Acute Myeloid Leukemia_LAML_TCGA-AB-2988-03B-01T-0748-13 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Acute Myeloid Leukemia_LAML (The Cancer Genome Atlas)
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302 genes with high or low expression in Acute Myeloid Leukemia_LAML_TCGA-AB-2988-03B-01T-0748-13 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14
ADGRB1 adhesion G protein-coupled receptor B1
ADGRG1 adhesion G protein-coupled receptor G1
ADHFE1 alcohol dehydrogenase, iron containing, 1
ADK adenosine kinase
AGBL2 ATP/GTP binding protein-like 2
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AGPAT4-IT1 AGPAT4 intronic transcript 1
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9
AIF1L allograft inflammatory factor 1-like
AMN amnion associated transmembrane protein
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANO7 anoctamin 7
APOA5 apolipoprotein A-V
APTX aprataxin
AQP6 aquaporin 6, kidney specific
ARHGAP11B Rho GTPase activating protein 11B
ARHGAP18 Rho GTPase activating protein 18
ARHGEF35 Rho guanine nucleotide exchange factor (GEF) 35
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARMC2 armadillo repeat containing 2
ARMC3 armadillo repeat containing 3
ARRDC4 arrestin domain containing 4
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BBS12 Bardet-Biedl syndrome 12
BBS2 Bardet-Biedl syndrome 2
BRDT bromodomain, testis-specific
BTBD8 BTB (POZ) domain containing 8
C10ORF128 chromosome 10 open reading frame 128
C11ORF74 chromosome 11 open reading frame 74
C14ORF178 chromosome 14 open reading frame 178
C1ORF220 chromosome 1 open reading frame 220
C20ORF166-AS1 C20orf166 antisense RNA 1
C2ORF49 chromosome 2 open reading frame 49
C2ORF80 chromosome 2 open reading frame 80
C4ORF32 chromosome 4 open reading frame 32
C9ORF139 chromosome 9 open reading frame 139
CAB39L calcium binding protein 39-like
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CBWD5 COBW domain containing 5
CCDC113 coiled-coil domain containing 113
CCDC121 coiled-coil domain containing 121
CCDC180 coiled-coil domain containing 180
CCDC24 coiled-coil domain containing 24
CCDC70 coiled-coil domain containing 70
CD80 CD80 molecule
CDC16 cell division cycle 16
CDRT1 CMT1A duplicated region transcript 1
CDX1 caudal type homeobox 1
CEP89 centrosomal protein 89kDa
CFAP20 cilia and flagella associated protein 20
CFAP52 cilia and flagella associated protein 52
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
CLK2P1 CDC-like kinase 2, pseudogene 1
CLYBL citrate lyase beta like
COMMD3 COMM domain containing 3
COQ9 coenzyme Q9
CT45A3 cancer/testis antigen family 45, member A3
CTAGE4 CTAGE family, member 4
CTAGE9 CTAGE family, member 9
CTSC cathepsin C
CXORF38 chromosome X open reading frame 38
CYSLTR2 cysteinyl leukotriene receptor 2
DCDC1 doublecortin domain containing 1
DCSTAMP dendrocyte expressed seven transmembrane protein
DEPDC4 DEP domain containing 4
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DKK4 dickkopf WNT signaling pathway inhibitor 4
DMTF1 cyclin D binding myb-like transcription factor 1
DNAH3 dynein, axonemal, heavy chain 3
DNAI2 dynein, axonemal, intermediate chain 2
DOCK1 dedicator of cytokinesis 1
DPP4 dipeptidyl-peptidase 4
DSCR9 Down syndrome critical region 9 (non-protein coding)
DZANK1 double zinc ribbon and ankyrin repeat domains 1
E2F5 E2F transcription factor 5, p130-binding
EIF1B eukaryotic translation initiation factor 1B
EIF3IP1 eukaryotic translation initiation factor 3, subunit I pseudogene 1
ENOSF1 enolase superfamily member 1
ETFDH electron-transferring-flavoprotein dehydrogenase
EXOC1 exocyst complex component 1
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM179A family with sequence similarity 179, member A
FAM185A family with sequence similarity 185, member A
FAM196A family with sequence similarity 196, member A
FAM92A1 family with sequence similarity 92, member A1
FAM9B family with sequence similarity 9, member B
FASTKD1 FAST kinase domains 1
FBXO34 F-box protein 34
FBXW10 F-box and WD repeat domain containing 10
FMO6P flavin containing monooxygenase 6 pseudogene
FUBP1 far upstream element (FUSE) binding protein 1
GAL3ST2 galactose-3-O-sulfotransferase 2
GALNT4 polypeptide N-acetylgalactosaminyltransferase 4
GLI2 GLI family zinc finger 2
GNG8 guanine nucleotide binding protein (G protein), gamma 8
GOLGA8B golgin A8 family, member B
GOLGA8DP golgin A8 family, member D, pseudogene
GPR89B G protein-coupled receptor 89B
GRIA3 glutamate receptor, ionotropic, AMPA 3
GSTA1 glutathione S-transferase alpha 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY2EP guanylate cyclase 2E, pseudogene
HIBCH 3-hydroxyisobutyryl-CoA hydrolase
HIP1 huntingtin interacting protein 1
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HSP90AB2P heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene
HTATSF1 HIV-1 Tat specific factor 1
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
IFNA10 interferon, alpha 10
IFT57 intraflagellar transport 57
IFT80 intraflagellar transport 80
IFT88 intraflagellar transport 88
IGSF10 immunoglobulin superfamily, member 10
IL12A interleukin 12A
IL1RL2 interleukin 1 receptor-like 2
IL2RA interleukin 2 receptor, alpha
ILDR2 immunoglobulin-like domain containing receptor 2
KBTBD8 kelch repeat and BTB (POZ) domain containing 8
KCTD9 potassium channel tetramerization domain containing 9
KIAA0907 KIAA0907
KIAA1407 KIAA1407
KLHL12 kelch-like family member 12
KLHL9 kelch-like family member 9
KY kyphoscoliosis peptidase
LACE1 lactation elevated 1
LCT lactase
LDLRAD2 low density lipoprotein receptor class A domain containing 2
LGALS7 lectin, galactoside-binding, soluble, 7
LINC00652 long intergenic non-protein coding RNA 652
LOC100133050 glucuronidase, beta pseudogene
LOC100270804 uncharacterized LOC100270804
LOC728613 programmed cell death 6 pseudogene
LRRC27 leucine rich repeat containing 27
LRRC6 leucine rich repeat containing 6
LURAP1 leucine rich adaptor protein 1
LYRM1 LYR motif containing 1
MAATS1 MYCBP-associated, testis expressed 1
MAPK15 mitogen-activated protein kinase 15
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MATN4 matrilin 4
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha)
MED7 mediator complex subunit 7
MIR1-1HG MIR1-1 host gene
MIR155HG MIR155 host gene
MKKS McKusick-Kaufman syndrome
MKRN3 makorin ring finger protein 3
MLH1 mutL homolog 1
MNS1 meiosis-specific nuclear structural 1
MRPS14 mitochondrial ribosomal protein S14
MSL3P1 male-specific lethal 3 homolog (Drosophila) pseudogene 1
MTG1 mitochondrial ribosome-associated GTPase 1
N4BP3 NEDD4 binding protein 3
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit
NEK11 NIMA-related kinase 11
NEK5 NIMA-related kinase 5
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NKAP NFKB activating protein
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRAP nebulin-related anchoring protein
NRG4 neuregulin 4
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1
NSUN5P2 NOP2/Sun domain family, member 5 pseudogene 2
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OCM2 oncomodulin 2
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OR2A1 olfactory receptor, family 2, subfamily A, member 1
OR2A4 olfactory receptor, family 2, subfamily A, member 4
OR2A7 olfactory receptor, family 2, subfamily A, member 7
OR5A2 olfactory receptor, family 5, subfamily A, member 2
PABPC1L poly(A) binding protein, cytoplasmic 1-like
PBX3 pre-B-cell leukemia homeobox 3
PDCD6 programmed cell death 6
PGBD4 piggyBac transposable element derived 4
PGK2 phosphoglycerate kinase 2
PIGF phosphatidylinositol glycan anchor biosynthesis, class F
PKD1L3 polycystic kidney disease 1-like 3
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLS1 plastin 1
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POM121L8P POM121 transmembrane nucleoporin-like 8 pseudogene
POM121L9P POM121 transmembrane nucleoporin-like 9, pseudogene
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PRMT9 protein arginine methyltransferase 9
PRORSD1P prolyl-tRNA synthetase associated domain containing 1, pseudogene
PRSS21 protease, serine, 21 (testisin)
PRSS41 protease, serine, 41
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMG3 proteasome (prosome, macropain) assembly chaperone 3
PTCD2 pentatricopeptide repeat domain 2
PTPRVP protein tyrosine phosphatase, receptor type, V, pseudogene
QPRT quinolinate phosphoribosyltransferase
RAB38 RAB38, member RAS oncogene family
RAB40A RAB40A, member RAS oncogene family
RANBP6 RAN binding protein 6
RARB retinoic acid receptor, beta
RBM45 RNA binding motif protein 45
RDM1 RAD52 motif containing 1
REN renin
RHBDL3 rhomboid, veinlet-like 3 (Drosophila)
RHEBL1 Ras homolog enriched in brain like 1
RIBC1 RIB43A domain with coiled-coils 1
RIMBP2 RIMS binding protein 2
RP1L1 retinitis pigmentosa 1-like 1
RSRP1 arginine/serine-rich protein 1
RYR1 ryanodine receptor 1 (skeletal)
S100A1 S100 calcium binding protein A1
S100Z S100 calcium binding protein Z
SAGE1 sarcoma antigen 1
SCN4A sodium channel, voltage gated, type IV alpha subunit
SDHAP3 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3
SDSL serine dehydratase-like
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEPT14 septin 14
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SH3D21 SH3 domain containing 21
SKIDA1 SKI/DACH domain containing 1
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SLCO1B7 solute carrier organic anion transporter family, member 1B7 (non-functional)
SLX4IP SLX4 interacting protein
SMC4 structural maintenance of chromosomes 4
SNHG4 small nucleolar RNA host gene 4
SNORA74A small nucleolar RNA, H/ACA box 74A
SNX31 sorting nexin 31
SOCS4 suppressor of cytokine signaling 4
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2
SORT1 sortilin 1
SPAG6 sperm associated antigen 6
SPAG8 sperm associated antigen 8
SPATA12 spermatogenesis associated 12
SPATA24 spermatogenesis associated 24
SPESP1 sperm equatorial segment protein 1
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SVIL supervillin
TAL2 T-cell acute lymphocytic leukemia 2
TBC1D15 TBC1 domain family, member 15
TBC1D29 TBC1 domain family, member 29
TBCC tubulin folding cofactor C
TDRD1 tudor domain containing 1
TEX13B testis expressed 13B
TFB1M transcription factor B1, mitochondrial
TIGD1 tigger transposable element derived 1
TMEM186 transmembrane protein 186
TMEM217 transmembrane protein 217
TMEM38B transmembrane protein 38B
TMEM60 transmembrane protein 60
TMPRSS7 transmembrane protease, serine 7
TOM1L1 target of myb1 (chicken)-like 1
TREML2 triggering receptor expressed on myeloid cells-like 2
TRIM15 tripartite motif containing 15
TRIM16 tripartite motif containing 16
TRIM16L tripartite motif containing 16-like
TRIM50 tripartite motif containing 50
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
TTC14 tetratricopeptide repeat domain 14
TTC24 tetratricopeptide repeat domain 24
TTC30B tetratricopeptide repeat domain 30B
TTC5 tetratricopeptide repeat domain 5
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
ULK4P2 ULK4 pseudogene 2
ULK4P3 ULK4 pseudogene 3
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
VSIG10 V-set and immunoglobulin domain containing 10
WDR5B WD repeat domain 5B
WDR92 WD repeat domain 92
WFDC10B WAP four-disulfide core domain 10B
ZBTB26 zinc finger and BTB domain containing 26
ZDHHC15 zinc finger, DHHC-type containing 15
ZNF133 zinc finger protein 133
ZNF286A zinc finger protein 286A
ZNF324 zinc finger protein 324
ZNF474 zinc finger protein 474
ZNF584 zinc finger protein 584
ZNF589 zinc finger protein 589
ZNF70 zinc finger protein 70
ZNF705D zinc finger protein 705D
ZNF830 zinc finger protein 830

low expression

Symbol Name
CHD3 chromodomain helicase DNA binding protein 3
CRY1 cryptochrome circadian clock 1
ECI2 enoyl-CoA delta isomerase 2
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
RNF130 ring finger protein 130
SRSF8 serine/arginine-rich splicing factor 8