Acute Undifferentiated Leukemia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0280141
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Genes

116 genes associated with the disease Acute Undifferentiated Leukemia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADA adenosine deaminase
ADGRE2 adhesion G protein-coupled receptor E2
ADGRE5 adhesion G protein-coupled receptor E5
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX15 arachidonate 15-lipoxygenase
ANPEP alanyl (membrane) aminopeptidase
BAALC brain and acute leukemia, cytoplasmic
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BCR breakpoint cluster region
CASP9 caspase 9, apoptosis-related cysteine peptidase
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCL3 chemokine (C-C motif) ligand 3
CD34 CD34 molecule
CD38 CD38 molecule
CD93 CD93 molecule
CD96 CD96 molecule
CLEC12A C-type lectin domain family 12, member A
COLEC10 collectin sub-family member 10 (C-type lectin)
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CSF1R colony stimulating factor 1 receptor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSG cathepsin G
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
DEK DEK proto-oncogene
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EGLN1 egl-9 family hypoxia-inducible factor 1
EIF4E eukaryotic translation initiation factor 4E
EPO erythropoietin
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2R coagulation factor II (thrombin) receptor
FAM212A family with sequence similarity 212, member A
FGFR1 fibroblast growth factor receptor 1
FLT3 fms-related tyrosine kinase 3
FN1 fibronectin 1
FOXM1 forkhead box M1
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA2 GATA binding protein 2
GLI2 GLI family zinc finger 2
HHEX hematopoietically expressed homeobox
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLF hepatic leukemia factor
HOXA9 homeobox A9
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGFBP7 insulin-like growth factor binding protein 7
IKZF2 IKAROS family zinc finger 2 (Helios)
IL2RA interleukin 2 receptor, alpha
IL3 interleukin 3
IL33R interleukin 33 receptor
ISG20 interferon stimulated exonuclease gene 20kDa
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KDM1A lysine (K)-specific demethylase 1A
KDM5B lysine (K)-specific demethylase 5B
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLRC4-KLRK1 KLRC4-KLRK1 readthrough
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2A lysine (K)-specific methyltransferase 2A
KRT7 keratin 7, type II
LMO2 LIM domain only 2 (rhombotin-like 1)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MBD2 methyl-CpG binding domain protein 2
MEF2C myocyte enhancer factor 2C
MEIS1 Meis homeobox 1
MME membrane metallo-endopeptidase
MPO myeloperoxidase
MUC1 mucin 1, cell surface associated
MYH11 myosin, heavy chain 11, smooth muscle
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NUP214 nucleoporin 214kDa
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PBX3 pre-B-cell leukemia homeobox 3
PCBP4 poly(rC) binding protein 4
PCDH17 protocadherin 17
PDE7B phosphodiesterase 7B
PHF6 PHD finger protein 6
PMEL premelanosome protein
PML promyelocytic leukemia
PPARG peroxisome proliferator-activated receptor gamma
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCH protein kinase C, eta
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RRAS related RAS viral (r-ras) oncogene homolog
RUNX1 runt-related transcription factor 1
SALL4 spalt-like transcription factor 4
SCLY selenocysteine lyase
SET SET nuclear proto-oncogene
SETBP1 SET binding protein 1
SIX1 SIX homeobox 1
SMC4 structural maintenance of chromosomes 4
SNRPN small nuclear ribonucleoprotein polypeptide N
SPI1 Spi-1 proto-oncogene
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STIL SCL/TAL1 interrupting locus
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TAL1 T-cell acute lymphocytic leukemia 1
TBX1 T-box 1
TERT telomerase reverse transcriptase
TET2 tet methylcytosine dioxygenase 2
TMEM132A transmembrane protein 132A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TRIM62 tripartite motif containing 62
TSPAN3 tetraspanin 3
VEGFA vascular endothelial growth factor A