Acute Myeloid Leukemia_LAML_TCGA-AB-2976-03A-01T-0734-13 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Acute Myeloid Leukemia_LAML (The Cancer Genome Atlas)
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400 genes with high or low expression in Acute Myeloid Leukemia_LAML_TCGA-AB-2976-03A-01T-0734-13 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ACRV1 acrosomal vesicle protein 1
ACTL6B actin-like 6B
ACTR6 ARP6 actin-related protein 6 homolog (yeast)
ACYP1 acylphosphatase 1, erythrocyte (common) type
ADGRA1 adhesion G protein-coupled receptor A1
ADGRG3 adhesion G protein-coupled receptor G3
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AGPAT4-IT1 AGPAT4 intronic transcript 1
AK3 adenylate kinase 3
AKR1C4 aldo-keto reductase family 1, member C4
ALCAM activated leukocyte cell adhesion molecule
ALG9 ALG9, alpha-1,2-mannosyltransferase
ALMS1 Alstrom syndrome protein 1
ALMS1P Alstrom syndrome 1 pseudogene
ANKRD16 ankyrin repeat domain 16
ANKRD36 ankyrin repeat domain 36
APOA5 apolipoprotein A-V
APOL4 apolipoprotein L, 4
ARHGAP11A Rho GTPase activating protein 11A
ARHGAP11B Rho GTPase activating protein 11B
ARHGAP15 Rho GTPase activating protein 15
ARHGEF35 Rho guanine nucleotide exchange factor (GEF) 35
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARL14 ADP-ribosylation factor-like 14
ASB13 ankyrin repeat and SOCS box containing 13
ASCC1 activating signal cointegrator 1 complex subunit 1
ASCL3 achaete-scute family bHLH transcription factor 3
ASPN asporin
ATAD3C ATPase family, AAA domain containing 3C
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
BAG2 BCL2-associated athanogene 2
BRCA1 breast cancer 1, early onset
C10ORF128 chromosome 10 open reading frame 128
C11ORF85 chromosome 11 open reading frame 85
C15ORF56 chromosome 15 open reading frame 56
C20ORF197 chromosome 20 open reading frame 197
C2ORF80 chromosome 2 open reading frame 80
C4ORF17 chromosome 4 open reading frame 17
C4ORF51 chromosome 4 open reading frame 51
C5ORF28 chromosome 5 open reading frame 28
C5ORF42 chromosome 5 open reading frame 42
C7ORF57 chromosome 7 open reading frame 57
CAB39L calcium binding protein 39-like
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CASC2 cancer susceptibility candidate 2 (non-protein coding)
CASQ2 calsequestrin 2 (cardiac muscle)
CBWD3 COBW domain containing 3
CCDC113 coiled-coil domain containing 113
CCDC125 coiled-coil domain containing 125
CCDC13 coiled-coil domain containing 13
CCDC138 coiled-coil domain containing 138
CCDC144A coiled-coil domain containing 144A
CCDC144B coiled-coil domain containing 144B (pseudogene)
CCDC150 coiled-coil domain containing 150
CCDC158 coiled-coil domain containing 158
CCDC170 coiled-coil domain containing 170
CCDC28A coiled-coil domain containing 28A
CCDC34 coiled-coil domain containing 34
CCDC87 coiled-coil domain containing 87
CD24 CD24 molecule
CD38 CD38 molecule
CDC25C cell division cycle 25C
CDC6 cell division cycle 6
CENPK centromere protein K
CENPQ centromere protein Q
CEP128 centrosomal protein 128kDa
CEP57L1 centrosomal protein 57kDa-like 1
CEP83 centrosomal protein 83kDa
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
CLLU1 chronic lymphocytic leukemia up-regulated 1
CLN5 ceroid-lipofuscinosis, neuronal 5
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNTNAP4 contactin associated protein-like 4
COL9A3 collagen, type IX, alpha 3
COX11 COX11 cytochrome c oxidase copper chaperone
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CST5 cystatin D
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CT45A3 cancer/testis antigen family 45, member A3
CT45A5 cancer/testis antigen family 45, member A5
CTAGE4 CTAGE family, member 4
CTAGE9 CTAGE family, member 9
CTSC cathepsin C
CXORF58 chromosome X open reading frame 58
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2
CYS1 cystin 1
DAPL1 death associated protein-like 1
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DBR1 debranching RNA lariats 1
DCSTAMP dendrocyte expressed seven transmembrane protein
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae)
DDX12P DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12, pseudogene
DIRC3 disrupted in renal carcinoma 3
DNA2 DNA replication helicase/nuclease 2
DNAH6 dynein, axonemal, heavy chain 6
DNAH7 dynein, axonemal, heavy chain 7
DOCK1 dedicator of cytokinesis 1
DPY19L2P2 DPY19L2 pseudogene 2
DPY19L2P4 DPY19L2 pseudogene 4
DSCR9 Down syndrome critical region 9 (non-protein coding)
DTWD2 DTW domain containing 2
DUSP5P1 dual specificity phosphatase 5 pseudogene 1
DYNLRB2 dynein, light chain, roadblock-type 2
DZANK1 double zinc ribbon and ankyrin repeat domains 1
E2F8 E2F transcription factor 8
EDN2 endothelin 2
EFCAB3 EF-hand calcium binding domain 3
EGOT eosinophil granule ontogeny transcript (non-protein coding)
EIF1B eukaryotic translation initiation factor 1B
ENOSF1 enolase superfamily member 1
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPDR1 ependymin related 1
EPGN epithelial mitogen
ERI1 exoribonuclease 1
ERICH5 glutamate-rich 5
EXOC6 exocyst complex component 6
EXOG endo/exonuclease (5'-3'), endonuclease G-like
EXTL2 exostosin-like glycosyltransferase 2
FADS1 fatty acid desaturase 1
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM106CP family with sequence similarity 106, member C, pseudogene
FAM161A family with sequence similarity 161, member A
FAM162A family with sequence similarity 162, member A
FAM170B family with sequence similarity 170, member B
FAM173B family with sequence similarity 173, member B
FAM196A family with sequence similarity 196, member A
FAM208B family with sequence similarity 208, member B
FAM47E family with sequence similarity 47, member E
FAM81B family with sequence similarity 81, member B
FAM92A1P2 family with sequence similarity 92, member A3
FANCD2 Fanconi anemia, complementation group D2
FKBP1AP1 FK506 binding protein 1A, 12kDa pseudogene 1
FKBP3 FK506 binding protein 3, 25kDa
FNDC9 fibronectin type III domain containing 9
FOXD4L5 forkhead box D4-like 5
FPGT fucose-1-phosphate guanylyltransferase
FRMD7 FERM domain containing 7
FSIP1 fibrous sheath interacting protein 1
GBP6 guanylate binding protein family, member 6
GLI2 GLI family zinc finger 2
GLMN glomulin, FKBP associated protein
GLRA1 glycine receptor, alpha 1
GLRA2 glycine receptor, alpha 2
GLRX2 glutaredoxin 2
GOLGA6L6 golgin A6 family-like 6
GOLGA8A golgin A8 family, member A
GOLGA8CP golgin A8 family, member C, pseudogene
GPR151 G protein-coupled receptor 151
GPR89B G protein-coupled receptor 89B
GRB10 growth factor receptor-bound protein 10
GREB1L growth regulation by estrogen in breast cancer-like
GRM5 glutamate receptor, metabotropic 5
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa
GTF2H2C GTF2H2 family member C
GTSF1 gametocyte specific factor 1
H2AFY2 H2A histone family, member Y2
HDHD2 haloacid dehalogenase-like hydrolase domain containing 2
HEATR6 HEAT repeat containing 6
HESX1 HESX homeobox 1
HHIPL2 HHIP-like 2
HIBADH 3-hydroxyisobutyrate dehydrogenase
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
HRH3 histamine receptor H3
HRNR hornerin
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IDI1 isopentenyl-diphosphate delta isomerase 1
IFT80 intraflagellar transport 80
IGSF10 immunoglobulin superfamily, member 10
IKZF4 IKAROS family zinc finger 4 (Eos)
IL1A interleukin 1, alpha
IL1RAP interleukin 1 receptor accessory protein
IL2RA interleukin 2 receptor, alpha
IMPACT impact RWD domain protein
INTS4P1 integrator complex subunit 4 pseudogene 1
IQCB1 IQ motif containing B1
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2
KCNS2 potassium voltage-gated channel, modifier subfamily S, member 2
KIAA0101 KIAA0101
KIAA0825 KIAA0825
KLHDC1 kelch domain containing 1
KLHL32 kelch-like family member 32
KNG1 kininogen 1
KRT83 keratin 83, type II
L2HGDH L-2-hydroxyglutarate dehydrogenase
LALBA lactalbumin, alpha-
LAPTM4B lysosomal protein transmembrane 4 beta
LCT lactase
LEKR1 leucine, glutamate and lysine rich 1
LGALS14 lectin, galactoside-binding, soluble, 14
LIMA1 LIM domain and actin binding 1
LINC00238 long intergenic non-protein coding RNA 238
LINC00515 long intergenic non-protein coding RNA 515
LINS lines homolog (Drosophila)
LOC100130093 uncharacterized LOC100130093
LOC148696 uncharacterized LOC148696
LOC284009 uncharacterized LOC284009
LOC285847 uncharacterized LOC285847
LOC440173 uncharacterized LOC440173
LOC730668 dynein heavy chain -like pseudogene
LRRN3 leucine rich repeat neuronal 3
LRTM2 leucine-rich repeats and transmembrane domains 2
LYRM1 LYR motif containing 1
MAGED4 melanoma antigen family D4
MASTL microtubule associated serine/threonine kinase-like
MBL2 mannose-binding lectin (protein C) 2, soluble
MCTS2P malignant T cell amplified sequence 2, pseudogene
METTL15 methyltransferase like 15
METTL8 methyltransferase like 8
MIR155HG MIR155 host gene
MLH3 mutL homolog 3
MORN4 MORN repeat containing 4
MPZL2 myelin protein zero-like 2
MSL3P1 male-specific lethal 3 homolog (Drosophila) pseudogene 1
MSMO1 methylsterol monooxygenase 1
MTFMT mitochondrial methionyl-tRNA formyltransferase
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2
NANOG Nanog homeobox
NAT8 N-acetyltransferase 8 (GCN5-related, putative)
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NIPAL2 NIPA-like domain containing 2
NIT2 nitrilase family, member 2
NLK nemo-like kinase
NLRP2 NLR family, pyrin domain containing 2
NME7 NME/NM23 family member 7
NPSR1 neuropeptide S receptor 1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUPL2 nucleoporin like 2
OR13C8 olfactory receptor, family 13, subfamily C, member 8
OR2A1 olfactory receptor, family 2, subfamily A, member 1
OR2A12 olfactory receptor, family 2, subfamily A, member 12
OR2A14 olfactory receptor, family 2, subfamily A, member 14
OR2A2 olfactory receptor, family 2, subfamily A, member 2
OR2A4 olfactory receptor, family 2, subfamily A, member 4
OR2A5 olfactory receptor, family 2, subfamily A, member 5
OR2A7 olfactory receptor, family 2, subfamily A, member 7
OR2A9P olfactory receptor, family 2, subfamily A, member 9 pseudogene
OR2B2 olfactory receptor, family 2, subfamily B, member 2
OR2T10 olfactory receptor, family 2, subfamily T, member 10
OR6C2 olfactory receptor, family 6, subfamily C, member 2
OR6C70 olfactory receptor, family 6, subfamily C, member 70
ORC5 origin recognition complex, subunit 5
PBX3 pre-B-cell leukemia homeobox 3
PCDH19 protocadherin 19
PDGFD platelet derived growth factor D
PGBD4 piggyBac transposable element derived 4
PHF21A PHD finger protein 21A
PIGF phosphatidylinositol glycan anchor biosynthesis, class F
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PKD1L3 polycystic kidney disease 1-like 3
PLS1 plastin 1
PMEL premelanosome protein
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POLI polymerase (DNA directed) iota
PON1 paraoxonase 1
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRDM16 PR domain containing 16
PRDM2 PR domain containing 2, with ZNF domain
PRORSD1P prolyl-tRNA synthetase associated domain containing 1, pseudogene
PRR34 proline rich 34
PSPH phosphoserine phosphatase
PTBP3 polypyrimidine tract binding protein 3
RAB23 RAB23, member RAS oncogene family
RAB38 RAB38, member RAS oncogene family
RAB40A RAB40A, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RAD54L RAD54-like (S. cerevisiae)
RANBP17 RAN binding protein 17
RARB retinoic acid receptor, beta
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBBP8 retinoblastoma binding protein 8
RCAN2 regulator of calcineurin 2
REN renin
RFC5 replication factor C (activator 1) 5, 36.5kDa
RFTN1 raftlin, lipid raft linker 1
RLBP1 retinaldehyde binding protein 1
S100A1 S100 calcium binding protein A1
S100Z S100 calcium binding protein Z
SAA2 serum amyloid A2
SAGE1 sarcoma antigen 1
SASS6 spindle assembly 6 homolog (C. elegans)
SCG5 secretogranin V
SCN2A sodium channel, voltage gated, type II alpha subunit
SCRT1 scratch family zinc finger 1
SDHAP3 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3
SEMG1 semenogelin I
SEPT7P2 septin 7 pseudogene 2
SESN1 sestrin 1
SETD6 SET domain containing 6
SETDB2 SET domain, bifurcated 2
SFTA2 surfactant associated 2
SH2D1A SH2 domain containing 1A
SIGLEC6 sialic acid binding Ig-like lectin 6
SKIDA1 SKI/DACH domain containing 1
SLC22A24 solute carrier family 22, member 24
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
SMC4 structural maintenance of chromosomes 4
SNAP47 synaptosomal-associated protein, 47kDa
SNHG12 small nucleolar RNA host gene 12
SNHG3 small nucleolar RNA host gene 3
SNORA16B small nucleolar RNA, H/ACA box 16B
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2
SPACA5 sperm acrosome associated 5
SPAG1 sperm associated antigen 1
SPATA31A1 SPATA31 subfamily A, member 1
SPATS2 spermatogenesis associated, serine-rich 2
SPICE1 spindle and centriole associated protein 1
STARD13 StAR-related lipid transfer (START) domain containing 13
STON1 stonin 1
STOX1 storkhead box 1
STX16 syntaxin 16
STX19 syntaxin 19
STXBP4 syntaxin binding protein 4
STXBP5 syntaxin binding protein 5 (tomosyn)
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4
SUSD1 sushi domain containing 1
SVIL supervillin
SVIP small VCP/p97-interacting protein
SYPL1 synaptophysin-like 1
SYTL4 synaptotagmin-like 4
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TBC1D22B TBC1 domain family, member 22B
TCEAL1 transcription elongation factor A (SII)-like 1
TGDS TDP-glucose 4,6-dehydratase
TIPIN TIMELESS interacting protein
TMC1 transmembrane channel-like 1
TMEM217 transmembrane protein 217
TMEM242 transmembrane protein 242
TMEM5 transmembrane protein 5
TMEM97 transmembrane protein 97
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TNP2 transition protein 2 (during histone to protamine replacement)
TOM1L1 target of myb1 (chicken)-like 1
TREML2 triggering receptor expressed on myeloid cells-like 2
TRIM15 tripartite motif containing 15
TRIM16L tripartite motif containing 16-like
TRIM37 tripartite motif containing 37
TRIM66 tripartite motif containing 66
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
TSPYL6 TSPY-like 6
TTC23L tetratricopeptide repeat domain 23-like
TTC30A tetratricopeptide repeat domain 30A
TTC30B tetratricopeptide repeat domain 30B
TTF2 transcription termination factor, RNA polymerase II
TTPA tocopherol (alpha) transfer protein
TTTY9B testis-specific transcript, Y-linked 9B (non-protein coding)
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1
ULK4P2 ULK4 pseudogene 2
ULK4P3 ULK4 pseudogene 3
USP6NL USP6 N-terminal like
UXS1 UDP-glucuronate decarboxylase 1
VSIG10 V-set and immunoglobulin domain containing 10
VSTM4 V-set and transmembrane domain containing 4
WDR5B WD repeat domain 5B
XKRX XK, Kell blood group complex subunit-related, X-linked
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRRA1 X-ray radiation resistance associated 1
YAE1D1 Yae1 domain containing 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZDHHC13 zinc finger, DHHC-type containing 13
ZDHHC15 zinc finger, DHHC-type containing 15
ZFP2 ZFP2 zinc finger protein
ZFP62 ZFP62 zinc finger protein
ZFP90 ZFP90 zinc finger protein
ZNF175 zinc finger protein 175
ZNF354B zinc finger protein 354B
ZNF41 zinc finger protein 41
ZNF43 zinc finger protein 43
ZNF442 zinc finger protein 442
ZNF470 zinc finger protein 470
ZNF546 zinc finger protein 546
ZNF674 zinc finger protein 674
ZNF682 zinc finger protein 682
ZNF695 zinc finger protein 695
ZNF823 zinc finger protein 823
ZNF826P zinc finger protein 826, pseudogene
ZPBP zona pellucida binding protein
ZSCAN20 zinc finger and SCAN domain containing 20

low expression

Symbol Name
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6
SP140L SP140 nuclear body protein-like
SRSF8 serine/arginine-rich splicing factor 8