Acute Myelomonocytic Leukemia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A pediatric acute myeloid leukemia involving both myeloid and monocytoid precursors. At least 20% of non-erythroid cells are of monocytic origin. (Human Phenotype Ontology, HP_0004820)
External Link https://www.disgenet.org/browser/0/1/0/C0023479
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Genes

98 genes associated with the disease Acute Myelomonocytic Leukemia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACHE acetylcholinesterase (Yt blood group)
ADIPOQ adiponectin, C1Q and collagen domain containing
AHR aryl hydrocarbon receptor
ALK anaplastic lymphoma receptor tyrosine kinase
ATM ATM serine/threonine kinase
BCR breakpoint cluster region
CASC5 cancer susceptibility candidate 5
CBFB core-binding factor, beta subunit
CCND3 cyclin D3
CD14 CD14 molecule
CD19 CD19 molecule
CD34 CD34 molecule
CD38 CD38 molecule
CD6 CD6 molecule
CDC25A cell division cycle 25A
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CHRM3 cholinergic receptor, muscarinic 3
CREBBP CREB binding protein
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CXCR4 chemokine (C-X-C motif) receptor 4
CYBB cytochrome b-245, beta polypeptide
DERL1 derlin 1
DHFR dihydrofolate reductase
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EIF4E eukaryotic translation initiation factor 4E
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EVPL envoplakin
FANCB Fanconi anemia, complementation group B
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FGFR1 fibroblast growth factor receptor 1
FLNA filamin A, alpha
FLT3 fms-related tyrosine kinase 3
FN1 fibronectin 1
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GATA2 GATA binding protein 2
HLA-DMB major histocompatibility complex, class II, DM beta
HOXA9 homeobox A9
HOXC13 homeobox C13
HOXC5 homeobox C5
HOXD11 homeobox D11
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPB3 heat shock 27kDa protein 3
IGF1 insulin-like growth factor 1 (somatomedin C)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KAT6A K(lysine) acetyltransferase 6A
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KMT2A lysine (K)-specific methyltransferase 2A
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
MAPK1 mitogen-activated protein kinase 1
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP9 matrix metallopeptidase 9
MNX1 motor neuron and pancreas homeobox 1
MPO myeloperoxidase
MUC1 mucin 1, cell surface associated
MYB v-myb avian myeloblastosis viral oncogene homolog
MYH11 myosin, heavy chain 11, smooth muscle
NCF1 neutrophil cytosolic factor 1
NCOA2 nuclear receptor coactivator 2
NOTCH1 notch 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NSD1 nuclear receptor binding SET domain protein 1
NUP98 nucleoporin 98kDa
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PCBP4 poly(rC) binding protein 4
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLSCR1 phospholipid scramblase 1
PRDM16 PR domain containing 16
PRG4 proteoglycan 4
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RANBP2 RAN binding protein 2
RET ret proto-oncogene
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
RUNX2 runt-related transcription factor 2
SAMD9L sterile alpha motif domain containing 9-like
SEPT6 septin 6
SEPT9 septin 9
SETBP1 SET binding protein 1
SIRPA signal-regulatory protein alpha
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
TFRC transferrin receptor
TH tyrosine hydroxylase
TMEM132D transmembrane protein 132D
TNF tumor necrosis factor
TP53 tumor protein p53
WDR76 WD repeat domain 76