Acute Myeloid Leukemia_LAML_TCGA-AB-2954-03A-01T-0736-13 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Acute Myeloid Leukemia_LAML (The Cancer Genome Atlas)
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254 genes with high or low expression in Acute Myeloid Leukemia_LAML_TCGA-AB-2954-03A-01T-0736-13 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AANAT aralkylamine N-acetyltransferase
ACTL10 actin-like 10
ADAM15 ADAM metallopeptidase domain 15
ADIG adipogenin
AFAP1 actin filament associated protein 1
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
AK5 adenylate kinase 5
ALK anaplastic lymphoma receptor tyrosine kinase
ANKRD13B ankyrin repeat domain 13B
ANPEP alanyl (membrane) aminopeptidase
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARC activity-regulated cytoskeleton-associated protein
ARHGAP27 Rho GTPase activating protein 27
ASAP1-IT1 ASAP1 intronic transcript 1
ASGR2 asialoglycoprotein receptor 2
ATOH8 atonal homolog 8 (Drosophila)
BAIAP3 BAI1-associated protein 3
C11ORF16 chromosome 11 open reading frame 16
C16ORF90 chromosome 16 open reading frame 90
C1ORF110 chromosome 1 open reading frame 110
C1ORF115 chromosome 1 open reading frame 115
C1ORF189 chromosome 1 open reading frame 189
C1QTNF8 C1q and tumor necrosis factor related protein 8
C20ORF144 chromosome 20 open reading frame 144
C20ORF173 chromosome 20 open reading frame 173
C2ORF61 chromosome 2 open reading frame 61
C3ORF20 chromosome 3 open reading frame 20
C7ORF65 chromosome 7 open reading frame 65
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CALHM1 calcium homeostasis modulator 1
CARD14 caspase recruitment domain family, member 14
CCDC116 coiled-coil domain containing 116
CCDC88C coiled-coil domain containing 88C
CCDC96 coiled-coil domain containing 96
CCIN calicin
CCM2 cerebral cavernous malformation 2
CDC123 cell division cycle 123
CDR2L cerebellar degeneration-related protein 2-like
CEND1 cell cycle exit and neuronal differentiation 1
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CKB creatine kinase, brain
CLIP3 CAP-GLY domain containing linker protein 3
COL10A1 collagen, type X, alpha 1
COL8A2 collagen, type VIII, alpha 2
CPA1 carboxypeptidase A1 (pancreatic)
CPA2 carboxypeptidase A2 (pancreatic)
CRIP3 cysteine-rich protein 3
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1
DEGS2 delta(4)-desaturase, sphingolipid 2
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DGCR2 DiGeorge syndrome critical region gene 2
DHH desert hedgehog
DISC1 disrupted in schizophrenia 1
DISC2 disrupted in schizophrenia 2 (non-protein coding)
DOCK4 dedicator of cytokinesis 4
DPYSL3 dihydropyrimidinase-like 3
EDDM3B epididymal protein 3B
EEF1DP3 eukaryotic translation elongation factor 1 delta pseudogene 3
EGR2 early growth response 2
EGR4 early growth response 4
EIF3CL eukaryotic translation initiation factor 3, subunit C-like
ENHO energy homeostasis associated
EPHB2 EPH receptor B2
EXD1 exonuclease 3'-5' domain containing 1
EXOC3L2 exocyst complex component 3-like 2
F2RL2 coagulation factor II (thrombin) receptor-like 2
FAM166B family with sequence similarity 166, member B
FAM181A family with sequence similarity 181, member A
FAM196B family with sequence similarity 196, member B
FAM213B family with sequence similarity 213, member B
FAM24A family with sequence similarity 24, member A
FAM43A family with sequence similarity 43, member A
FAM53A family with sequence similarity 53, member A
FAM58A family with sequence similarity 58, member A
FBXL22 F-box and leucine-rich repeat protein 22
FFAR4 free fatty acid receptor 4
FGF11 fibroblast growth factor 11
FILIP1L filamin A interacting protein 1-like
FLT4 fms-related tyrosine kinase 4
FSCN3 fascin actin-bundling protein 3, testicular
GAS2L1 growth arrest-specific 2 like 1
GBX1 gastrulation brain homeobox 1
GFRA4 GDNF family receptor alpha 4
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPER1 G protein-coupled estrogen receptor 1
GPR52 G protein-coupled receptor 52
GRHL2 grainyhead-like 2 (Drosophila)
H1FOO H1 histone family, member O, oocyte-specific
HAGHL hydroxyacylglutathione hydrolase-like
HPYR1 Helicobacter pylori responsive 1 (non-protein coding)
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IFT74 intraflagellar transport 74
IL17C interleukin 17C
INE2 inactivation escape 2 (non-protein coding)
ISYNA1 inositol-3-phosphate synthase 1
KANK3 KN motif and ankyrin repeat domains 3
KCNK13 potassium channel, two pore domain subfamily K, member 13
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KRTAP4-11 keratin associated protein 4-11
LCN6 lipocalin 6
LMO3 LIM domain only 3 (rhombotin-like 2)
LOC100130238 uncharacterized LOC100130238
LOC389332 uncharacterized LOC389332
LPAR1 lysophosphatidic acid receptor 1
LRP4 low density lipoprotein receptor-related protein 4
LRRN4 leucine rich repeat neuronal 4
LRRTM2 leucine rich repeat transmembrane neuronal 2
METRN meteorin, glial cell differentiation regulator
MGC16025 uncharacterized LOC85009
MKL1 megakaryoblastic leukemia (translocation) 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MN1 meningioma (disrupted in balanced translocation) 1
MUSK muscle, skeletal, receptor tyrosine kinase
MYH11 myosin, heavy chain 11, smooth muscle
MYH9 myosin, heavy chain 9, non-muscle
MYO1C myosin IC
NAGA N-acetylgalactosaminidase, alpha-
NAGS N-acetylglutamate synthase
NHLH1 nescient helix loop helix 1
NMRAL1 NmrA-like family domain containing 1
NPTX2 neuronal pentraxin II
NTHL1 nth endonuclease III-like 1 (E. coli)
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5
NXPH3 neurexophilin 3
OR10J3 olfactory receptor, family 10, subfamily J, member 3
OR1A2 olfactory receptor, family 1, subfamily A, member 2
OR52B2 olfactory receptor, family 52, subfamily B, member 2
OR52W1 olfactory receptor, family 52, subfamily W, member 1
OR5B21 olfactory receptor, family 5, subfamily B, member 21
OR7E91P olfactory receptor, family 7, subfamily E, member 91 pseudogene
OTOP2 otopetrin 2
PAOX polyamine oxidase (exo-N4-amino)
PAPOLB poly(A) polymerase beta (testis specific)
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PAQR5 progestin and adipoQ receptor family member V
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PISD phosphatidylserine decarboxylase
PLCD3 phospholipase C, delta 3
PLD2 phospholipase D2
PLXNA2 plexin A2
PLXNB2 plexin B2
POU5F2 POU domain class 5, transcription factor 2
PRB1 proline-rich protein BstNI subfamily 1
PRB2 proline-rich protein BstNI subfamily 2
PRB3 proline-rich protein BstNI subfamily 3
PRCD progressive rod-cone degeneration
PRKX protein kinase, X-linked
PRSS58 protease, serine, 58
PTGFRN prostaglandin F2 receptor inhibitor
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTPRH protein tyrosine phosphatase, receptor type, H
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
QRFP pyroglutamylated RFamide peptide
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB26 RAB26, member RAS oncogene family
RAB43 RAB43, member RAS oncogene family
RADIL Ras association and DIL domains
RAET1E retinoic acid early transcript 1E
RAET1G retinoic acid early transcript 1G
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RAPSN receptor-associated protein of the synapse
RASL10A RAS-like, family 10, member A
RGMA repulsive guidance molecule family member a
RLN3 relaxin 3
RPS6KL1 ribosomal protein S6 kinase-like 1
RPTN repetin
RUFY1 RUN and FYVE domain containing 1
SCARNA18 small Cajal body-specific RNA 18
SCARNA21 small Cajal body-specific RNA 21
SCARNA22 small Cajal body-specific RNA 22
SCTR secretin receptor
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1
SLC35E4 solute carrier family 35, member E4
SLC36A3 solute carrier family 36, member 3
SLC38A8 solute carrier family 38, member 8
SLC4A11 solute carrier family 4, sodium borate transporter, member 11
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMAD6 SMAD family member 6
SNAI3 snail family zinc finger 3
SNORA38B small nucleolar RNA, H/ACA box 38B
SNORA46 small nucleolar RNA, H/ACA box 46
SNORA77 small nucleolar RNA, H/ACA box 77
SNORA78 small nucleolar RNA, H/ACA box 78
SNTA1 syntrophin, alpha 1
SOX15 SRY (sex determining region Y)-box 15
SPATA32 spermatogenesis associated 32
STARD8 StAR-related lipid transfer (START) domain containing 8
SULF2 sulfatase 2
TBC1D3P2 TBC1 domain family, member 3 pseudogene 2
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TEAD4 TEA domain family member 4
TFCP2L1 transcription factor CP2-like 1
THAP8 THAP domain containing 8
TM4SF20 transmembrane 4 L six family member 20
TMEM132A transmembrane protein 132A
TMEM191A transmembrane protein 191A (pseudogene)
TMEM240 transmembrane protein 240
TMEM38A transmembrane protein 38A
TNF tumor necrosis factor
TOR4A torsin family 4, member A
TRIM47 tripartite motif containing 47
TRIM65 tripartite motif containing 65
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
VASN vasorin
VIPR1 vasoactive intestinal peptide receptor 1
WFDC5 WAP four-disulfide core domain 5
WNT4 wingless-type MMTV integration site family, member 4
WWC2 WW and C2 domain containing 2
WWC2-AS2 WWC2 antisense RNA 2
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
ZACN zinc activated ligand-gated ion channel
ZAR1L zygote arrest 1-like
ZNF296 zinc finger protein 296
ZNF467 zinc finger protein 467
ZNF705D zinc finger protein 705D

low expression

Symbol Name
ADAT1 adenosine deaminase, tRNA-specific 1
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
ATXN1L ataxin 1-like
CBFB core-binding factor, beta subunit
CIRH1A cirrhosis, autosomal recessive 1A (cirhin)
CRY1 cryptochrome circadian clock 1
CTCF CCCTC-binding factor (zinc finger protein)
CYB5B cytochrome b5 type B (outer mitochondrial membrane)
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
DHODH dihydroorotate dehydrogenase (quinone)
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DYNLT3 dynein, light chain, Tctex-type 3
FBXO25 F-box protein 25
FOPNL FGFR1OP N-terminal like
GABARAPL2 GABA(A) receptor-associated protein-like 2
KARS lysyl-tRNA synthetase
METTL6 methyltransferase like 6
NIP7 NIP7, nucleolar pre-rRNA processing protein
PBLD phenazine biosynthesis-like protein domain containing
PEX19 peroxisomal biogenesis factor 19
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
PRPF18 pre-mRNA processing factor 18
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
RPP30 ribonuclease P/MRP 30kDa subunit
SF3B3 splicing factor 3b, subunit 3, 130kDa
SLC7A6OS solute carrier family 7, member 6 opposite strand
TBC1D22B TBC1 domain family, member 22B
TERF2IP telomeric repeat binding factor 2, interacting protein
TOX4 TOX high mobility group box family member 4
TXNL4B thioredoxin-like 4B
WWOX WW domain containing oxidoreductase