B3 guanylate cyclase 1, soluble, beta 3
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
HABP2 hyaluronan binding protein 2
HAS2-AS1 HAS2 antisense RNA 1
HBA2 hemoglobin, alpha 2
HBE1 hemoglobin, epsilon 1
HBG1 hemoglobin, gamma A
HBG2 hemoglobin, gamma G
HGC6.3 uncharacterized LOC100128124
HMP19 HMP19 protein
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IFITM2 interferon induced transmembrane protein 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL36B interleukin 36, beta
IL36G interleukin 36, gamma
IL36RN interleukin 36 receptor antagonist
IPO9 importin 9
ITLN1 intelectin 1 (galactofuranose binding)
ITLN2 intelectin 2
JAKMIP1 janus kinase and microtubule interacting protein 1
JUNB jun B proto-oncogene
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KITLG KIT ligand
KLHDC8A kelch domain containing 8A
KRTAP10-10 keratin associated protein 10-10
KRTAP10-4 keratin associated protein 10-4
KRTAP10-9 keratin associated protein 10-9
KRTAP5-2 keratin associated protein 5-2
LEFTY1 left-right determination factor 1
LGALS8 lectin, galactoside-binding, soluble, 8
LHFPL1 lipoma HMGIC fusion partner-like 1
LIMK2 LIM domain kinase 2
LINC00518 long intergenic non-protein coding RNA 518
LOC100192426 uncharacterized LOC100192426
LOC284788 uncharacterized LOC284788
LOC286359 uncharacterized LOC286359
LPGAT1 lysophosphatidylglycerol acyltransferase 1
LPIN2 lipin 2
LYPD4 LY6/PLAUR domain containing 4
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MMP25 matrix metallopeptidase 25
MOGAT3 monoacylglycerol O-acyltransferase 3
MPP1 membrane protein, palmitoylated 1, 55kDa
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
NATD1 N-acetyltransferase domain containing 1
NECAB2 N-terminal EF-hand calcium binding protein 2
NHLH1 nescient helix loop helix 1
NLRP2 NLR family, pyrin domain containing 2
NPBWR1 neuropeptides B/W receptor 1
NSUN3 NOP2/Sun domain family, member 3
NUAK2 NUAK family, SNF1-like kinase, 2
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
OR2L13 olfactory receptor, family 2, subfamily L, member 13
OR2L1P olfactory receptor, family 2, subfamily L, member 1 pseudogene
OR2T33 olfactory receptor, family 2, subfamily T, member 33
OR2T8 olfactory receptor, family 2, subfamily T, member 8
OR2W3 olfactory receptor, family 2, subfamily W, member 3
OR4D2 olfactory receptor, family 4, subfamily D, member 2
OR52N4 olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene)
OR56B1 olfactory receptor, family 56, subfamily B, member 1
OR6K2 olfactory receptor, family 6, subfamily K, member 2
OR6K3 olfactory receptor, family 6, subfamily K, member 3
OR8G5 olfactory receptor, family 8, subfamily G, member 5
PABPC5 poly(A) binding protein, cytoplasmic 5
PAGE2B P antigen family, member 2B
PARP1 poly (ADP-ribose) polymerase 1
PAX9 paired box 9
PCDH11X protocadherin 11 X-linked
PCDHB15 protocadherin beta 15
PEX6 peroxisomal biogenesis factor 6
PGLYRP3 peptidoglycan recognition protein 3
PGLYRP4 peptidoglycan recognition protein 4
PKD2L1 polycystic kidney disease 2-like 1
PPY2P pancreatic polypeptide 2, pseudogene
PRG1 p53-responsive gene 1
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PYCR2 pyrroline-5-carboxylate reductase family, member 2
QPCT glutaminyl-peptide cyclotransferase
R3HDM4 R3H domain containing 4
RAB4A RAB4A, member RAS oncogene family
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RASEF RAS and EF-hand domain containing
RBBP5 retinoblastoma binding protein 5
REM2 RAS (RAD and GEM)-like GTP binding 2
RGS2 regulator of G-protein signaling 2
RNF145 ring finger protein 145
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RUFY1 RUN and FYVE domain containing 1
SEC14L1 SEC14-like 1 (S. cerevisiae)
SH3BP5L SH3-binding domain protein 5-like
SIAH2 siah E3 ubiquitin protein ligase 2
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC16A6 solute carrier family 16, member 6
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC25A44 solute carrier family 25, member 44
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SNHG10 small nucleolar RNA host gene 10
SOCS3 suppressor of cytokine signaling 3
SORCS1 sortilin-related VPS10 domain containing receptor 1
SPACA3 sperm acrosome associated 3
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
STEAP4 STEAP family member 4
SYS1-DBNDD2 SYS1-DBNDD2 readthrough (NMD candidate)
TBC1D3H TBC1 domain family, member 3H
TBCE tubulin folding cofactor E
TCEANC transcription elongation factor A (SII) N-terminal and central domain containing
TJP2 tight junction protein 2
TM4SF1 transmembrane 4 L six family member 1
TMCC2 transmembrane and coiled-coil domain family 2
TPH2 tryptophan hydroxylase 2
TRIM58 tripartite motif containing 58
TSSK1B testis-specific serine kinase 1B
TTLL7 tubulin tyrosine ligase-like family member 7
TTYH2 tweety family member 2
TUBG2 tubulin, gamma 2
UBA7 ubiquitin-like modifier activating enzyme 7
UBE2O ubiquitin-conjugating enzyme E2O
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VNN1 vanin 1
VNN3 vanin 3
WDR26 WD repeat domain 26
WDR72 WD repeat domain 72
WNT9B wingless-type MMTV integration site family, member 9B
WWC3 WWC family member 3
XCR1 chemokine (C motif) receptor 1
XPO7 exportin 7
XPR1 xenotropic and polytropic retrovirus receptor 1
XXYLT1 xyloside xylosyltransferase 1
ZBTB34 zinc finger and BTB domain containing 34
ZC3H11A zinc finger CCCH-type containing 11A
ZFPM2 zinc finger protein, FOG family member 2
ZNF185 zinc finger protein 185 (LIM domain)
ZNF23 zinc finger protein 23
ZNF672 zinc finger protein 672

low expression

Symbol Name
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARMC10 armadillo repeat containing 10
CEP250 centrosomal protein 250kDa
CPNE1 copine I
CUX1 cut-like homeobox 1
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
FAM35A family with sequence similarity 35, member A
FAM35BP family with sequence similarity 35, member A pseudogene
FBXO25 F-box protein 25
GATAD1 GATA zinc finger domain containing 1
GLUD1 glutamate dehydrogenase 1
IFT52 intraflagellar transport 52
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LUC7L2 LUC7-like 2 (S. cerevisiae)
NCOA6 nuclear receptor coactivator 6
NNAT neuronatin
NOM1 nucleolar protein with MIF4G domain 1
PDAP1 PDGFA associated protein 1
PMPCB peptidase (mitochondrial processing) beta
PMS2P1 postmeiotic segregation increased 2 pseudogene 1
RNF114 ring finger protein 114
RPRD1B regulation of nuclear pre-mRNA domain containing 1B
SND1 staphylococcal nuclease and tudor domain containing 1
SRSF6 serine/arginine-rich splicing factor 6
STAU1 staufen double-stranded RNA binding protein 1
SYS1 Sys1 golgi trafficking protein
TOMM34 translocase of outer mitochondrial membrane 34
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TTI1 TELO2 interacting protein 1
UBE3C ubiquitin protein ligase E3C
WAPAL wings apart-like homolog (Drosophila)
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF3 zinc finger protein 3
ZNF789 zinc finger protein 789