Acute pancreatitis_Pancreas_GSE3644 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE3644
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Genes

600 genes differentially expressed during Acute pancreatitis_Pancreas_GSE3644 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
AIG1 androgen-induced 1 5.21728
RCC2 regulator of chromosome condensation 2 4.14317
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) 4.06956
RARS arginyl-tRNA synthetase 3.21095
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 3.10055
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 3.03257
EPRS glutamyl-prolyl-tRNA synthetase 2.97552
SBDS Shwachman-Bodian-Diamond syndrome 2.94607
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 2.82813
RCAN3 RCAN family member 3 2.7991
WASF2 WAS protein family, member 2 2.74104
HSPA4L heat shock 70kDa protein 4-like 2.67703
PRDM4 PR domain containing 4 2.65775
RRAS2 related RAS viral (r-ras) oncogene homolog 2 2.62394
PHF10 PHD finger protein 10 2.59263
WDR1 WD repeat domain 1 2.56925
CTSZ cathepsin Z 2.4661
PGK1 phosphoglycerate kinase 1 2.4422
NUP210 nucleoporin 210kDa 2.4337
FBXW11 F-box and WD repeat domain containing 11 2.4316
TAGLN2 transgelin 2 2.39618
KIAA1551 KIAA1551 2.3672
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 2.31118
EIF5 eukaryotic translation initiation factor 5 2.28662
UBAP2 ubiquitin associated protein 2 2.23728
TP53INP1 tumor protein p53 inducible nuclear protein 1 2.22232
DAPK1 death-associated protein kinase 1 2.22157
ACVR1 activin A receptor, type I 2.19252
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 2.11934
MYH9 myosin, heavy chain 9, non-muscle 2.10824
EMP2 epithelial membrane protein 2 2.1018
SMYD2 SET and MYND domain containing 2 2.08284
EPC1 enhancer of polycomb homolog 1 (Drosophila) 2.07505
PREP prolyl endopeptidase 2.05915
ARF6 ADP-ribosylation factor 6 2.0405
RTN4 reticulon 4 2.03966
TMEM11 transmembrane protein 11 2.01649
PKP3 plakophilin 3 2.01484
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 1.96631
OSBPL5 oxysterol binding protein-like 5 1.96019
TJP2 tight junction protein 2 1.90939
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.90178
EZR ezrin 1.89981
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 1.88842
NFYB nuclear transcription factor Y, beta 1.87902
DESI2 desumoylating isopeptidase 2 1.86009
NARS asparaginyl-tRNA synthetase 1.83937
FGFR1 fibroblast growth factor receptor 1 1.81549
KRT18 keratin 18, type I 1.80332
PLEC plectin 1.79033
BZW1 basic leucine zipper and W2 domains 1 1.773
UBE2J1 ubiquitin-conjugating enzyme E2, J1 1.7635
FXYD5 FXYD domain containing ion transport regulator 5 1.76003
BCAR1 breast cancer anti-estrogen resistance 1 1.75065
BCL10 B-cell CLL/lymphoma 10 1.74145
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.73538
HMOX1 heme oxygenase 1 1.71541
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 1.71151
EIF4H eukaryotic translation initiation factor 4H 1.68824
HCCS holocytochrome c synthase 1.6834
FPGS folylpolyglutamate synthase 1.67822
ZFAND5 zinc finger, AN1-type domain 5 1.67818
TMEM185B transmembrane protein 185B 1.67711
UNC13B unc-13 homolog B (C. elegans) 1.66979
SLC7A3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 1.66883
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 1.66509
ERO1L ERO1-like (S. cerevisiae) 1.66066
PICALM phosphatidylinositol binding clathrin assembly protein 1.62795
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.61869
VEGFA vascular endothelial growth factor A 1.60565
IARS isoleucyl-tRNA synthetase 1.60428
AHCYL1 adenosylhomocysteinase-like 1 1.5931
CHIC2 cysteine-rich hydrophobic domain 2 1.58577
CDR2 cerebellar degeneration-related protein 2, 62kDa 1.56913
PPP1R37 protein phosphatase 1, regulatory subunit 37 1.56136
GHITM growth hormone inducible transmembrane protein 1.5389
GTPBP2 GTP binding protein 2 1.52664
DIAPH1 diaphanous-related formin 1 1.50664
STBD1 starch binding domain 1 1.48945
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 1.48373
EIF3C eukaryotic translation initiation factor 3, subunit C 1.47789
GARS glycyl-tRNA synthetase 1.47235
RPL12 ribosomal protein L12 1.46734
DDB1 damage-specific DNA binding protein 1, 127kDa 1.45497
ACTN1 actinin, alpha 1 1.44589
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 1.44459
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 1.43462
NMD3 NMD3 ribosome export adaptor 1.42639
HMGXB3 HMG box domain containing 3 1.42547
TRIO trio Rho guanine nucleotide exchange factor 1.42315
CAB39 calcium binding protein 39 1.41538
PUF60 poly-U binding splicing factor 60KDa 1.3888
EPS8L2 EPS8-like 2 1.38585
GCLC glutamate-cysteine ligase, catalytic subunit 1.38031
FLOT2 flotillin 2 1.37752
UBR5 ubiquitin protein ligase E3 component n-recognin 5 1.36662
KLHL22 kelch-like family member 22 1.36201
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 1.3536
CSTB cystatin B (stefin B) 1.35173
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 1.33983
FAM83H family with sequence similarity 83, member H 1.32733
ATP11A ATPase, class VI, type 11A 1.32308
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 1.32308
ADAM9 ADAM metallopeptidase domain 9 1.32083
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.31291
ATF4 activating transcription factor 4 1.30981
FIZ1 FLT3-interacting zinc finger 1 1.30763
GRB10 growth factor receptor-bound protein 10 1.307
ZNF274 zinc finger protein 274 1.29345
CLIC4 chloride intracellular channel 4 1.29296
ARRDC4 arrestin domain containing 4 1.28656
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.28539
PKNOX1 PBX/knotted 1 homeobox 1 1.28036
KCTD10 potassium channel tetramerization domain containing 10 1.27799
CLIC1 chloride intracellular channel 1 1.27651
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 1.2712
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 1.26436
KRT8 keratin 8, type II 1.25154
YPEL3 yippee-like 3 (Drosophila) 1.24993
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.24906
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.24636
SFT2D2 SFT2 domain containing 2 1.24574
LARS leucyl-tRNA synthetase 1.24396
NUDT22 nudix (nucleoside diphosphate linked moiety X)-type motif 22 1.24205
ERCC1 excision repair cross-complementation group 1 1.23987
AARS alanyl-tRNA synthetase 1.2292
CCNL1 cyclin L1 1.22137
EIF3D eukaryotic translation initiation factor 3, subunit D 1.21471
MFSD6L major facilitator superfamily domain containing 6-like 1.21431
RNPS1 RNA binding protein S1, serine-rich domain 1.21237
PDCD6 programmed cell death 6 1.20182
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 1.20035
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.19924
YAP1 Yes-associated protein 1 1.19577
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.17656
RHOG ras homolog family member G 1.17585
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 1.17323
ZFP64 ZFP64 zinc finger protein 1.17238
WDR5 WD repeat domain 5 1.17229
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.1692
STOML2 stomatin (EPB72)-like 2 1.16563
CPEB4 cytoplasmic polyadenylation element binding protein 4 1.15307
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 1.15271
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 1.15216
KLF3 Kruppel-like factor 3 (basic) 1.15096
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 1.14991
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 1.14746
TLK2 tousled-like kinase 2 1.14681
CDCP1 CUB domain containing protein 1 1.14415
TSC22D1 TSC22 domain family, member 1 1.14102
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.13746
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 1.1293
PSAT1 phosphoserine aminotransferase 1 1.12498
IGSF5 immunoglobulin superfamily, member 5 1.12393
UBIAD1 UbiA prenyltransferase domain containing 1 1.12305
SARS seryl-tRNA synthetase 1.12297
FERMT2 fermitin family member 2 1.10665
TES testin LIM domain protein 1.10303
CNIH4 cornichon family AMPA receptor auxiliary protein 4 1.10044
DUSP16 dual specificity phosphatase 16 1.09921
FOXJ3 forkhead box J3 1.09749
IPO4 importin 4 1.08741
CARM1 coactivator-associated arginine methyltransferase 1 1.08519
NPC1 Niemann-Pick disease, type C1 1.08039
MGEA5 meningioma expressed antigen 5 (hyaluronidase) 1.0797
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 1.07615
PTPRF protein tyrosine phosphatase, receptor type, F 1.06965
CTH cystathionine gamma-lyase 1.06025
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 1.05041
CAPN2 calpain 2, (m/II) large subunit 1.0493
SLC35F5 solute carrier family 35, member F5 1.04379
UBE2D2 ubiquitin-conjugating enzyme E2D 2 1.03994
UBA3 ubiquitin-like modifier activating enzyme 3 1.03926
TPST2 tyrosylprotein sulfotransferase 2 1.02334
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 1.02055
LAPTM4B lysosomal protein transmembrane 4 beta 1.01922
C7ORF25 chromosome 7 open reading frame 25 1.01552
TARS threonyl-tRNA synthetase 1.01551
CDK9 cyclin-dependent kinase 9 1.01474
GLB1 galactosidase, beta 1 1.01338
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 1.0104
SERINC1 serine incorporator 1 1.00917
PTPN12 protein tyrosine phosphatase, non-receptor type 12 1.00479
MAT2A methionine adenosyltransferase II, alpha 1.00205
CARD10 caspase recruitment domain family, member 10 1.00103
ARID5A AT rich interactive domain 5A (MRF1-like) 0.998014
UBE2Z ubiquitin-conjugating enzyme E2Z 0.996344
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 0.995908
ANXA7 annexin A7 0.995282
TGIF1 TGFB-induced factor homeobox 1 0.993705
IER3 immediate early response 3 0.993035
CSRP1 cysteine and glycine-rich protein 1 0.99117
SFPQ splicing factor proline/glutamine-rich 0.990721
SON SON DNA binding protein 0.985286
INSIG2 insulin induced gene 2 0.981596
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.979027
SOCS6 suppressor of cytokine signaling 6 0.973039
INTS6 integrator complex subunit 6 0.970513
QTRT1 queuine tRNA-ribosyltransferase 1 0.964707
RAP1B RAP1B, member of RAS oncogene family 0.962418
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.960343
KLF4 Kruppel-like factor 4 (gut) 0.960309
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.959194
STAMBPL1 STAM binding protein-like 1 0.958656
DAXX death-domain associated protein 0.954112
KRT80 keratin 80, type II 0.949105
OCLN occludin 0.948622
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 0.943388
NOP56 NOP56 ribonucleoprotein 0.940727
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 0.939849
ELAVL1 ELAV like RNA binding protein 1 0.93726
ATF5 activating transcription factor 5 0.935087
SRM spermidine synthase 0.933468
CTBP1 C-terminal binding protein 1 0.932501
RNF208 ring finger protein 208 0.931524
UHRF1BP1L UHRF1 binding protein 1-like 0.928276
DSTN destrin (actin depolymerizing factor) 0.922624
RBM18 RNA binding motif protein 18 0.921936
KLF9 Kruppel-like factor 9 0.921237
QRICH1 glutamine-rich 1 0.921188
SH2B3 SH2B adaptor protein 3 0.918918
PLCL2 phospholipase C-like 2 0.915227
MAN1B1 mannosidase, alpha, class 1B, member 1 0.914503
EFHD2 EF-hand domain family, member D2 0.913862
RBM17 RNA binding motif protein 17 0.913781
KAZN kazrin, periplakin interacting protein 0.912534
HAX1 HCLS1 associated protein X-1 0.905972
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 0.90459
AMMECR1L AMMECR1-like 0.904036
ACTN4 actinin, alpha 4 0.902994
MARK2 MAP/microtubule affinity-regulating kinase 2 0.902244
FAM110C family with sequence similarity 110, member C 0.89806
PDLIM5 PDZ and LIM domain 5 0.895006
LRRC59 leucine rich repeat containing 59 0.89444
GGNBP2 gametogenetin binding protein 2 0.888209
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 0.887131
ZNF598 zinc finger protein 598 0.885708
NFIL3 nuclear factor, interleukin 3 regulated 0.885003
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 0.88057
MAP2K3 mitogen-activated protein kinase kinase 3 0.879215
NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 0.876295
LNX2 ligand of numb-protein X 2 0.874868
XPO6 exportin 6 0.873423
SDC1 syndecan 1 0.868552
IFRD1 interferon-related developmental regulator 1 0.867897
NGLY1 N-glycanase 1 0.866459
IER2 immediate early response 2 0.865856
NABP1 nucleic acid binding protein 1 0.864365
ELF4 E74-like factor 4 (ets domain transcription factor) 0.860448
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 0.859738
COMMD7 COMM domain containing 7 0.858561
HARS histidyl-tRNA synthetase 0.856738
ACPP acid phosphatase, prostate 0.849513
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.844048
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.843628
GJB2 gap junction protein, beta 2, 26kDa 0.843544
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.840722
M6PR mannose-6-phosphate receptor (cation dependent) 0.837972
JAK2 Janus kinase 2 0.836538
RAB6A RAB6A, member RAS oncogene family 0.834573
COL7A1 collagen, type VII, alpha 1 0.831813
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.830832
UBE2N ubiquitin-conjugating enzyme E2N 0.828208
EIF6 eukaryotic translation initiation factor 6 0.825703
HILPDA hypoxia inducible lipid droplet-associated 0.825601
SREBF2 sterol regulatory element binding transcription factor 2 0.82554
STK40 serine/threonine kinase 40 0.824182
HIPK2 homeodomain interacting protein kinase 2 0.821562
AEN apoptosis enhancing nuclease 0.82043
ARL14EP ADP-ribosylation factor-like 14 effector protein 0.819885
WIPI2 WD repeat domain, phosphoinositide interacting 2 0.819805
SUN2 Sad1 and UNC84 domain containing 2 0.819339
PQLC1 PQ loop repeat containing 1 0.818939
PNO1 partner of NOB1 homolog (S. cerevisiae) 0.81374
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 0.811781
CLTC clathrin, heavy chain (Hc) 0.809559
SDCBP syndecan binding protein (syntenin) 0.807564
RALGDS ral guanine nucleotide dissociation stimulator 0.80663
BRIX1 BRX1, biogenesis of ribosomes 0.799382
TROVE2 TROVE domain family, member 2 0.798728
LAP3 leucine aminopeptidase 3 0.797854
WSB1 WD repeat and SOCS box containing 1 0.79162
MYL12B myosin, light chain 12B, regulatory 0.787254
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 0.786301
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.782788
SOCS4 suppressor of cytokine signaling 4 0.77905
SGMS1 sphingomyelin synthase 1 0.776215
ANXA3 annexin A3 0.776177
MARCH5 membrane-associated ring finger (C3HC4) 5 0.77567
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.775182
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.77291
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.770771
USP43 ubiquitin specific peptidase 43 0.769627
WDR75 WD repeat domain 75 0.767729
ANO1 anoctamin 1, calcium activated chloride channel 0.767076
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 0.766048
KCNK5 potassium channel, two pore domain subfamily K, member 5 0.765217
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 0.764623
CTSV cathepsin V 0.764322
CYB5R1 cytochrome b5 reductase 1 0.756449

decreased expression

Symbol Name Standardized Value
PAM peptidylglycine alpha-amidating monooxygenase -4.81618
AHCY adenosylhomocysteinase -4.58298
CTAGE5 CTAGE family, member 5 -3.52556
SPHK2 sphingosine kinase 2 -3.50358
SEPP1 selenoprotein P, plasma, 1 -3.45184
PEX11A peroxisomal biogenesis factor 11 alpha -3.43165
SRSF9 serine/arginine-rich splicing factor 9 -3.39824
SYPL1 synaptophysin-like 1 -3.326
GRPEL2 GrpE-like 2, mitochondrial (E. coli) -3.29123
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -3.2837
CCND1 cyclin D1 -3.21953
VKORC1 vitamin K epoxide reductase complex, subunit 1 -3.15548
PBX3 pre-B-cell leukemia homeobox 3 -3.10093
LTBP4 latent transforming growth factor beta binding protein 4 -3.02758
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -2.87367
PXMP4 peroxisomal membrane protein 4, 24kDa -2.82552
POLM polymerase (DNA directed), mu -2.81585
SYNGR2 synaptogyrin 2 -2.76814
H2AFV H2A histone family, member V -2.64133
EI24 etoposide induced 2.4 -2.58099
TCP1 t-complex 1 -2.57481
GRAMD3 GRAM domain containing 3 -2.55536
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -2.51549
CTSD cathepsin D -2.50204
CHRAC1 chromatin accessibility complex 1 -2.46695
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -2.36673
RAD1 RAD1 checkpoint DNA exonuclease -2.34783
RAB2B RAB2B, member RAS oncogene family -2.2592
GPC4 glypican 4 -2.25689
ASB8 ankyrin repeat and SOCS box containing 8 -2.20308
SRSF10 serine/arginine-rich splicing factor 10 -2.19817
PEX2 peroxisomal biogenesis factor 2 -2.1796
PSEN1 presenilin 1 -2.15363
DEPTOR DEP domain containing MTOR-interacting protein -2.14562
GLOD4 glyoxalase domain containing 4 -2.10069
RB1CC1 RB1-inducible coiled-coil 1 -2.06895
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.06835
CHMP5 charged multivesicular body protein 5 -2.06598
CCDC92 coiled-coil domain containing 92 -2.04121
GNS glucosamine (N-acetyl)-6-sulfatase -1.97073
SETDB1 SET domain, bifurcated 1 -1.96655
SERF2 small EDRK-rich factor 2 -1.96485
ELP3 elongator acetyltransferase complex subunit 3 -1.92039
HP1BP3 heterochromatin protein 1, binding protein 3 -1.91816
PSENEN presenilin enhancer gamma secretase subunit -1.91491
TRAPPC10 trafficking protein particle complex 10 -1.91392
LGALS8 lectin, galactoside-binding, soluble, 8 -1.88636
FGFBP1 fibroblast growth factor binding protein 1 -1.88326
DRAM2 DNA-damage regulated autophagy modulator 2 -1.8823
NUP88 nucleoporin 88kDa -1.87351
TNRC6A trinucleotide repeat containing 6A -1.87065
LMAN1 lectin, mannose-binding, 1 -1.8651
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -1.85589
RAB21 RAB21, member RAS oncogene family -1.85284
SHE Src homology 2 domain containing E -1.84964
FECH ferrochelatase -1.84808
CLDN10 claudin 10 -1.84537
ZC3H8 zinc finger CCCH-type containing 8 -1.84127
SEC24C SEC24 family member C -1.83079
MRPS21 mitochondrial ribosomal protein S21 -1.78431
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -1.75269
RSU1 Ras suppressor protein 1 -1.74402
RHOT1 ras homolog family member T1 -1.74343
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -1.72093
GABARAP GABA(A) receptor-associated protein -1.70875
GRID1 glutamate receptor, ionotropic, delta 1 -1.70428
BHLHA15 basic helix-loop-helix family, member a15 -1.6849
MAGT1 magnesium transporter 1 -1.68351
LGALS4 lectin, galactoside-binding, soluble, 4 -1.66315
CHAC2 ChaC, cation transport regulator homolog 2 (E. coli) -1.66182
LUC7L2 LUC7-like 2 (S. cerevisiae) -1.65895
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa -1.65076
EID1 EP300 interacting inhibitor of differentiation 1 -1.64005
SPOP speckle-type POZ protein -1.64001
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 -1.6233
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -1.62069
FOXD1 forkhead box D1 -1.60569
NCOA1 nuclear receptor coactivator 1 -1.60089
S1PR1 sphingosine-1-phosphate receptor 1 -1.59647
CNOT7 CCR4-NOT transcription complex, subunit 7 -1.58581
ZNF292 zinc finger protein 292 -1.58375
SSBP3 single stranded DNA binding protein 3 -1.5828
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 -1.57689
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -1.57465
ST7L suppression of tumorigenicity 7 like -1.56862
PHYHD1 phytanoyl-CoA dioxygenase domain containing 1 -1.5589
SRP9 signal recognition particle 9kDa -1.55672
CHRM1 cholinergic receptor, muscarinic 1 -1.5567
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -1.55472
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 -1.54337
CCKAR cholecystokinin A receptor -1.53158
PAH phenylalanine hydroxylase -1.52964
SUN1 Sad1 and UNC84 domain containing 1 -1.52194
HNRNPR heterogeneous nuclear ribonucleoprotein R -1.51663
SRSF6 serine/arginine-rich splicing factor 6 -1.51288
MRPS14 mitochondrial ribosomal protein S14 -1.51003
SASH1 SAM and SH3 domain containing 1 -1.48944
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 -1.46507
IFI30 interferon, gamma-inducible protein 30 -1.4606
HIGD2A HIG1 hypoxia inducible domain family, member 2A -1.46035
FBXO8 F-box protein 8 -1.45974
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -1.4562
VTI1B vesicle transport through interaction with t-SNAREs 1B -1.4514
ARG2 arginase 2 -1.44494
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 -1.44441
ZNF445 zinc finger protein 445 -1.44081
CETN2 centrin, EF-hand protein, 2 -1.43708
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) -1.42884
MMP2 matrix metallopeptidase 2 -1.41549
RTN3 reticulon 3 -1.41307
EXOC4 exocyst complex component 4 -1.41027
SHFM1 split hand/foot malformation (ectrodactyly) type 1 -1.40579
OPN1LW opsin 1 (cone pigments), long-wave-sensitive -1.40355
USP1 ubiquitin specific peptidase 1 -1.40279
RBM5 RNA binding motif protein 5 -1.39783
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -1.39759
CACHD1 cache domain containing 1 -1.39714
CAPN7 calpain 7 -1.3913
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -1.39059
EBAG9 estrogen receptor binding site associated, antigen, 9 -1.38696
GOLPH3L golgi phosphoprotein 3-like -1.38514
ITPKB inositol-trisphosphate 3-kinase B -1.37743
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -1.37611
CDC123 cell division cycle 123 -1.37348
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha -1.36216
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -1.36213
MAG myelin associated glycoprotein -1.35313
DHRS3 dehydrogenase/reductase (SDR family) member 3 -1.35047
TM2D3 TM2 domain containing 3 -1.34827
UFC1 ubiquitin-fold modifier conjugating enzyme 1 -1.34405
DEXI Dexi homolog (mouse) -1.33761
CEP68 centrosomal protein 68kDa -1.33486
DBT dihydrolipoamide branched chain transacylase E2 -1.33446
SH3BGRL SH3 domain binding glutamate-rich protein like -1.33382
MPC2 mitochondrial pyruvate carrier 2 -1.3314
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -1.31859
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -1.31426
AZIN1 antizyme inhibitor 1 -1.31255
C6ORF120 chromosome 6 open reading frame 120 -1.30999
HNMT histamine N-methyltransferase -1.30435
PDCL phosducin-like -1.30145
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -1.30145
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -1.29849
AKAP8 A kinase (PRKA) anchor protein 8 -1.29654
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa -1.28653
KCMF1 potassium channel modulatory factor 1 -1.2827
ETNK1 ethanolamine kinase 1 -1.28134
UCKL1 uridine-cytidine kinase 1-like 1 -1.28124
ANKFY1 ankyrin repeat and FYVE domain containing 1 -1.27761
PHLDB1 pleckstrin homology-like domain, family B, member 1 -1.27723
RHBDF1 rhomboid 5 homolog 1 (Drosophila) -1.27686
CNOT6L CCR4-NOT transcription complex, subunit 6-like -1.2762
ECI2 enoyl-CoA delta isomerase 2 -1.27152
SH3GLB1 SH3-domain GRB2-like endophilin B1 -1.26536
CIAO1 cytosolic iron-sulfur assembly component 1 -1.26023
CPEB3 cytoplasmic polyadenylation element binding protein 3 -1.24977
AURKAIP1 aurora kinase A interacting protein 1 -1.23295
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -1.22994
ARGLU1 arginine and glutamate rich 1 -1.22743
RASL11B RAS-like, family 11, member B -1.22262
ISOC1 isochorismatase domain containing 1 -1.22246
ECI1 enoyl-CoA delta isomerase 1 -1.21892
ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 -1.21686
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) -1.20012
TBCEL tubulin folding cofactor E-like -1.19752
HIBADH 3-hydroxyisobutyrate dehydrogenase -1.19741
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -1.19304
AK3 adenylate kinase 3 -1.18995
TCF12 transcription factor 12 -1.18994
NBR1 neighbor of BRCA1 gene 1 -1.188
PTEN phosphatase and tensin homolog -1.17989
SEPHS2 selenophosphate synthetase 2 -1.17982
TSPAN31 tetraspanin 31 -1.1795
SEC16A SEC16 homolog A (S. cerevisiae) -1.16559
AP3S2 adaptor-related protein complex 3, sigma 2 subunit -1.15984
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -1.15259
SC5D sterol-C5-desaturase -1.15163
CDC5L cell division cycle 5-like -1.14766
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -1.14584
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -1.14283
DNASE1L3 deoxyribonuclease I-like 3 -1.14047
EMC9 ER membrane protein complex subunit 9 -1.13667
YY1 YY1 transcription factor -1.13525
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -1.13423
C14ORF1 chromosome 14 open reading frame 1 -1.13345
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa -1.13178
IVD isovaleryl-CoA dehydrogenase -1.12985
ATP13A1 ATPase type 13A1 -1.12586
NXF1 nuclear RNA export factor 1 -1.12233
SF3B2 splicing factor 3b, subunit 2, 145kDa -1.11914
ATRAID all-trans retinoic acid-induced differentiation factor -1.11785
C1QC complement component 1, q subcomponent, C chain -1.10934
H2AFY H2A histone family, member Y -1.10884
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -1.10563
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -1.10423
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) -1.1015
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -1.09881
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -1.09857
COPZ1 coatomer protein complex, subunit zeta 1 -1.09632
FOXA2 forkhead box A2 -1.09564
BAG4 BCL2-associated athanogene 4 -1.0926
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 -1.08688
C1ORF35 chromosome 1 open reading frame 35 -1.08569
LBR lamin B receptor -1.08521
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 -1.0851
TSPAN7 tetraspanin 7 -1.08178
FAM160B1 family with sequence similarity 160, member B1 -1.07672
TFG TRK-fused gene -1.07666
DERA deoxyribose-phosphate aldolase (putative) -1.06999
GSTM5 glutathione S-transferase mu 5 -1.06695
SYNJ2BP synaptojanin 2 binding protein -1.06652
OPA1 optic atrophy 1 (autosomal dominant) -1.06543
DCTPP1 dCTP pyrophosphatase 1 -1.06525
TMBIM4 transmembrane BAX inhibitor motif containing 4 -1.06222
TOB1 transducer of ERBB2, 1 -1.06046
AK5 adenylate kinase 5 -1.06041
TMEM184A transmembrane protein 184A -1.05179
SCP2 sterol carrier protein 2 -1.05168
DAP death-associated protein -1.04921
VAMP7 vesicle-associated membrane protein 7 -1.04774
SDHAF1 succinate dehydrogenase complex assembly factor 1 -1.04774
LETMD1 LETM1 domain containing 1 -1.04609
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa -1.04492
RPL19 ribosomal protein L19 -1.04479
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 -1.04123
MKNK1 MAP kinase interacting serine/threonine kinase 1 -1.04009
PRPF39 pre-mRNA processing factor 39 -1.03875
NONO non-POU domain containing, octamer-binding -1.03781
DRG1 developmentally regulated GTP binding protein 1 -1.03683
ERCC6L excision repair cross-complementation group 6-like -1.02852
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI -1.02708
SPAST spastin -1.02537
STAMBP STAM binding protein -1.02509
ISCU iron-sulfur cluster assembly enzyme -1.02381
LZTFL1 leucine zipper transcription factor-like 1 -1.02324
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 -1.02262
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -1.01888
HIP1 huntingtin interacting protein 1 -1.0161
ERMP1 endoplasmic reticulum metallopeptidase 1 -1.01565
C1ORF43 chromosome 1 open reading frame 43 -1.00992
MRPL20 mitochondrial ribosomal protein L20 -1.00953
CSE1L CSE1 chromosome segregation 1-like (yeast) -1.00893
CBX1 chromobox homolog 1 -1.00525
TRIM37 tripartite motif containing 37 -1.00447
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.999987
RPL37A ribosomal protein L37a -0.997947
UNC50 unc-50 homolog (C. elegans) -0.99602
RPUSD1 RNA pseudouridylate synthase domain containing 1 -0.994465
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -0.992189
ZNF148 zinc finger protein 148 -0.990876
SLIRP SRA stem-loop interacting RNA binding protein -0.988517
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -0.984472
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8 -0.98099
ZADH2 zinc binding alcohol dehydrogenase domain containing 2 -0.980463
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin -0.979086
LARP1 La ribonucleoprotein domain family, member 1 -0.978219
INADL InaD-like (Drosophila) -0.973055
ROR1 receptor tyrosine kinase-like orphan receptor 1 -0.972697
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) -0.971806
FGFR1OP2 FGFR1 oncogene partner 2 -0.971011
UFD1L ubiquitin fusion degradation 1 like (yeast) -0.97033
CARKD carbohydrate kinase domain containing -0.964031
SNX3 sorting nexin 3 -0.958858
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1 -0.956211
SSFA2 sperm specific antigen 2 -0.953156
PLBD1 phospholipase B domain containing 1 -0.951683
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.951478
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 -0.948245
GPX4 glutathione peroxidase 4 -0.937436
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.937292
QPCTL glutaminyl-peptide cyclotransferase-like -0.933555
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -0.928468
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 -0.928093
RPL26 ribosomal protein L26 -0.924804
ARCN1 archain 1 -0.924111
LPL lipoprotein lipase -0.922993
C9ORF3 chromosome 9 open reading frame 3 -0.920553
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G -0.919907
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -0.917986
CLN5 ceroid-lipofuscinosis, neuronal 5 -0.917768
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -0.914366
MRFAP1 Morf4 family associated protein 1 -0.913214
SEL1L sel-1 suppressor of lin-12-like (C. elegans) -0.910298
ADCY6 adenylate cyclase 6 -0.905298
RRP36 ribosomal RNA processing 36 homolog (S. cerevisiae) -0.904363
C1ORF52 chromosome 1 open reading frame 52 -0.900569
RPL15 ribosomal protein L15 -0.8997
CLDN8 claudin 8 -0.898938
LBH limb bud and heart development -0.89862
TMEM131 transmembrane protein 131 -0.89816
GRIA4 glutamate receptor, ionotropic, AMPA 4 -0.892816
HSPG2 heparan sulfate proteoglycan 2 -0.890371
CRYBB3 crystallin, beta B3 -0.890336
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa -0.888526
PLS3 plastin 3 -0.886786
NSDHL NAD(P) dependent steroid dehydrogenase-like -0.886479
SERINC3 serine incorporator 3 -0.88413
METTL20 methyltransferase like 20 -0.883719
REEP1 receptor accessory protein 1 -0.882835
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.870291
Funding