Acute Myeloid Leukemia_LAML_TCGA-AB-2970-03A-01T-0734-13 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Acute Myeloid Leukemia_LAML (The Cancer Genome Atlas)
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424 genes with high or low expression in Acute Myeloid Leukemia_LAML_TCGA-AB-2970-03A-01T-0734-13 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9
ABHD15 abhydrolase domain containing 15
ACSL3 acyl-CoA synthetase long-chain family member 3
ACVR2A activin A receptor, type IIA
ADORA1 adenosine A1 receptor
AFF3 AF4/FMR2 family, member 3
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9
AHNAK2 AHNAK nucleoprotein 2
AKAP7 A kinase (PRKA) anchor protein 7
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
AMICA1 adhesion molecule, interacts with CXADR antigen 1
AMIGO2 adhesion molecule with Ig-like domain 2
ANGEL2 angel homolog 2 (Drosophila)
ANKRD12 ankyrin repeat domain 12
ANKRD36BP1 ankyrin repeat domain 36B pseudogene 1
APP amyloid beta (A4) precursor protein
ARHGAP17 Rho GTPase activating protein 17
ARL5C ADP-ribosylation factor-like 5C
ARR3 arrestin 3, retinal (X-arrestin)
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATG4C autophagy related 4C, cysteine peptidase
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
AXDND1 axonemal dynein light chain domain containing 1
BCAR3 breast cancer anti-estrogen resistance 3
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL7A B-cell CLL/lymphoma 7A
BCOR BCL6 corepressor
BEND4 BEN domain containing 4
BET1 Bet1 golgi vesicular membrane trafficking protein
BLNK B-cell linker
BORA bora, aurora kinase A activator
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
BTBD16 BTB (POZ) domain containing 16
C11ORF70 chromosome 11 open reading frame 70
C12ORF45 chromosome 12 open reading frame 45
C12ORF75 chromosome 12 open reading frame 75
C15ORF59 chromosome 15 open reading frame 59
C16ORF89 chromosome 16 open reading frame 89
C1ORF110 chromosome 1 open reading frame 110
C1QL4 complement component 1, q subcomponent-like 4
C5ORF34 chromosome 5 open reading frame 34
C6ORF15 chromosome 6 open reading frame 15
C6ORF58 chromosome 6 open reading frame 58
C7ORF31 chromosome 7 open reading frame 31
C7ORF33 chromosome 7 open reading frame 33
CABP1 calcium binding protein 1
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CADM4 cell adhesion molecule 4
CALCA calcitonin-related polypeptide alpha
CAPS2 calcyphosine 2
CARD11 caspase recruitment domain family, member 11
CBLN4 cerebellin 4 precursor
CCDC18 coiled-coil domain containing 18
CCDC183 coiled-coil domain containing 183
CCDC88A coiled-coil domain containing 88A
CCNG2 cyclin G2
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CCSAP centriole, cilia and spindle-associated protein
CD2AP CD2-associated protein
CD300LD CD300 molecule-like family member d
CD3EAP CD3e molecule, epsilon associated protein
CDC40 cell division cycle 40
CDHR5 cadherin-related family member 5
CDYL chromodomain protein, Y-like
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CEP120 centrosomal protein 120kDa
CFAP74 cilia and flagella associated protein 74
CHL1 cell adhesion molecule L1-like
CIB2 calcium and integrin binding family member 2
CLCN5 chloride channel, voltage-sensitive 5
CLEC10A C-type lectin domain family 10, member A
CLEC4C C-type lectin domain family 4, member C
CLLU1OS chronic lymphocytic leukemia up-regulated 1 opposite strand
CMKLR1 chemerin chemokine-like receptor 1
CNGB3 cyclic nucleotide gated channel beta 3
CNTN6 contactin 6
COL4A4 collagen, type IV, alpha 4
CPVL carboxypeptidase, vitellogenic-like
CPXM2 carboxypeptidase X (M14 family), member 2
CREB1 cAMP responsive element binding protein 1
CRYBG3 beta-gamma crystallin domain containing 3
CRYM-AS1 CRYM antisense RNA 1
CTCFL CCCTC-binding factor (zinc finger protein)-like
CTSV cathepsin V
CUX2 cut-like homeobox 2
CX3CL1 chemokine (C-X3-C motif) ligand 1
CYYR1 cysteine/tyrosine-rich 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DACT1 dishevelled-binding antagonist of beta-catenin 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF8L1 DDB1 and CUL4 associated factor 8-like 1
DCK deoxycytidine kinase
DCTN5 dynactin 5 (p25)
DDHD1 DDHD domain containing 1
DENND5B DENN/MADD domain containing 5B
DEPDC1 DEP domain containing 1
DERL3 derlin 3
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DKFZP586I1420 uncharacterized protein DKFZp586I1420
DLX6 distal-less homeobox 6
DNASE1L3 deoxyribonuclease I-like 3
DNER delta/notch-like EGF repeat containing
DPP4 dipeptidyl-peptidase 4
DPPA3 developmental pluripotency associated 3
DPT dermatopontin
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DTX4 deltex 4, E3 ubiquitin ligase
E2F7 E2F transcription factor 7
ECHDC1 ethylmalonyl-CoA decarboxylase 1
EGFR epidermal growth factor receptor
EHF ets homologous factor
ELOVL2 ELOVL fatty acid elongase 2
ENAH enabled homolog (Drosophila)
ENAM enamelin
ENHO energy homeostasis associated
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EPHB1 EPH receptor B1
ERN1 endoplasmic reticulum to nucleus signaling 1
EWSAT1 Ewing sarcoma associated transcript 1
FAM129C family with sequence similarity 129, member C
FAM138B family with sequence similarity 138, member B
FAM138D family with sequence similarity 138, member D
FAM167A-AS1 FAM167A antisense RNA 1
FAM220A family with sequence similarity 220, member A
FAM221B family with sequence similarity 221, member B
FAM43A family with sequence similarity 43, member A
FAM72A family with sequence similarity 72, member A
FAM72B family with sequence similarity 72, member B
FAM72D family with sequence similarity 72, member D
FAM81A family with sequence similarity 81, member A
FBXL3 F-box and leucine-rich repeat protein 3
FBXO47 F-box protein 47
FBXO48 F-box protein 48
FBXO5 F-box protein 5
FCRLA Fc receptor-like A
FDPSP2 farnesyl diphosphate synthase pseudogene 2
FGF1 fibroblast growth factor 1 (acidic)
FILIP1L filamin A interacting protein 1-like
FLJ42627 uncharacterized LOC645644
FPR3 formyl peptide receptor 3
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GAS6 growth arrest-specific 6
GBX1 gastrulation brain homeobox 1
GCSAM germinal center-associated, signaling and motility
GLCE glucuronic acid epimerase
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPATCH11 G patch domain containing 11
GPR26 G protein-coupled receptor 26
GRAMD1B GRAM domain containing 1B
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRIP1 glutamate receptor interacting protein 1
GRSF1 G-rich RNA sequence binding factor 1
GTSE1 G-2 and S-phase expressed 1
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
HCG22 HLA complex group 22
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HJURP Holliday junction recognition protein
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DPB2 major histocompatibility complex, class II, DP beta 2 (pseudogene)
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HMMR hyaluronan-mediated motility receptor (RHAMM)
HOXD4 homeobox D4
HOXD8 homeobox D8
HPS3 Hermansky-Pudlak syndrome 3
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSDL2 hydroxysteroid dehydrogenase like 2
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL3RA interleukin 3 receptor, alpha (low affinity)
INSL6 insulin-like 6
INSM1 insulinoma-associated 1
IREB2 iron-responsive element binding protein 2
IRF4 interferon regulatory factor 4
IRF8 interferon regulatory factor 8
ITCH itchy E3 ubiquitin protein ligase
IYD iodotyrosine deiodinase
KBTBD8 kelch repeat and BTB (POZ) domain containing 8
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8
KCNK10 potassium channel, two pore domain subfamily K, member 10
KCNK13 potassium channel, two pore domain subfamily K, member 13
KCTD19 potassium channel tetramerization domain containing 19
KCTD5 potassium channel tetramerization domain containing 5
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0226L KIAA0226-like
KIAA1524 KIAA1524
KIF11 kinesin family member 11
KIF20B kinesin family member 20B
KIF23 kinesin family member 23
KIN Kin17 DNA and RNA binding protein
KITLG KIT ligand
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRTAP11-1 keratin associated protein 11-1
KRTAP8-1 keratin associated protein 8-1
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LHFPL1 lipoma HMGIC fusion partner-like 1
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LIMD1 LIM domains containing 1
LINC00158 long intergenic non-protein coding RNA 158
LINC00475 long intergenic non-protein coding RNA 475
LINC00515 long intergenic non-protein coding RNA 515
LMX1A LIM homeobox transcription factor 1, alpha
LOC100126784 uncharacterized LOC100126784
LOC389705 chromosome 4 open reading frame 27 pseudogene
LOC613037 nuclear pore complex interacting protein pseudogene
LOC646813 DEAH (Asp-Glu-Ala-His) box helicase 9 pseudogene
LRP1B low density lipoprotein receptor-related protein 1B
LRRC36 leucine rich repeat containing 36
MAGED4 melanoma antigen family D4
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene)
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MB myoglobin
MDFIC MyoD family inhibitor domain containing
MDM4 MDM4, p53 regulator
MELK maternal embryonic leucine zipper kinase
MEPE matrix extracellular phosphoglycoprotein
MGC12916 uncharacterized protein MGC12916
MINA MYC induced nuclear antigen
MIS12 MIS12 kinetochore complex component
MKX mohawk homeobox
MMP11 matrix metallopeptidase 11
MMP13 matrix metallopeptidase 13
MOB1B MOB kinase activator 1B
MOGAT1 monoacylglycerol O-acyltransferase 1
MPEG1 macrophage expressed 1
MRC1 mannose receptor, C type 1
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
MSL3 male-specific lethal 3 homolog (Drosophila)
MTMR1 myotubularin related protein 1
MTMR9 myotubularin related protein 9
MYO1E myosin IE
NAPSB napsin B aspartic peptidase, pseudogene
NCAPG non-SMC condensin I complex, subunit G
NCOA3 nuclear receptor coactivator 3
NDC80 NDC80 kinetochore complex component
NEK2 NIMA-related kinase 2
NES nestin
NEUROD4 neuronal differentiation 4
NHEG1 neuroblastoma highly expressed 1
NIN ninein (GSK3B interacting protein)
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2
NLRP7 NLR family, pyrin domain containing 7
NOX1 NADPH oxidase 1
NPC1 Niemann-Pick disease, type C1
NPY5R neuropeptide Y receptor Y5
NR5A1 nuclear receptor subfamily 5, group A, member 1
NRP1 neuropilin 1
NSL1 NSL1, MIS12 kinetochore complex component
NUPL2 nucleoporin like 2
OFD1 oral-facial-digital syndrome 1
OPN3 opsin 3
OR14C36 olfactory receptor, family 14, subfamily C, member 36
OR2M7 olfactory receptor, family 2, subfamily M, member 7
OR5AN1 olfactory receptor, family 5, subfamily AN, member 1
OR5K2 olfactory receptor, family 5, subfamily K, member 2
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
P3H2 prolyl 3-hydroxylase 2
PACSIN1 protein kinase C and casein kinase substrate in neurons 1
PARPBP PARP1 binding protein
PCDHGC3 protocadherin gamma subfamily C, 3
PCDHGC4 protocadherin gamma subfamily C, 4
PDGFB platelet-derived growth factor beta polypeptide
PDLIM3 PDZ and LIM domain 3
PFN4 profilin family, member 4
PGR progesterone receptor
PHACTR2 phosphatase and actin regulator 2
PHC3 polyhomeotic homolog 3 (Drosophila)
PHEX phosphate regulating endopeptidase homolog, X-linked
PIF1 PIF1 5'-to-3' DNA helicase
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCXD2 phosphatidylinositol-specific phospholipase C, X domain containing 2
PLP1 proteolipid protein 1
PLXNA4 plexin A4
PMEPA1 prostate transmembrane protein, androgen induced 1
POLB polymerase (DNA directed), beta
POLK polymerase (DNA directed) kappa
PPM1J protein phosphatase, Mg2+/Mn2+ dependent, 1J
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PRR25 proline rich 25
PSG3 pregnancy specific beta-1-glycoprotein 3
PTK2 protein tyrosine kinase 2
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPRE protein tyrosine phosphatase, receptor type, E
PTPRS protein tyrosine phosphatase, receptor type, S
RAB40B RAB40B, member RAS oncogene family
RAB41 RAB41, member RAS oncogene family
RABGAP1L RAB GTPase activating protein 1-like
RAD51AP1 RAD51 associated protein 1
RAP2A RAP2A, member of RAS oncogene family
RBL1 retinoblastoma-like 1
REC114 REC114 meiotic recombination protein
RECQL RecQ helicase-like
RFC3 replication factor C (activator 1) 3, 38kDa
RGN regucalcin
RGS7 regulator of G-protein signaling 7
RNASE6 ribonuclease, RNase A family, k6
RUFY3 RUN and FYVE domain containing 3
RUNX2 runt-related transcription factor 2
SAMHD1 SAM domain and HD domain 1
SCAMP5 secretory carrier membrane protein 5
SCARA5 scavenger receptor class A, member 5
SCARNA9 small Cajal body-specific RNA 9
SCN3B sodium channel, voltage gated, type III beta subunit
SCRN1 secernin 1
SCT secretin
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SEPT14 septin 14
SEPT2 septin 2
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SEZ6L seizure related 6 homolog (mouse)-like
SFT2D2 SFT2 domain containing 2
SGOL1 shugoshin-like 1 (S. pombe)
SH2B3 SH2B adaptor protein 3
SH2D7 SH2 domain containing 7
SH3BP4 SH3-domain binding protein 4
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1
SLC41A2 solute carrier family 41 (magnesium transporter), member 2
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC6A10P solute carrier family 6 (neurotransmitter transporter), member 10, pseudogene
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
SLC9C2 solute carrier family 9, member C2 (putative)
SLITRK5 SLIT and NTRK-like family, member 5
SMC6 structural maintenance of chromosomes 6
SMIM14 small integral membrane protein 14
SMOC1 SPARC related modular calcium binding 1
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SNORA79 small nucleolar RNA, H/ACA box 79
SNX18 sorting nexin 18
SNX31 sorting nexin 31
SOGA1 suppressor of glucose, autophagy associated 1
SPEM1 spermatid maturation 1
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SRPX sushi-repeat containing protein, X-linked
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STAMBPL1 STAM binding protein-like 1
STARD7 StAR-related lipid transfer (START) domain containing 7
STK38L serine/threonine kinase 38 like
STX18 syntaxin 18
STX7 syntaxin 7
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)
SULF2 sulfatase 2
SYCP2L synaptonemal complex protein 2-like
TAS2R10 taste receptor, type 2, member 10
TAS2R7 taste receptor, type 2, member 7
TATDN3 TatD DNase domain containing 3
TCF4 transcription factor 4
TENM4 teneurin transmembrane protein 4
TGFB2 transforming growth factor, beta 2
TGFBI transforming growth factor, beta-induced, 68kDa
THAP5 THAP domain containing 5
TIFA TRAF-interacting protein with forkhead-associated domain
TLDC2 TBC/LysM-associated domain containing 2
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMEM132B transmembrane protein 132B
TMEM19 transmembrane protein 19
TMEM207 transmembrane protein 207
TMEM8B transmembrane protein 8B
TMPO thymopoietin
TMX3 thioredoxin-related transmembrane protein 3
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNMD tenomodulin
TOP2A topoisomerase (DNA) II alpha 170kDa
TOX3 TOX high mobility group box family member 3
TRDMT1 tRNA aspartic acid methyltransferase 1
TTC13 tetratricopeptide repeat domain 13
TTC24 tetratricopeptide repeat domain 24
TTC39C tetratricopeptide repeat domain 39C
TTYH2 tweety family member 2
UBP1 upstream binding protein 1 (LBP-1a)
UBTFL1 upstream binding transcription factor, RNA polymerase I-like 1
UGCG UDP-glucose ceramide glucosyltransferase
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
USP1 ubiquitin specific peptidase 1
UST uronyl-2-sulfotransferase
UTF1 undifferentiated embryonic cell transcription factor 1
UVRAG UV radiation resistance associated
WDR66 WD repeat domain 66
WNT10A wingless-type MMTV integration site family, member 10A
ZBTB33 zinc finger and BTB domain containing 33
ZBTB8B zinc finger and BTB domain containing 8B
ZDHHC14 zinc finger, DHHC-type containing 14
ZDHHC17 zinc finger, DHHC-type containing 17
ZFAT zinc finger and AT hook domain containing
ZFAT-AS1 ZFAT antisense RNA 1
ZIC1 Zic family member 1
ZNF41 zinc finger protein 41
ZNF470 zinc finger protein 470
ZNF487 zinc finger protein 487
ZNF555 zinc finger protein 555
ZNF577 zinc finger protein 577
ZNF699 zinc finger protein 699
ZNF716 zinc finger protein 716
ZNF718 zinc finger protein 718
ZNF789 zinc finger protein 789
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase

low expression

Symbol Name
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)