Acute Myeloid Leukemia_LAML_TCGA-AB-2931-03A-01T-0740-13 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Acute Myeloid Leukemia_LAML (The Cancer Genome Atlas)
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416 genes with high or low expression in Acute Myeloid Leukemia_LAML_TCGA-AB-2931-03A-01T-0740-13 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACAD10 acyl-CoA dehydrogenase family, member 10
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACLY ATP citrate lyase
ACTN4 actinin, alpha 4
ACVR1 activin A receptor, type I
ADA adenosine deaminase
ADCY2 adenylate cyclase 2 (brain)
ADD1 adducin 1 (alpha)
ADGRB1 adhesion G protein-coupled receptor B1
ADGRE5 adhesion G protein-coupled receptor E5
ADHFE1 alcohol dehydrogenase, iron containing, 1
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AMACR alpha-methylacyl-CoA racemase
ANGPT2 angiopoietin 2
ANKRD37 ankyrin repeat domain 37
ANXA7 annexin A7
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
APOL4 apolipoprotein L, 4
AQP3 aquaporin 3 (Gill blood group)
AQP7P1 aquaporin 7 pseudogene 1
AQP7P3 aquaporin 7 pseudogene 3
ARHGAP22 Rho GTPase activating protein 22
ARRDC4 arrestin domain containing 4
ASIC5 acid sensing (proton gated) ion channel family member 5
ATG10 autophagy related 10
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP6V1G3 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
BEX4 brain expressed, X-linked 4
BGLAP bone gamma-carboxyglutamate (gla) protein
BTBD3 BTB (POZ) domain containing 3
C10ORF128 chromosome 10 open reading frame 128
C11ORF71 chromosome 11 open reading frame 71
C16ORF89 chromosome 16 open reading frame 89
C19ORF26 chromosome 19 open reading frame 26
C1ORF158 chromosome 1 open reading frame 158
C2CD4B C2 calcium-dependent domain containing 4B
C2ORF70 chromosome 2 open reading frame 70
C3ORF18 chromosome 3 open reading frame 18
C7ORF65 chromosome 7 open reading frame 65
C8ORF46 chromosome 8 open reading frame 46
CA5A carbonic anhydrase VA, mitochondrial
CABIN1 calcineurin binding protein 1
CALCRL calcitonin receptor-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBLN2 cerebellin 2 precursor
CCDC157 coiled-coil domain containing 157
CCDC185 coiled-coil domain containing 185
CCDC24 coiled-coil domain containing 24
CCDC38 coiled-coil domain containing 38
CCDC40 coiled-coil domain containing 40
CCDC6 coiled-coil domain containing 6
CCL1 chemokine (C-C motif) ligand 1
CCNL2 cyclin L2
CD47 CD47 molecule
CD80 CD80 molecule
CD99 CD99 molecule
CDRT15P1 CMT1A duplicated region transcript 15 pseudogene 1
CELA2A chymotrypsin-like elastase family, member 2A
CELA2B chymotrypsin-like elastase family, member 2B
CEP70 centrosomal protein 70kDa
CEP89 centrosomal protein 89kDa
CFAP20 cilia and flagella associated protein 20
CFAP69 cilia and flagella associated protein 69
CFH complement factor H
CHGB chromogranin B
CHKB choline kinase beta
CHODL chondrolectin
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
CIRBP cold inducible RNA binding protein
CISH cytokine inducible SH2-containing protein
CLCA3P chloride channel accessory 3, pseudogene
CLCA4 chloride channel accessory 4
CLEC3B C-type lectin domain family 3, member B
CNST consortin, connexin sorting protein
COL9A3 collagen, type IX, alpha 3
COMMD7 COMM domain containing 7
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRIP2 cysteine-rich protein 2
CSAD cysteine sulfinic acid decarboxylase
CTNS cystinosin, lysosomal cystine transporter
CTSC cathepsin C
CTXN1 cortexin 1
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
DAPK1 death-associated protein kinase 1
DBIL5P diazepam binding inhibitor-like 5, pseudogene
DBN1 drebrin 1
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEGS2 delta(4)-desaturase, sphingolipid 2
DENND6B DENN/MADD domain containing 6B
DIDO1 death inducer-obliterator 1
DNAH2 dynein, axonemal, heavy chain 2
DNM1P35 dynamin 1 pseudogene 35
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOCK1 dedicator of cytokinesis 1
DOCK3 dedicator of cytokinesis 3
DRC1 dynein regulatory complex subunit 1
DRC7 dynein regulatory complex subunit 7
DSCR3 Down syndrome critical region 3
DSCR9 Down syndrome critical region 9 (non-protein coding)
DTD1 D-tyrosyl-tRNA deacylase 1
DUSP18 dual specificity phosphatase 18
E2F5 E2F transcription factor 5, p130-binding
EFHB EF-hand domain family, member B
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF1B eukaryotic translation initiation factor 1B
ELAC1 elaC ribonuclease Z 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
ESYT3 extended synaptotagmin-like protein 3
FADS2 fatty acid desaturase 2
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAHD2B fumarylacetoacetate hydrolase domain containing 2B
FAIM Fas apoptotic inhibitory molecule
FAM169B family with sequence similarity 169, member B
FAM170B family with sequence similarity 170, member B
FAM173B family with sequence similarity 173, member B
FAM174B family with sequence similarity 174, member B
FAM179A family with sequence similarity 179, member A
FAM219B family with sequence similarity 219, member B
FAM224B family with sequence similarity 224, member B (non-protein coding)
FAM63A family with sequence similarity 63, member A
FAM83A family with sequence similarity 83, member A
FAM86B1 family with sequence similarity 86, member B1
FANCF Fanconi anemia, complementation group F
FAR2 fatty acyl CoA reductase 2
FAT1 FAT atypical cadherin 1
FBF1 Fas (TNFRSF6) binding factor 1
FBLN2 fibulin 2
FBXL2 F-box and leucine-rich repeat protein 2
FBXO34 F-box protein 34
FERD3L Fer3-like bHLH transcription factor
FEV FEV (ETS oncogene family)
FGF10 fibroblast growth factor 10
FGGY FGGY carbohydrate kinase domain containing
FHAD1 forkhead-associated (FHA) phosphopeptide binding domain 1
FMR1NB fragile X mental retardation 1 neighbor
FOXD4L5 forkhead box D4-like 5
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GALNT4 polypeptide N-acetylgalactosaminyltransferase 4
GDF3 growth differentiation factor 3
GGT5 gamma-glutamyltransferase 5
GLP1R glucagon-like peptide 1 receptor
GOLGA8B golgin A8 family, member B
GPR146 G protein-coupled receptor 146
GRB10 growth factor receptor-bound protein 10
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRK4 G protein-coupled receptor kinase 4
GTF2I general transcription factor IIi
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HARS2 histidyl-tRNA synthetase 2, mitochondrial
HDC histidine decarboxylase
HEATR5B HEAT repeat containing 5B
HERPUD2 HERPUD family member 2
HLX H2.0-like homeobox
HOMEZ homeobox and leucine zipper encoding
HOXA11 homeobox A11
HOXA11-AS HOXA11 antisense RNA
HOXB3 homeobox B3
HOXB4 homeobox B4
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDS iduronate 2-sulfatase
IFT43 intraflagellar transport 43
IFT81 intraflagellar transport 81
IFT88 intraflagellar transport 88
IL1R1 interleukin 1 receptor, type I
IMPG2 interphotoreceptor matrix proteoglycan 2
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1
INF2 inverted formin, FH2 and WH2 domain containing
INGX inhibitor of growth family, X-linked, pseudogene
IQCH IQ motif containing H
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB8 integrin, beta 8
JAG1 jagged 1
JMJD4 jumonji domain containing 4
KCTD3 potassium channel tetramerization domain containing 3
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0125 KIAA0125
KIAA1191 KIAA1191
KIF2B kinesin family member 2B
KITLG KIT ligand
KLHDC2 kelch domain containing 2
KLHDC9 kelch domain containing 9
KLHL4 kelch-like family member 4
KRBA2 KRAB-A domain containing 2
LAPTM4B lysosomal protein transmembrane 4 beta
LCN8 lipocalin 8
LCT lactase
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LGALS7B lectin, galactoside-binding, soluble, 7B
LIG3 ligase III, DNA, ATP-dependent
LINC00032 long intergenic non-protein coding RNA 32
LINC00202-1 long intergenic non-protein coding RNA 202-1
LINC00467 long intergenic non-protein coding RNA 467
LINC01553 long intergenic non-protein coding RNA 1553
LINGO4 leucine rich repeat and Ig domain containing 4
LOC100130093 uncharacterized LOC100130093
LOC153684 uncharacterized LOC153684
LOC344967 acyl-CoA thioesterase 7 pseudogene
LOH12CR1 loss of heterozygosity, 12, chromosomal region 1
LPIN1 lipin 1
LYRM1 LYR motif containing 1
LYRM9 LYR motif containing 9
LZTS2 leucine zipper, putative tumor suppressor 2
MAATS1 MYCBP-associated, testis expressed 1
MACC1 metastasis associated in colon cancer 1
MAEA macrophage erythroblast attacher
MAGED1 melanoma antigen family D1
MAP7 microtubule-associated protein 7
MAPKBP1 mitogen-activated protein kinase binding protein 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MATN2 matrilin 2
MED7 mediator complex subunit 7
MGC27382 uncharacterized MGC27382
MIPEP mitochondrial intermediate peptidase
MKRN3 makorin ring finger protein 3
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MPI mannose phosphate isomerase
MPZL2 myelin protein zero-like 2
MPZL3 myelin protein zero-like 3
MSMP microseminoprotein, prostate associated
MTHFSD methenyltetrahydrofolate synthetase domain containing
MYL9 myosin, light chain 9, regulatory
MYO1B myosin IB
NABP1 nucleic acid binding protein 1
NDFIP1 Nedd4 family interacting protein 1
NEK11 NIMA-related kinase 11
NET1 neuroepithelial cell transforming 1
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NLK nemo-like kinase
NPB neuropeptide B
NPTX2 neuronal pentraxin II
NQO1 NAD(P)H dehydrogenase, quinone 1
NRBP2 nuclear receptor binding protein 2
NT5C1B 5'-nucleotidase, cytosolic IB
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
OPRL1 opiate receptor-like 1
OR2T33 olfactory receptor, family 2, subfamily T, member 33
OR2V2 olfactory receptor, family 2, subfamily V, member 2
ORAI1 ORAI calcium release-activated calcium modulator 1
OSBPL3 oxysterol binding protein-like 3
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
P4HA3 prolyl 4-hydroxylase, alpha polypeptide III
PANK1 pantothenate kinase 1
PDE9A phosphodiesterase 9A
PDGFD platelet derived growth factor D
PFKP phosphofructokinase, platelet
PGBD1 piggyBac transposable element derived 1
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIFO primary cilia formation
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PITRM1 pitrilysin metallopeptidase 1
PKNOX1 PBX/knotted 1 homeobox 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLK5 polo-like kinase 5
PLS1 plastin 1
PLSCR2 phospholipid scramblase 2
PLXNA3 plexin A3
PMCH pro-melanin-concentrating hormone
PNMA1 paraneoplastic Ma antigen 1
PNPLA6 patatin-like phospholipase domain containing 6
PODNL1 podocan-like 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPY2P pancreatic polypeptide 2, pseudogene
PRIMPOL primase and polymerase (DNA-directed)
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPDC1 protein tyrosine phosphatase domain containing 1
PTPN20 protein tyrosine phosphatase, non-receptor type 20
PTPRE protein tyrosine phosphatase, receptor type, E
PYY2 peptide YY, 2 (pseudogene)
QPRT quinolinate phosphoribosyltransferase
RAB36 RAB36, member RAS oncogene family
RAB9BP1 RAB9B, member RAS oncogene family pseudogene 1
RALGDS ral guanine nucleotide dissociation stimulator
RBM6 RNA binding motif protein 6
RDH13 retinol dehydrogenase 13 (all-trans/9-cis)
REN renin
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RHEBL1 Ras homolog enriched in brain like 1
RNASE11 ribonuclease, RNase A family, 11 (non-active)
RNF2 ring finger protein 2
RNFT2 ring finger protein, transmembrane 2
RPL29P2 ribosomal protein L29 pseudogene 2
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RRAGA Ras-related GTP binding A
RSPRY1 ring finger and SPRY domain containing 1
RTP1 receptor (chemosensory) transporter protein 1
S100A2 S100 calcium binding protein A2
SCARA3 scavenger receptor class A, member 3
SCG2 secretogranin II
SCHIP1 schwannomin interacting protein 1
SCN9A sodium channel, voltage gated, type IX alpha subunit
SCRT1 scratch family zinc finger 1
SDCBP2 syndecan binding protein (syntenin) 2
SDHAP1 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1
SDSL serine dehydratase-like
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEPP1 selenoprotein P, plasma, 1
SEPT7P9 septin 7 pseudogene 9
SERTAD2 SERTA domain containing 2
SFXN3 sideroflexin 3
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SIGLEC6 sialic acid binding Ig-like lectin 6
SIGLECL1 SIGLEC family like 1
SIK3 SIK family kinase 3
SIL1 SIL1 nucleotide exchange factor
SLC25A53 solute carrier family 25, member 53
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC35E2 solute carrier family 35, member E2
SLC38A10 solute carrier family 38, member 10
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
SLC7A6OS solute carrier family 7, member 6 opposite strand
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SLCO1B7 solute carrier organic anion transporter family, member 1B7 (non-functional)
SNAI3 snail family zinc finger 3
SNAP47 synaptosomal-associated protein, 47kDa
SNHG20 small nucleolar RNA host gene 20
SNHG4 small nucleolar RNA host gene 4
SNORA46 small nucleolar RNA, H/ACA box 46
SOCS5 suppressor of cytokine signaling 5
SPATA12 spermatogenesis associated 12
SPATA17 spermatogenesis associated 17
SPATS2 spermatogenesis associated, serine-rich 2
SPNS2 spinster homolog 2 (Drosophila)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SS18 synovial sarcoma translocation, chromosome 18
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
STEAP1 six transmembrane epithelial antigen of the prostate 1
STK36 serine/threonine kinase 36
STOML3 stomatin (EPB72)-like 3
STON2 stonin 2
SVIL supervillin
SYNJ2 synaptojanin 2
SYS1-DBNDD2 SYS1-DBNDD2 readthrough (NMD candidate)
TAGLN2 transgelin 2
TBC1D15 TBC1 domain family, member 15
TBC1D16 TBC1 domain family, member 16
TCTA T-cell leukemia translocation altered
TCTN2 tectonic family member 2
TEC tec protein tyrosine kinase
TEKT4 tektin 4
TESPA1 thymocyte expressed, positive selection associated 1
TFB2M transcription factor B2, mitochondrial
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TLE3 transducin-like enhancer of split 3
TM4SF1 transmembrane 4 L six family member 1
TMEM187 transmembrane protein 187
TMEM43 transmembrane protein 43
TPD52 tumor protein D52
TPM4 tropomyosin 4
TRAF4 TNF receptor-associated factor 4
TREML2 triggering receptor expressed on myeloid cells-like 2
TRIM15 tripartite motif containing 15
TRIM16 tripartite motif containing 16
TRIM16L tripartite motif containing 16-like
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TRUB1 TruB pseudouridine (psi) synthase family member 1
TSPAN2 tetraspanin 2
TSTA3 tissue specific transplantation antigen P35B
TTC27 tetratricopeptide repeat domain 27
TTC30A tetratricopeptide repeat domain 30A
TTC30B tetratricopeptide repeat domain 30B
TTC5 tetratricopeptide repeat domain 5
TUBA1A tubulin, alpha 1a
TUBB6 tubulin, beta 6 class V
TXK TXK tyrosine kinase
UBQLN2 ubiquilin 2
UBXN10 UBX domain protein 10
ULK4P3 ULK4 pseudogene 3
USP40 ubiquitin specific peptidase 40
USP54 ubiquitin specific peptidase 54
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
UST uronyl-2-sulfotransferase
VANGL1 VANGL planar cell polarity protein 1
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
VSTM4 V-set and transmembrane domain containing 4
VSTM5 V-set and transmembrane domain containing 5
VWA7 von Willebrand factor A domain containing 7
WDR31 WD repeat domain 31
WDR66 WD repeat domain 66
WDR77 WD repeat domain 77
WDR78 WD repeat domain 78
WDR86 WD repeat domain 86
WNT7B wingless-type MMTV integration site family, member 7B
WNT9A wingless-type MMTV integration site family, member 9A
XPC xeroderma pigmentosum, complementation group C
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZBTB42 zinc finger and BTB domain containing 42
ZBTB46 zinc finger and BTB domain containing 46
ZDHHC15 zinc finger, DHHC-type containing 15
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZMYND12 zinc finger, MYND-type containing 12
ZSCAN31 zinc finger and SCAN domain containing 31
ZSCAN9 zinc finger and SCAN domain containing 9

low expression

Symbol Name
FYCO1 FYVE and coiled-coil domain containing 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SMIM7 small integral membrane protein 7
XPA xeroderma pigmentosum, complementation group A