Acute Myeloid Leukemia_LAML_TCGA-AB-2948-03A-01T-0740-13 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Acute Myeloid Leukemia_LAML (The Cancer Genome Atlas)
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425 genes with high or low expression in Acute Myeloid Leukemia_LAML_TCGA-AB-2948-03A-01T-0740-13 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACHE acetylcholinesterase (Yt blood group)
ACSL6 acyl-CoA synthetase long-chain family member 6
ADAM7 ADAM metallopeptidase domain 7
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAP1 ArfGAP with dual PH domains 1
ADCY7 adenylate cyclase 7
ADIRF adipogenesis regulatory factor
ADRBK1 adrenergic, beta, receptor kinase 1
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3
ALAD aminolevulinate dehydratase
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2
ANKRD13D ankyrin repeat domain 13 family, member D
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANKRD37 ankyrin repeat domain 37
ANO5 anoctamin 5
ANXA9 annexin A9
AP4B1 adaptor-related protein complex 4, beta 1 subunit
APCDD1 adenomatosis polyposis coli down-regulated 1
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
AQP4 aquaporin 4
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGAP24 Rho GTPase activating protein 24
ARHGAP30 Rho GTPase activating protein 30
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF37 Rho guanine nucleotide exchange factor (GEF) 37
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARSG arylsulfatase G
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASB2 ankyrin repeat and SOCS box containing 2
ASGR1 asialoglycoprotein receptor 1
ASGR2 asialoglycoprotein receptor 2
ASRGL1 asparaginase like 1
ATG4A autophagy related 4A, cysteine peptidase
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
AWAT1 acyl-CoA wax alcohol acyltransferase 1
BCL6 B-cell CLL/lymphoma 6
BLVRB biliverdin reductase B
BRDT bromodomain, testis-specific
BSND barttin CLCNK-type chloride channel accessory beta subunit
BVES blood vessel epicardial substance
C10ORF111 chromosome 10 open reading frame 111
C11ORF21 chromosome 11 open reading frame 21
C14ORF39 chromosome 14 open reading frame 39
C16ORF92 chromosome 16 open reading frame 92
C17ORF99 chromosome 17 open reading frame 99
C19ORF38 chromosome 19 open reading frame 38
C1ORF115 chromosome 1 open reading frame 115
C2CD4D C2 calcium-dependent domain containing 4D
C3 complement component 3
C8ORF31 chromosome 8 open reading frame 31
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAPG capping protein (actin filament), gelsolin-like
CAPN2 calpain 2, (m/II) large subunit
CAST calpastatin
CCDC88B coiled-coil domain containing 88B
CCND3 cyclin D3
CCNI2 cyclin I family, member 2
CD101 CD101 molecule
CD1E CD1e molecule
CD200R1 CD200 receptor 1
CD300C CD300c molecule
CD300LB CD300 molecule-like family member b
CD4 CD4 molecule
CDA cytidine deaminase
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDRT15 CMT1A duplicated region transcript 15
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CFAP58 cilia and flagella associated protein 58
CKAP4 cytoskeleton-associated protein 4
CLEC1A C-type lectin domain family 1, member A
CLEC4A C-type lectin domain family 4, member A
CLEC6A C-type lectin domain family 6, member A
CLK4 CDC-like kinase 4
CMTM4 CKLF-like MARVEL transmembrane domain containing 4
COL9A2 collagen, type IX, alpha 2
COPZ2 coatomer protein complex, subunit zeta 2
CORO7 coronin 7
CPT1B carnitine palmitoyltransferase 1B (muscle)
CRIP3 cysteine-rich protein 3
CTNNA3 catenin (cadherin-associated protein), alpha 3
CTSH cathepsin H
CTSZ cathepsin Z
CUZD1 CUB and zona pellucida-like domains 1
CXORF49B chromosome X open reading frame 49B
CYB561D2 cytochrome b561 family, member D2
CYP1B1-AS1 CYP1B1 antisense RNA 1
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
DCBLD1 discoidin, CUB and LCCL domain containing 1
DCLK3 doublecortin-like kinase 3
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DGAT2 diacylglycerol O-acyltransferase 2
DLEC1 deleted in lung and esophageal cancer 1
DMBX1 diencephalon/mesencephalon homeobox 1
DNER delta/notch-like EGF repeat containing
DTX4 deltex 4, E3 ubiquitin ligase
DUOX1 dual oxidase 1
DUOX2 dual oxidase 2
DUOXA1 dual oxidase maturation factor 1
DUOXA2 dual oxidase maturation factor 2
DUSP22 dual specificity phosphatase 22
DYSF dysferlin
E2F2 E2F transcription factor 2
E2F7 E2F transcription factor 7
EDA ectodysplasin A
EHF ets homologous factor
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
ELMO3 engulfment and cell motility 3
ELMOD3 ELMO/CED-12 domain containing 3
EPHA1 EPH receptor A1
EPHX4 epoxide hydrolase 4
EVC Ellis van Creveld protein
EVC2 Ellis van Creveld syndrome 2
EVPLL envoplakin-like
EXD1 exonuclease 3'-5' domain containing 1
F5 coagulation factor V (proaccelerin, labile factor)
FAM118A family with sequence similarity 118, member A
FAM138E family with sequence similarity 138, member E
FAM151B family with sequence similarity 151, member B
FAM200B family with sequence similarity 200, member B
FAM27C family with sequence similarity 27, member C
FAM65C family with sequence similarity 65, member C
FBN2 fibrillin 2
FBXO9 F-box protein 9
FCAR Fc fragment of IgA receptor
FCHO1 FCH domain only 1
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGR FGR proto-oncogene, Src family tyrosine kinase
FKBP15 FK506 binding protein 15, 133kDa
FLII flightless I homolog (Drosophila)
FLNA filamin A, alpha
FOLR3 folate receptor 3 (gamma)
GABPB2 GA binding protein transcription factor, beta subunit 2
GAGE10 G antigen 10
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GAP43 growth associated protein 43
GGT8P gamma-glutamyltransferase 8 pseudogene
GIMAP1 GTPase, IMAP family member 1
GNG8 guanine nucleotide binding protein (G protein), gamma 8
GOLM1 golgi membrane protein 1
GPR132 G protein-coupled receptor 132
GPR141 G protein-coupled receptor 141
GPR15 G protein-coupled receptor 15
GPR35 G protein-coupled receptor 35
GPR84 G protein-coupled receptor 84
GRN granulin
GSAP gamma-secretase activating protein
GSTT1 glutathione S-transferase theta 1
GTPBP2 GTP binding protein 2
GYPB glycophorin B (MNS blood group)
HCLS1 hematopoietic cell-specific Lyn substrate 1
HDAC3 histone deacetylase 3
HEPACAM2 HEPACAM family member 2
HEXB hexosaminidase B (beta polypeptide)
HIST1H4G histone cluster 1, H4g
HK3 hexokinase 3 (white cell)
HMBS hydroxymethylbilane synthase
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HMGN2P46 high mobility group nucleosomal binding domain 2 pseudogene 46
HSPA12B heat shock 70kD protein 12B
IFITM4P interferon induced transmembrane protein 4 pseudogene
IFNA7 interferon, alpha 7
IGSF3 immunoglobulin superfamily, member 3
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL17A interleukin 17A
IL1RN interleukin 1 receptor antagonist
IL6R interleukin 6 receptor
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INS-IGF2 INS-IGF2 readthrough
IQSEC1 IQ motif and Sec7 domain 1
IRF5 interferon regulatory factor 5
IRS1 insulin receptor substrate 1
ISL2 ISL LIM homeobox 2
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB7 integrin, beta 7
ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein
JUN jun proto-oncogene
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KIAA0040 KIAA0040
KIAA0319L KIAA0319-like
KIAA1211L KIAA1211-like
KLF4 Kruppel-like factor 4 (gut)
KLHDC8A kelch domain containing 8A
KLK1 kallikrein 1
KLK10 kallikrein-related peptidase 10
KLK15 kallikrein-related peptidase 15
KLK2 kallikrein-related peptidase 2
KRT12 keratin 12, type I
KRT39 keratin 39, type I
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LIN7A lin-7 homolog A (C. elegans)
LINC00293 long intergenic non-protein coding RNA 293
LINC01547 long intergenic non-protein coding RNA 1547
LOC100132111 uncharacterized LOC100132111
LOC388242 coiled-coil domain containing 101 pseudogene
LOC400794 uncharacterized LOC400794
LOC402644 peptidylprolyl isomerase A (cyclophilin A) pseudogene
LOR loricrin
LRP3 low density lipoprotein receptor-related protein 3
LRRC20 leucine rich repeat containing 20
LRRC74A leucine rich repeat containing 74A
LRRC8D leucine rich repeat containing 8 family, member D
LSP1 lymphocyte-specific protein 1
LTA4H leukotriene A4 hydrolase
LTB4R leukotriene B4 receptor
LY6G6D lymphocyte antigen 6 complex, locus G6D
LYST lysosomal trafficking regulator
MALT1 MALT1 paracaspase
MAN1C1 mannosidase, alpha, class 1C, member 1
MAN2B2 mannosidase, alpha, class 2B, member 2
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K6 mitogen-activated protein kinase kinase 6
MAPK14 mitogen-activated protein kinase 14
MARC1 mitochondrial amidoxime reducing component 1
MCEMP1 mast cell-expressed membrane protein 1
MCOLN3 mucolipin 3
MEGF9 multiple EGF-like-domains 9
MFSD7 major facilitator superfamily domain containing 7
MGAM maltase-glucoamylase
MGC72080 MGC72080 pseudogene
MICB MHC class I polypeptide-related sequence B
MID2 midline 2
MINK1 misshapen-like kinase 1
MLN motilin
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP25 matrix metallopeptidase 25
MON1B MON1 secretory trafficking family member B
MORC4 MORC family CW-type zinc finger 4
MPPE1 metallophosphoesterase 1
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MSL3 male-specific lethal 3 homolog (Drosophila)
MSRB1 methionine sulfoxide reductase B1
MTF1 metal-regulatory transcription factor 1
MTMR11 myotubularin related protein 11
MTMR14 myotubularin related protein 14
MTMR3 myotubularin related protein 3
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYO1F myosin IF
MYO3A myosin IIIA
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAGA N-acetylgalactosaminidase, alpha-
NBPF15 neuroblastoma breakpoint family, member 15
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NECAB2 N-terminal EF-hand calcium binding protein 2
NEK9 NIMA-related kinase 9
NFAM1 NFAT activating protein with ITAM motif 1
NHEG1 neuroblastoma highly expressed 1
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
NHSL2 NHS-like 2
NLRP1 NLR family, pyrin domain containing 1
NLRP12 NLR family, pyrin domain containing 12
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOBOX NOBOX oogenesis homeobox
NOD2 nucleotide-binding oligomerization domain containing 2
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
NPTN neuroplastin
NRK Nik related kinase
OLFML1 olfactomedin-like 1
OR10G3 olfactory receptor, family 10, subfamily G, member 3
OR11G2 olfactory receptor, family 11, subfamily G, member 2
OR4D6 olfactory receptor, family 4, subfamily D, member 6
OR52A5 olfactory receptor, family 52, subfamily A, member 5
OXA1L oxidase (cytochrome c) assembly 1-like
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1
PABPC1L2B poly(A) binding protein, cytoplasmic 1-like 2B
PADI4 peptidyl arginine deiminase, type IV
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCSK5 proprotein convertase subtilisin/kexin type 5
PECR peroxisomal trans-2-enoyl-CoA reductase
PEPD peptidase D
PGAM4 phosphoglycerate mutase family member 4
PHF2 PHD finger protein 2
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene)
PKD1L3 polycystic kidney disease 1-like 3
PKDCC protein kinase domain containing, cytoplasmic
PKM pyruvate kinase, muscle
PLA2G2C phospholipase A2, group IIC
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLBD1 phospholipase B domain containing 1
PLCL1 phospholipase C-like 1
PM20D1 peptidase M20 domain containing 1
PNMAL2 paraneoplastic Ma antigen family-like 2
PNPLA1 patatin-like phospholipase domain containing 1
POPDC3 popeye domain containing 3
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPEF1 protein phosphatase, EF-hand calcium binding domain 1
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPT1 palmitoyl-protein thioesterase 1
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCDBP protein kinase C, delta binding protein
PSKH2 protein serine kinase H2
PSRC1 proline/serine-rich coiled-coil 1
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTPN20 protein tyrosine phosphatase, non-receptor type 20
PXYLP1 2-phosphoxylose phosphatase 1
PYGO1 pygopus family PHD finger 1
QPCT glutaminyl-peptide cyclotransferase
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB19 RAB19, member RAS oncogene family
RAB24 RAB24, member RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RASSF3 Ras association (RalGDS/AF-6) domain family member 3
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
REG4 regenerating islet-derived family, member 4
RETN resistin
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RNF152 ring finger protein 152
RNF165 ring finger protein 165
RXRA retinoid X receptor, alpha
S100A3 S100 calcium binding protein A3
SCML1 sex comb on midleg-like 1 (Drosophila)
SCN7A sodium channel, voltage gated, type VII alpha subunit
SEC14L4 SEC14-like 4 (S. cerevisiae)
SEC24C SEC24 family member C
SELENBP1 selenium binding protein 1
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SEZ6L seizure related 6 homolog (mouse)-like
SFXN5 sideroflexin 5
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SGSH N-sulfoglucosamine sulfohydrolase
SIGLEC14 sialic acid binding Ig-like lectin 14
SIGLEC9 sialic acid binding Ig-like lectin 9
SIRPB1 signal-regulatory protein beta 1
SIRPB2 signal-regulatory protein beta 2
SIRPD signal-regulatory protein delta
SLC12A8 solute carrier family 12, member 8
SLC22A15 solute carrier family 22, member 15
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC26A11 solute carrier family 26 (anion exchanger), member 11
SLC26A8 solute carrier family 26 (anion exchanger), member 8
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1
SLC35A4 solute carrier family 35, member A4
SLC35G1 solute carrier family 35, member G1
SLC37A3 solute carrier family 37, member 3
SLC46A2 solute carrier family 46, member 2
SLC6A10P solute carrier family 6 (neurotransmitter transporter), member 10, pseudogene
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNORA11 small nucleolar RNA, H/ACA box 11
SNORA64 small nucleolar RNA, H/ACA box 64
SNORA79 small nucleolar RNA, H/ACA box 79
SNX21 sorting nexin family member 21
SNX7 sorting nexin 7
SPESP1 sperm equatorial segment protein 1
SPIN3 spindlin family, member 3
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPRR2F small proline-rich protein 2F
SRA1 steroid receptor RNA activator 1
SRXN1 sulfiredoxin 1
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAG3 stromal antigen 3
STX3 syntaxin 3
SYK spleen tyrosine kinase
SYN1 synapsin I
SYT1 synaptotagmin I
TAC3 tachykinin 3
TANGO2 transport and golgi organization 2 homolog (Drosophila)
TAS2R60 taste receptor, type 2, member 60
TBC1D12 TBC1 domain family, member 12
TBC1D3F TBC1 domain family, member 3F
TGM3 transglutaminase 3
THBS4 thrombospondin 4
TKT transketolase
TM9SF4 transmembrane 9 superfamily protein member 4
TMCO6 transmembrane and coiled-coil domains 6
TMEM116 transmembrane protein 116
TMEM133 transmembrane protein 133
TMEM154 transmembrane protein 154
TMEM55A transmembrane protein 55A
TMEM79 transmembrane protein 79
TMEM8B transmembrane protein 8B
TMTC1 transmembrane and tetratricopeptide repeat containing 1
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNS1 tensin 1
TRAF3IP3 TRAF3 interacting protein 3
TRIM10 tripartite motif containing 10
TRIM2 tripartite motif containing 2
TRIM7 tripartite motif containing 7
TSPO2 translocator protein 2
TTTY2 testis-specific transcript, Y-linked 2 (non-protein coding)
TUBA4A tubulin, alpha 4a
TWIST2 twist family bHLH transcription factor 2
TYK2 tyrosine kinase 2
UBTD1 ubiquitin domain containing 1
UBXN11 UBX domain protein 11
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
UNC119 unc-119 homolog (C. elegans)
UPK3A uroplakin 3A
UVSSA UV-stimulated scaffold protein A
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VNN3 vanin 3
WFDC10B WAP four-disulfide core domain 10B
WIF1 WNT inhibitory factor 1
WLS wntless Wnt ligand secretion mediator
XRCC6BP1 XRCC6 binding protein 1
ZBED9 zinc finger, BED-type containing 9
ZBTB47 zinc finger and BTB domain containing 47
ZBTB7B zinc finger and BTB domain containing 7B
ZC2HC1A zinc finger, C2HC-type containing 1A
ZFP57 ZFP57 zinc finger protein
ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate)
ZNF318 zinc finger protein 318
ZNF319 zinc finger protein 319
ZNF641 zinc finger protein 641