Acute Pancreatitis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0001339
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Genes

415 genes associated with the disease Acute Pancreatitis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACR acrosin
ACTB actin, beta
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM2 adrenomedullin 2
AGER advanced glycosylation end product-specific receptor
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHCY adenosylhomocysteinase
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AHSG alpha-2-HS-glycoprotein
AIM2 absent in melanoma 2
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANXA2 annexin A2
ANXA3 annexin A3
APCS amyloid P component, serum
APOA1 apolipoprotein A-I
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOC2 apolipoprotein C-II
APOC3 apolipoprotein C-III
APOE apolipoprotein E
AQP5 aquaporin 5
AQP8 aquaporin 8
ARFRP1 ADP-ribosylation factor related protein 1
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ASPG asparaginase
ASRGL1 asparaginase like 1
ATG7 autophagy related 7
AVP arginine vasopressin
AZIN2 antizyme inhibitor 2
BCL2 B-cell CLL/lymphoma 2
BCL3 B-cell CLL/lymphoma 3
BECN1 beclin 1, autophagy related
BET1 Bet1 golgi vesicular membrane trafficking protein
BIRC5 baculoviral IAP repeat containing 5
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
BTBD8 BTB (POZ) domain containing 8
BTC betacellulin
CALCA calcitonin-related polypeptide alpha
CAPN1 calpain 1, (mu/I) large subunit
CARD9 caspase recruitment domain family, member 9
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAT catalase
CBS cystathionine-beta-synthase
CCDC91 coiled-coil domain containing 91
CCK cholecystokinin
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCR2 chemokine (C-C motif) receptor 2
CD14 CD14 molecule
CD19 CD19 molecule
CD24 CD24 molecule
CD274 CD274 molecule
CD34 CD34 molecule
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase)
CEL carboxyl ester lipase
CELA3B chymotrypsin-like elastase family, member 3B
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLDN2 claudin 2
CLDN4 claudin 4
CNPY2 canopy FGF signaling regulator 2
CNR2 cannabinoid receptor 2 (macrophage)
COL25A1 collagen, type XXV, alpha 1
COX2
CPB1 carboxypeptidase B1 (tissue)
CPB2 carboxypeptidase B2 (plasma)
CPTP ceramide-1-phosphate transfer protein
CRH corticotropin releasing hormone
CRISP1 cysteine-rich secretory protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRP C-reactive protein, pentraxin-related
CSF3 colony stimulating factor 3 (granulocyte)
CST3 cystatin C
CTH cystathionine gamma-lyase
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTRC chymotrypsin C (caldecrin)
CTSB cathepsin B
CTSG cathepsin G
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DCTN4 dynactin 4 (p62)
DDIT3 DNA-damage-inducible transcript 3
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DEFB1 defensin, beta 1
DEFB104A defensin, beta 104A
DEFB104B defensin, beta 104B
DEFB4A defensin, beta 4A
DEFB4B defensin, beta 4B
DNER delta/notch-like EGF repeat containing
DPP4 dipeptidyl-peptidase 4
DSPP dentin sialophosphoprotein
DUSP1 dual specificity phosphatase 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELANE elastase, neutrophil expressed
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPHB1 EPH receptor B1
EPHB2 EPH receptor B2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
ERN1 endoplasmic reticulum to nucleus signaling 1
ERO1A endoplasmic reticulum oxidoreductase 1 alpha
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETV5 ets variant 5
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
FABP2 fatty acid binding protein 2, intestinal
FAM129A family with sequence similarity 129, member A
FAS Fas cell surface death receptor
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FGF21 fibroblast growth factor 21
FGFR1 fibroblast growth factor receptor 1
FGL2 fibrinogen-like 2
FN1 fibronectin 1
FOXF1 forkhead box F1
FUT2 fucosyltransferase 2 (secretor status included)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GADL1 glutamate decarboxylase-like 1
GAL galanin/GMAP prepropeptide
GALR2 galanin receptor 2
GALR3 galanin receptor 3
GCG glucagon
GDF15 growth differentiation factor 15
GFER growth factor, augmenter of liver regeneration
GGTLC1 gamma-glutamyltransferase light chain 1
GH1 growth hormone 1
GHRL ghrelin/obestatin prepropeptide
GLI2 GLI family zinc finger 2
GLP1R glucagon-like peptide 1 receptor
GOLGA6A golgin A6 family, member A
GORASP1 golgi reassembly stacking protein 1, 65kDa
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GP2 glycoprotein 2 (zymogen granule membrane)
GPBAR1 G protein-coupled bile acid receptor 1
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
GPRC6A G protein-coupled receptor, class C, group 6, member A
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRAP2 GRB2-related adaptor protein 2
GSR glutathione reductase
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
HAVCR2 hepatitis A virus cellular receptor 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGB1 high mobility group box 1
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HMOX1 heme oxygenase 1
HPSE heparanase
HRG histidine-rich glycoprotein
HSF1 heat shock transcription factor 1
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPA2 heat shock 70kDa protein 2
HSPA4 heat shock 70kDa protein 4
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPB3 heat shock 27kDa protein 3
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IL10 interleukin 10
IL12B interleukin 12B
IL13 interleukin 13
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL21 interleukin 21
IL2RA interleukin 2 receptor, alpha
IL33 interleukin 33
IL4 interleukin 4
IL6 interleukin 6
IL7R interleukin 7 receptor
INTU inturned planar cell polarity protein
IP6K1 inositol hexakisphosphate kinase 1
ISG20 interferon stimulated exonuclease gene 20kDa
ISYNA1 inositol-3-phosphate synthase 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JAK2 Janus kinase 2
KDR kinase insert domain receptor
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KL klotho
KLF2 Kruppel-like factor 2
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KMT2D lysine (K)-specific methyltransferase 2D
KNG1 kininogen 1
KRT5 keratin 5, type II
LCN2 lipocalin 2
LEP leptin
LGALS3 lectin, galactoside-binding, soluble, 3
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LMF1 lipase maturation factor 1
LMNA lamin A/C
LOC102724197 inactive gamma-glutamyltranspeptidase 2-like
LOC102724560 cystathionine beta-synthase
LPA lipoprotein, Lp(a)
LPL lipoprotein lipase
LTA lymphotoxin alpha
LTB4R leukotriene B4 receptor
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MANF mesencephalic astrocyte-derived neurotrophic factor
MAP2K3 mitogen-activated protein kinase kinase 3
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MARCH2 membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
MARVELD2 MARVEL domain containing 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MDK midkine (neurite growth-promoting factor 2)
MEFV Mediterranean fever
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MLKL mixed lineage kinase domain-like
MLN motilin
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MOK MOK protein kinase
MORC4 MORC family CW-type zinc finger 4
MPO myeloperoxidase
MPRIP myosin phosphatase Rho interacting protein
MTAP methylthioadenosine phosphorylase
MTNR1B melatonin receptor 1B
MYO9B myosin IXB
NFE2L2 nuclear factor, erythroid 2-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NINL ninein-like
NLRP3 NLR family, pyrin domain containing 3
NOS2 nitric oxide synthase 2, inducible
NPPA natriuretic peptide A
NPY neuropeptide Y
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae)
NTS neurotensin
NUP62 nucleoporin 62kDa
OCLN occludin
OLFM1 olfactomedin 1
OR10A4 olfactory receptor, family 10, subfamily A, member 4
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAEP progestagen-associated endometrial protein
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARD3 par-3 family cell polarity regulator
PDCD1 programmed cell death 1
PIAS3 protein inhibitor of activated STAT, 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLG plasminogen
PNLIP pancreatic lipase
PNLIPRP2 pancreatic lipase-related protein 2
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
PON1 paraoxonase 1
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPID peptidylprolyl isomerase D
PPIF peptidylprolyl isomerase F
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPY pancreatic polypeptide
PRKCD protein kinase C, delta
PRKD1 protein kinase D1
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROCR protein C receptor, endothelial
PRSS1 protease, serine, 1 (trypsin 1)
PRSS2 protease, serine, 2 (trypsin 2)
PRSS3 protease, serine, 3
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTHLH parathyroid hormone-like hormone
PTK2B protein tyrosine kinase 2 beta
PTPA protein phosphatase 2 phosphatase activator
PTPRC protein tyrosine phosphatase, receptor type, C
PTX3 pentraxin 3, long
PYY peptide YY
RAB21 RAB21, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAB7B RAB7B, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RACK1 receptor for activated C kinase 1
RALBP1 ralA binding protein 1
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBP4 retinol binding protein 4, plasma
RCAN1 regulator of calcineurin 1
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
REG3A regenerating islet-derived 3 alpha
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RERE arginine-glutamic acid dipeptide (RE) repeats
RETN resistin
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK2 receptor-interacting serine-threonine kinase 2
RIPK3 receptor-interacting serine-threonine kinase 3
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RTL1 retrotransposon-like 1
RUNX3 runt-related transcription factor 3
S100A12 S100 calcium binding protein A12
S100A9 S100 calcium binding protein A9
SARAF store-operated calcium entry-associated regulatory factor
SCT secretin
SELE selectin E
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SETMAR SET domain and mariner transposase fusion gene
SFTPD surfactant protein D
SGSM3 small G protein signaling modulator 3
SH2D1A SH2 domain containing 1A
SIRT1 sirtuin 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SMAD2 SMAD family member 2
SMAD7 SMAD family member 7
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNAP25 synaptosomal-associated protein, 25kDa
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
SOX9 SRY (sex determining region Y)-box 9
SPHK2 sphingosine kinase 2
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SQSTM1 sequestosome 1
SRA1 steroid receptor RNA activator 1
SSRP1 structure specific recognition protein 1
SST somatostatin
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIM1 stromal interaction molecule 1
STING1 stimulator of interferon response cGAMP interactor 1
STX2 syntaxin 2
SYT1 synaptotagmin I
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAC1 tachykinin, precursor 1
TCF3 transcription factor 3
TFAM transcription factor A, mitochondrial
TFEB transcription factor EB
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
THPO thrombopoietin
TICAM1 toll-like receptor adaptor molecule 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TLR9 toll-like receptor 9
TM7SF2 transmembrane 7 superfamily member 2
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNIP2 TNFAIP3 interacting protein 2
TNMD tenomodulin
TP53 tumor protein p53
TP53INP1 tumor protein p53 inducible nuclear protein 1
TRAF3 TNF receptor-associated factor 3
TREM1 triggering receptor expressed on myeloid cells 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TYMS thymidylate synthetase
UCN2 urocortin 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UMOD uromodulin
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
UROD uroporphyrinogen decarboxylase
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIP vasoactive intestinal peptide
VMP1 vacuole membrane protein 1
WNK1 WNK lysine deficient protein kinase 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YAP1 Yes-associated protein 1
ZGLP1 zinc finger, GATA-like protein 1